Lack of analgesic efficacy of oral δ-9-tetrahydrocannabinol in postoperative pain

Pain

Volumn 106, Issue 1-2, 2003, Pages 169-172

  Buggy, Donal J ^b   Toogood, Lynn ^a   Maric, Shelagh ^a   Sharpe, Paul ^a   Lambert, David G ^a   Rowbotham, David J ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b MATER MISERICORDIAE UNIVERSITY HOSPITAL   (Ireland)

Author keywords

Cannabinoids; Pain; Postoperative; Randomized control trial; 9 Tetrahydrocannabinol

Indexed keywords

CANNABIS DERIVATIVE; DRONABINOL; PSYCHOTROPIC AGENT;

ABDOMINAL HYSTERECTOMY; ADULT; ANALGESIC ACTIVITY; ARTICLE; AWARENESS; BODY MOVEMENT; CLINICAL ARTICLE; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DROWSINESS; DRUG CAPSULE; DRUG EFFICACY; DRUG SCREENING; ELECTIVE SURGERY; FEMALE; HALLUCINATION; HEADACHE; HEART PALPITATION; HUMAN; MEMORY DISORDER; MOOD DISORDER; MUSCLE TWITCH; OUTCOMES RESEARCH; PAIN ASSESSMENT; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REST; SIDE EFFECT; SLURRED SPEECH; SURGICAL PATIENT; TIME; TREMOR; VERTIGO; VISUAL ANALOG SCALE; VISUAL IMPAIRMENT; XEROSTOMIA;

EID: 0142227167     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(03)00331-2     Document Type: Article

References (15)

1. Adams I.B., Martin B.R. Cannabis: pharmacology and toxicology in animals and humans. Addiction. 91:1996;1585-1614.
2. Ali P.B., Cotton B.R., Williamson K.M., Smith G. Intraperitoneal bupivacaine or lidocaine does not provide analgesia after total abdominal hysterectomy. Br J Anaesth. 80:1998;245-247.
3. Ashton C.H. Adverse effects of cannabis and cannabinoids. Br J Anaesth. 83:1999;637-649.
4. Beal J.E., Olson R., Laubenstein L., Morales J.O., Bellman P., Yangco B., Lefkowitz L., Plasse T.F., Shepard K.V. Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS. J Pain Symptom Manage. 10:1995;89-97.
5. Campbell F.A., Tramer M.R., Carroll D., Reynolds D.J., Moore R.A., McQuay H.J. Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative, systematic review. Br Med J. 323:2001;13-16.
6. Curtis G.B., Johnson G.H., Clark P., Taylor R., Brown J., O'Callaghan R., Shi M., Lacouture P.G. Relative potency of controlled-release oxycodone and controlled-release morphine in a postoperative pain model. Eur J Clin Pharmacol. 55:1999;425-429.
7. Hirst R.A., Lambert D.G., Notcutt W.G. Pharmacology and potential therapeutic uses of cannabis. Br J Anaesth. 81:1998;77-84.
8. Holdcroft A., Smith M., Jacklin A., Hodgson H., Smith B., Newton M., Evans F. Pain relief with oral cannabinoids in familial Mediterranean fever. Anaesthesia. 52:1997;483-486.
9. Kirk J.M., De Wit H. Responses to oral delta-9-tetrahydrocannabinol in frequent and infrequent marijuana users. Pharmacol Biochem Behav. 63:1999;137-142.
10. Martin B.R., Lichtman A.H. Cannabinoid transmission and pain perception. Neurobiol Dis. 5:1998;447-461.
11. Meng I.D., Manning B.H., Martin W.J., Fields H.L. An analgesia circuit activated by cannabinoids. Nature. 395:1998;381-383.
12. Noyes R., Brunk S.F., Avery D.H., Canter A. The analgesic properties of delta-9-tetrahydrocannabinol and codeine. Clin Pharmacol Ther. 18:1975;84-89.
13. Ravenscroft A., Ahmed Y.S., Burnside I.G. Chronic pain after SCI. A patient survey. Spinal Cord. 38:2000;611-614.
14. Voth E.A., Schwartz R.H. Medicinal applications of delta-9- tetrahydrocannabinol and marijuana. Ann Intern Med. 126:1997;791-798.
15. Ware M.A., Doyle C.R., Woods R., Lynch M.E., Clark A.J. Cannabis use for chronic non-cancer pain: results of a prospective survey. Pain. 102:2003;211-216.