The injectable cyclooxygenase-2-specific inhibitor parecoxib sodium has analgesic efficacy when administered preoperatively

Anesthesia and Analgesia

Volumn 93, Issue 3, 2001, Pages 721-727

  Desjardins, Paul J ^a   Grossman, Evie H ^b   Kuss, Michael E ^b   Talwalker, Sheela ^b   Dhadda, Shobha ^b   Baum, Douglas ^a   Hubbard, Richard C ^b  

^a Premier Research   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; PARECOXIB; PLACEBO; UNCLASSIFIED DRUG; VALDECOXIB;

ANALGESIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE CALCULATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; PAIN; PAIN ASSESSMENT; PREOPERATIVE CARE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STOMACH ULCER;

EID: 0034858635     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200109000-00036     Document Type: Article

References (26)

1. Analgesic regimens for third molar surgery: Pharmacologic and behavioral considerations
2. Recent concepts in the neurophysiology of pain
3. The efficacy of nonopioid analgesics for postoperative dental pain: A meta-analysis
4. Postoperative analgesia and vomiting, with special reference to day-case surgery: A systematic review
5. Pharmacological and biochemical demonstration of the role of cyclooxygenase-2 in inflammation and pain
6. Efficacy of nonsteroidal anti-inflammatory drugs in the management of postoperative pain
7. Haemostatic effects of ketorolac with and without concomitant heparin in normal volunteers
8. Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis
9. NSAID induced gastrointestinal complications: The ARAMIS perspective-1997. Arthritis, Rheumatism, and Aging Medical Information System
10. Ketorolac in Europe
11. Ketorolac doses reduced
12. Parenteral ketorolac and risk of gastrointestinal and operative site bleeding: A postmarketing surveillance study
13. Metamizole: Reassessment of its therapeutic role
14. Pyrazolone derivatives
15. 4-[5-Methyl-3-phenylisoxasol4-yl]benzenesulfonamide, valdecoxib: A potent and selective inhibitor of COX-2
16. Single dose tolerability and pharmacokinetics of parecoxib sodium, a COX-2 specific inhibitor following intramuscular administration
17. Nonparametric confidence limits for survival probabilities and median survival time
18. Analgesic activity of single IV doses of parecoxib, a COX-2 specific inhibitor, and Toradol® in postoperative dental pain
19. Parecoxib, a new parental COX-2 specific inhibitor with an enhanced analgesic profile
20. Inhibition of tissue prostaglandin synthesis during third molar surgery: Use of preoperative fenbufen
21. Preoperative flurbiprofen in oral surgery: A method of choice in controlling postoperative pain
22. Comparison of preoperative postoperative diflunisal for suppression of postoperative pain
23. Pre-emptive analgesia: A systematic review of clinical studies
24. Pre-emptive analgesia: Why its effect is not always obvious
25. The COX-2 specific inhibitor, parecoxib sodium, does not impair platelet function in healthy elderly and nonelderly subjects: Two randomized, controlled trials