메뉴 건너뛰기




Volumn 192, Issue 9, 2005, Pages 1577-1587

Distinct mechanisms of T cell reconstitution can be identified by estimating thymic volume in adult HIV-1 disease

(14)  Kalayjian, Robert C a,b,k   Spritzler, John c   Pu, Minya c   Landay, Alan d   Pollard, Richard B e   Stocker, Vicki f   Harthi, Lena Al d   Gross, Barry H g   Francis, Isaac R g   Fiscus, Susan A h   Tebas, Pablo i   Bosch, Ronald J c   Valcour, Victor j   Lederman, Michael M b  


Author keywords

[No Author keywords available]

Indexed keywords

EMTRICITABINE; INTERLEUKIN 7; LOPINAVIR PLUS RITONAVIR; STAVUDINE; T LYMPHOCYTE RECEPTOR;

EID: 27144445939     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/466527     Document Type: Article
Times cited : (27)

References (63)
  • 1
    • 0028902027 scopus 로고
    • Altered representation of naive and memory CD8 T cell subsets in HIV-infected children
    • Rabin RL, Roederer M, Maldonado Y, Petru A, Herzenberg LA. Altered representation of naive and memory CD8 T cell subsets in HIV-infected children. J Clin Invest 1995; 95:2054-60.
    • (1995) J Clin Invest , vol.95 , pp. 2054-2060
    • Rabin, R.L.1    Roederer, M.2    Maldonado, Y.3    Petru, A.4    Herzenberg, L.A.5
  • 3
    • 0034304597 scopus 로고    scopus 로고
    • T cell depletion in HIV-1 infection: How CD4+ T cells go out of stock
    • Hazenberg MD, Hamann D, Schuitemaker H, Miedema F. T cell depletion in HIV-1 infection: how CD4+ T cells go out of stock. Nat Immunol 2000; 1:285-9.
    • (2000) Nat Immunol , vol.1 , pp. 285-289
    • Hazenberg, M.D.1    Hamann, D.2    Schuitemaker, H.3    Miedema, F.4
  • 5
    • 0024317522 scopus 로고
    • A prospective study of human immunodeficiency virus type 1 infection and the development of AIDS in subjects with hemophilia
    • Goedert JJ, Kessler CM, Aledort LM, et al. A prospective study of human immunodeficiency virus type 1 infection and the development of AIDS in subjects with hemophilia. N Engl J Med 1989; 321:1141-8.
    • (1989) N Engl J Med , vol.321 , pp. 1141-1148
    • Goedert, J.J.1    Kessler, C.M.2    Aledort, L.M.3
  • 6
    • 0025950082 scopus 로고
    • More rapid progression to AIDS in older HIV-infected people: The role of CD4+ T-cell counts
    • Phillips AN, Lee CA, Elford J, et al. More rapid progression to AIDS in older HIV-infected people: the role of CD4+ T-cell counts. J Acquir Immune Defic Syndr 1991;4:970-5.
    • (1991) J Acquir Immune Defic Syndr , vol.4 , pp. 970-975
    • Phillips, A.N.1    Lee, C.A.2    Elford, J.3
  • 7
    • 0026756378 scopus 로고
    • Predictors of HIV-1 disease progression in early- and late-stage patients: The U.S. Army Natural History Cohort
    • Military Medical Consortium for Applied Retrovirology
    • Gardner LI Jr, Brundage JF, McNeil JG, et al. Predictors of HIV-1 disease progression in early- and late-stage patients: the U.S. Army Natural History Cohort. Military Medical Consortium for Applied Retrovirology. J Acquir Immune Defic Syndr 1992; 5:782-93.
    • (1992) J Acquir Immune Defic Syndr , vol.5 , pp. 782-793
    • Gardner Jr., L.I.1    Brundage, J.F.2    McNeil, J.G.3
  • 8
    • 0028337301 scopus 로고
    • Effect of age at seroconversion on the natural AIDS incubation distribution. Multicenter Hemophilia Cohort Study and the International Registry of Seroconverters
    • Rosenberg PS, Goedert JJ, Biggar RJ. Effect of age at seroconversion on the natural AIDS incubation distribution. Multicenter Hemophilia Cohort Study and the International Registry of Seroconverters. AIDS 1994; 8:803-10.
