Theophylline attenuates Ca 2+ sensitivity and modulates BK channels in porcine tracheal smooth muscle

British Journal of Pharmacology

Volumn 140, Issue 5, 2003, Pages 939-947

  Ise, Shinji ^a   Nishimura, Junji ^a   Hirano, Katsuya ^a   Hara, Nobuyuki ^a   Kanaide, Hideo ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Ca 2+ sensitivity; cAMP; cGMP; Iberiotoxin; Intracellular Ca 2+ concentration; Large conductance Ca 2+ activated K + channel; Porcine tracheal smooth muscle; Theophylline

Indexed keywords

ALPHA TOXIN; CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM ION; CARBACHOL; CYCLIC AMP; CYCLIC GMP; FURA 2; IBERIOTOXIN; POTASSIUM ION; THEOPHYLLINE; CALCIUM; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; CELL PERMEABILIZATION; CONTROLLED STUDY; DEPOLARIZATION; DRUG ACTIVITY; DRUG INHIBITION; EXTRACELLULAR CALCIUM; FLUOROMETRY; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; SMOOTH MUSCLE TONE; SWINE; TRACHEA MUSCLE; ANIMAL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; IN VITRO STUDY; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY; SMOOTH MUSCLE; TRACHEA;

ANIMALS; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MUSCLE CONTRACTION; MUSCLE, SMOOTH; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; SWINE; THEOPHYLLINE; TRACHEA;

EID: 0344873144     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705508     Document Type: Article

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