The changing role of non-opioid analgesic techniques in the management of postoperative pain

Anesthesia and Analgesia

Volumn 101, Issue 5 SUPPL., 2005, Pages S5-

  White, Paul F ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; AMANTADINE; ANALGESIC AGENT; BUPIVACAINE; CELECOXIB; CLONIDINE; CYCLOOXYGENASE 2 INHIBITOR; DEXMEDETOMIDINE; DEXTROMETHORPHAN; DICLOFENAC; EMLA; GABAPENTIN; IBUPROFEN; INDOMETACIN; KETAMINE; KETOROLAC; LEVOBUPIVACAINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; MAGNESIUM; NAPROXEN; NARCOTIC ANALGESIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PARACETAMOL; PARECOXIB; PROPACETAMOL; ROFECOXIB; ROPIVACAINE; UNINDEXED DRUG; VALDECOXIB;

ADVERSE DRUG REACTION; AGRANULOCYTOSIS; ALLERGIC REACTION; AMBULATORY SURGERY; ANESTHESIST; BLEEDING; BRADYCARDIA; BRONCHOSPASM; CARDIOVASCULAR DISEASE; CONFUSION; CONSTIPATION; DIPLOPIA; DIZZINESS; DRUG DEPENDENCE; DRUG EFFECT; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG TOLERANCE; DRUG USE; EPIDURAL ANESTHESIA; GASTROINTESTINAL HEMORRHAGE; GASTROINTESTINAL SYMPTOM; HEALTH CARE QUALITY; HEART ARRHYTHMIA; HOSPITAL DISCHARGE; HUMAN; HYPERTENSION; ILEUS; INTRINSIC SYMPATHOMIMETIC ACTIVITY; KIDNEY TUBULE DISORDER; LEG EDEMA; LIVER TOXICITY; MUSCLE WEAKNESS; NAUSEA; NYSTAGMUS; PATIENT CONTROLLED ANALGESIA; PERIPHERAL NERVE IRRITATION; PERIPHERAL NEUROPATHY; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PRESCRIPTION; PRIORITY JOURNAL; PRURITUS; PSYCHOMIMETIC REACTION; RASH; RESPIRATION DEPRESSION; REVIEW; SEDATION; SIDE EFFECT; SOMNOLENCE; STEVENS JOHNSON SYNDROME; SURGICAL WOUND BLEEDING; SWEATING; URINARY HESITANCY; URINE RETENTION; VOMITING; WOUND INFECTION;

EID: 27244450884     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ane.0000177099.28914.a7     Document Type: Review

References (280)

1. Kehlet H, Dahl JB. Anaesthesia, surgery and challenges in postoperative recovery. Lancet 2003;362:1921-8.
2. White PF. Ambulatory anesthesia advances into the new millennium. Anesth Analg 2000;90:1234-5.
3. Chung F, Ritchie E, Su J. Postoperative pain in ambulatory surgery. Anesth Analg 1997;85:808-16.
4. White PF. The role of non-opioid analgesic techniques in the management of pain after ambulatory surgery. Anesth Analg 2002;94:577-85.
5. Guignard B, Bossard AE, Coste C, et al. Acute opioid tolerance: intraoperative remifentanil increases postoperative pain and morphine requirement. Anesthesiology 2000;93:409-17.
6. Silvasti M, Svartling N, Pitkanen M, Rosenberg PH. Comparison of intravenous patient-controlled analgesia with tramadol versus morphine after microvascular breast reconstruction. Eur J Anaesthesiol 2000;17:448-55.
7. Rawal N, Allvin R, Amilon A, et al. Postoperative analgesia at home after ambulatory hand surgery: a controlled comparison of tramadol, metamizol, and paracetamol. Anesth Analg 2001;92:347-51.
8. Immer FF, Immer-Bansi AS, Tachesel N, et al. Pain treatment with a COX-2 inhibitor after coronary artery bypass operation: a randomized trial. Ann Thorac Surg 2003;75:490-5.
9. Eriksson H, Tenhunen A, Korttila K. Balanced analgesia improves recovery and outcome after outpatient tubal ligation. Acta Anaesthesiol Scand 1996;40:151-5.
10. Michaloliakou C, Chung F, Sharma S. Preoperative multimodal analgesia facilitates recovery after ambulatory laparoscopic cholecystectomy. Anesth Analg 1996;82:44-51.
11. Pavlin DJ, Horvath KD, Pavlin EG, Sima K. Preincisional treatment to prevent pain after ambulatory hernia surgery. Anesth Analg 2003;97:1627-32.
12. Vloka JD, Hadzic A, Mulcare R, et al. Femoral and genitofemoral nerve blocks versus spinal anesthesia for outpatients undergoing long saphenous vein stripping surgery. Anesth Analg 1997;84:749-52.
13. Sohg D, Greilich NB, White PF, et al. Recovery profiles and costs of anesthesia for outpatient unilateral inguinal herniorrhaphy. Anesth Analg 2000;91:876-81.
14. Li S, Coloma M, White PF, et al. Comparison of the costs and recovery profiles of three anesthetic techniques for ambulatory anorectal surgery. Anesthesiology 2000;93:1225-30.
15. Harrison CA, Morris S, Harvey JS. Effect of ilioinguinal and iliohypogastric nerve block and wound infiltration with 0.5% bupivacaine on postoperative pain after hernia repair. Br J Anaesth 1994;72:691-3.
16. Ding Y, White PF. Post-herniorrhaphy pain in outpatients after pre-incision ilioinguinal-hypogastric nerve block during monitored anesthesia care. Can J Anaesth 1995;42:12-5.
17. Broadman LM, Hannallah RS, Belman AB, et al. Post-circumcision analgesia: a prospective evaluation of subcutaneous ring block of the penis. Anesthesiology 1987;67:399-402.
18. Baram D, Smith C, Stinson S. Intraoperative topical etidocaine for reducing postoperative pain after laparoscopic tubal ligation. J Reprod Med 1990;5:407-10.
19. Gharaibeh KI, Al-Jaberi TM. Bupivacaine instillation into gallbladder bed after laparoscopic cholecystectomy: does it decrease shoulder pain? J Laparoendosc Adv Surg Tech A 2000;10:137-41.
20. Ritchie ED, Tong D, Chung F, et al. Suprascapular nerve block for postoperative pain relief in arthroscopic shoulder surgery: a new modality? Anesth Analg 1997;84:1306-12.
21. Tierney E, Lewis G, Hurtig JB, Johnson D. Femoral nerve block with bupivacaine 0.25 per cent for postoperative analgesia after open knee surgery. Can J Anaesth 1987;34:455-8.
22. Brown AR, Weiss R, Greenberg C, et al. Interscalene block for shoulder arthroscopy: comparison with general anesthesia. Arthroscopy 1993;9:295-300.
23. Casati A, Cappelleri G, Fanelli G, et al. Regional anaesthesia for outpatient knee arthroscopy: a randomized clinical comparison of two different anaesthetic techniques. Acta Anaesthesiol Scand 2000;44:543-7.
24. Woolf Q, Chong MS. Preemptive analgesia: treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg 1993;77:362-79.
25. Ejlersen E, Andersen HB, Eliasen K, Mogensen T. A comparison between preincisional and postincisional lidocaine infiltration and postoperative pain. Anesth Analg 1992;74:495-8.
