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Volumn 146, Issue 3, 2005, Pages 397-407

Ion transport regulated by protease-activated receptor 2 in human airway Calu-3 epithelia

Author keywords

Airway ion transport; Cl secretion; Desensitization; Phosphatidylcholine phospholipase C; Protease activated receptor 2; Protein kinase C; Purinoceptor

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 ETHYL 2 BENZIMIDAZOLINONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; ADENOSINE; CALCIUM ION; CHLORIDE ION; FORSKOLIN; INOSITOL 1,4,5 TRISPHOSPHATE; ISOPRENALINE; KETONE DERIVATIVE; NYSTATIN; PHORBOL 12 ACETATE 13 MYRISTATE; PHOSPHATIDYLINOSITOL DIACYLGLYCEROL LYASE; PROTEIN; PROTEIN KINASE C INHIBITOR; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 2 ACTIVATING PEPTIDE; PURINE RECEPTOR; THAPSIGARGIN; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE; TRYPSIN; UNCLASSIFIED DRUG; XESTOSPONGIN C;

EID: 27144480127     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706330     Document Type: Article
Times cited : (18)

References (54)
  • 1
    • 0026503978 scopus 로고
    • Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack
    • AIKAWA, T., SHIMURA, S., SASAKI, H., EBINA, M. & TAKISHIMA, T. (1992). Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack. Chest, 101, 916-921.
    • (1992) Chest , vol.101 , pp. 916-921
    • Aikawa, T.1    Shimura, S.2    Sasaki, H.3    Ebina, M.4    Takishima, T.5
  • 2
    • 0030480576 scopus 로고    scopus 로고
    • The antiviral, antitumoural xanthate D609 is a competitive inhibitor of phosphatidylcholine-specific phospholipase C
    • AMTMANN, E. (1996). The antiviral, antitumoural xanthate D609 is a competitive inhibitor of phosphatidylcholine-specific phospholipase C. Drugs. Exp. Clin. Res., 22, 287-294.
    • (1996) Drugs. Exp. Clin. Res. , vol.22 , pp. 287-294
    • Amtmann, E.1
  • 3
    • 0029786481 scopus 로고    scopus 로고
    • Mechanisms of desensitization and resensitization of proteinase-activated receptor-2
    • BOHM, S.K., KHITIN, L.M., GRADY, E.F., APONTE, G., PAYAN, D.G. & BUNNETT, N.W. (1996). Mechanisms of desensitization and resensitization of proteinase-activated receptor-2. J. Biol. Chem., 271, 22003-22016.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22003-22016
    • Bohm, S.K.1    Khitin, L.M.2    Grady, E.F.3    Aponte, G.4    Payan, D.G.5    Bunnett, N.W.6
  • 4
    • 0033214598 scopus 로고    scopus 로고
    • 2+ mobilization triggered by a lipid factor isolated from vitreous body
    • 2+ mobilization triggered by a lipid factor isolated from vitreous body. J. Biol. Chem., 274, 28134-28141.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28134-28141
    • Camina, J.P.1    Casabiell, X.2    Casanueva, F.F.3
  • 6
    • 0034161592 scopus 로고    scopus 로고
    • Protease-activated receptors: Sentries for inflammation?
    • COCKS, T.M. & MOFFATT, J.D. (2000). Protease-activated receptors: sentries for inflammation? Trends Pharmacol. Sci., 21, 103-108.
    • (2000) Trends Pharmacol. Sci. , vol.21 , pp. 103-108
    • Cocks, T.M.1    Moffatt, J.D.2
  • 7
    • 0034938379 scopus 로고    scopus 로고
    • Protease-activated receptor-2 (PAR2) in the airways
    • COCKS, T.M. & MOFFATT, J.D. (2001). Protease-activated receptor-2 (PAR2) in the airways. Pulm. Pharmacol. Ther., 14, 183-191.
    • (2001) Pulm. Pharmacol. Ther. , vol.14 , pp. 183-191
    • Cocks, T.M.1    Moffatt, J.D.2
  • 9
    • 0035955442 scopus 로고    scopus 로고
    • Second messengers in platelet aggregation evoked by serotonin and A23187, a calcium ionophore
    • CONNOR, J.D., RASHEED, H., GILANI, A.H., CHEEMA, M., RIZVI, Z. & SAEED, S.A. (2001). Second messengers in platelet aggregation evoked by serotonin and A23187, a calcium ionophore. Life Sci., 69, 2759-2764.
