Study of a novel brain relatively specific gene LRRC4 involved in glioma tumorigenesis suppression using the Tet-on system

Acta Biochimica et Biophysica Sinica

Volumn 37, Issue 8, 2005, Pages 532-540

  Zhang, Qiu Hong ^a   Wang, Li Li ^a   Cao, Li ^a   Peng, Cong ^a   Li, Xiao Ling ^a   Tang, Ke ^a   Li, Wei Fang ^a   Liao, Ping ^a   Wang, Jie Ru ^a   Li, Gui Yuan ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Cell cycle delay; Cell proliferation; LRRC4; Tumorigencity

Indexed keywords

CELL CYCLE PROTEIN; LRRC4 PROTEIN, HUMAN; NERVE PROTEIN; TETRACYCLINE;

ANIMAL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; BRAIN TUMOR; CELL PROLIFERATION; GENETIC TRANSFECTION; GENETICS; GLIOMA; HUMAN; MALE; METABOLISM; METHODOLOGY; MOUSE; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

ANIMALS; APOPTOSIS; BRAIN NEOPLASMS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; GENES, TUMOR SUPPRESSOR; GLIOMA; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NERVE TISSUE PROTEINS; TETRACYCLINE; TRANSFECTION;

EID: 27744442168     PISSN: 16729145     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1745-7270.2005.00079.x     Document Type: Article

References (36)

