Differential expression of chemokines by human retinal pigment epithelial cells infected with cytomegalovirus

Investigative Ophthalmology and Visual Science

Volumn 44, Issue 5, 2003, Pages 2026-2033

  Momma, Yuko ^a,c   Nagineni, Chandrasekharam N ^a   Chin, Marian S ^a   Srinivasan, Kumar ^a   Detrick, Barbara ^b   Hooks, John J ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; INTERLEUKIN 8; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; RANTES;

ARTICLE; CYTOMEGALOVIRUS INFECTION; CYTOPATHOGENIC EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IMMUNOPATHOGENESIS; PIGMENT CELL; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; VIRUS CULTURE; VIRUS REPLICATION;

CELLS, CULTURED; CHEMOKINE CCL2; CHEMOKINES; CYTOMEGALOVIRUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMANS; INTERFERON TYPE II; PIGMENT EPITHELIUM OF EYE; PLAQUE ASSAY; RECEPTORS, CHEMOKINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VIRUS REPLICATION;

EID: 0037406824     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.02-0980     Document Type: Article

References (62)

1. Wakefield D, Lloyd A. The role of cytokines in the pathogenesis of inflammatory eye disease. Cytokine 1992;4:1-5.
2. Miller MD, Krangel MS. Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. Crit Rev Immunol. 1992;12:17-46.
3. Luster AD. Chemokines: chemotactic cytokines that mediate inflammation. N Engl J Med. 1998;338:436-445.
4. Murphy PM, Baggiolini M, Charo IF, et al. International union of Pharmacology. XXII. Nomenclature for chemokine receptors. Pharmcol Rev. 2000;52:145-176.
5. Baggiolini M. Chemokines and leukocyte traffic. Nature. 1998;392:565-568.
6. Premack BA, Schall TJ. Chemokine receptors: gateways to inflammation and infection. Nat Med. 1996;2:1174-1178.
7. Zlotnik A, Morales J, Hedrick JA. Recent advances in chemokines and chemokine receptors. Crit Rev Immunol. 1999;19:1-47.
8. Rossi D, Zlotnik A. The biology of chemokines and chemokine receptors. Annu Rev Immunol. 2000;18:217-242.
9. Hall LR, Pearlman E. Pathogenesis of onchocercal keratitis (river blindness). Clin Microbiol Rev. 1999;12:445-453.
10. Adamus G, Manczak M, Machinicki M. Expression of CC chemokines and their receptors in the eye in autoimmune anterior uveitis associated with EAE. Invest Ophthalmol Vis Sci. 2001;42:2894-2903.
11. Mahalingam S, Clark K, Matthaei KI, Foster PS. Antiviral potential of chemokines. Bioessays. 2001;23:428-435.
12. Mogensen TH, Paludan SR. Molecular pathways in virus-induced cytokine production. Microbiol Mol Biol Rev. 2001;65:131-150.
13. Salazar-Mather TP, Hamilton TA, Biron CA. A chemokine to cytokine to chemokine cascade critical in antiviral defence. J Clin Invest. 2000;105:985-993.
14. Hadida F, Vieillard V, Moleet L, et al. RANTES regulates Fas ligand expression and killing by HIV-specific CD8 cytotoxic T cells. J Immunol. 1999;163:1105-1109.
15. Chiou SH, Liu JH, Hsu WM, et al. Up-regulation of Fas ligand expression by human cytomegalovirus immediate-early gene product 2: a novel mechanism in cytomegalovirus-induced apoptosis in human retina. J Immunol. 2001;167:4098-4103.
16. Dragic T, Litwin V, Allaway GP, et al. HIV-1 entry into CD 4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature. 1996; 381:667-673.
17. Fortunato EA, McElroy AK, Sanchez V, Spector DH. Exploitation of cellular signaling and regulatory pathways by human cytomegalovirus. Trends Microbiol. 2000;8:111-119.
18. Ploegh HL. Viral strategies of immune evasion. Science. 1998;280:248-253.
19. Michelson S. Human cytomegalovirus escape from immune detection. Intervirology. 1999;42:301-307.
20. Chee MS, Satchwell SC, Preddie E, Weston KM, Barell BG. Human cytomegalovirus encodes three G protein-coupled receptor homologues. Nature. 1990;344:774-777.