    • (1994) AIDS , vol.8 , pp. 803-810
    • Rosenberg, P.S.1    Goedert, J.J.2    Biggar, R.J.3
  • 9
    • 0028922669 scopus 로고
    • Multivariate models for predicting progression to AIDS and survival in human immunodeficiency virus-infected persons
    • Blatt SP, McCarthy WF, Bucko-Krasnicka B, et al. Multivariate models for predicting progression to AIDS and survival in human immunodeficiency virus-infected persons. J Infect Dis 1995; 171:837-44.
    • (1995) J Infect Dis , vol.171 , pp. 837-844
    • Blatt, S.P.1    McCarthy, W.F.2    Bucko-Krasnicka, B.3
  • 10
    • 0029135361 scopus 로고
    • Human immunodeficiency virus type 1 infection; relationship of risk group and age to rate of progression to AIDS
    • Transfusion Safety Study Group
    • Operskalski EA, Stram DO, Lee H, et al. Human immunodeficiency virus type 1 infection; relationship of risk group and age to rate of progression to AIDS. Transfusion Safety Study Group. J Infect Dis 1995; 172:648-55.
    • (1995) J Infect Dis , vol.172 , pp. 648-655
    • Operskalski, E.A.1    Stram, D.O.2    Lee, H.3
  • 11
    • 0029927283 scopus 로고    scopus 로고
    • Importance of age at infection with HIV-1 for survival and development of AIDS in UK haemophilia population
    • UK Haemophilia Centre Directors' Organisation
    • Darby SC, Ewart DW, Giangrande PL, Spooner RJ, Rizza CR. Importance of age at infection with HIV-1 for survival and development of AIDS in UK haemophilia population. UK Haemophilia Centre Directors' Organisation. Lancet 1996; 347:1573-9.
    • (1996) Lancet , vol.347 , pp. 1573-1579
    • Darby, S.C.1    Ewart, D.W.2    Giangrande, P.L.3    Spooner, R.J.4    Rizza, C.R.5
  • 13
    • 0030035583 scopus 로고    scopus 로고
    • The aging immune system: Primer and prospectus
    • Miller RA. The aging immune system: primer and prospectus. Science 1996; 273:70-4.
    • (1996) Science , vol.273 , pp. 70-74
    • Miller, R.A.1
  • 14
    • 0034194058 scopus 로고    scopus 로고
    • + T cells provides new insights on immunodeficiency in aging
    • + T cells provides new insights on immunodeficiency in aging. Blood 2000; 95:2860-8.
    • (2000) Blood , vol.95 , pp. 2860-2868
    • Fagnoni, F.F.1    Vescovini, R.2    Passeri, G.3
  • 15
    • 0034492842 scopus 로고    scopus 로고
    • Cellular restoration in HIV infected persons treated with abacavir and a protease inhibitor: Age inversely predicts naive CD4 cell count increase
    • Lederman MM, McKinnis R, Kelleher D, et al. Cellular restoration in HIV infected persons treated with abacavir and a protease inhibitor: age inversely predicts naive CD4 cell count increase. AIDS 2000; 14: 2635-42.
    • (2000) AIDS , vol.14 , pp. 2635-2642
    • Lederman, M.M.1    McKinnis, R.2    Kelleher, D.3
  • 16
    • 0037159921 scopus 로고    scopus 로고
    • Reconstitution of naive T cells during antiretroviral treatment of HIV-infected adults is dependent on age
    • Cohen Stuart J, Hamann D, Borleffs J, et al. Reconstitution of naive T cells during antiretroviral treatment of HIV-infected adults is dependent on age. AIDS 2002; 16:2263-6.