1. Kleihues P, Cavenee WK. Pathology and Genetics of Tumors of the Nervous System. Lyon: IARC Press 2000
2. Rasheed BK, Wiltshire RN, Bigner SH, Bigner DD. Molecular pathogenesis of malignant gliomas. Curr Opin Oncol 1999, 11: 162-167
3. Ranuncolo SM, Varela M, Morandi A, Lastiri J, Christiansen S, Bal de Kier Joffe E, Pallotta MG et al. Prognostic value of Mdm2, p53 and p16 in patients with astrocytomas. J Neurooncol 2004, 68: 113-121
4. Phatak P, Selvi SK, Divya T, Hegde AS, Hegde S, Somasundaram K. Alterations in tumor suppressor gene p53 in human gliomas from Indian patients. J Biosci 2002, 27: 673-678
5. Smith JS, Tachibana I, Passe SM, Huntley BK, Borell TJ, Iturria N, O'Fallon RJ et al. PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiform. J Natl Cancer Inst 2001, 93: 1246-1256
6. Mahaley MS, Mettlin CJ, Natarajan N, Laws ER, Peace BB. National survey of patterns of care for brain tumor patients. J Neurosurg 1989, 71: 826-836
7. Schrijvers D, Vermorken JB. Update on the taxoids and other new agents in head and neck cancer therapy. Curr Opin Oncol 1998, 10: 233-241
8. Meijer L, Kim SH. Chemical inhibitors of cyclin-dependent kinases. Methods Enzymol 1997, 283: 113-128
9. Wang JR, Qian J, Dong L, Li XL, Tan C, Li J, Li GY et al. Identification of LRRC4, a novel member of Leucine Repeat (LRR) Superfamily and its expression analysis in brain tumor. Prog Biochem Biophys 2002, 29: 233-239
10. Tan GL, Xiao JY, Tian YQ, Deng LW, Jiang N, Zhan FH, Li GY. Analysis of deleted mapping on chromosome 7q31.3-36 in nasopharyngeal carcinoma. Chin J Otorhinolaryngology-Skull Base 1998, 4: 165-171
11. Wang JR, Li XL, Fan SQ, Tan C, Xiang JJ, Tang K, Wang R, Li GY. Expression of LRRC4 has the potential to decrease the growth rate and tumorigenesis of glioblastoma cell line U251. Ai Zheng 2003, 22: 897-902
12. Gossen M, Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 1992, 89: 5547-5551
13. Gossen M, Freundlieb S, Bender G, Muller G, Hillen W, Bujard H. Transcriptional activation by tetracyclines in mammalian cells. Science 1995, 268: 1766-1769
14. Shockett PE, Schatz DG. Diverse strategies for tetracycline-regulated inducible gene expression. Proc Natl Acad Sci USA 1996, 93: 5173-5176
15. Palmiter RD. Molecular biology of metallothionein gene expression. Experientia Suppl 1987, 52: 63-80
16. Sadowski I. Uses for GAL4 expression in mammalian cells. Genet Eng 1995, 17: 119-148
17. Verri T, Argenton F, Tomanin R, Scarpa M, Storelli C, Costa R, Colombo L et al. The bacteriophage T7 binary system activates transient transgene expression in zebrafish (Danio rerio) embryos. Biochem Biophys Res Commun 1997, 237: 492-495
18. Bienz M, Pelham HR. Heat shock regulatory elements function as an inducible enhancer in the Xenopus hsp70 gene and when linked to a heterologous promoter. Cell 1986, 45: 753-760
19. No D, Yao TP, Evans RM. Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Proc Natl Acad Sci USA 1996, 93: 3346-3351
20. van Craenenbroeck K, Vanhoenacker P, Leysen JE, Haegeman G. Evaluation of the tetracycline- and ecdysone-inducible systems for expression of neurotransmitter receptors in mammalian cells. Eur J Neurosci 2001, 14: 968-976
21. McDonald ER III, El-Deiry WS. Checkpoint genes in cancer. Ann Med 2001, 33: 113-122
22. Harper JW, Adams PD. Cyclin-dependent kinases. Chem Rev 2001, 101: 2511-2526
23. 1 phase of the human cell cycle. Science 1992, 257: 1689-1694
24. Zerfass-Thome K, Schulze A, Zwerschke W, Vogt B, Helin K, Bartek J, Henglein B et al. p27KIP1 blocks cyclin E-dependent transactivation of cyclin A gene expression. Mol Cell Biol 1997, 17: 407-415
25. Dyson N. The regulation of E2F by pRb-family proteins. Genes Dev 1998, 12: 2245-2262
26. Nevins JR. Toward an understanding of the functional complexity of the E2F and the retinoblastoma families. Cell Growth Differ 1998, 9: 585-593
27. Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown JP, Sedivy JM et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 1998, 282: 1497-1501
28. Rao S, Lowe M, Herliczek TW, Keyomarsi K. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53. Oncogene 1998, 17: 2393-2402
29. Rao S, Porter D, Chen X, Herliczek T, Lowe M, Keyomarsi K. Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase. Proc Natl Acad Sci USA 1999, 96: 7797-7802
30. Cip. Biochem Pharmacol 2003, 65: 1777-1785
31. KIP1. Biochem Biophys Res Commun 2001, 285: 773-781
32. 1-S arrest and apoptosis via p53/p21Waf1 pathway in glioma cell. Biochem Biophys Res Commun 2004, 317: 902-908
33. Cho JW, Jeong YW, Kim KS, Oh JY, Park JC, Lee JC, Back WK et al. p21 (WAF1) is associated with CDK2 and CDK4 protein during HL-60 cell differentiation by TPA treatment. Cell Prolif 2001, 34: 267-274
34. Andl CD, Mizushima T, Nakagawa H, Oyama K, Harada H, Chruma K, Herlyn M et al. Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo. J Biol Chem 2003, 278: 1824-1830
35. Steinbach JP, Klumpp A, Wolburg H, Weller M. Inhibition of epidermal growth factor receptor signaling protects human malignant glioma cells from hypoxia-induced cell death. Cancer Res 2004, 64: 1575-1578
36. Sah JF, Balasubramanian S, Eckert RL, Rorke EA. Epigallocatechin-3- gallate inhibits epidermal growth factor receptor signaling pathway: Evidence for direct inhibition of ERK1/2 and AKT kinases. J Biol Chem 2004, 279: 12755-12762