26. Reuben SS, Bhopatkar S, Maciolek H, et al. The preemptive analgesic effect of rofecoxib after ambulatory arthroscopic knee surgery. Anesth Analg 2002;94:55-9.
27. Moøiniche S, Kehlet H, Dahl JB. A qualitative and quantitative systematic review of preemptive analgesia for postoperative pain relief: the role of timing of analgesia. Anesthesiology 2002;96:725-41.
28. Tverskoy M, Cozacov C, Ayache M, et al. Postoperative pain after inguinal herniorrhaphy with different types of anesthesia. Anesth Analg 1990;70:29-35.
29. Jebeles J, Reilly J, Gutierrez J, et al. The effect of preincisional infiltration of tonsils with bupivacaine on the pain following tonsillectomy under general anesthesia. Pain 1991;47:305-8.
30. O'Neal MG, Beste T, Shackelford DP. Utility of preemptive local analgesia in vaginal hysterectomy. Am J Obstet Gynecol 2003;189:1539-41.
31. Bisgaard T, Klarskov B, Kristiansen VB, et al. Multi-regional local anesthetic infiltration during laparoscopic cholecystectomy in patients receiving prophylactic multimodal analgesia: a randomized, double-blinded, placebo-controlled study. Anesth Analg 1999;89:1017-24.
32. Sarac AM, Aktan AO, Baykan N, et al. The effect of timing of local anesthesia in laparoscopic cholecystectomy. Surg Laparosc Endosc 1996;6:362-6.
33. Hasaniya NW, Zayed FF, Faiz H, Severino R. Preinsertion local anesthesia at the trocar site improves perioperative pain and decreases costs of laparoscopic cholecystectomy. Surg Endosc 2001;15:962-4.
34. Fong SY, Pavy TJ, Yeo ST, et al. Assessment of wound infiltration with bupivacaine in women undergoing day-case gynecological laparoscopy. Reg Anesth Pain Med 2001;26:131-6.
35. Moiniche S, Jorgensen H, Wetterslev J, Dahl JB. Local anesthetic infiltration for postoperative pain relief after laparoscopy: a qualitative and quantitative systematic review of intraperitoneal, port-site infiltration and mesosalpinx block. Anesth Analg 2000;90:899-912.
36. Sinclair R, Cassuto J, Hogstrom S, et al. Topical anesthesia with lidocaine aerosol in the control of postoperative pain. Anesthesiology 1988;68:895-901.
37. Casey WF, Rice LJ, Hannallah RS, et al. A comparison between bupivacaine instillation versus ilioinguinal/iliohypogastric nerve block for postoperative analgesia following inguinal herniorrhaphy in children. Anesthesiology 1990;72:637-9.
38. Tree-Trakarn T, Pirayavaraporn S. Postoperative pain relief for circumcision in children: comparison among morphine, nerve block, and topical analgesia. Anesthesiology 1985;62:519-22.
39. Tree-Trakam T, Pirayavaraporn S, Lertakyamee J. Topical analgesia for relief of post-circumcision pain. Anesthesiology 1987;67:395-9.
40. Choi WY, Irwin MG, Hui TWC, et al. EMLA® cream versus dorsal penile nerve block for postcircumcision analgesia in children. Anesth Analg 2003;96:396-9.
41. Gammaitoni AR, Alvarez NA, Galer BS. Safety and tolerability of the lidocaine patch 5%, a targeted peripheral analgesic: a review of the literature. J Clin Pharmacol 2003;43:111-7.
42. Narchi P, Benhamou D, Fernandez H. Intraperitoneal local anaesthetic for shoulder pain after day-case laparoscopy. Lancet 1991;338:1569-70.
43. Paulson J, Mellinger J, Baguley W. The use of intraperitoneal bupivacaine to decrease the length of stay in elective: laparoscopic cholecystectomy patients. Am J Surg 2003;69:275-8.
44. Rademaker BM, Kalkman CJ, Odoom JA, et al. Intraperitoneal local anaesthetics after laparoscopic cholecystectomy: effects on postoperative pain, metabolic responses and lung function. Br J Anaesth 1994;72:263-6.
45. Joris J, Thiry E, Paris P, et al. Pain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine. Anesth Analg 1995;81:379-84.
46. Scheinin B, Kellokumpu I, Lindgren I, et al. Effect of intraperitoneal bupivacaine on pain after laparoscopic cholecystectomy. Acta Anaesthesiol Scand 1995;9:195-8.
47. Raetzell M, Maier C, Schroder D, Wulf H. Intraperitoneal application of bupivacaine during laparoscopic cholecystectomy: risk or benefit? Anesth Analg 1995;81:967-72.
48. Pasqualucci A, de Angelis V, Contardo R, et al. Preemptive analgesia: intraperitoneal local anesthetic in laparoscopic cholecystectomy: a randomized, double-blind, placebo-controlled study. Anesthesiology 1996;85:11-20.
49. Szem JW, Hydo L, Barie PS. A double-blinded evaluation of intraperitoneal bupivacaine vs saline for the reduction of postoperative pain and nausea after laparoscopic cholecystectomy. Surg Endosc 1996;10:44-8.
50. Mraovic B, Jurisic T, Kogler-Majeric V, Sustic A. Intraperitoneal bupivacaine for analgesia after laparoscopic cholecystectomy. Acta Anaesthesiol Scand 1997;41:193-6.
51. Cunniffe MG, McAnena OJ, Dar JA, et al. A prospective randomized trial of intraoperative bupivacaine irrigation for management of shoulder-tip pain following laparoscopy. Am J Surg 1998;176:258-61.
52. Wallin G, Cassuto J, Hogstrom S, Hedner T. Influence of intraperitoneal anesthesia on pain and the sympathoadrenal response to abdominal surgery. Acta Anaesthesiol Scand 1988;32:553-8.
53. Zmora O, Stolik-Dollberg O, Bar-Zakai B, et al. Intraperitoneal bupivacaine does not attenuate pain following laparoscopic cholecystectomy. JSLS 2000;4:301-4.
54. Maestroni U, Sortini D, Devito C, et al. A new method of preemptive analgesia in laparoscopic cholecystectomy. Surg Endosc 2002;16:1336-40.
55. Saff GN, Marks RA, Kuroda M, et al. Analgesic effect of bupivacaine on extraperitoneal laparoscopic hernia repair. Anesth Analg 1998;87:377-81.
56. Ashcraft EE, Baillie GM, Shafizadeh SF, et al. Further improvements in laparoscopic donor nephrectomy: decreased pain and accelerated recovery. Clin Transplant 2001;15:59-61.
57. Yndgaard S, Holst P, Bjerre-Jepsen K, et al. Subcutaneously versus subfascially administered lidocaine in pain treatment after inguinal herniotomy. Anesth Analg 1994;79:324-7.
58. Scott NB, Mogensen T, Bigler D, Kehlet H. Comparison of the effects of continuous intrapleural vs epidural administration of 0.5% bupivacaine on pain, metabolic response and pulmonary function following cholecystectomy. Acta Anaesthesiol Scand 1989;33:535-9.
59. Schroeder D, Baker P. Interpleural catheter for analgesia after cholecystectomy: the surgical perspective. Aust N Z J Surg 1990;60:689-94.
60. Frank ED, McKay W, Rocco A, Gallo JP. Lnterpleural bupivacaine for postoperative analgesia following cholecystectomy: a randomized prospective study. Reg Anesth 1990;15:26-30.