    • (2002) AIDS , vol.16 , pp. 2263-2266
    • Cohen Stuart, J.1    Hamann, D.2    Borleffs, J.3
  • 17
    • 17444372347 scopus 로고    scopus 로고
    • Changes in thymic function with age and during the treatment of HIV infection
    • Douek DC, McFarland RD, Reiser PH, et al. Changes in thymic function with age and during the treatment of HIV infection. Nature 1998; 396:690-5.
    • (1998) Nature , vol.396 , pp. 690-695
    • Douek, D.C.1    McFarland, R.D.2    Reiser, P.H.3
  • 18
    • 0035964691 scopus 로고    scopus 로고
    • Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function
    • Teixeira L, Valdez H, McCune JM, et al. Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function. AIDS 2001; 15:1749-56.
    • (2001) AIDS , vol.15 , pp. 1749-1756
    • Teixeira, L.1    Valdez, H.2    McCune, J.M.3
  • 19
    • 0032104145 scopus 로고    scopus 로고
    • High prevalence of thymic tissue in adults with human immunodeficiency virus-1 infection
    • McCune JM, Loftus R, Schmidt DK, et al. High prevalence of thymic tissue in adults with human immunodeficiency virus-1 infection. J Clin Invest 1998; 101:2301-8.
    • (1998) J Clin Invest , vol.101 , pp. 2301-2308
    • McCune, J.M.1    Loftus, R.2    Schmidt, D.K.3
  • 20
    • 0033958888 scopus 로고    scopus 로고
    • Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapy
    • Smith KY, Valdez H, Landay A, et al. Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapy. J Infect Dis 2000; 181:141-7.
    • (2000) J Infect Dis , vol.181 , pp. 141-147
    • Smith, K.Y.1    Valdez, H.2    Landay, A.3
  • 21
    • 0034096189 scopus 로고    scopus 로고
    • Early immune reconstitution after potent antiretroviral therapy in HIV-infected children correlates with the increase in thymus volume
    • Vigano A, Vella S, Saresella M, et al. Early immune reconstitution after potent antiretroviral therapy in HIV-infected children correlates with the increase in thymus volume. AIDS 2000; 14:251-61.
    • (2000) AIDS , vol.14 , pp. 251-261
    • Vigano, A.1    Vella, S.2    Saresella, M.3
  • 22
    • 0036681857 scopus 로고    scopus 로고
    • Evidence of thymic function in heavily antiretroviral-treated human immunodeficiency virus type 1-infected adults with long-term virologic treatment failure
    • Delgado J, Leal M, Ruiz-Mateos E, et al. Evidence of thymic function in heavily antiretroviral-treated human immunodeficiency virus type 1-infected adults with long-term virologic treatment failure. J Infect Dis 2002; 186:410-4.
    • (2002) J Infect Dis , vol.186 , pp. 410-414
    • Delgado, J.1    Leal, M.2    Ruiz-Mateos, E.3
  • 23
    • 0037093057 scopus 로고    scopus 로고
    • T-cell repopulation and thymic volume in HIV-1-infected adult patients after highly active antiretroviral therapy
    • Franco JM, Rubio A, Martinez-Moya M, et al. T-cell repopulation and thymic volume in HIV-1-infected adult patients after highly active antiretroviral therapy. Blood 2002; 99:3702-6.
    • (2002) Blood , vol.99 , pp. 3702-3706
    • Franco, J.M.1    Rubio, A.2    Martinez-Moya, M.3
  • 24
    • 0036605699 scopus 로고    scopus 로고
    • Association between larger thymic size and higher thymic output in human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy
    • Kolte L, Dreves A-M, Ersboll AK, et al. Association between larger thymic size and higher thymic output in human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy. J Infect Dis 2002; 185:1578-85.
    • (2002) J Infect Dis , vol.185 , pp. 1578-1585
    • Kolte, L.1    Dreves, A.-M.2    Ersboll, A.K.3
  • 25
    • 10344246581 scopus 로고    scopus 로고
    • HIV infection rapidly induces and maintains a substantial suppression of thymocyte proliferation
    • Dion ML, Poulin JF, Bordi R, et al. HIV infection rapidly induces and maintains a substantial suppression of thymocyte proliferation. Immunity 2004; 21:757-68.
