The EVI-1 gene - its role in pathogenesis of human leukemias

Leukemia Research

Volumn 24, Issue 7, 2000, Pages 553-558

  Jólkowska, Justyna ^a   Witt, Michal ^a  

^a INSTITUTE OF HUMAN GENETICS   (Poland)

Author keywords

3q26; EVI 1; Leukemia; Zn finger protein

Indexed keywords

DNA BINDING PROTEIN; HYBRID PROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

ALTERNATIVE RNA SPLICING; BONE MARROW CELL; CELL TRANSFORMATION; CHROMOSOME 3Q; CHROMOSOME TRANSLOCATION; ECOTROPIC VIRUS; EXON; GENE; GENE EXPRESSION; GENE FUNCTION; GENE INSERTION; GENE LOCATION; GENE STRUCTURE; GENETIC TRANSCRIPTION; HUMAN; LEUKEMIA; MOUSE; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN STRUCTURE; RETROVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW;

EID: 0342859320     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(00)00031-X     Document Type: Article

References (43)

1. Morishita K., Parganas E., Willman C., Whittaker M., Drabkin H., Oval J., Taetle R., Valentine M., Ihle J. Activation of EVI-1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26. Proc. Natl. Acad. Sci USA. 89:1992;3937.
2. Nucifora G. The EVI-1 gene in myeloid leukemia. Leukemia. 11:1997;2022.
3. 128CTCATCTTC. Oncogene. 10:1995;1961.
4. Bartholomew C, Ihle JN. Retroviral insertions 90 kilobases proximal to the EVI-1 myeloid transforming gene activate transcription from the normal promoter. Mol. Cell. Biol. April 1991: 1820.
5. Matsugi T, Morishita K, Ihle J. Identification, nuclear localization and DNA-binding activity of the zinc finger protein encoded by the EVI-1 myeloid transforming gene. Mol. Cell. Biol. Mar. 1990: 1259.
6. Ogawa S., Kurokawa M., Tanaka T., Hangaishi A., Mitani K., Kamada N., Yazaki Y., Hirai H. Increased EVI-1 expression is frequently observed in blast crisis of chronic myelocytic leukemia. Leukemia. 10:1996;788.
7. Russell M., Thompson F., Spier C., Taetle R. Expression of the EVI-1 gene in chronic myelogenous leukemia in blast crisis. Leukemia. 7(10):1993;1654.
8. Suzukawa K., Taki T., Abe T., Asoh H., Kamada N., Yokota J., Morishita K. Identification of translocational breakpoints within the intron region before the last coding exon (exon 12) of the EVI-1 gene in two cases of CML-BC with inv(3)(q21q26). Genomics. 42:1997;356.
9. Morishita K., Parganas E., Douglass E.C., Ihle J. Unique expression of the human EVI-1 gene in an endometrial carcinoma cell line: sequence of cDNAs and structure of alternately spliced transcripts. Oncogene. 5:1990;963.
10. Bartholomew C., Clark A.M. Induction of two alternatively spliced Evi-1 proto-oncogene transcripts by cAMP in kidney cells. Oncogene. 9:1994;939.
11. Perkins AS, Fishel R, Jenkins NA, Copeland NG. Evi-1, a murine zinc finger proto-oncogene, encodes a sequence-specific DNA-binding protein. Mol. Cell. Biol. May 1991: 2665.
12. Xi Z.F., Russell M., Woodward S., Thompson F., Wagner L., Taetle R. Expression of the Zn finger gene, EVI-1, in acute promyelocytic leukemia. Leukemia. 11:1997;212.
13. Funabiki T., Kreider B.L., Ihle J. The carboxyl domain of zinc fingers of the EVI-1 myeloid transforming gene binds a consensus sequence of GAAGATGAG. Oncogene. 9:1994;1575.
