Efficient targeting of adenoviral vectors to integrin positive vascular cells utilizing a CAR-cyclic RGD linker protein

Biochemical and Biophysical Research Communications

Volumn 338, Issue 2, 2005, Pages 847-854

  Krom, Y D ^a   Gras, J C E ^a   Frants, R R ^a   Havekes, L M ^a,b   Van Berkel, T J ^c   Biessen, E A L ^c   Van Dijk, K Willems ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b TNO   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Adenovirus; Cyclic RGD peptide; Endothelial cells; Targeting; Vascular smooth muscle cells

Indexed keywords

ADENOVIRUS VECTOR; ARGINYLGLYCYLASPARTIC ACID; AVIDIN; COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR; CYCLOPEPTIDE; GREEN FLUORESCENT PROTEIN; INTEGRIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOTINYLATION; CELL FRACTIONATION; CELL LINE; ENDOTHELIUM CELL; GENE EXPRESSION; GENE TARGETING; HEART; HEMANGIOENDOTHELIOMA; HUMAN; HUMAN CELL; INFECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; TRANSGENE; UMBILICAL VEIN; VASCULAR SMOOTH MUSCLE;

ADENOVIRIDAE; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; GENETIC VECTORS; HUMANS; INTEGRIN ALPHAVBETA3; INTEGRINS; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OLIGOPEPTIDES; PROTEIN ENGINEERING; RECEPTORS, VITRONECTIN; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

ADENOVIRIDAE; ANIMALIA; COXSACKIEVIRUS;

EID: 27744535666     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.10.073     Document Type: Article

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