    • (2004) Immunity , vol.21 , pp. 757-768
    • Dion, M.L.1    Poulin, J.F.2    Bordi, R.3
  • 26
    • 0031849216 scopus 로고    scopus 로고
    • Peripheral expansion of preexisting mature T cells is an important means of CD4+ T-cell regeneration HIV-infected adults
    • Walker RE, Carter CS, Muul L, et al. Peripheral expansion of preexisting mature T cells is an important means of CD4+ T-cell regeneration HIV-infected adults. Nat Med 1998; 4:852-6.
    • (1998) Nat Med , vol.4 , pp. 852-856
    • Walker, R.E.1    Carter, C.S.2    Muul, L.3
  • 27
    • 0033557266 scopus 로고    scopus 로고
    • Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection
    • Haynes BF, Hale LP, Weinhold KJ, et al. Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection. J Clin Invest 1999; 103:921.
    • (1999) J Clin Invest , vol.103 , pp. 921
    • Haynes, B.F.1    Hale, L.P.2    Weinhold, K.J.3
  • 28
    • 17444379333 scopus 로고    scopus 로고
    • Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans
    • Hellerstein M, Hanley MB, Cesar D, et al. Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans. Nat Med 1999; 5:83-9.
    • (1999) Nat Med , vol.5 , pp. 83-89
    • Hellerstein, M.1    Hanley, M.B.2    Cesar, D.3
  • 29
    • 0035905463 scopus 로고    scopus 로고
    • Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV
    • Kovacs JA, Lempicki RA, Sidorov IA, et al. Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV. J Exp Med 2001; 194:1731-41.
    • (2001) J Exp Med , vol.194 , pp. 1731-1741
    • Kovacs, J.A.1    Lempicki, R.A.2    Sidorov, I.A.3
  • 30
    • 0035169609 scopus 로고    scopus 로고
    • Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy
    • Mohri H, Perekon AS, Tung K, et al. Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy. J Exp Med 2001; 194:1277-87.
    • (2001) J Exp Med , vol.194 , pp. 1277-1287
    • Mohri, H.1    Perekon, A.S.2    Tung, K.3
  • 32
    • 18744435046 scopus 로고    scopus 로고
    • Restoration of T-cell homeostasis after T-cell depletion
    • Mackall CL, Hakim FT, Gress RE. Restoration of T-cell homeostasis after T-cell depletion. Semin Immunol 1997; 9:339-46.
    • (1997) Semin Immunol , vol.9 , pp. 339-346
    • Mackall, C.L.1    Hakim, F.T.2    Gress, R.E.3
  • 34
    • 27144519696 scopus 로고    scopus 로고
    • The Adult AIDS Clinical Trials Group Immunology. Consensus methods. Available at: http://aactg.s-3.com/immmeth.htm/. Accessed 6 April 2004.
    • Consensus Methods
  • 35
    • 0008916909 scopus 로고    scopus 로고
    • HIV infection perturbs DNA content of lymphoid cells: Partial correction after "suppression" of virus replication
    • Patki AH, Purvis SF, Valdez H, et al. HIV infection perturbs DNA content of lymphoid cells: partial correction after "suppression" of virus replication. AIDS 1999; 13:1177-85.
    • (1999) AIDS , vol.13 , pp. 1177-1185
    • Patki, A.H.1    Purvis, S.F.2    Valdez, H.3
  • 36
    • 10744222905 scopus 로고    scopus 로고
    • Evaluation of the impact of highly active antiretroviral therapy on immune recovery in antiretroviral naive patients
    • Al-Harthi L, Voris J, Patterson BK, et al. Evaluation of the impact of highly active antiretroviral therapy on immune recovery in antiretroviral naive patients. HIV Med 2004; 5:55-65.
    • (2004) HIV Med , vol.5 , pp. 55-65
    • Al-Harthi, L.1    Voris, J.2    Patterson, B.K.3
  • 37
    • 7744222333 scopus 로고    scopus 로고
    • Immunologic and clinical responses to highly active antiretroviral therapy over 50 years of age: Results from the French Hospital Database on HIV
    • Grabar S, Kousignian I, Sobel A, et al. Immunologic and clinical responses to highly active antiretroviral therapy over 50 years of age: results from the French Hospital Database on HIV. AIDS 2004; 18: 2029-38.