21. Kuhn DE, Beall CJ, Kolattukudy PE. The cytomegalovirus US28 protein binds multiple CC chemokines with high affinity. Biochem Biophys Res Commun. 1995;211:325-330.
22. Smith GL. Virus proteins that bind cytokines, chemokines or interferons. Curr Opin Immunol. 1996;8:467-471.
23. Bodaghi B, Jones TR, Zipeto D, et al. Chemokine sequestration by viral chemoreceptors as a novel viral escape strategy: withdrawal of chemokines from the environment of cytomegalovirus-infected cens. J Exp Med. 1998;188:855-866.
24. Billstrom MA, Lehman LA, Worthen GS. Depletion of extracellular RANTES during human cytomegalovirus infection of endothelial cells. Am J Respir Cell Mol Biol. 1999;21:163-167.
25. Rubin RH, Tolkoff-Rubin NE, Oliver D, et al. Multicenter seroepideniologic study of the impact of cytomegalovirus infection on renal transplantation. Transplantation. 1985;40:243-249.
26. Willebrand EV, Petterson E, Ahonen J, Hayry P. CMV infection, class II antigen expression, and human kidney allograft rejection. Transplantation. 1986;42:364-367.
27. O'Grady JG, Sutherland S, Harvey F, et al. Cytomegalovirus infection and donor/recipient HLA antigens: interdependent co-factors in pathogenesis of vanishing bileduct syndrome after liver transplantation. Lancet. 1988;6:302-305.
28. Jabs DA. Ocular manifestation of HIV infection. Trans Am Ophthalmol Soc. 1995;93:623-683.
29. Guembel HOC, Ohrloff C. Opportunistic infections of the eye in immunocompromised patients. Ophthalmologica. 1997;211:53-61.
30. Holland GN, Gottlieb MS, Yee RD, Schanker HM, Pettit TH. Ocular disorders associated with a new severe acquired cellular immuno-deficiency syndrome. Am J Ophthalmol. 1982;93:393-402.
31. Holland GN, Pepose JS, Pettit TH, et al. Acquired immune deficiency syndrome: ocular manifestations. Ophthalmology. 1983;90:859-872.
32. Egbert PR, Pollard RB, Gallagher JG, Merigan TC. Cytomegalovirus retinitis in immunosuppressed hosts. II. Ocular manifestations. Ann Intern Med. 1980;93:664-670.
33. Pepose JS, Nestor MS, Holland GN, et al. An analysis of retinal cotton-wool spots and cytomegalovirus retinitis in the acquired immunodeficiency syndrome. Am J Ophthalmol. 1983;95:118-120.
34. Jabs DA, Enger C, Haller J, Bustros SD. Retinal detachments in patients with cytomegalovirus retinitis. Arch Ophthalmol. 1991; 109:794-799.
35. Gross JG, Bozzette S, Mathews WC, et al. Longitudinal study of cytomegalovirus retinitis in acquired immune deficiency syndrome. Ophthalmology. 1990;97:681-686.
36. Rao NA, Zhang J, Ishimoto S. Role of retinal vascular endothelial cells in development of CMV retinitis. Trans Am Ophthalmol Soc. 1998;96:111-123.
37. Pepose JS, Holland GN, Nestor MS, Cochran AJ, Foos RY. Acquired immune deficiency syndrome: pathogenic mechanisms of ocular disease. Ophthalmology. 1985;92:472-484.
38. Pepose JS, Newman C, Bach MC, et al. Pathologic features of cytomegalovirus retinopathy after treatment with the antiviral agent ganciclovir. Ophthalmology. 1987;94:414-424.
39. Magone MT, Nussenblatt RD, Whitcup SM. Evaluation of laser flare photometry in patients with cytomegalovirus retinitis and AIDS. Am J Ophthalmol. 1997;124:190-198.
40. Nussenblatt RB, Lane HC. Human immunodeficiency virus disease: changing patterns of intraocular inflammation. Am J Ophthalmol. 1998;125:374-382.
41. Kolb H. The neural organization of the human retina. In: Heckenlively JR, Arden GB, eds. Principles and Practices of Clinical Electrophysiology of Vision. St. Louis: Mosby Year Book, Inc.; 1991:25-52.
42. Bok D. The retinal pigment epithelium: a versatile partner in vision. J Cell Sci. 1993;17(suppl):189-195.
43. Liversidge J, Forrester JV. Regulation of immune responses by the retinal pigment epithelium. In: Marmor MF, Wolfensburger TJ, eds. The Retinal Pigment Epithelium: Function and Disease. New York: Oxford University Press; 1998:511-527.
