-
1
-
-
0035965343
-
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
-
Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA, Klein PS. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem. 2001;276:36734-36741.
-
(2001)
J Biol Chem
, vol.276
, pp. 36734-36741
-
-
Phiel, C.J.1
Zhang, F.2
Huang, E.Y.3
Guenther, M.G.4
Lazar, M.A.5
Klein, P.S.6
-
2
-
-
18244383806
-
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
-
Göttlicher M, Minucci S, Zhu P, et al. Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J. 2001;20:6969-6978.
-
(2001)
EMBO J
, vol.20
, pp. 6969-6978
-
-
Göttlicher, M.1
Minucci, S.2
Zhu, P.3
-
3
-
-
0036401554
-
Pharmacological and therapeutic properties of valproate: A summary after 35 years of clinical experience
-
Perucca E. Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience. CNS Drugs. 2002;16:695-714.
-
(2002)
CNS Drugs
, vol.16
, pp. 695-714
-
-
Perucca, E.1
-
4
-
-
0141834950
-
Suicide risk in bipolar disorder during treatment with lithium and divalproex
-
Goodwin FK, Fireman B, Simon GE, Hunkeler EM, Lee J, Revicki D. Suicide risk in bipolar disorder during treatment with lithium and divalproex. JAMA. 2003;290:1467-1473.
-
(2003)
JAMA
, vol.290
, pp. 1467-1473
-
-
Goodwin, F.K.1
Fireman, B.2
Simon, G.E.3
Hunkeler, E.M.4
Lee, J.5
Revicki, D.6
-
5
-
-
1542264835
-
Schizophrenia and valproate
-
Citrome L. Schizophrenia and valproate. Psychopharmacol Bull. 2003;37:74-88.
-
(2003)
Psychopharmacol Bull
, vol.37
, pp. 74-88
-
-
Citrome, L.1
-
6
-
-
3342900250
-
Bipolar disorder
-
Belmaker RH. Bipolar disorder. N Engl J Med. 2004;351:476-486.
-
(2004)
N Engl J Med
, vol.351
, pp. 476-486
-
-
Belmaker, R.H.1
-
7
-
-
16544383774
-
Anticonvulsant drugs in primary headaches prophylaxis
-
Frediani F. Anticonvulsant drugs in primary headaches prophylaxis. Neurol Sci. 2004;25:S161-S166.
-
(2004)
Neurol Sci
, vol.25
-
-
Frediani, F.1
-
8
-
-
21744444434
-
The evolving anticancer drug valproic acid: Insights into the mechanism and clinical studies
-
January 6, (Epub ahead of print)
-
Blaheta RA, Michaelis M, Hernáiz Driever P, Cinatl J Jr. The evolving anticancer drug valproic acid: insights into the mechanism and clinical studies. Med Res Rev January 6, 2005 (Epub ahead of print).
-
(2005)
Med Res Rev
-
-
Blaheta, R.A.1
Michaelis, M.2
Hernáiz Driever, P.3
Cinatl Jr., J.4
-
9
-
-
3042821974
-
Increased human cytomegalovirus replication in fibroblasts after treatment with therapeutical plasma concentrations of valproic acid
-
Michaelis M, Köhler N, Reinisch A, et al. Increased human cytomegalovirus replication in fibroblasts after treatment with therapeutical plasma concentrations of valproic acid. Biochem Pharmacol. 2004;68:531-538.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 531-538
-
-
Michaelis, M.1
Köhler, N.2
Reinisch, A.3
-
10
-
-
0036642408
-
Dynamics of CD4 and CD8 T cell responses to cytomegalovirus in healthy human donors
-
Dunn HS, Haney DJ, Ghanekar SA, Stepick-Biek P, Lewis DB, Maecker HT. Dynamics of CD4 and CD8 T cell responses to cytomegalovirus in healthy human donors. J Infect Dis. 2002;186:15-22.