    • (2004) AIDS , vol.18 , pp. 2029-2038
    • Grabar, S.1    Kousignian, I.2    Sobel, A.3
  • 38
    • 0036604224 scopus 로고    scopus 로고
    • Clinical experience with human immunodeficiency virus-infected older patients in the era of effective antiretroviral therapy
    • Grimes RM, Otiniano ME, Rodriguez-Barradas MC, Lai D. Clinical experience with human immunodeficiency virus-infected older patients in the era of effective antiretroviral therapy. Clin Infect Dis 2002; 34:1530-3.
    • (2002) Clin Infect Dis , vol.34 , pp. 1530-1533
    • Grimes, R.M.1    Otiniano, M.E.2    Rodriguez-Barradas, M.C.3    Lai, D.4
  • 39
    • 0037439528 scopus 로고    scopus 로고
    • Greater effect of highly active antiretroviral therapy on survival in people aged 3=50 years compared with younger people in an urban observational cohort
    • Perez JL, Moore RD. Greater effect of highly active antiretroviral therapy on survival in people aged 3=50 years compared with younger people in an urban observational cohort. Clin Infect Dis 2003;36:212-8.
    • (2003) Clin Infect Dis , vol.36 , pp. 212-218
    • Perez, J.L.1    Moore, R.D.2
  • 41
    • 0037016424 scopus 로고    scopus 로고
    • Predictors of virological rebound in HIV-1-infected patients initiating a protease inhibitor-containing regimen
    • Le Moing V, Chene G, Carrieri MP, et al. Predictors of virological rebound in HIV-1-infected patients initiating a protease inhibitor-containing regimen. AIDS 2002; 16:21-9.
    • (2002) AIDS , vol.16 , pp. 21-29
    • Le Moing, V.1    Chene, G.2    Carrieri, M.P.3
  • 42
    • 0030754129 scopus 로고    scopus 로고
    • Essential role of the thymus to reconstitute naive (CD45RA+) T-helper cells after human allogeneic bone marrow transplantation
    • Heitger A, Neu N, Kern H, et al. Essential role of the thymus to reconstitute naive (CD45RA+) T-helper cells after human allogeneic bone marrow transplantation. Blood 1997; 90:850-7.
    • (1997) Blood , vol.90 , pp. 850-857
    • Heitger, A.1    Neu, N.2    Kern, H.3
  • 43
    • 0037128660 scopus 로고    scopus 로고
    • Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood
    • Kimmig S, Przybylski GK, Schmidt CA, et al. Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood. J Exp Med 2002; 195:789-94.
    • (2002) J Exp Med , vol.195 , pp. 789-794
    • Kimmig, S.1    Przybylski, G.K.2    Schmidt, C.A.3
  • 44
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
    • Schluns KS, Kieper WC, Jameson SC, Lefrancois L. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat Immunol 2000; 1:426-32.
    • (2000) Nat Immunol , vol.1 , pp. 426-432
    • Schluns, K.S.1    Kieper, W.C.2    Jameson, S.C.3    Lefrancois, L.4
  • 45
    • 0035282766 scopus 로고    scopus 로고
    • IL-7 increases both thymic-dependent and thymic-independent T-cell regeneration after bone marrow transplantation
    • Mackall CL, Fry TJ, Bare C, Morgan P, Galbraith A, Gress RE. IL-7 increases both thymic-dependent and thymic-independent T-cell regeneration after bone marrow transplantation. Blood 2001; 97:1491-7.
