Synthesis and potassium channel opening activity of substituted 10H-benzo[4,5]furo[3,2-b]indole- and 5,10-dihydro-indeno[1,2-b]indole-1-carboxylic acids

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 16, 2001, Pages 2093-2097

  Butera, John A ^a   Antane, Schuyler A ^a   Hirth, Bradford ^a   Lennox, Joseph R ^a   Sheldon, Jeffrey H ^b   Norton, N Wesley ^b   Warga, Dawn ^b   Argentieri, Thomas M ^b  

^a PFIZER INC   (United States)

^b WYETH AYERST RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

10H BENZO[4,5]FURO[3,2 B]INDOLE; 5,10 DIHYDROINDENO[1,2 B]INDOLE 1 CARBOXYLIC ACID DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; IBERIOTOXIN; INDOLE DERIVATIVE; POTASSIUM CHANNEL; SPASMOLYTIC AGENT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BLADDER; CALCIUM CONDUCTANCE; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DETRUSOR MUSCLE; ELECTROPHYSIOLOGY; HYPERPOLARIZATION; NONHUMAN; RAT; SMOOTH MUSCLE; URGE INCONTINENCE;

ANIMALS; CARBOXYLIC ACIDS; INDOLES; MUSCLES; PARASYMPATHOLYTICS; POTASSIUM CHANNELS; RATS;

EID: 0035921067     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00385-7     Document Type: Article

References (29)