-
(2002)
J Infect Dis
, vol.186
, pp. 15-22
-
-
Dunn, H.S.1
Haney, D.J.2
Ghanekar, S.A.3
Stepick-Biek, P.4
Lewis, D.B.5
Maecker, H.T.6
-
11
-
-
0037386571
-
Human cytomegalovirus retinitis: Pathogenicity, immune evasion and persistence
-
Scholz M, Doerr HW. Cinatl J Jr. Human cytomegalovirus retinitis: pathogenicity, immune evasion and persistence. Trends Microbiol. 2003;11:171-178.
-
(2003)
Trends Microbiol
, vol.11
, pp. 171-178
-
-
Scholz, M.1
Doerr, H.W.2
Cinatl Jr., J.3
-
13
-
-
18344376713
-
Apoptosis of human retina and retinal pigment cells induced by human cytomegalovirus infection
-
Chiou SH, Liu JH, Chen SS, et al. Apoptosis of human retina and retinal pigment cells induced by human cytomegalovirus infection. Ophthalmic Res. 2002;34:77-82.
-
(2002)
Ophthalmic Res
, vol.34
, pp. 77-82
-
-
Chiou, S.H.1
Liu, J.H.2
Chen, S.S.3
-
14
-
-
0029876303
-
Cytomegalovirus replication in human retinal pigment epithelial cells: Altered expression of viral early proteins
-
Detrick B, Rhame J, Wang Y, Nagineni CN, Hooks JJ. Cytomegalovirus replication in human retinal pigment epithelial cells: altered expression of viral early proteins. Invest Ophthalmol Vis Sci. 1996;37:814-825.
-
(1996)
Invest Ophthalmol Vis Sci
, vol.37
, pp. 814-825
-
-
Detrick, B.1
Rhame, J.2
Wang, Y.3
Nagineni, C.N.4
Hooks, J.J.5
-
15
-
-
0034667990
-
Decreased neutrophil adhesion to human cytomegalovirus-infected retinal pigment epithelial cells is mediated by virus-induced up-regulation of Fas ligand independent of neutrophil apoptosis
-
Cinatl J Jr, Blaheta R, Bittoova M, et al. Decreased neutrophil adhesion to human cytomegalovirus-infected retinal pigment epithelial cells is mediated by virus-induced up-regulation of Fas ligand independent of neutrophil apoptosis. J Immunol. 2000;165:4405-4413.
-
(2000)
J Immunol
, vol.165
, pp. 4405-4413
-
-
Cinatl Jr., J.1
Blaheta, R.2
Bittoova, M.3
-
16
-
-
0035881590
-
Human cytomegalovirus circumvents NF-kappa B dependence in retinal pigment epithelial cells
-
Cinatl J Jr, Margraf S, Vogel JU, Scholz M, Cinatl J, Doerr HW. Human cytomegalovirus circumvents NF-kappa B dependence in retinal pigment epithelial cells. J Immunol. 2001;167:1900-1908.
-
(2001)
J Immunol
, vol.167
, pp. 1900-1908
-
-
Cinatl Jr., J.1
Margraf, S.2
Vogel, J.U.3
Scholz, M.4
Cinatl, J.5
Doerr, H.W.6
-
17
-
-
0035478299
-
Up-regulation of Fas ligand expression by human cytomegalovirus immediate-early gene product 2: A novel mechanism in cytomegalovirus-induced apoptosis in human retina
-
Chiou SH, Liu JH, Hsu WM, et al. Up-regulation of Fas ligand expression by human cytomegalovirus immediate-early gene product 2: a novel mechanism in cytomegalovirus-induced apoptosis in human retina. J Immunol. 2001;167:4098-4103.
-
(2001)
J Immunol
, vol.167
, pp. 4098-4103
-
-
Chiou, S.H.1
Liu, J.H.2
Hsu, W.M.3
-
18
-
-
0035173703
-
Inhibition of human cytomegalovirus replication in a human retinal epithelial cell model by antisense oligonucleotides
-
Detrick B, Nagineni CN, Grillone LR, Anderson KP, Henry SP, Hooks JJ. Inhibition of human cytomegalovirus replication in a human retinal epithelial cell model by antisense oligonucleotides. Invest Ophthalmol Vis Sci. 2001;42:163-169.
