Signaling underlying pulsatile insulin secretion

Upsala Journal of Medical Sciences

Volumn 105, Issue 2, 2000, Pages 35-51

  Gylfe, Erik ^a,b   Ahmed, Meftun ^a   Bergsten, Peter ^a   Dansk, Heléne ^a   Dyachok, Oleg ^a   Eberhardson, Michael ^a   Grapengiesser, Eva ^a   Hellman, Bo ^a   Lin, Jian Man ^a   Sundsten, Tea ^a   Tengholm, Anders ^a   Vieira, Elaine ^a   Westerlund, Johanna ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b Falun Central Hospital   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

ANIMAL; CALCIUM SIGNALING; HUMAN; METABOLISM; PANCREAS ISLET; REVIEW; SECRETION;

ANIMALS; CALCIUM SIGNALING; HUMANS; INSULIN; ISLETS OF LANGERHANS;

EID: 0034566967     PISSN: 03009734     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. + conductance in glucose-stimulated pancreatic β-cells. Nature 353:849-852, 1991.
2. Andreu, E., Soria, B. & Sanchez-Andres, J. V.: Oscillations of gap junction electrical coupling in the mouse pancreatic islets of Langerhans. J Physiol (London) 498:753-761, 1997.
3. Ashcroft, F. M. & Rorsman, P.: Electrophysiology of the pancreatic β-cell. Prog Biophys Mol Biol 54:87-143, 1989.
4. + channels: a link between β-cell metabolism and insulin secretion. Biochem Soc Trans 18:109-111, 1990.
5. Barbosa, R. M., Silva, A. M., Tomé, A. R., Stamford, J. A., Santos, R. M. & Rosario, L. M.: Real time electrochemical detection of 5-HT/insulin secretion from single pancreatic islets: Effect of glucose and K+ depolarization. Biochem Biophys Res Commun 228:100-104, 1996.
6. Barbosa, R. M., Silva, A. M., Tomé, A. R., Stamford, J. A., Santos, R. M. & Rosario, L. M.: Control of pulsatile 5-HT/insulin secretion from single mouse pancreatic islets by intracellular calcium dynamics. J Physiol (London) 510:135-143, 1998.
7. 2+ in pancreatic islets correspond to pulsatile insulin release. Am J Physiol 268:E282-E287, 1995.
8. 2+ and insulin release in glucose-stimulated pancreatic islets. J Biol Chem 269:8749-8753, 1994.
9. Bergsten, P. & Hellman, B.: Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets. Diabetes 42:670-674, 1993.
10. Bergsten, P. & Hellman, B.: Glucose-induced cycles of insulin release can be resolved into distinct periods of secretory activity. Biochem Biophys Res Commun 192:1182-1188, 1993.
11. 2+ signals in pancreatic islet cells. Diabetes 48:1971-1978, 1999.
12. Bratusch-Marrain, P. R., Komjati, M. & Waldhäusl, W. K.: Efficacy of pulsatile versus continuous insulin administration on hepatic glucose production and glucose utilization in type I diabetic humans. Diabetes 35:922-926, 1986.
13. Chap, Z., Ishida, T., Chou, J., Hartley, C. J., Entman, M. L., Brandenburg, D., Jones, R. H. & Field, J. B.: First-pass hepatic extraction and metabolic effects of insulin and insulin analogues. Am J Physiol 252:E209-E217, 1987.
14. 2+ in mouse pancreatic βcells. J Physiol (London) 485:607-617, 1995.
15. Cook, D. L.: Isolated islets of Langerhans have slow oscillations of electrical activity. Metabolism 32:681-685, 1983.