-
1
-
-
0033569516
-
Pharmacogenomics: Translating functional genomics into rational therapeutics
-
Evans WE and Relling MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 1999; 286:487-491.
-
(1999)
Science
, vol.286
, pp. 487-491
-
-
Evans, W.E.1
Relling, M.V.2
-
2
-
-
0037421590
-
Pharmacogenomics - Drug disposition, drug targets, and side effects
-
Evans WE and McLeod HL. Pharmacogenomics - drug disposition, drug targets, and side effects. N Engl J Med 2003; 348:538-549.
-
(2003)
N Engl J Med
, vol.348
, pp. 538-549
-
-
Evans, W.E.1
McLeod, H.L.2
-
3
-
-
0030995879
-
Molecular mechanisms of genetic polymorphisms of drug metabolism
-
Meyer UA and Zanger UM. Molecular mechanisms of genetic polymorphisms of drug metabolism. Annu Rev Pharmacol Toxicol 1997; 37:269-296.
-
(1997)
Annu Rev Pharmacol Toxicol
, vol.37
, pp. 269-296
-
-
Meyer, U.A.1
Zanger, U.M.2
-
4
-
-
0035987212
-
Cytochrome P450 pharmacogenetics in drug development: In vitro studies and clinical consequences
-
Rodrigues AD and Rushmore TH. Cytochrome P450 pharmacogenetics in drug development: in vitro studies and clinical consequences. Curr Drug Metab 2002; 3:289-309.
-
(2002)
Curr Drug Metab
, vol.3
, pp. 289-309
-
-
Rodrigues, A.D.1
Rushmore, T.H.2
-
5
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockmoller J, Johne A, et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 2000; 97:3473-3478.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Brockmoller, J.5
Johne, A.6
-
6
-
-
0033601257
-
A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters
-
Hsiang B, Zhu Y, Wang Z, Wu Y, Sasseville V, Yang WP, et al. A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters. J Biol Chem 1999; 274:37161-37168.
-
(1999)
J Biol Chem
, vol.274
, pp. 37161-37168
-
-
Hsiang, B.1
Zhu, Y.2
Wang, Z.3
Wu, Y.4
Sasseville, V.5
Yang, W.P.6
-
7
-
-
0037733365
-
A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane
-
Konig J, Cui Y, Nies AT, Keppler D. A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane. Am J Physiol Gastrointest Liver Physiol 2000; 278:G156-G164.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.278
-
-
Konig, J.1
Cui, Y.2
Nies, A.T.3
Keppler, D.4
-
8
-
-
0034709561
-
Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family
-
Tamai I, Nezu J, Uchino H, Sai Y, Oku A, Shimane M, et al. Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family. Biochem Biophys Res Commun 2000; 273:251-260.
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 251-260
-
-
Tamai, I.1
Nezu, J.2
Uchino, H.3
Sai, Y.4
Oku, A.5
Shimane, M.6
-
9
-
-
0040368659
-
Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1
-
Abe T, Kakyo M, Tokui T, Nakagomi R, Nishio T, Nakai D, et al. Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. J Biol Chem 1999; 274:17159-17163.
-
(1999)
J Biol Chem
, vol.274
, pp. 17159-17163
-
-
Abe, T.1
Kakyo, M.2
Tokui, T.3
Nakagomi, R.4
Nishio, T.5
Nakai, D.6
-
10
-
-
0035971239
-
Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6
-
Cui Y, Konig J, Leier I, Buchholz U, Keppler D. Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6. J Biol Chem 2001; 276:9626-9630.
-
(2001)
J Biol Chem
, vol.276
, pp. 9626-9630
-
-
Cui, Y.1
Konig, J.2
Leier, I.3
Buchholz, U.4
Keppler, D.5
-
11
-
-
0034857677
-
Functional characterization of human organic anion transporting polypeptide B (OATP-B) in comparison with liver-specific OATP-C
-
Tamai I, Nozawa T, Koshida M, Nezu J, Sai Y, Tsuji A. Functional characterization of human organic anion transporting polypeptide B (OATP-B) in comparison with liver-specific OATP-C. Pharm Res 2001; 18:1262-1269.
-
(2001)
Pharm Res
, vol.18
, pp. 1262-1269
-
-
Tamai, I.1
Nozawa, T.2
Koshida, M.3
Nezu, J.4
Sai, Y.5
Tsuji, A.6
-
12
-
-
18644368162
-
A naturally occurring mutation in the SLC21A6 gene causing impaired membrane localization of the hepatocyte uptake transporter
-
Michalski C, Cui Y, Nies AT, Nuessler AK, Neuhaus P, Zanger UM, et al. A naturally occurring mutation in the SLC21A6 gene causing impaired membrane localization of the hepatocyte uptake transporter. J Biol Chem 2002; 277:43058-43063.
-
(2002)
J Biol Chem
, vol.277
, pp. 43058-43063
-
-
Michalski, C.1
Cui, Y.2
Nies, A.T.3
Nuessler, A.K.4
Neuhaus, P.5
Zanger, U.M.6
-
13
-
-
0035929574
-
Polymorphisms in OATP-C: Identification of multiple allelic variants associated with altered transport activity among European- and African-Americans
-
Tirona RG, Leake BF, Merino G, Kim RB. Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans. J Biol Chem 2001; 276:35669-35675.