14. Bordereaux D., Fichelson S., Tambourin P., Gisselbrecht S. Alternative splicing of the EVI-1 zinc finger gene generates mRNAs which differ by the number of zinc finger motifs. Oncogene. 5:1990;925.
15. Mitani K., Ogawa S., Tanaka T., Miyoshi H., Kurokawa M., Mano H., Yazaki Y., Ohki M., Hirai H. Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26; q22) causes blastic crisis in chronic myelocytic leukemia. EMBO J. 13(3):1994;504.
16. Okada H., Watanabe T., Niki M., Takano H., Chiba N., Yanai N., Tani K., Hibino H., Asano S., Mucenski M.L., Ito Y., Noda T., Satake M. AML1 (-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene. Oncogene. 17:1998;2287.
17. Tanaka T, Mitani K, Kurokawa M, Ogawa S, Tanaka K, Nishida J, Yazaki Y, Shibata Y, Hirai H. Dual functions of the AML1/EVI-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias. Mol. Cell. Biol. May 1995: 2383.
18. Fears S., Mathieu C., Zeleznik-Le N., Huang S., Rowley J.D. Intergenic splicing of MDS1 and EVI-1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family. Proc. Natl. Acad. Sci. USA. 93:1996;1642.
19. Wimmer K., Vinatzer U., Zwirn P., Fonatsch C., Wieser R. Comparative expression analysis of the antagonistic transcription factors Evi-1 and MDS1-Evi1 in murine tissues and during in vitro hematopoietic differentiation. Biochem. Biophys. Res. Commun. 252:1998;691.
20. Soderholm J., Kobayashi H., Mathieu C., Rowley J.D., Nucifora G. The leukemia-associated gene MDS1/EVI-1 is a new type of GATA-binding transactivator. Leukemia. 11:1997;352.
21. n sequences. Oncogene. 11:1995;191.
22. Bartholomew C., Kilbey A., Clark A.M., Walker M. The EVI-1 proto-oncogene encodes a transcriptional repressor activity associated with transformation. Oncogene. 14:1997;569.
23. Pekarsky Y., Rynditch A., Wieser R., Fonatsch C., Gardiner K. Activation of a novel gene in 3q21 and identification of intergenic fusion transcripts with ecotropic viral insertion site I in leukemia. Cancer Res. 57:1997;3914.
24. Ohyashiki K., Ohyashiki J.H., Fujieda H., Shimamoto T., Kawakubo K., Nakazawa S., Suzukawa K., Morishita K., Toyama K. EVI-1 expression associated with a 3q26 anomaly in a leukemia cell line derived from the blast crisis of chronic myeloid leukemia. Leukemia. 8(12):1994;2169.
25. Felischman E.W., Volkova M.A., Fenkel M.A., Konstantinowa L.N., Kulagina O.E., Bavonov A.E., Gordeeva A.A. Translocation (2;3)(p13;q26) in two cases of myeloid malignancies: acute myeloblastic leukemia (M2) and blastic phase of chronic myeloid leukemia. Cancer Genet. Cytogenet. 87:1996;182.
26. Levaltier X., Penther D., Bastard C., Troussard X. T(2;3)(q23;p26) in a patient with AML M2. Br. J. Haematol. 94:1996;1027.
27. Kwong Y.L., Chan L.C., Lie K.W. T(2;3)(p13;q26) in a case of chronic myeloid leukemia. Importance of the involvement of 3q26. Cancer Genet. Cytogenet. 59:1992;95.
28. Desangles F., Vilain E., Arborio M., De Revel T., Flandrin G. T(15;17) hypergranular acute promyelocytic leukemia (M3) developing into a t(3;6) M3 without t(15;17) at relapse. Leuk. Lymphoma. 19:1995;184.
29. Asou H., Suzukawa K., Kita K., Nakase K., Ueda H., Morishita K., Kamada N. Establishment of a undifferentiated leukemia cell line (Kasumi-3) with t(3;7)(q27;q22) and activation of the EVI-1 gene. Jpn. J. Cancer Res. 87:1996;269.
