Combination analgesic efficacy: Individual patient data meta-analysis of single-dose oral tramadol plus acetaminophen in acute postoperative pain

Journal of Pain and Symptom Management

Volumn 23, Issue 2, 2002, Pages 121-130

  Edwards, Jayne E ^a   McQuay, Henry J ^a   Moore, R Andrew ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Acetaminophen; Combination analgesic; Meta analysis; Randomized trial; Systematic review; Tramadol

Indexed keywords

IBUPROFEN; PARACETAMOL; TRAMADOL;

ADOLESCENT; ADULT; AGED; ANALGESIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DOUBLE BLIND PROCEDURE; DROWSINESS; DRUG EFFICACY; DRUG INDUCED DISEASE; HEADACHE; HUMAN; META ANALYSIS; NAUSEA; PAIN ASSESSMENT; POSTOPERATIVE PAIN; RANDOMIZED CONTROLLED TRIAL; TOOTH PAIN; TREATMENT OUTCOME; VERTIGO; VOMITING;

ACETAMINOPHEN; ACUTE DISEASE; ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MALE; MIDDLE AGED; PAIN, POSTOPERATIVE; RANDOMIZED CONTROLLED TRIALS; TRAMADOL;

EID: 0036177617     PISSN: 08853924     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0885-3924(01)00404-3     Document Type: Article

References (19)

1. Oral ibuprofen and diclofenac in postoperative pain: A quantitative systematic review
2. Single-patient data meta-analysis of 3453 postoperative patients: Oral tramadol versus placebo, codeine and combination analgesics
3. Single dose dextropropoxyphene in postoperative pain: A quantitative systematic review
4. Injected morphine in postoperative pain: A quantitative systematic review
5. Paracetamol with and without codeine in acute pain: A quantitative systematic review
6. Size is everything - Large amounts of information are needed to overcome random effects in estimating direction and magnitude of treatment effects
7. Seeking a simple measure of analgesia for mega-trials: Is a single global assessment good enough?
8. Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
9. Single-dose analgesic studies: The upside and downside of assay sensitivity
10. Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics
11. Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics: Verification from independent data
12. Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics: Use of pain intensity and visual analogue scales
13. Calculating confidence intervals for relative risk, odds ratios and standardised ratios and rates
14. The number needed to treat: A clinically useful measure of treatment effect
15. Single dose paracetamol (acetaminophen), with and without codeine, for postoperative pain
16. Using evidence from different sources: An example using paracetamol 1000 mg plus codeine 60 mg
17. Oral aspirin in postoperative pain: A quantitative systematic review
18. Practical methodology of meta-analyses (overviews) using updated individual patient data
19. Quantitative estimation of rare adverse events which follow a biological progression - A new model applied to chronic NSAID use