-
(2001)
J Biol Chem
, vol.276
, pp. 35669-35675
-
-
Tirona, R.G.1
Leake, B.F.2
Merino, G.3
Kim, R.B.4
-
14
-
-
0036073404
-
Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): Allele frequencies in the Japanese population and functional analysis
-
Nozawa T, Nakajima M, Tamai I, Noda K, Nezu J, Sai Y, et al. Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis. J Pharmacol Exp Ther 2002; 302:804-813.
-
(2002)
J Pharmacol Exp Ther
, vol.302
, pp. 804-813
-
-
Nozawa, T.1
Nakajima, M.2
Tamai, I.3
Noda, K.4
Nezu, J.5
Sai, Y.6
-
15
-
-
0038209381
-
Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: Consequences for pravastatin pharmacokinetics
-
Nishizato Y, Ieiri I, Suzuki H, Kimura M, Kawabata K, Hirota T, et al. Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics. Clin Pharmacol Ther 2003; 73:554-565.
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 554-565
-
-
Nishizato, Y.1
Ieiri, I.2
Suzuki, H.3
Kimura, M.4
Kawabata, K.5
Hirota, T.6
-
16
-
-
0037155204
-
Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2)
-
6 Sasaki M, Suzuki H, Ito K, Abe T, Sugiyama Y. Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2). J Biol Chem 2002; 277:6497-6503.
-
(2002)
J Biol Chem
, vol.277
, pp. 6497-6503
-
-
Sasaki, M.1
Suzuki, H.2
Ito, K.3
Abe, T.4
Sugiyama, Y.5
-
17
-
-
0034019305
-
Characterization of inducible nature of MRP3 in rat liver
-
Ogawa K, Suzuki H, Hirohashi T, Ishikawa T, Meier PJ, Hirose K, et al. Characterization of inducible nature of MRP3 in rat liver. Am J Physiol Gastroiniest Liver Physiol 2000; 278:G438-G446.
-
(2000)
Am J Physiol Gastroiniest Liver Physiol
, vol.278
-
-
Ogawa, K.1
Suzuki, H.2
Hirohashi, T.3
Ishikawa, T.4
Meier, P.J.5
Hirose, K.6
-
18
-
-
0034978374
-
Characterization of the efflux transport of 17β-D-17β- glucuronide from the brain across the blood-brain barrier
-
Sugiyama D, Kusuhara H, Shitara Y, Abe T, Meier PJ, Sekine T et al. Characterization of the efflux transport of 17β-D-17β-glucuronide from the brain across the blood-brain barrier. J Pharmacol Exp Ther 2001; 298:316-322.
-
(2001)
J Pharmacol Exp Ther
, vol.298
, pp. 316-322
-
-
Sugiyama, D.1
Kusuhara, H.2
Shitara, Y.3
Abe, T.4
Meier, P.J.5
Sekine, T.6
-
20
-
-
0031459990
-
Interactions of nonsteroidal anti-inflammatory drugs with rat renal organic anion transporter, OAT-K1
-
Masuda S, Saito H, Inui KI. Interactions of nonsteroidal anti-inflammatory drugs with rat renal organic anion transporter, OAT-K1. J Pharmacol Exp Ther 1997; 283:1039-1042.
-
(1997)
J Pharmacol Exp Ther
, vol.283
, pp. 1039-1042
-
-
Masuda, S.1
Saito, H.2
Inui, K.I.3
-
21
-
-
0032943652
-
Cloning and functional characterization of a new multispecific organic anion transporter, OAT-K2, in rat kidney
-
Masuda S, Ibaramoto K, Takeuchi A, Saito H, Hashimoto Y, Inui KI. Cloning and functional characterization of a new multispecific organic anion transporter, OAT-K2, in rat kidney. Mol Pharmacol 1999; 55:743-752.
-
(1999)
Mol Pharmacol
, vol.55
, pp. 743-752
-
-
Masuda, S.1
Ibaramoto, K.2
Takeuchi, A.3
Saito, H.4
Hashimoto, Y.5
Inui, K.I.6
-
22
-
-
0029998349
-
Cell-specific sorting of biogenic amine transporters expressed in epithelial cells
-
Gu HH, Ahn J, Caplan MJ, Blakely RD, Levey AI, Rudnick G. Cell-specific sorting of biogenic amine transporters expressed in epithelial cells. J Biol Chem 1996; 271:18100-18106.
-
(1996)
J Biol Chem
, vol.271
, pp. 18100-18106
-
-
Gu, H.H.1
Ahn, J.2
Caplan, M.J.3
Blakely, R.D.4
Levey, A.I.5
Rudnick, G.6
-
23
-
-
0032692619
-
A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cells
-
Folsch H, Ohno H, Bonifacino JS, Mellman I. A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cells. Cell 1999; 99:189-198.
-
(1999)
Cell
, vol.99
, pp. 189-198
-
-
Folsch, H.1
Ohno, H.2
Bonifacino, J.S.3
Mellman, I.4
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