    • (2001) Life Sci. , vol.69 , pp. 2759-2764
    • Connor, J.D.1    Rasheed, H.2    Gilani, A.H.3    Cheema, M.4    Rizvi, Z.5    Saeed, S.A.6
  • 10
    • 0036462593 scopus 로고    scopus 로고
    • + channels underlying anion secretion in the human airway cell line Calu-3
    • + channels underlying anion secretion in the human airway cell line Calu-3. J. Physiol., 538, 747-757.
    • (2002) J. Physiol. , vol.538 , pp. 747-757
    • Cowley, E.A.1    Linsdell, P.2
  • 11
    • 0034979246 scopus 로고    scopus 로고
    • Protease-activated receptor-2-mediated inhibition of ion transport in human bronchial epithelial cells
    • DANAHAY, H., WITHEY, L., POLL, C.T., VAN DE GRAAF, S.F. & BRIDGES, R.J. (2001). Protease-activated receptor-2-mediated inhibition of ion transport in human bronchial epithelial cells. Am. J. Physiol. Cell Physiol., 280, C1455-C1464.
    • (2001) Am. J. Physiol. Cell Physiol. , vol.280
    • Danahay, H.1    Withey, L.2    Poll, C.T.3    Van De Graaf, S.F.4    Bridges, R.J.5
  • 12
    • 0028970963 scopus 로고
    • ET-18-OCH3 inhibits nuclear factor-kappa B activation by 12-O-tetradecanoylphorbol-13-acetate but not by tumor necrosis factor-alpha or interleukin 1 alpha
    • DANIEL, L.W., CIVOLI, F., ROGERS, M.A., SMITHERMAN, P.K., RAJU, P.A. & ROEDERER, M. (1995). ET-18-OCH3 inhibits nuclear factor-kappa B activation by 12-O-tetradecanoylphorbol-13-acetate but not by tumor necrosis factor-alpha or interleukin 1 alpha. Cancer Res., 55, 4844-4849.
    • (1995) Cancer Res. , vol.55 , pp. 4844-4849
    • Daniel, L.W.1    Civoli, F.2    Rogers, M.A.3    Smitherman, P.K.4    Raju, P.A.5    Roederer, M.6
  • 13
    • 0031744875 scopus 로고    scopus 로고
    • Proteinase-activated receptors: Novel mechanisms of signaling by serine proteases
    • DERY, O., CORVERA, C.U., STEINHOFF, M. & BUNNETT, N.W. (1998). Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am. J. Physiol., 274, C1429-C1452.
    • (1998) Am. J. Physiol. , vol.274
    • Dery, O.1    Corvera, C.U.2    Steinhoff, M.3    Bunnett, N.W.4
  • 15
    • 0030964614 scopus 로고    scopus 로고
    • Xestospongins: Potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor
    • GAFNI, J., MUNSCH, J.A., LAM, T.H., CATLIN, M.C., COSTA, L.G., MOLINSKI, T.F. & PESSAH, I.N. (1997). Xestospongins: potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor. Neuron, 19, 723-733.
    • (1997) Neuron , vol.19 , pp. 723-733
    • Gafni, J.1    Munsch, J.A.2    Lam, T.H.3    Catlin, M.C.4    Costa, L.G.5    Molinski, T.F.6    Pessah, I.N.7
  • 16
    • 0028292615 scopus 로고
    • CFTR in Calu-3 human airway cells: Channel properties and role in cAMP-activated Cl- Conductance
    • HAWS, C., FINKBEINER, W.E., WIDDICOMBE, J.H. & WINE, J.J. (1994). CFTR in Calu-3 human airway cells: channel properties and role in cAMP-activated Cl- conductance. Am. J. Physiol., 266, L502-L512.
    • (1994) Am. J. Physiol. , vol.266
    • Haws, C.1    Finkbeiner, W.E.2    Widdicombe, J.H.3    Wine, J.J.4
  • 17
    • 0030755311 scopus 로고    scopus 로고
    • Protein kinase C and phospholipase C: Bilayer interactions and regulation
    • HURLEY, J.H. & GROBLER, J.A. (1997). Protein kinase C and phospholipase C: bilayer interactions and regulation. Curr. Opin. Struct. Biol., 7, 557-565.