61. Stromskag KE, Minor BG, Lindeberg A. Comparison of 40 milliliters of 0.25% intrapleural bupivacaine with epinephrine with 20 milliliters of 0.5% intrapleural bupivacaine with epinephrine after cholecystectomy. Anesth Analg 1991;73:397-400.
62. Rademaker BM, Sih IL, Kalkman CJ, et al. Effects of interpleurally administered bupivacaine 0.5% on opioid analgesic requirements and endocrine response during and after cholecystectomy: a randomized double-blind controlled study. Acta Anaesthesiol Scand 1991;35:108-12.
63. Laurito CE, Kirz LI, VadeBoncouere TR, et al. Continuous infusion of interpleural bupivacaine maintains effective analgesia after cholecystectomy. Anesth Analg 1991;72:516-21.
64. Frenette L, Boudreault D, Guay J. Interpleural analgesia improves pulmonary function after cholecystectomy. Can J Anaesth 1991;38:71-4.
65. Oxorn DC, Whatley GS. Post-cholecystectomy pulmonary function following interpleural bupivacaine and intramuscular pethidine. Anaesth Intensive Care 1989;17:440-3.
66. Lee A, Boon D, Bagshaw P, Kempthorne P. A randomized double-blind study of interpleural analgesia after cholecystectomy. Anaesthesia 1990;45:1028-31.
67. Schulte-Steinberg H, Weninger E, Jokisch D, et al. Intraperitoneal versus interpleural morphine or bupivacaine for pain after laparoscopic cholecystectomy. Anesthesiology 1995;82:634-40.
68. Ross WB, Tweedie JH, Leong YP, et al. Intercostal blockade and pulmonary function after cholecystectomy. Surgery 1989;105:166-9.
69. Dahl MR, Dasta JF, Zuelzer W, McSweeney TD. Lidocaine local anesthesia for arthroscopic knee surgery. Anesth Analg 1990;71:670-4.
70. Smith I, Van Hemelrijck J, White PF, Shively R. Effects of local anesthesia on recovery after outpatient arthroscopy. Anesth Analg 1991;73:536-9.
71. Smith I, Shively RA, White PF. Effects of ketorolac and bupivacaine on recovery after outpatient arthroscopy. Anesth Analg 1992;75:208-12.
72. Stein C, Comisel K, Haimerl E, et al. Analgesic effect of intraarticular morphine after arthroscopic knee surgery. N Engl J Med 1991;325:1123-6.
73. Reuben S, Connelly NR. Postoperative analgesia for outpatient arthroscopic knee surgery with intraarticular bupivacaine and ketorolac. Anesth Analg 1995;80:1154-7.
74. Wang JJ, Ho ST, Lee SC, et al. Intraarticular triamcinolone acetonide for pain control after arthroscopic knee surgery. Anesth Analg 1998;87:1113-6.
75. Joshi W, Reuben SS, Kilaru PR, et al. Postoperative analgesia for outpatient arthroscopic knee surgery with intraarticular clonidine and/or morphine. Anesth Analg 2000;90:1102-6.
76. Khoury GF, Chen ACN, Garland DE, Stein C. Intraarticular morphine, bupivacaine, and morphine/bupivacaine for pain control after knee videoarthroscopy. Anesthesiology 1992;77:263-6.
77. Reuben SS, Sklar J, El-Mansouri M. The preemptive analgesic effect of intraarticular bupivacaine and morphine after ambulatory arthroscopic knee surgery. Anesth Analg 2001;92:923-6.
78. Thomas DFM, Lambert WG, Williams KL. The direct perfusion of surgical wounds with local anaesthetic solution: an approach to postoperative pain? Ann R Coll Surg Engl 1983;65:226-9.
79. Gibbs P, Purushotam A, AuId C, Cuschieri RJ. Continuous wound perfusion with bupivacaine for postoperative wound pain. Br J Surg 1988;75:923-4.
80. Levack ID, Holmes JD, Robertson GS. Abdominal wound perfusion for the relief of postoperative pain. Br J Anaesth 1986;58:615-9.
81. Gupta A, Thorn SE, Axelsson K, et al. Postoperative pain relief using intermittent injections of 0.5% ropivacaine through a catheter after laparoscopic cholecystectomy. Anesth Analg 2002;95:450-6.
82. White PF, Rawal S, Latham P, et al. Use of a continuous local anesthetic infusion for pain management after median sternotomy. Anesthesiology 2003;99:918-23.
83. Bianconi M, Ferraro L, Ricci R, et al. The pharmacokinetics and efficacy of ropivacaine continuous wound instillation after spine fusion surgery. Anesth Analg 2004;98:166-72.
84. Rawal N, Axelsson K, Hylander J, et al. Postoperative patient-controlled local anesthetic administration at home. Anesth Analg 1998;86:86-9.
85. Rawal N, Allvin R, Axelsson K, et al. Patient-controlled regional analgesia (PCRA) at home: controlled comparison between bupivacaine and ropivacaine brachial plexus analgesia. Anesthesiology 2002;96:1290-6.
86. Fredman B, Shapiro A, Zohar E, et al. The analgesic efficacy of patient-controlled ropivacaine instillation after Cesarean delivery. Anesth Analg 2000;91:1436-40.
87. Fredman B, Zohar E, Tarabykin A, et al. Bupivacaine wound instillation via an electronic patient-controlled analgesia device and a double-catheter system does not decrease postoperative pain or opioid requirements after major abdominal surgery. Anesth Analg 2001;92:189-93.
88. Cameron AEP, Cross FW. Pain and morbility after inguinal herniorrhaphy: ineffectiveness of subcutaneous bupivacaine. Br J Surg 1985;72:68-9.
89. Ilfeld BM, Morey TE, Wang RD, Enneking FK. Continuous popliteal sciatic nerve block for postoperative pain control at home: a randomized, double-blinded, placebo-controlled study. Anesthesiology 2002;97:959-65.
90. White PF, Issioui T, Skrivanek GD, et al. Use of a continuous popliteal sciatic nerve block for the management of pain after major podiatric surgery: does it improve quality of recovery? Anesth Analg 2003;97:1303-9.
91. Ilfeld BM, Morey TE, Enneking FK. Continuous infraclavicular brachial plexus block for postoperative pain control at home: a randomized, double-blinded, placebo-controlled study. Anesthesiology 2002;96:1297-304.
92. Singelyn FJ, Seguy S, Gouverneur JM. Interscalene brachial plexus analgesia after open shoulder surgery: continuous versus patient-controlled infusion. Anesth Analg 1999;89:1216-20.
93. Singelyn FJ, Vanderelst PE, Gouverneus JM. Extended femoral nerve sheath block after total hip arthroplasty: continuous versus patient-controlled techniques. Anesth Analg 2001;92:455-9.
94. Ilfeld BM, Morey TE, Enneking FK. Portable infusion pumps used for continuous regional analgesia: delivery rate accuracy and consistency. Reg Anesth Pain Med 2003;28:424-32.
95. Capdevila X, Macaire P, Aknin P, et al. Patient-controlled perineural analgesia after ambulatory orthopedic surgery: a comparison of electronic versus elastomeric pumps. Anesth Analg 2003;96:414-7.
96. Cuvillon P, Ripart J, Lalourcey L, et al. The continuous femoral nerve block catheter for postoperative analgesia: bacterial colonization, infectious rate and adverse effects. Anesth Analg 2001;93:1045-9.
