Apoptotic speck protein-like, a highly homologous protein to apoptotic speck protein in the pyrin domain, is silenced by DNA methylation and induces apoptosis in human hepatocellular carcinoma

Cancer Research

Volumn 64, Issue 15, 2004, Pages 5172-5177

  Kubo, Takahiko ^a   Yamamoto, Junji ^a   Shikauchi, Yuko ^a   Niwa, Yasuharu ^a   Matsubara, Kenichi ^b   Yoshikawa, Hirohide ^a  

^a CANCER INSTITUTE   (Japan)

^b DNA CHIP RESEARCH INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; APOPTOSIS INDUCING FACTOR; APOPTOTIC SPECK PROTEIN; CASPASE 5; DNA; LIPOCORTIN 5; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; ASCL GENE; BRAIN; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMETHYLATION; DNA METHYLATION; GENE; GENE IDENTIFICATION; GENE SILENCING; HUMAN; HUMAN CELL; LIVER; LIVER CELL CARCINOMA; METHYLATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; SPLEEN; STATISTICAL SIGNIFICANCE;

AMINO ACID SEQUENCE; ANNEXIN A5; APOPTOSIS; AZACITIDINE; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CASPASES; CYTOSKELETAL PROTEINS; DNA METHYLATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; LIVER NEOPLASMS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TUMOR CELLS, CULTURED;

EID: 3442885926     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-3314     Document Type: Article

References (18)

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