    • (1997) Curr. Opin. Struct. Biol. , vol.7 , pp. 557-565
    • Hurley, J.H.1    Grobler, J.A.2
  • 18
    • 0034018802 scopus 로고    scopus 로고
    • Differential effects of UTP and ATP on ion transport in porcine tracheal epithelium
    • INGLIS, S.K., OLVER, R.E. & WILSON, S.M. (2000). Differential effects of UTP and ATP on ion transport in porcine tracheal epithelium. Br. J. Pharmacol., 130, 367-374.
    • (2000) Br. J. Pharmacol. , vol.130 , pp. 367-374
    • Inglis, S.K.1    Olver, R.E.2    Wilson, S.M.3
  • 19
    • 0035894331 scopus 로고    scopus 로고
    • Protection by tetracyclines against ion transport disruption caused by nystatin in human airway epithelial cells
    • ITO, Y., NAKAYAMA, S., SON, M., KUME, H. & YAMAKI, K. (2001). Protection by tetracyclines against ion transport disruption caused by nystatin in human airway epithelial cells. Toxicol. Appl. Pharmacol., 177, 232-237.
    • (2001) Toxicol. Appl. Pharmacol. , vol.177 , pp. 232-237
    • Ito, Y.1    Nakayama, S.2    Son, M.3    Kume, H.4    Yamaki, K.5
  • 22
    • 1642498173 scopus 로고    scopus 로고
    • Effects of fluoranthene, a polycyclic aromatic hydrocarbon, on cAMP-dependent anion secretion in human airway epithelia
    • ITO, Y., SON, M., SATO, S., OHASHI, T., KONDO, M., SHIMOKATA, K. & KUME, H. (2004b). Effects of fluoranthene, a polycyclic aromatic hydrocarbon, on cAMP-dependent anion secretion in human airway epithelia. J. Pharmacol. Exp. Ther., 308, 651-657.
    • (2004) J. Pharmacol. Exp. Ther. , vol.308 , pp. 651-657
    • Ito, Y.1    Son, M.2    Sato, S.3    Ohashi, T.4    Kondo, M.5    Shimokata, K.6    Kume, H.7
  • 23
    • 0036260974 scopus 로고    scopus 로고
    • 2 receptor agonists: A new class of medication targeted at improved mucociliary clearance
    • 2 receptor agonists: a new class of medication targeted at improved mucociliary clearance. Chest, 121, 201S-205S.
    • (2002) Chest , vol.121
    • Kellerman, D.J.1
  • 24
    • 0030008234 scopus 로고    scopus 로고
    • Analysis of the signal transduction in the induction of nitric oxide synthase by lipoteichoic acid in macrophages
    • KENGATHARAN, M., DE KIMPE, S.J. & THIEMERMANN, C. (1996). Analysis of the signal transduction in the induction of nitric oxide synthase by lipoteichoic acid in macrophages. Br. J. Pharmacol., 117, 1163-1170.
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 1163-1170
    • Kengatharan, M.1    De Kimpe, S.J.2    Thiemermann, C.3
  • 27
    • 0035184146 scopus 로고    scopus 로고
    • Protease-activated receptors in human airways: Upregulation of PAR-2 in respiratory epithelium from patients with asthma
    • KNIGHT, D.A., LIM, S., SCAFFIDI, A.K., ROCHE, N., CHUNG, K.F., STEWART, G.A. & THOMPSON, P.J. (2001). Protease-activated receptors in human airways: upregulation of PAR-2 in respiratory epithelium from patients with asthma. J. Allergy Clin. Immunol., 108, 797-803.
    • (2001) J. Allergy Clin. Immunol. , vol.108 , pp. 797-803
    • Knight, D.A.1    Lim, S.2    Scaffidi, A.K.3    Roche, N.4    Chung, K.F.5    Stewart, G.A.6    Thompson, P.J.7
  • 28
    • 0036357203 scopus 로고    scopus 로고
    • Ion transport induced by proteinase-activated receptors (PAR2) in colon and airways
    • KUNZELMANN, K., SCHREIBER, R., KONIG, J. & MALL, M. (2002). Ion transport induced by proteinase-activated receptors (PAR2) in colon and airways. Cell Biochem. Biophys., 36, 209-214.