97. Ilfeld BM, Esener DE, Morey TE, Enneking FK. Ambulatory perineural infusion: the patient's perspective. Reg Anesth Pain Med 2003;28:418-23.
98. Kehlet H, Dahl JB. The value of "multimodal" or "balanced analgesia" in postoperative pain treatment. Anesth Analg 1993;77:1048-56.
99. Klein SM, Greengrass RA, Steele SM, et al. A comparison of 0.5% bupivacaine, 0.5% ropivacaine, and 0.75% ropivacaine for interscalene brachial plexus block. Anesth Analg 1998;87:1316-9.
100. Mulroy MF, Larkin KL, Batra MS, et al. Femoral nerve block with 0.25% or 0.5% bupivacaine improves postoperative analgesia following outpatient arthroscopic anterior cruciate ligament repair. Reg Anesth Pain Med 2001;26:24-9.
101. Casati A, Vinciguerra F, Scarioni M, et al. Lidocaine versus ropivacaine for continuous interscalene brachial plexus block after open shoulder surgery. Acta Anaesthesiol Scand 2003;47:355-60.
102. Casati A, Magistris L, Fanelli G, et al. Small-dose clonidine prolongs postoperative analgesia after sciatic-femoral nerve block with 0.75% ropivacaine for foot surgery. Anesth Analg 2000;91:388-92.
103. Niemi G, Breivik H. Epinephrine markedly improves thoracic epidural analgesia produced by a small-dose infusion of ropivacaine, fentanyl, and epinephrine after major thoracic or abdominal surgery: a randomized, double-blinded crossover study with and without epinephrine. Anesth Analg 2002;94:1598-605.
104. Ilfeld BM, Morey TE, Enneking FK. Continuous infraclavicular perineural infusion with clonidine and ropivacaine compared with ropivacaine alone: a randomized, double-blinded, controlled study. Anesth Analg 2003;97:706-12.
105. Klin SM, Greengrass RA, Grant SA, et al. Ambulatory surgery for multi-ligament knee reconstruction with continuous dual catheter peripheral nerve blockade. Can J Anaesth 2001;48:375-8.
106. Klein SM, Grant SA, Greengrass RA, et al. Interscalene brachial plexus block with a continuous catheter system and a disposable infusion pump. Anesth Analg 2000;91:1473-8.
107. Ilfeld BM, Morey TE, Wright TW, et al. Continuous interscalene brachial plexus block for postoperative pain control at home: a randomized, double-blinded, placebo-controlled study. Anesth Analg 2003;96:1089-95.
108. Yee JP, Koshiver JE, Allbon C, Brown CR. Comparison of intramuscular ketorolac tromethamine and morphine sulphate for analgesia of pain after major surgery. Pharmacotherapy 1986;6:253-61.
109. O'Hara DA, Fragen RJ, Kinzer M, Pemberton D. Ketorolac tromethamine as compared with morphine sulfate for the treatment of postoperative pain. Clin Pharmacol Ther 1987;41:556-61.
110. Powell H, Smallman JMB, Morgan M. Comparison of intramuscular ketorolac and morphine in pain control after laparotomy. Anaesthesia 1990;45:538-42.
111. Murray AW, Brockway MS, Kenny GNC. Comparison of the cardiorespiratory effects of ketorolac and alfentanil during propofol anaesthesia. Br J Anaesth 1989;63:601-3.
112. Ding Y, White PF. Comparative effects of ketorolac, dezocine and fentanyl as adjuvants during outpatient anesthesia. Anesth Analg 1992;75:566-71.
113. Ramirez-Ruiz M, Smith I, White PF. Use of analgesics during propofol sedation: a comparison of ketorolac, dezocine, and fentanyl. J Clin Anesth 1995;7:481-5.
114. Wong HY, Carpenter RL, Kopacz DJ, et al. A randomized double-blind evaluation of ketorolac tromethamine for postoperative analgesia in ambulatory surgery patients. Anesthesiology 1993;78:6-14.
115. Singh H, Bossard RF, White PF, Yeatts RW. Effects of ketorolac versus bupivacaine coadministration during patient-controlled hydromorphone epidural analgesia after thoracotomy procedures. Anesth Analg 1997;84:564-9.
116. Coloma M, White PF, Huber PJ, et al. The effect of ketorolac on recovery after anorectal surgery: IV versus local administration. Anesth Analg 2000;90:1107-10.
117. Romsing J, Moiniche S, Ostergaard D, Dahl JB. Local infiltration with NSAIDs for postoperative analgesia: evidence for a peripheral analgesic action. Acta Anaesthesiol Scand 2000;44:672-83.
118. Ding Y, Fredman B, White PF. Use of ketorolac and fentanyl during outpatient gynecological surgery. Anesth Analg 1993;77:205-10.
119. Liu J, Ding Y, White PF, et al. Effects of ketorolac on postoperative analgesia and ventilatory function after laparoscopic cholecystectomy. Anesth Analg 1993;76:1061-6.
120. Fredman B, Jedeikin R, Olsfanger D, Aronheim M. The opioid-sparing effect of diclofenac sodium in outpatient extracorporeal shock wave lithotripsy (ESWL). J Clin Anesth 1993;5:141-4.
121. McLoughlin C, McKinney MS, Fee JPH, Boules Z. Diclofenac for day-care arthroscopy surgery: comparison with standard opioid therapy. Br J Anaesth 1990;65:620-3.
122. Gillberg LE, Harsten AS, Stahl LB. Preoperative diclofenac sodium reduces post-laparoscopy pain. Can J Anaesth 1993;40:406-8.
123. Varrassi G, Panella L, Piroli A, et al. The effects of perioperative ketorolac infusion on postoperative pain and endocrine-metabolic response. Anesth Analg 1994;78:514-9.
124. Zackova M, Taddei S, Calo P, et al. Ketorolac vs tramadol in the treatment of postoperative pain during maxillofacial surgery. Minerva Anesthesiol 2001;67:641-6.
125. Wilson YG, Rhodes M, Ahmed R, et al. Intramuscular diclofenac sodium postoperative analgesia after laparoscopic cholecystectomy: A randomized, controlled trial. Surg Laparosc Endosc 1994;4:340-4.
126. Fredman B, Olsfanger D, Jedeikin R. A comparative study of ketorolac and diclofenac on post-laparoscopic cholecystectomy pain. Eur J Anaesthesiol 1995;12:501-4.
127. Baer GA, Rorarius MGF, Kolehmainen S, Seliu S. The effect of paracetamol or diclofenac administered before operation on postoperative pain and behavior after adenoidectomy in small children. Anaesthesia 1992;47:1078-80.
128. Watcha MF, Ramirez-Ruiz M, White PF, et al. Perioperative effects of oral ketorolac and acetaminophen in children undergoing bilateral myringotomy. Can J Anaesth 1992;39:649-54.
129. Splinter WM, Reid CW, Roberts DJ, Bass J. Reducing pain after inguinal hernia repair in children: caudal anesthesia versus ketorolac tromethamine. Anesthesiology 1997;87:542-6.
130. Watcha MF, Jones MB, Lagueruela RG, et al. Comparison of ketorolac and morphine as adjuvants during pediatric surgery. Anesthesiology 1992;76:368-72.
131. Maunuksela EL, Kokki H, Bullingham RES. Comparison of IV ketorolac with morphine for postoperative pain in children. Clin Pharmacol Ther 1992;52:436-43.