    • (2001) Blood , vol.97 , pp. 1491-1497
    • Mackall, C.L.1    Fry, T.J.2    Bare, C.3    Morgan, P.4    Galbraith, A.5    Gress, R.E.6
  • 46
    • 0035902513 scopus 로고    scopus 로고
    • IL-7 is critical for homeostatic proliferation and survival of naive T cells
    • Tan JT, Dudl E, LeRoy E, et al. IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci USA 2001; 98:8732-7.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8732-8737
    • Tan, J.T.1    Dudl, E.2    LeRoy, E.3
  • 47
    • 0037443464 scopus 로고    scopus 로고
    • IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected non-human primates
    • Fry TJ, Moniuszko M, Creekmore S, et al. IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected non-human primates. Blood 2003; 101:2294-9.
    • (2003) Blood , vol.101 , pp. 2294-2299
    • Fry, T.J.1    Moniuszko, M.2    Creekmore, S.3
  • 48
    • 0035874499 scopus 로고    scopus 로고
    • A potential role for interleukin-7 in T-cell homeostasis
    • Fry TJ, Connick E, Falloon J, et al. A potential role for interleukin-7 in T-cell homeostasis. Blood 2001; 97:2983-90.
    • (2001) Blood , vol.97 , pp. 2983-2990
    • Fry, T.J.1    Connick, E.2    Falloon, J.3
  • 49
    • 0035138982 scopus 로고    scopus 로고
    • Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: Implications for T-cell homeostasis
    • Napolitano LA, Grant RM, Deeks SG, et al. Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis. Nat Med 2001; 7:73-9.
    • (2001) Nat Med , vol.7 , pp. 73-79
    • Napolitano, L.A.1    Grant, R.M.2    Deeks, S.G.3
  • 50
    • 0035172204 scopus 로고    scopus 로고
    • IL-7 enhances the responsiveness of human T cells that develop in the bone marrow of athymic mice
    • Tsark EC, Dao MA, Wang X, Weinberg K, Nolta JA. IL-7 enhances the responsiveness of human T cells that develop in the bone marrow of athymic mice. J Immunol 2001; 166:170-81.
    • (2001) J Immunol , vol.166 , pp. 170-181
    • Tsark, E.C.1    Dao, M.A.2    Wang, X.3    Weinberg, K.4    Nolta, J.A.5
  • 51
    • 0038417311 scopus 로고    scopus 로고
    • Incomplete CD4 T cell recovery in HIV-1 infection after 12 months of highly active antiretroviral therapy is associated with ongoing increased CD4 T cell activation and turnover
    • Anthony KB, Voder C, Metcalf JA, et al. Incomplete CD4 T cell recovery in HIV-1 infection after 12 months of highly active antiretroviral therapy is associated with ongoing increased CD4 T cell activation and turnover. J Acquir Immune Defic Syndr 2003; 33:125-33.
    • (2003) J Acquir Immune Defic Syndr , vol.33 , pp. 125-133
    • Anthony, K.B.1    Voder, C.2    Metcalf, J.A.3
  • 52
    • 0038701685 scopus 로고    scopus 로고
    • + T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy
    • + T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy. J Infect Dis 2003; 187:1534-43.
    • (2003) J Infect Dis , vol.187 , pp. 1534-1543
    • Hunt, P.W.1    Martin, J.N.2    Sinclair, E.3
  • 53
    • 2442655107 scopus 로고    scopus 로고
    • Immunophenotypic markers and antiretroviral therapy (IMART): T cell activation and maturation help predict treatment response
    • Mildvan D, Bosch RJ, Kim RS, et al. Immunophenotypic markers and antiretroviral therapy (IMART): T cell activation and maturation help predict treatment response. J Infect Dis 2004; 189:1811-20.
    • (2004) J Infect Dis , vol.189 , pp. 1811-1820
    • Mildvan, D.1    Bosch, R.J.2    Kim, R.S.3
  • 54
    • 0031882434 scopus 로고    scopus 로고
    • Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation
    • Pakker NG, Notermans DW, de Boer RJ, et al. Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation. Nat Med 1998; 4:208-14.
    • (1998) Nat Med , vol.4 , pp. 208-214
    • Pakker, N.G.1    Notermans, D.W.2    De Boer, R.J.3
  • 55
    • 0033028912 scopus 로고    scopus 로고
    • Immune clearance of HIV type 1 replication-active cells: A model of two patterns of steady state HIV infection
    • Bucy RP. Immune clearance of HIV type 1 replication-active cells: a model of two patterns of steady state HIV infection. AIDS Res Hum Retroviruses 1999; 15:223-7.
