Benzofuroindole analogues as potent BKCa channel openers

ChemBioChem

Volumn 6, Issue 10, 2005, Pages 1745-1748

  Gormemis, Ahmet E ^a   Ha, Tal Soo ^a   Im, Isak ^a   Jung, Kwan Young ^a   Lee, Ju Yeon ^a   Park, Chul Seung ^a   Kim, Yong Chul ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

Benzofuroindole; Drug design; Ion channels; Opener; Outside out patches

Indexed keywords

3 (5 CHLORO 2 METHOXYPHENYL) 3 FLUORO 2,3 DIHYDRO 6 TRIFLUOROMETHYL 1H INDOL 2 ONE; BENZOFUROINDOLE; CALCIUM ACTIVATED POTASSIUM CHANNEL; INDOLE DERIVATIVE; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; POTASSIUM ION; QUINOLINONE; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE POTENTIAL; CEREBROVASCULAR ACCIDENT; CLINICAL TRIAL; CYCLIZATION; DRUG ACTIVITY; DRUG EFFECT; DRUG SUBSTITUTION; HUMAN; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; BENZOFURANS; CALCIUM; FEMALE; INDOLES; MEMBRANE POTENTIALS; MUSCLE, SMOOTH, VASCULAR; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 26944503067     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200400448     Document Type: Article

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