132. Forse A, El-Beheiry H, Butler PO, Pace RF. Indomethacin and ketorolac given preoperatively are equally effective in reducing early postoperative pain after laparoscopic cholecystectomy. Can J Surg 1996;39:26-30.
133. Comfort VK, Code WE, Rooney ME, Yip RW. Naproxen premedication reduces postoperative tubal ligation pain. Can J Anaesth 1992;4:349-52.
134. Rosenblum M, Weller RS, Conard PL, et al. Ibuprofen provides longer lasting analgesia than fentanyl after laparoscopic surgery. Anesth Analg 1991;73:255-9.
135. Doyle G, Jayawardena S, Ashraf E, Cooper SA. Efficacy and tolerability of nonprescription ibuprofen versus celecoxib for dental pain. J Clin Pharmacol 2002;42:912-9.
136. Pickering AE, Bridge HS, Nolan J, Stoddart PA. Double-blind, placebo-controlled analgesic study of ibuprofen or rofecoxib in combination with paracetamol for tonsillectomy in children. Br J Anaesth 2002;88:72-7.
137. Raeder JC, Steine S, Vatsgar TT. Oral ibuprofen versus paracetamol plus codeine for analgesia after ambulatory surgery. Anesth Analg 2001;92:1470-2.
138. Edwards JE, McQuay HJ, Moore RA. Combination analgesic efficacy: Individual patient data meta-analysis of single-dose oral tramadol plus acetaminophen in acute postoperative pain. J Pain Symptom Manage 2002;23:121-30.
139. Souter A, Fredman B, White PF. Controversies in the perioperative use of nonsteroidal antiinflammatory drugs. Anesth Analg 1994;79:1178-90.
140. Rusy LM, Houck CS, Sullivan LJ, et al. A double-blind evaluation of ketorolac tromethamine versus acetaminophen in pediatric tonsillectomy: analgesia and bleeding. Anesth Analg 1995;80:226-9.
141. Gunter JB, Varughese AM, Harrington JF, et al. Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine. Anesth Analg 1995;81:1136-41.
142. Moiniche S, Romsing J, Dahl JB, Tramer MR. Nonsteroidal antiinflammatory drugs and the risk of operative bleeding after tonsillectomy: a quantitative systematic review. Anesth Analg 2003;96:68-77.
143. FitzGerald GA, Patrono C. The coxibs, selective inhibitors of cyclooxygenase-2. N Engl J Med 2001;345:433-42.
144. Reuben SS, Connelly NR. Postoperative analgesic effects of celecoxib or rofecoxib after spinal fusion surgery. Anesth Analg 2000;91:1221-5.
145. Issioui T, Klein KW, White PF, et al. The efficacy of premedication with celecoxib and acetaminophen in preventing pain after otolaryngologic surgery. Anesth Analg 2002;94:1188-93.
146. Recart A, Issioui T, White PF, et al. The efficacy of celecoxib premedication on postoperative pain and recovery times after ambulatory surgery: a dose-ranging study. Anesth Analg 2003;96:1631-5.
147. Issioui T, Klein KW, White PF, et al. Cost-efficacy of rofecoxib versus acetaminophen for preventing pain after ambulatory surgery. Anesthesiology 2002;97:931-7.
148. Ma H, Tang J, White PF, et al. Perioperative rofecoxib improves early recovery after outpatient herniorrhaphy. Anesth Analg 2004;98:970-5.
149. Watcha MF, Issioui T, Klein KW, White PF. Costs and effectiveness of rofecoxib, celecoxib and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. Anesth Analg 2003;96:987-94.
150. Sinatra RS, Shen QJ, Halaszynski T, et al. Preoperative rofecoxib oral suspension as an analgesic adjunct after lower abdominal surgery: the effects on effort-dependent pain and pulmonary function. Anesth Analg 2004;98:135-40.
151. Buvanendran A, Kroin JS, Tuman KJ, et al. Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial. JAMA 2003;290:2411-8.
152. Desjardins PJ, Shu VS, Recker DP, et al. A single preoperative oral dose of valdecoxib, a new cyclooxygenase-2 specific inhibitor, relieves post-oral surgery or bunionectomy pain. Anesthesiology 2002;97:565-73.
153. Joshi GP, Viscusi ER, Gan TJ, et al. Effective treatment of laparoscopic cholecystectomy pain with intravenous followed by oral COX-2 specific inhibitor. Anesth Analg 2004;98:336-42.
154. Fricke J, Varkalis J, Zwillich S, et al. Valdecoxib is more efficacious than rofecoxib in relieving pain associated with oral surgery. Am J Ther 2002;9:89-97.
155. Desjardins PJ, Grossman EH, Kuss ME, et al. The injectable cyclooxygenase-2-specific inhibitor parecoxib sodium has analgesic efficacy when administered preoperatively. Anesth Analg 2001;93:721-7.
156. Tang J, Li S, White PF, et al. Effect of parecoxib, a novel intravenous cyclooxygenase-2 inhibitor, on the postoperative opioid requirement and quality of pain control. Anesthesiology 2002;96:1305-9.
157. Ng A, Smith G, Davidson AC. Analgesic effects of parecoxib following total abdominal hysterectomy. Br J Anaesth 2003;90:746-9.
158. Mehlisch DR, Desjardins PJ, Daniels S, Hubbard RC. Single doses of parecoxib sodium intravenously are as effective as ketorolac in reducing pain after oral surgery. J Oral Maxillofac Surg 2003;61:1030-7.
159. Barton SF, Langeland FF, Snabes MC, et al. Efficacy and safety of intravenous parecoxib sodium in relieving acute postoperative pain following gynecologic laparotomy surgery. Anesthesiology 2002;97:306-14.
160. Malan TP Jr., Marsh G, Hakki SI, et al. Parecoxib sodium, a parenteral cyclooxygenase 2 selective inhibitor, improves morphine analgesia and is opioid-sparing following total hip arthroplasty. Anesthesiology 2003;98:950-6.
161. Ott E, Nussmeier NA, Duke PC, et al. Efficacy and safety of cyclooxygenase 2 inhibitors parecoxib and valdecoxib in patients undergoing coronary artery bypass surgery. J Thorac Cardiovasc Surg 2003;125:1481-92.
162. Malmstrom K, Kotey P, Coughlin H, Desjardins PJ. A randomized, double-blind, parallel-group study comparing the analgesic effect of etoricoxib to placebo, naproxen sodium, and acetaminophen with codeine using the dental impaction pain model. Clin J Pain 2004;20:147-55.
163. Romsing J, Moiniche S. A systematic review of COX-2 inhibitors compared with traditional NSAIDs, or different COX-2 inhibitors for postoperative pain. Acta Anaesthesiol Scand 2004;48:525-46.
164. Stichtenoth DO, Frolich JC. The second generation of COX-2 inhibitors: what advantages do the newest offer? Drugs 2003;63:33-45.
165. Glassman SD, Rose S, Matthew BE, et al. The effect of postoperative nonsteroidal antiinflammatory drug administration on spinal fusion. Spine 1998;23:834-8.
166. Einhorn TA. COX-2: Where are we in 2003? The role of cyclooxygenase-2 in bone repair. Arthritis Res Ther 2003;5:5-7.