44. Rao NA. Inflammations and infections of the retinal pigment epithelium. In: Marmor MF, Wolfensburger TJ, eds. The Retinal Pigment Epithelium: Function and Disease. New York: Oxford University Press; 1998:528-541.
45. Detrick B, Rhame J, Wang Y, Nagineni CN, Hooks JJ. Cytomegalovirus replication in human retinal pigment epithelial cells: altered expression of viral early proteins. Invest Ophthalmol Vis Sci. 1996;37:814-825.
46. Detrick B, Nagineni CN, Grillone LR, Anderson KP, Henry SP, Hooks JJ. Inhibition of human cytomegalovirus replication in a human retinal epithelial cell model by antisense oligonucleotides. Invest Ophthalmol Vis Sci. 2001;42:163-169.
47. Nagineni CN, Detrick B, Hooks JJ. Synergistic effects of gamma interferon on inflammatory mediators that induce interleukin-6 gene expression and secretion by human retinal pigment epithelial cells. Clin Diagn Lab Immunol. 1994;1:569-577.
48. Nagineni CN, Detrick B, Hooks JJ. Toxoplasma gondii infection induces gene expression and secretion of interleukin-1 (IL-1), IL-6, granulocyte-macrophage colony-stimulating factor, and intercellular adhesion molecule 1 by human retinal pigment epithelial cells. Infect Immun. 2000;68:407-410.
49. Murayama T, Ohara Y, Obuchi M, et al. Human cytomegalovirus induces interleukin-8 production by a human monocytic cell line, THP-1, through acting concurrently on AP-1 and NF-kB-binding sites of the interleukin gene. J Virol. 1997;71:5692-5695.
50. Murayama T, Mukaida N, Khaber KS, Matsushima K. Potential involvement of IL-8 in the pathogenesis of human cytomegalovirus infection. J Leukoc Biol. 1998;64:62-67.
51. Craigen JL, Yong KL, Jordan NJ, et al. Human cytomegalovirus infection up-regulates interleukin-8 gene expression and stimulates neutrophil transendothelial migration. Immunology. 1997; 92:138-145.
52. Cinatl J Jr, Blaheta R, Bittoova M, et al. Decreased neutrophil adhesion to human cytomegalovirus-infected retinal pigment epithelial cells is mediated by virus-induced up-regulation of Fas ligand independent of neutrophil apoptosis. J Immunol. 2000; 165:4405-4413.
53. Schroeder MB, Worthen GS. Viral regulation of RANTES expression during human cytomegalovirus infection of endothelial cells. J Virol. 2001;75:3383-3390.
54. Penfold MET, Dairaghi D, Duke GM, et al. Cytomegalovirus encodes a potent α chemokine. Proc Natl Acad Sci USA. 1999;96:9839-9844.
55. Michelson S, Monte PD, Zipeto D, et al. Modulation of RANTES production by human cytomegalovirus infection of fibroblasts. J Virol. 1997;71:6495-6500.
56. Hirsch AJ, Shenk T. Human cytomegalovirus inhibits transcription of the CC chemokine MCP-1 gene. J Virol. 1999;73:404-410.
57. Mitamura Y, Takeuchi S, Matsuda A, et al. Monocyte chemotactic protein-1 in the vitreous of patients with proliferative diabetic retinopathy. Ophthalmologica. 2001;215:415-418.
58. Elner SG, Elner VM, Jaffe GJ, et al. Cytokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy. Curr Eye Res. 1995;14:1045-1053.
59. Capeans C, De Rojas MV, Lojo S, Salorio MS. C-C chemokines in the vitreous of patients with proliferative vitreoretinopathy and proliferative diabetic retinopathy. Retina. 1998;18:546-550.
60. Britt WJ, Alford CA. Cytomegalovirus. In: Fields BN, Knipe DM, Howley PM, eds. Fields's Virology. Philadelphia: Lippincott-Raven; 1996:2493-2523.
61. Beisser PS, Goh CS, Cohen FE, Michelson S. Viral chemokine receptors and chemokines in human cytomegalovirus trafficking and interaction with the immune system: CMV chemokine receptors. Curr Top Microbiol Immunol. 2002;269:203-234.
62. Robinson MR, Reed G, Csaky KG, Polis MA, Whitcup SM. Immunerecovery uveitis in patients with cytomegalovirus retinitis taking highly active antiretroviral therapy. Am J Ophthalmol. 2000;130:49-56.