Perioperative small-dose S(+)-ketamine has no incremental beneficial effects on postoperative pain when standard-practice opioid infusions are used

Anesthesia and Analgesia

Volumn 94, Issue 4, 2002, Pages 981-986

  Jaksch, Wolfgang ^a   Lang, Stefan ^a   Reichhalter, Robert ^a   Raab, Gerald ^a   Dann, Klaus ^a   Fitzal, Sylvia ^a  

^a WILHELMINEN HOSPITAL   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

KETAMINE; KETANEST S; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROPOFOL; REMIFENTANIL; SODIUM CHLORIDE;

ADULT; ANTERIOR CRUCIATE LIGAMENT RUPTURE; ARTHROSCOPY; ARTICLE; BINDING AFFINITY; BODY MOVEMENT; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BINDING; DRUG INDUCED DISEASE; FEMALE; HUMAN; LIGAMENT SURGERY; MALE; PAIN RECEPTOR; PATIENT CONTROLLED ANALGESIA; PERIOPERATIVE PERIOD; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECEPTOR BINDING;

EID: 0036206848     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200204000-00038     Document Type: Article

References (25)

1. Preemptive analgesia: Treating postoperative pain by preventing the establishment of central sensitization
2. Wind-up and the NMDA receptor complex from a clinical perspective
3. Recent advances in the physiology and pharmacology of pain: Plasticity and its implication for clinical analgesia
4. Remembrance of times past: The significance of c-fos in pain
5. The benefits of intraoperative small-dose ketamine on postoperative pain after anterior cruciate ligament repair
6. Postoperative pain: The effect of low-dose ketamine in addition to general anesthesia
7. Preemptive ketamine decreases postoperative narcotic requirements in patients undergoing abdominal surgery
8. Ketamine reduces postoperative hyperalgesia
9. Efficacy of the NMDA antagonist ketamine in preemptive analgesia
10. Use and efficacy of low-dose ketamine in the management of acute postoperative pain: A review of current techniques and outcomes
11. Brain kinetics of (R)- and (S)-[N-methyl-11C] ketamine in the rhesus monkey studied by positron emission tomography (PET)
12. Effect of racemic mixture and the (S+)-isomer of ketamine on temporal and spatial summation of pain
13. Ketamine
14. Pre-emptive analgesia: Evidence, current status and future directions
15. The status of pre-emptive analgesia
16. Spinal cord pharmacology of pain
17. Evaluation of pain after arthroscopically assisted anterior cruciate ligament reconstruction
18. Pre-emptive analgesia
19. Postoperative pain management after intraoperative remifentanil
20. A review of the pharmacokinetics and pharmacodynamics of remifentanil
21. Rapid development of tolerance to analgesia during remifentanil infusion in humans
22. Acute opioid tolerance: Intraoperative remifentanil increases postoperative pain and morphine requirement
23. Lack of rapid development of opioid tolerance during alfentanil and remifentanil infusions for postoperative pain
24. The effect of ketamine on opioid-induced acute tolerance: Can it explain reduction of opioid consumption with ketamine-opioid analgesia combinations?
25. Mechanisms of hyperalgesia and morphine tolerance: A current view of their possible interactions