    • (2002) Cell Biochem. Biophys. , vol.36 , pp. 209-214
    • Kunzelmann, K.1    Schreiber, R.2    Konig, J.3    Mall, M.4
  • 29
    • 0027339326 scopus 로고
    • Analysis of Gz alpha by site-directed mutagenesis. Sites and specificity of protein kinase C-dependent phosphorylation
    • LOUNSBURY, K.M., SCHLEGEL, B., PONCZ, M., BRASS, L.F. & MANNING, D.R. (1993). Analysis of Gz alpha by site-directed mutagenesis. Sites and specificity of protein kinase C-dependent phosphorylation. J. Biol. Chem., 268, 3494-3498.
    • (1993) J. Biol. Chem. , vol.268 , pp. 3494-3498
    • Lounsbury, K.M.1    Schlegel, B.2    Poncz, M.3    Brass, L.F.4    Manning, D.R.5
  • 32
    • 0024336003 scopus 로고
    • Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores
    • MINTA, A., KAO, J.P. & TSIEN, R.Y. (1989). Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores. J. Biol. Chem., 264, 8171-8178.
    • (1989) J. Biol. Chem. , vol.264 , pp. 8171-8178
    • Minta, A.1    Kao, J.P.2    Tsien, R.Y.3
  • 34
    • 0036896113 scopus 로고    scopus 로고
    • Signal transduction pathways involved in the mechanical responses to protease-activated receptors in rat colon
    • MULE, F., BAFFI, M.C., FALZONE, M. & CERRA, M.C. (2002). Signal transduction pathways involved in the mechanical responses to protease-activated receptors in rat colon. J. Pharmacol. Exp. Ther., 303, 1265-1272.
    • (2002) J. Pharmacol. Exp. Ther. , vol.303 , pp. 1265-1272
    • Mule, F.1    Baffi, M.C.2    Falzone, M.3    Cerra, M.C.4
  • 36
    • 0033631485 scopus 로고    scopus 로고
    • 2 receptor-mediated tonic contraction is attributed to an activation of phosphatidylcholine-specific phospholipase C in rabbit aortic smooth muscles
    • 2 receptor-mediated tonic contraction is attributed to an activation of phosphatidylcholine-specific phospholipase C in rabbit aortic smooth muscles. Life Sci., 66, PL71-PL76.
    • (2000) Life Sci. , vol.66
    • Nakahata, N.1    Takano, H.2    Ohizumi, Y.3
  • 37
    • 0030250127 scopus 로고    scopus 로고
    • Phosphatidylcholine hydrolysis and protein kinase C activation for intracellular signaling network
    • NAKAMURA, S. (1996). Phosphatidylcholine hydrolysis and protein kinase C activation for intracellular signaling network. J. Lipid Mediat. Cell Signal., 14, 197-202.
    • (1996) J. Lipid Mediat. Cell Signal. , vol.14 , pp. 197-202
    • Nakamura, S.1
  • 40
    • 0026742177 scopus 로고
    • Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues
    • POWIS, G., SEEWALD, M.J., GRATAS, C., MELDER, D., RIEBOW, J. & MODEST, E.J. (1992). Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues. Cancer Res., 52, 2835-2840.
    • (1992) Cancer Res. , vol.52 , pp. 2835-2840
    • Powis, G.1    Seewald, M.J.2    Gratas, C.3    Melder, D.4    Riebow, J.5    Modest, E.J.6
  • 41
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyrimidines
    • RALEVIC, V. & BURNSTOCK, G. (1998). Receptors for purines and pyrimidines. Pharmacol. Rev., 50, 413-492.
    • (1998) Pharmacol. Rev. , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 43
    • 3242798199 scopus 로고    scopus 로고
    • 2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation
    • 2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation. Exp. Mol. Med., 36, 220-225.
    • (2004) Exp. Mol. Med. , vol.36 , pp. 220-225
    • Rasheed, H.1    Saeed, S.A.2
  • 44
    • 0141891915 scopus 로고    scopus 로고
    • Synergism interaction between arachidonic acid by 5-hydroxytryptamine in human platelet aggregation is mediated through multiple signalling pathways
    • SAEED, S.A., RASHEED, H. & GILANI, A.U. (2003). Synergism interaction between arachidonic acid by 5-hydroxytryptamine in human platelet aggregation is mediated through multiple signalling pathways. Acta. Pharmacol. Sin., 24, 958-964.