-
(2001)
Invest Ophthalmol Vis Sci
, vol.42
, pp. 163-169
-
-
Detrick, B.1
Nagineni, C.N.2
Grillone, L.R.3
Anderson, K.P.4
Henry, S.P.5
Hooks, J.J.6
-
19
-
-
18644374841
-
2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections
-
Snoeck R, Andrei G, Bodaghi B, et al. 2-Chloro-3-pyridin-3-yl-5,6,7,8- tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections. Antiviral Res. 2002;55:413-424.
-
(2002)
Antiviral Res
, vol.55
, pp. 413-424
-
-
Snoeck, R.1
Andrei, G.2
Bodaghi, B.3
-
20
-
-
0037311135
-
Impaired killing of HCMV-infected retinal pigment epithelial cells by anti-pp65 CD8(+) cytotoxic T cells
-
Allart S, Lule J, Serres B, et al. Impaired killing of HCMV-infected retinal pigment epithelial cells by anti-pp65 CD8(+) cytotoxic T cells. Invest Ophthalmol Vis Sci. 2003;44:665-671.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 665-671
-
-
Allart, S.1
Lule, J.2
Serres, B.3
-
21
-
-
0037406824
-
Differential expression of chemokines by human retinal pigment epithelial cells infected with cytomegalovirus
-
Momma Y, Nagineni CN, Chin MS, Srinivasan K, Detrick B, Hooks JJ. Differential expression of chemokines by human retinal pigment epithelial cells infected with cytomegalovirus. Invest Ophthalmol Vis Sci. 2003;44:2026-2033.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 2026-2033
-
-
Momma, Y.1
Nagineni, C.N.2
Chin, M.S.3
Srinivasan, K.4
Detrick, B.5
Hooks, J.J.6
-
22
-
-
1442309439
-
Thrombin stimulates IL-6 and IL-8 expression in cytomegalovirus-infected human retinal pigment epithelial cells
-
Scholz M, Vogel JU, Höver G, et al. Thrombin stimulates IL-6 and IL-8 expression in cytomegalovirus-infected human retinal pigment epithelial cells. Int J Mol Med. 2004;13:327-331.
-
(2004)
Int J Mol Med
, vol.13
, pp. 327-331
-
-
Scholz, M.1
Vogel, J.U.2
Höver, G.3
-
23
-
-
0035992780
-
Valproate and valproate-analogues: Potent tools to fight against cancer
-
Blaheta RA, Nau H, Michaelis M, Cinatl J Jr. Valproate and valproate-analogues: potent tools to fight against cancer. Curr Med Chem. 2002;9:1417-1433.
-
(2002)
Curr Med Chem
, vol.9
, pp. 1417-1433
-
-
Blaheta, R.A.1
Nau, H.2
Michaelis, M.3
Cinatl Jr., J.4
-
25
-
-
6044256118
-
Histones and histone modifications
-
Peterson CL, Laniel MA. Histones and histone modifications. Curr Biol. 2004;14:R546-R551.
-
(2004)
Curr Biol
, vol.14
-
-
Peterson, C.L.1
Laniel, M.A.2
-
26
-
-
0036500165
-
Control of cytomegalovirus lytic gene expression by histone acetylation
-
Murphy JC, Fischle W, Verdin E, Sinclair JH. Control of cytomegalovirus lytic gene expression by histone acetylation. EMBO J. 2002;21:1112-1120.
-
(2002)
EMBO J
, vol.21
, pp. 1112-1120
-
-
Murphy, J.C.1
Fischle, W.2
Verdin, E.3
Sinclair, J.H.4
-
27
-
-
10344222687
-
Human cytomegalovirus immediate-early 1 protein facilitates viral replication by antagonizing histone deacetylation
-
Nevels M, Paulus C, Shenk T. Human cytomegalovirus immediate-early 1 protein facilitates viral replication by antagonizing histone deacetylation. Proc Natl Acad Sci USA. 2004;101:17234-17239.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17234-17239
-
-
Nevels, M.1
Paulus, C.2
Shenk, T.3
-
28
-
-
0035943699
-
The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth
-
Yuan PX, Huang LD, Jiang YM, Gutkind JS, Manji HK, Chen G. The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. J Biol Chem. 2001;276:31674-31683.