167. Seidenberg AB, An YH. Is there an inhibitory effect of COX-2 inhibitors on bone healing? Pharm Res 2004;50:151-6.
168. Simon AM, Manigrasso MB, O'Connor JP. Cyclo-oxygenase 2 function is essential for bone fracture healing. J Bone Miner Res 2002;17:963-76.
169. Harder AT, An YH. The mechanisms of the inhibitory effects of nonsteroidal antiinflammatory drugs on bone healing: a concise review. J Clin Pharm 2004;43:807-15.
170. Gajraj NM. Cyclooxygenase-2 inhibitors. Anesth Analg 2003;96:1720-38.
171. Gilron I, Milne B, Hong M. Cyclooxygenase-2 inhibitors in postoperative pain management. Anesthesiology 2003;99:1198-208.
172. Cicconetti A, Bartoli A, Ripari F, Ripari A. COX-2 selective inhibitors: a literature review of analgesic efficacy and safety in oral-maxillofacial surgery. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;97:139-46.
173. Hyllested M, Jones S, Pedersen JL, Kehlet H. Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review. Br J Anaesth 2002;88:199-214.
174. Schug SA, Sidebotham DA, McGuinnety M, et al. Acetaminophen as an adjunct to morphine by patient-controlled analgesia in the management of acute postoperative pain. Anesth Analg 1998;87:368-72.
175. Korpela R, Korvenoja P, Meretoja OA. Morphine-sparing effect of acetaminophen in pediatric day-case surgery. Anesthesiology 1999;91:442-7.
176. Birmingham PK, Tobin MJ, Fisher DM, et al. Initial and subsequent dosing of rectal acetaminophen in children: a 24-hour pharmacokinetic study of new dose recommendations. Anesthesiology 2001;94:385-9.
177. Varrassi G, Marinangeli F, Agro F, et al. A double-blinded evaluation of propacetamol versus ketorolac in combination with patient-controlled analgesia morphine: analgesic efficacy and tollerability after gynecologic surgery. Anesth Analg 1999;88:611-16.
178. Zhou TJ, Tang J, White PF. Propacetamol versus ketorolac for treatment of acute postoperative pain after total hip or knee replacement. Anesth Analg 2001;92:1569-75.
179. Delbos A, Boccard E. The morphine-sparing effect of propacetamol in
180. Hernandez-Palazon J, Tortosa JA, Martinez-Lage JF, Perez-Flores D. Intravenous administration of propacetamol reduces morphine consumption alter spinal fusion surgery. Anesth Analg 2001;92:1473-6.
181. Lahtinen P, Kokki H, Hendolin H, et al. Propacetamol as adjunctive treatment for postoperative pain after cardiac surgery. Anesth Analg 2002;95:813-9.
182. Moller PL, Juhl GI, Payen-Champenois C, et al. Ready-to-use IV paracetamol: comparable analgesic efficacy, but better local safety than its prodrug, propacetamol for postoperative pain after third molar surgery. Anesth Analg 2005;101:90-6.
183. Coloma M, Chiu JW, White PF, Armbruster SC. The use of esmolol as an alternative to remifentanil during desflurane anesthesia for fast-track outpatient gynecologic laparoscopic surgery. Anesth Analg 2001;92:352-7.
184. Hillis WS. Areas of emerging interest in analgesia: cardiovascular complications. Am J ther 2002;9:259-69.
185. Badrinath S, Avramov WL, Trevor AJ. Ketamine: its pharmacology and therapeutic uses. Anesthesiology 1982;56:119-36.
186. Badrinath S, Avramov MN, Shadrick M, et al. The use of ketamine-propofol combination during monitored anesthesia care. Anesth Analg 2000;90:858-62.
187. Mortero RF, Clark LD, Tolan MM, et al. The effects of small-dose ketamine on propofol sedation: respiration, postoperative mood, perception, cognition, and pain. Anesth Analg 2001;92:1465-9.
188. Kohr R, Durieux ME. Ketamine: teaching an old drug new tricks. Anesth Analg 1998;87:1186-93.
189. Blakeley KR, Klein KW, White PF, et al. A total IV anesthetic technique for outpatient facial laser resurfacing. Anesth Analg 1998;87:827-9.
190. Guillou N, Tanguy M, Seguin P, et al. The effects of small-dose ketamine on morphine consumption in surgical intensive care unit patients after major abdominal surgery. Anesth Analg 2003;97:843-7.
191. Reeves M, Lindholm DE, Myles PS, et al. Adding ketamine to morphine for patient-controlled analgesia after major abdominal surgery: a double-blinded, randomized controlled trial. Anesth Analg 2001;93:116-20.
192. Sveticic G, Gentilini A, Eichenberger U, et al. Combinations of morphine with ketamine for patient-controlled analgesia: a new optimization method. Anesthesiology 2003;98:1195-205.
193. Suzuki M, Tsueda K, Lansing PS, et al. Small-dose ketamine enhances morphine-induced analgesia after outpatient surgery. Anesth Analg 1999;89:98-103.
194. Menigaux C, Fletcher D, Dupont X, et al. The benefits of intraoperative small-dose ketamine on postoperative pain after anterior cruciate ligament repair. Anesth Analg 2000;90:129-35.
195. Menigaux C, Guignard B, Fletcher D, et al. Intraoperative small-dose ketamine enhances analgesia after outpatient knee arthroscopy. Anesth Analg 2001;93:606-12.
196. Guignard B, Coste C, Costes H, et al. Supplementing desflurane- remifentanil anesthesia with small-dose ketamine reduces perioperative opioid analgesic requirements. Anesth Analg 2002;95:103-8.
197. Guillou N, Tanguy M, Seguin P, et al. The effects of small-dose ketamine on morphine consumption in surgical intensive care unit patients after major abdominal surgery. Anesth Analg 2003;97:843-7.
198. Elhakim M, Khalafallah Z, El-Fattah HA, et al. Ketamine reduces swallowing-evoked pain after paediatric tonsillectomy. Acta Anaesthesiol Scand 2003;47:604-9.
199. Taura P, Fuster J, Blasi A, et al. Postoperative pain relief after hepatic resection in cirrhotic patients: the efficacy of a single small dose of ketamine plus morphine epidurally. Anesth Analg 2003;96:475-80.
200. Fu ES, Miguel R, Scharf JE. Preemptive ketamine decreases postoperative narcotic requirements in patients undergoing abdominal surgery. Anesth Analg 1997;84:1086-90.
201. Adam F, Libier M, Oszustowicz T, et al. Preoperative-small-dose ketamine has no preemptive analgesic effect in patients undergoing total mastectomy. Anesth Analg 1999;89:444-7.
202. Dahl V, Ernoe PE, Steen T, et al. Does ketamine have preemptive effects in women undergoing abdominal hysterectomy procedures? Anesth Analg 2000;90:1419-22.
203. Weinbroum AA. A single small dose of postoperative ketamine provides rapid and sustained improvement in morphine analgesia in the presence of morphine-resistant pain. Anesth Analg 2003;96:789-95.
204. Laulin JP, Maurette P, Corcuff JB, et al. The role of ketamine in preventing fentanyl-induced hyperalgesia and subsequent acute morphine tolerance. Anesth Analg 2002;94:1263-9.
205. Jaksch W, Lang S, Reichhalter R, et al. Perioperative small-dose S(+)-ketamine has no incremental beneficial effects on postoperative pain when standard-practice opioid infusions are used. Anesth Analg 2002;94:981-6.