30. Mugneret F., Solary E., Favre B., Caillot D., Sidaner I., Guy H. New case of t(3;17)(q26;q22) as an additional change in a Philadelphia positive chronic myelogenous leukemian acceleration. Cancer Genet. Cytogenet. 60:1992;90.
31. Yu Fu Y., Sadamura S., Ishikura H., Abe Y., Katsuno M., Nishimura J., Nawata H. Expression of EVI-1 and the retinoblastoma genes in acute myelogenous leukemia with t(3;13)(q26;q13-14). Am. J. Hematol. 53:1996;30.
32. Russell M., List A., Greenberg P., Woodward S., Glinsmann B., Parganas E., Ihle J., Taetle R. Expression of EVI-1 in myelodysplastic syndromes and other hematologic malignancies without 3q26 translocations. Blood. 84(4):1994;1243.
33. Privitera E., Longoni D., Brambillasca F., Biondi A. EVI-1 gene expression in myeloid clonogenic cells from juvenile myelomonocytic leukemia (JMML). Leukemia. 11:1997;2045.
34. Morishita K., Parganas E., Parham D.M., Matsugi T., Ihle J.N. The EVI-1 zinc finger myeloid transforming gene is normally expressed in the kidney and in developing oocytes. Oncogene. 5:1990;1419.
35. Hamaguchi H., Suzukawa K., Nagata K., Yamamoto K., Yagasaki F., Morishita K. Establishment of a novel human myeloid leukemia cell line (HNT-34) with t(3;3)(q21;q26), t(9;22)(q34;q11) and the expression of EVI-1 gene, P210 and P190 BCR/ABL chimaeric transcripts from a patient with AML after MDS with 3q21q26 syndrome. Br. J. Haematol. 98:1997;399.
36. Dreyfus F., Bouscary D., Melle J., Ribrag V., Guesnu M., Varet B. Expression of the EVI-1 gene in myelodysplastic syndromes. Leukemia. 9:1995;203.
37. Ohyashiki K., Ohyashiki J.H., Shimamoto T., Toyama K. Pattern of expression and their clinical implications of the GATA family, stem cell leukemia gene, and EVI-1 in leukemia and myelodysplastic syndromes. Leuk. Lymphoma. 23:1996;431.
38. Ogawa S., Kurokawa M., Tanaka T., Mitani K., Inazawa J., Hangaishi A., Tanaka K., Matsuo Y., Minowada J., Tsubota T., Yazaki Y., Hirai H. Structurally altered EVI-1 protein generated in the 3q21q26 syndrome. Oncogene. 13:1996;183.
39. Igarashi T., Shimizu S., Morishita K., Ohtsu T., Itoh K., Minami H., Fujii H., Sasaki Y., Mukai K. Acute myelogenous leukemia with monosomy 7, inv(3)(q21q26), involving activated EVI-1 gene occuring after a complete remission of lymphoblastic lymphoma: a case report. Jpn. J. Clin. Oncol. 28(11):1998;688.
40. Fontenay-Roupie M., Bouscary D., Melle J., Viguie F., Picard F., Guesnu M., Dreyfus F. Expression of the transcription factor EVI-1 in human erythroleukemia cell lines and in leukemias. Hematol. Cell Ther. 39:1997;5.
41. Rath A.V., Schmahl G.E., Niemeyer C.M. Expression of transcription factors during sodium phenylacetate induced erythroid differentiation in K562 cells. Blood Cells Mol. Dis. 23(2):January 31 1997;27.
42. Oval J., Smedsrud M., Taetle R. Expression and regulation of the EVI-1 gene in the human factor-dependent leukemia cell line, UCSD/AML1. Leukemia. 6(5):1992;446.
43. Kilbey A., Bartholomew C. EVI-1 ZF1 DNA binding activity and a second distinct transcriptional repressor region are both required for optimal transformation of Rat1 fibroblast. Oncogene. 16:1998;2287.