    • (1999) AIDS Res Hum Retroviruses , vol.15 , pp. 223-227
    • Bucy, R.P.1
  • 56
    • 0033831175 scopus 로고    scopus 로고
    • Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection
    • Hazenberg MD, Otto SA, Cohen Stuart JW, et al. Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection. Nat Med 2000; 6:1036-42.
    • (2000) Nat Med , vol.6 , pp. 1036-1042
    • Hazenberg, M.D.1    Otto, S.A.2    Cohen Stuart, J.W.3
  • 57
    • 0030833497 scopus 로고    scopus 로고
    • Constraints on CD4 recovery postchemotherapy in adults: Thymic insufficiency and apoptotic decline of expanded peripheral CD4 cells
    • Hakim FT, Cepeda R, Kaimei S, et al. Constraints on CD4 recovery postchemotherapy in adults: thymic insufficiency and apoptotic decline of expanded peripheral CD4 cells. Blood 1997; 90:3789-98.
    • (1997) Blood , vol.90 , pp. 3789-3798
    • Hakim, F.T.1    Cepeda, R.2    Kaimei, S.3
  • 58
    • 0029034517 scopus 로고
    • Analysis of apoptosis in lymph nodes of HIV-infected persons: Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden
    • Muro-Cacho CA, Pantaleo G, Fauci AS. Analysis of apoptosis in lymph nodes of HIV-infected persons: intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden. J Immunol 1995; 154:5555-66.
    • (1995) J Immunol , vol.154 , pp. 5555-5566
    • Muro-Cacho, C.A.1    Pantaleo, G.2    Fauci, A.S.3
  • 60
    • 0038205357 scopus 로고    scopus 로고
    • T cells containing T cell receptor excision circles are inversely related to HIV replication and are selectively and rapidly released into circulation with antiretroviral treatment
    • Diaz M, Douek DC, Valdez H, et al. T cells containing T cell receptor excision circles are inversely related to HIV replication and are selectively and rapidly released into circulation with antiretroviral treatment. AIDS 2003; 17:1145-9.
    • (2003) AIDS , vol.17 , pp. 1145-1149
    • Diaz, M.1    Douek, D.C.2    Valdez, H.3
  • 61
    • 0035341526 scopus 로고    scopus 로고
    • Homeostasis of naive and memory T cell subpopulations in peripheral blood and lymphoid tissues in the context of human immunodeficiency virus infection
    • Nokta MA, Li X-D, Nichols J, Pou A, Asmuth D, Pollard RB. Homeostasis of naive and memory T cell subpopulations in peripheral blood and lymphoid tissues in the context of human immunodeficiency virus infection. J Infect Dis 2001; 183:1336-42.
    • (2001) J Infect Dis , vol.183 , pp. 1336-1342
    • Nokta, M.A.1    Li, X.-D.2    Nichols, J.3    Pou, A.4    Asmuth, D.5    Pollard, R.B.6
  • 62
    • 3142546949 scopus 로고    scopus 로고
    • De novo T-cell generation in patients at different ages and stages of HIV-1 disease
    • Nobile M, Correa R, Borghans JA, et al. De novo T-cell generation in patients at different ages and stages of HIV-1 disease. Blood 2004; 104; 470-7.
    • (2004) Blood , vol.104 , pp. 470-477
    • Nobile, M.1    Correa, R.2    Borghans, J.A.3
  • 63
    • 0028850465 scopus 로고
    • Human naive and memory T lymphocytes differ in telomeric length and replicative potential
    • Weng NP, Levine BL, June CH, Hodes RJ. Human naive and memory T lymphocytes differ in telomeric length and replicative potential. Proc Natl Acad Sci USA 1995; 92:11091-4.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11091-11094
    • Weng, N.P.1    Levine, B.L.2    June, C.H.3    Hodes, R.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.