-
(2001)
J Biol Chem
, vol.276
, pp. 31674-31683
-
-
Yuan, P.X.1
Huang, L.D.2
Jiang, Y.M.3
Gutkind, J.S.4
Manji, H.K.5
Chen, G.6
-
29
-
-
0842325787
-
Histone deacetylase is a target of valproic acid-mediated cellular differentiation
-
Gurvich N, Tsygankova OM, Meinkoth JL, Klein PS. Histone deacetylase is a target of valproic acid-mediated cellular differentiation. Cancer Res. 2004;64:1079-1086.
-
(2004)
Cancer Res
, vol.64
, pp. 1079-1086
-
-
Gurvich, N.1
Tsygankova, O.M.2
Meinkoth, J.L.3
Klein, P.S.4
-
30
-
-
3242788185
-
Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis
-
Hao Y, Creson T, Zhang L, et al. Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis. J Neurosci. 2004;24:6590-6599.
-
(2004)
J Neurosci
, vol.24
, pp. 6590-6599
-
-
Hao, Y.1
Creson, T.2
Zhang, L.3
-
31
-
-
0026001902
-
Valproic acid-induced neural tube defects in the mouse and human: Aspects of chirality, alternative drug development, pharmacokinetics and possible mechanisms
-
Nau H, Hauck RS, Ehlers K. Valproic acid-induced neural tube defects in the mouse and human: aspects of chirality, alternative drug development, pharmacokinetics and possible mechanisms. Pharmacol Toxicol. 1991;69:310-321.
-
(1991)
Pharmacol Toxicol
, vol.69
, pp. 310-321
-
-
Nau, H.1
Hauck, R.S.2
Ehlers, K.3
-
32
-
-
0031694133
-
Studies on the teratogen pharmacophore of valproic acid analogues: Evidence of interactions at a hydrophobic centre
-
Bojic U, Ehlers K, Ellerbeck U, et al. Studies on the teratogen pharmacophore of valproic acid analogues: evidence of interactions at a hydrophobic centre. Eur J Pharmacol. 1998;354:289-299.
-
(1998)
Eur J Pharmacol
, vol.354
, pp. 289-299
-
-
Bojic, U.1
Ehlers, K.2
Ellerbeck, U.3
-
34
-
-
0033060174
-
Human cytomegalovirus infection decreases expression of thrombospondin-1 independent of the tumor suppressor protein p53
-
Cinatl J Jr, Kotchetkov R, Scholz M, et al. Human cytomegalovirus infection decreases expression of thrombospondin-1 independent of the tumor suppressor protein p53. Am J Pathol. 1999;155:285-292.
-
(1999)
Am J Pathol
, vol.155
, pp. 285-292
-
-
Cinatl Jr., J.1
Kotchetkov, R.2
Scholz, M.3
-
35
-
-
0029142502
-
In vitro inhibition of human cytomegalovirus replication in human foreskin fibroblasts and endothelial cells by ascorbic acid 2-phosphate
-
Cinatl J Jr, Cinatl J, Weber B, et al. In vitro inhibition of human cytomegalovirus replication in human foreskin fibroblasts and endothelial cells by ascorbic acid 2-phosphate. Antiviral Res. 1995;27:405-418.
-
(1995)
Antiviral Res
, vol.27
, pp. 405-418
-
-
Cinatl Jr., J.1
Cinatl, J.2
Weber, B.3
-
36
-
-
0029949334
-
In vitro inhibition of human cytomegalovirus replication by calcium triatrium diethylenetriaminepentaacetic acid
-
Cinatl J Jr, Hoffmann F, Cinatl J, et al. In vitro inhibition of human cytomegalovirus replication by calcium triatrium diethylenetriaminepentaacetic acid. Antiviral Res. 1996;31:23-34.