206. Himmelseher S, Ziegler-Pithamitsis D, Argiriadou H, et al. Small-dose S(+)-ketamine reduces postoperative pain when applied with ropivacaine in epidural anesthesia for total knee arthroplasty. Anesth Analg 2001;92:1290-5.
207. Lauretti GR, Oliveira AP, Rodrigues AM, Paccola CA. The effect of transdermal nitroglycerin on spinal S(+)-ketamine antinociception following orthopedic surgery. J Clin Anesth 2001;13:576-81.
208. White PF, Ham J, Way WL, Trevor AJ. Pharmacology of ketamine isomers in surgical patients. Anesthesiology. 1980;52:231-9.
209. Mathisen LC, Aasbo V, Raeder J. Lack of preemptive analgesic effect of (R)-ketamine in laparoscopic cholecystectomy. Acta Anaesthesiol Scand 1999;43:220-4.
210. Ilkjaer S, Bach LF, Nielsen PA, et al. Effect of preoperative oral dextromethorphan on immediate and late postoperative pain and hyperalgesia after total abdominal hysterectomy. Pain 2000;86:19-24.
211. Weinbroum AA, Gorodezky A, Niv D, et al. Dextromethorphan attenuation of postoperative pain and primary and secondary thermal hyperalgesia. Can J Anaesth 2001;48:167-74.
212. Wu CT, Yu JC, Yeh CC, et al. Preincisional dextromethorphan treatment decreases postoperative pain and opioid requirement after laparoscopic cholecystectomy. Anesth Analg 1999;88:1331-4.
213. Helmy SA, Bali A. The effect of the preemptive use of the NMDA receptor antagonist dextromethorphan on postoperative analgesic requirements. Anesth Analg 2001;92:739-44.
214. Wu CT, Yu JC, Yeh CC, et al. Postoperative intramuscular dextromethorphan injection provides pain relief and decreases opioid requirement after modified radical mastectomy. Int J Surg Invest 2000;2:145-9.
215. Wadhwa A, Clarke D, Goodchild CS, Young D. Large-dose oral dextromethorphan as an adjunct to patient-controlled analgesia with morphine after knee surgery. Anesth Analg 2001;92:448-54.
216. Ilkjaer S, Nielsen PA, Bach LF, et al. The effect of dextromethorphan, alone or in combination with ibuprofen, on postoperative pain after minor gynaecological surgery. Acta Anaesthesiol Scand 2000;44:873-7.
217. Yeh CC, Hot ST, Kong SS, et al. Absence of preemptive analgesic effect of dextromethorphan in total knee replacement under epidural anesthesia. Acta Anaesthesiol Sin 2000;38:187-93.
218. Gottschalk A, Schroeder F, Ufer M, et al. Amantadine, a N-methyl-D-aspartate receptor antagonist, does not enhance postoperative analgesia in women undergoing abdominal hysterectomy. Anesth Analg 2001;93:192-6.
219. Snijdelaar DG, Koren G, Katz J. Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy. Anesthesiology 2004;100:134-41.
220. Segal IS, Jarvis DJ, Duncan SR, et al. Clinical efficacy of oral-transdermal clonidine combinations during the perioperative period. Anesthesiology 1991;74:220-5.
221. Singh H, Liu J, Gaines GY, White PF. Effect of oral clonidine and intrathecal fentanyl on tetracaine spinal block. Anesth Analg 1994;79:1113-6.
222. Milligan KR, Convery PN, Weir P, et al. The efficacy and safety of epidural infusions of levobupivacaine with and without clonidine for postoperative pain relief in patients undergoing total hip replacement. Anesth Analg 2000;91:393-7.
223. Singelyn FJ, Gouverneur JM, Robert A. A minimum dose of clonidine added to mepivacaine prolongs the duration of anesthesia and analgesia after axillary brachial plexus block. Anesth Analg 1996;83:1046-50.
224. Klamt JG, Garcia LV, Stocche RM, Meinberg AC. Epidural infusion of clonidine or clonidine plus ropivacaine for postoperative analgesia in children undergoing major abdominal surgery. J Clin Anesth 2003;15:510-14.
225. Santiveri X, Arxer A, Plaja I, et al. Anaesthetic and postoperative analgesic effects of spinal clonidine as an additive to prilocaine in the transurethral resection of urinary bladder tumours. Eur J Anaesthesiol 2002;19:589-93.
226. Jeffs SA, Hall JE, Morris S. Comparison of morphine alone with morphine plus clonidine for postoperative patient-controlled analgesia. Br J Anaesth 2002;89:424-7.
227. Striebel WH, Koenigs DI, Kramer JA. Intravenous clonidine fails to reduce postoperative meperidine requirements. J Clin Anesth 1993;5:221-5.
228. Aho MS, Erkola OA, Scheinin H, et al. Effect of intravenously administered dexmedetomidine on pain after laparoscopic tubal ligation. Anesth Analg 1991;73:112-8.
229. Jaakola ML. Dexmedetomidine premedication before intravenous regional anesthesia in minor outpatient hand surgery. J Clin Anesth 1994;6:204-11.
230. Arain SR, Ebert TJ. The efficacy, side effects, and recovery characteristics of dexmedetomidine versus propofol when used for intraoperative sedation. Anesth Analg 2002;95:461-6.
231. Arain SR, Ruehlow RM, Uhrich TD, Ebert TJ. The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery. Anesth Analg 2004;98:153-8.
232. Zárate E, Sá Rêgo MM, White PF, et al. Comparison of adenosine and remifentanil infusions as adjuvants to desflurane anesthesia. Anesthesiology 1999;90:956-63.
233. Fukunaga AF, Alexander GE, Stark CW. Characterization of the analgesic actions of adenosine: comparison of adenosine and remifentanil infusions in patients undergoing major surgical procedures. Pain 2003;101:129-38.
234. Yamamoto S, Yamaguchi H, Sakaguchi M, et al. Preoperative droperidol improved postoperative pain relief in patients undergoing rotator-cuff repair during general anesthesia using intravenous morphine. J Clin Anesth 2003;15:525-9.
235. Kara H, Sahin N, Ulusan V, Aydogdu T. Magnesium infusion reduces perioperative pain. Eur J Anaesthesiol 2002;19:52-6.
236. Lauretti GR, de Olivera R, Reis MP, et al. Study of three different doses of epidural neostigmine co-administered with lidocaine for postoperative analgesia. Anesthesiology 1999;90:1534-6.
237. Dirks J, Fredensborg BB, Christensen D, et al. A randomized study of the effects of single-dose gabapentin versus placebo on postoperative pain and morphine consumption after mastectomy. Anesthesiology 2002;97:560-4.
238. Fassoulaki A, Patris K, Sarantopoulos C, Hogan Q. The analgesic effect of gabapentin and mexiletine after breast surgery for cancer. Anesth Analg 2002;95:985-91.
239. Dierking G, Duedahl TH, Rasmussen ML, et al. Effects of gabapentin on postoperative morphine consumption and pain after abdominal hysterectomy: a randomized, double-blind trial. Acta Anaesthesiol Scand 2004;48:322-6.
240. Turan A, Karamanlioglu B, Memis D, et al. Analgesic effects of gabapentin after spinal surgery. Anesthesiology 2004;100:935-8.
241. Rorarius MG, Mennander S, Suominen P, et al. Gabapentin for the prevention of postoperative pain after vaginal hysterectomy. Pain 2004;110:175-81.