    • (2003) Acta. Pharmacol. Sin. , vol.24 , pp. 958-964
    • Saeed, S.A.1    Rasheed, H.2    Gilani, A.U.3
  • 45
    • 0031903815 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide induces multiple signaling pathways in rat peritoneal mast cells
    • SEEBECK, J., KRUSE, M.L., SCHMIDT-CHOUDHURY, A., SCHMIDT-MAYER, J. & SCHMIDT, W.E. (1998). Pituitary adenylate cyclase activating polypeptide induces multiple signaling pathways in rat peritoneal mast cells. Eur. J. Pharmacol., 352, 343-350.
    • (1998) Eur. J. Pharmacol. , vol.352 , pp. 343-350
    • Seebeck, J.1    Kruse, M.L.2    Schmidt-Choudhury, A.3    Schmidt-Mayer, J.4    Schmidt, W.E.5
  • 47
    • 0034055191 scopus 로고    scopus 로고
    • Signal transduction of mucous secretion by bronchial gland cells
    • SHIMURA, S. (2000). Signal transduction of mucous secretion by bronchial gland cells. Cell Signal, 12, 271-277.
    • (2000) Cell Signal , vol.12 , pp. 271-277
    • Shimura, S.1
  • 51
    • 3042700158 scopus 로고    scopus 로고
    • 4-Chloro-benzo[F]isoquinoline (CBIQ) activates CFTR chloride channels and KCNN4 potassium channels in Calu-3 human airway epithelial cells
    • SZKOTAK, A.J., MURTHY, M., MACVINISH, L.J., DUSZYK, M. & CUTHBERT, A.W. (2004). 4-Chloro-benzo[F]isoquinoline (CBIQ) activates CFTR chloride channels and KCNN4 potassium channels in Calu-3 human airway epithelial cells. Br. J. Pharmacol., 142, 531-542.
    • (2004) Br. J. Pharmacol. , vol.142 , pp. 531-542
    • Szkotak, A.J.1    Murthy, M.2    Macvinish, L.J.3    Duszyk, M.4    Cuthbert, A.W.5
  • 52
    • 0031856402 scopus 로고    scopus 로고
    • Comparison of contractions produced by carbachol, thapsigargin and cyclopiazonic acid in the guinea-pig tracheal muscle
    • TAKEMOTO, M., TAKAGI, K., OGINO, K. & TOMITA, T. (1998). Comparison of contractions produced by carbachol, thapsigargin and cyclopiazonic acid in the guinea-pig tracheal muscle. Br. J. Pharmacol., 124, 1449-1454.
    • (1998) Br. J. Pharmacol. , vol.124 , pp. 1449-1454
    • Takemoto, M.1    Takagi, K.2    Ogino, K.3    Tomita, T.4
  • 53
    • 0028020201 scopus 로고
    • Induction of nitric oxide synthase activity in phagocytic cells inhibited by tricyclodecan-9-yl-xanthogenate (D609)
    • TSCHAIKOWSKY, K., MEISNER, M., SCHONHUBER, F. & RUGHEIMER, E. (1994). Induction of nitric oxide synthase activity in phagocytic cells inhibited by tricyclodecan-9-yl-xanthogenate (D609). Br. J. Pharmacol., 113, 664-668.
    • (1994) Br. J. Pharmacol. , vol.113 , pp. 664-668
    • Tschaikowsky, K.1    Meisner, M.2    Schonhuber, F.3    Rugheimer, E.4
  • 54
    • 0032496275 scopus 로고    scopus 로고
    • Cloning and characterization of the cDNA for human airway trypsin-like protease
    • YAMAOKA, K., MASUDA, K., OGAWA, H., TAKAGI, K., UMEMOTO, N. & YASUOKA, S. (1998). Cloning and characterization of the cDNA for human airway trypsin-like protease. J. Biol. Chem., 273, 11895-11901.
    • (1998) J. Biol. Chem. , vol.273 , pp. 11895-11901
    • Yamaoka, K.1    Masuda, K.2    Ogawa, H.3    Takagi, K.4    Umemoto, N.5    Yasuoka, S.6


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