-
(1996)
Antiviral Res
, vol.31
, pp. 23-34
-
-
Cinatl Jr., J.1
Hoffmann, F.2
Cinatl, J.3
-
37
-
-
0027427808
-
Malformations, withdrawal manifestations, and hypoglycaemia after exposure to valproate in utero
-
Thisted E, Ebbesen F. Malformations, withdrawal manifestations, and hypoglycaemia after exposure to valproate in utero. Arch Dis Child. 1993;69:288-291.
-
(1993)
Arch Dis Child
, vol.69
, pp. 288-291
-
-
Thisted, E.1
Ebbesen, F.2
-
39
-
-
0037806885
-
Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway
-
Chang F, Steelman LS, Shelton JG, et al. Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway. Int J Oncol. 2003;22:469-480.
-
(2003)
Int J Oncol
, vol.22
, pp. 469-480
-
-
Chang, F.1
Steelman, L.S.2
Shelton, J.G.3
-
40
-
-
0141757460
-
MAPK pathways in radiation responses
-
Dent P, Yacoub A, Fisher PB, Hagan MP, Grant S. MAPK pathways in radiation responses. Oncogene. 2003;22:5885-5896.
-
(2003)
Oncogene
, vol.22
, pp. 5885-5896
-
-
Dent, P.1
Yacoub, A.2
Fisher, P.B.3
Hagan, M.P.4
Grant, S.5
-
41
-
-
0029033035
-
Sodium valproate, an anticonvulsant drug, stimulates human cytomegalovirus replication
-
Kuntz-Simon G, Obert G. Sodium valproate, an anticonvulsant drug, stimulates human cytomegalovirus replication. J Gen Virol. 1995;76:1409-1415.
-
(1995)
J Gen Virol
, vol.76
, pp. 1409-1415
-
-
Kuntz-Simon, G.1
Obert, G.2
-
42
-
-
0345060878
-
Functional profiling of a human cytomegalovirus genome
-
Dunn W, Chou C, Li H, et al. Functional profiling of a human cytomegalovirus genome. Proc Natl Acad Sci USA. 2003;100:14223-14228.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 14223-14228
-
-
Dunn, W.1
Chou, C.2
Li, H.3
-
43
-
-
0043240266
-
The role of the extracellular signal-regulated kinase signaling pathway in mood modulation
-
Einat H, Yuan P, Gould TD, et al. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. J Neurosci. 2003;23:7311-7316.
-
(2003)
J Neurosci
, vol.23
, pp. 7311-7316
-
-
Einat, H.1
Yuan, P.2
Gould, T.D.3
-
44
-
-
13644254946
-
Comparative analysis of the effects of four mood stabilizers in SH-SY5Y cells and in primary neurons
-
Di Daniel E, Mudge AW, Maycox PR. Comparative analysis of the effects of four mood stabilizers in SH-SY5Y cells and in primary neurons. Bipolar Disord. 2005;7:33-41.
-
(2005)
Bipolar Disord
, vol.7
, pp. 33-41
-
-
Di Daniel, E.1
Mudge, A.W.2
Maycox, P.R.3
-
45
-
-
0032838076
-
Hypersensitivity syndrome due to 2 anticonvulsant drugs
-
Conilleau V, Dompmartin A, Verneuil L, Michel M, Leroy D. Hypersensitivity syndrome due to 2 anticonvulsant drugs. Contact Dermatitis. 1999;41:141-144.
-
(1999)
Contact Dermatitis
, vol.41
, pp. 141-144
-
-
Conilleau, V.1
Dompmartin, A.2
Verneuil, L.3
Michel, M.4
Leroy, D.5
-
46
-
-
0032832771
-
The use of valproic acid in HIV-positive patients
-
Jennings HR, Romanelli F. The use of valproic acid in HIV-positive patients. Ann Pharmacother. 1999;33:1113-1116.
-
(1999)
Ann Pharmacother
, vol.33
, pp. 1113-1116
-
-
Jennings, H.R.1
Romanelli, F.2
|