242. Dahl JB, Mathiesen O, Moiniche S. "Protective premedication": an option with gabapentin and related drugs? A review of gabapentin and pregabalin in the treatment of post-operative pain. Acta Anaesthesiol Scand 2004;48:1130-6.
243. Levaux C, Bonhomme V, Dewandre PY, et al. Effect of intraoperative magnesium sulphate on pain relief and patient comfort after major lumbar orthopaedic surgery. Anaesthesia 2003;58:131-5.
244. Bhatia A, Kashyap L, Pawar DK, Trikha A. Effect of intraoperative magnesium infusion on perioperative analgesia in open cholecystectomy. J Clin Anesth 2004;16:262-5.
245. Feld JM, Laurito CE, Beckerman M, et al. Non-opioid analgesia improves pain relief and decreases sedation after gastric bypass surgery. Can J Anaesth 2003;50:336-41.
246. Ko S-H, Lim H-R, Kim D-C, et al. Magnesium sulfate does not reduce postoperative analgesic requirements. Anesthesiology 2001;95:640-6.
247. Buvanendran A, McCarthy RJ, Kroin JS, et al. Intrathecal magnesium prolongs fentanyl analgesia: a prospective, randomized, controlled trial. Anesth Analg 2002;95:661-6.
248. Tan P-H, Kuo J-H, Liu K, et al. Efficacy of intrathecal neostigmine for the relief of postinguinal herniorrhaphy pain. Acta Anaesthesiol Scand 2000;44:1056-60.
249. Lauretti GR, de Loivera R, Perez MV, Paccola CA. Postoperative analgesia by intraarticular and epidural neostigmine following knee surgery. J Clin Anesth 2000;12:444-8.
250. Nakayama M, Ichinose H, Nakabayashi K, et al. Analgesic effect of epidural neostigmine after abdominal hysterectomy. J Clin Anesth 2001;13:86-9.
251. Turan A, Memis D, Basaran UN, et al. Caudal ropivacaine and neostigmine in pediatric surgery. Anesthesiology 2003;98:719-22.
252. Abdulatif M, El-Sanabary M. Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. Anesth Analg 2002;95:1215-8.
253. Almeida RA, Lauretti GR, Mattos AL. Antinociceptive effect of low-dose intrathecal neostigmine combined with intrathecal morphine following gynecologic surgery. Anesthesiology 2003;98:495-8.
254. Omais M, Lauretti GR, Paccola CA. Epidural morphine and neostigmine for postoperative analgesia after orthopedic surgery. Anesth Analg 2002;95:1698-701.
255. Tan PH, Chia YY, Lo Y, et al. Intrathecal bupivacaine with morphine or neostigmine for postoperative analgesia alter total knee replacement surgery. Can J Anaesth 2001;48:551-6.
256. Lauretti GR, Oliveira AP, Juliano MC, et al. Transdermal nitroglycerine enhances spinal neostigmine postoperative analgesia following gynecological surgery. Anesthesiology 2000;93:943-6.
257. Kaya FN, Sahin S, Owen MD, Eisenach JC. Epidural neostigmine produces analgesia but also sedation in women after cesarean delivery. Anesthesiology 2004;100:381-5.
258. Campbell FA, Tramer MR, Carroll D, et al. Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review. BJM 2001;323:13-6.
259. Buggy DJ, Toogood L, Marie S, et al. Lack of analgesic efficacy of oral delta-9-tetrahydrocannabinol in postoperative pain. Pain 2003;106:169-72.
260. Tarnow P, Cassuto J, Jonsson A, et al. Postoperative analgesia by D-myo-inositol-1,2,6-trisphosphate in patients undergoing cholecystectomy. Anesth Analg 1998;86:107-10.
261. White PF, Li S, Chiu JW. Electroanalgesia: its role in acute and chronic-pain management. Anesth Analg 2001;92:505-13.
262. White PF. Electroanalgesia: Does it have a place in the routine management of acute and chronic pain? Anesth Analg 2004;98:1197-8.
263. Wang B, Tang J, White PF, Naruse R, et al. Effect of the intensity of transcutaneous acupoint electrical stimulation on the postoperative analgesic requirement. Anesth Analg 1997;85:406-13.
264. Hamza MA, White PF, Ahmed HE, Ghoname EA. Effect of the frequency of transcutaneous electrical nerve stimulation on the postoperative opioid analgesic requirement and recovery profile. Anesthesiology 1999;91:1232-8.
265. Jensen JE, Conn RR, Hazelrigg G, Hewett JE. The use of transcutaneous neural stimulation and isokinetic testing in arthroscopic knee surgery. Am J Sports Med 1985;13:27-33.
266. Rakel B, Frantz R. Effectiveness of transcutaneous electrical nerve stimulation on postoperative pain with movement. J Pain 2003;4:455-64.
267. Carroll D, Tramer M, McQuay H, et al. Randomization is important in studies with pain outcomes: systematic review of transcutaneous electrical nerve stimulation in acute postoperative pain. Br J Anaesth 1996;77:798-803.
268. Chen L, Tang J, White PF, et al. The effect of the location of transcutaneous electrical nerve stimulation on postoperative opioid analgesic requirement: acupoint versus non-acupoint stimulation. Anesth Analg 1998;87:1129-34.
269. Lin JG, Lo MW, Wen YR, et al. The effect of high and low frequency electroacupuncture in pain after lower abdominal surgery. Pain 2002;99:509-14.
270. Kotani N, Hashimoto H, Sato Y, et al. Preoperative intradermal acupuncture reduces postoperative pain, nausea and vomiting, analgesic requirement, and sympathoadrenal responses. Anesthesiology 2001;95:359-56.
271. Sakurai M, Suleman MI, Morioka N, et al. Minute sphere acupressure does not reduce postoperative pain with morphine consumption. Anesth Analg 2003;96:493-7.
272. Tovar EA, Roethe RA, Weissig MD, et al. One-day admission for lung lobectomy: an incidental result of a clinical pathway. Ann Thorac Surg 1998;65:803-6.
273. Hashish I, Hai HK, Harvey W, et al. Reduction of postoperative pain and swelling by ultrasound treatment: a placebo effect. Pain 1988;33:303-11.
274. Gam AN, Thorsen H, Lonnberg F. The effect of low-level laser therapy on musculoskeletal pain: a meta-analysis. Pain 1993;52:63-6.
275. Pavlin DJ, Chen C, Penaloza DA, et al. Pain as a factor complicating recovery and discharge after ambulatory surgery. Anesth Analg 2003;97:1627-32.
276. Macario A, Weinger M, Carney S, Kim A. Which clinical anesthesia outcomes are important to avoid? The perspective of patients. Anesth Analg 1999;89:652-8.
277. Coloma M, Duffy LL, White PF, et al. Dexamethasone facilitates discharge after outpatient anorectal surgery. Anesth Analg 2001;92:85-8.
278. Aasboe V, Raeder JC, Groegaard B. Betamethasone reduces postoperative pain and nausea after ambulatory surgery. Anesth Analg 1998;87:319-23.
279. Kehlet H, Wilmore DW. Multimodal strategies to improve surgical outcome. Am J Surg 2002;183:630-41.
280. White PF. Changing role of COX-2 inhibitors in the perioperative period: is parecoxib really the answer? Anesth Analg 2005;100:1306-8.