-
1
-
-
0034600036
-
Toxicologic evidence of developmental neurotoxicity of environmental chemicals
-
Andersen, H. R., Nielsen, J. B., and Grandjean, P. (2000). Toxicologic evidence of developmental neurotoxicity of environmental chemicals. Toxicology 144, 121-127.
-
(2000)
Toxicology
, vol.144
, pp. 121-127
-
-
Andersen, H.R.1
Nielsen, J.B.2
Grandjean, P.3
-
2
-
-
0037924433
-
Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene
-
Bachman, K. E., Park, B. H., Rhee, I., Rajagopalan, H., Herman, J. G., Baylin, S. B., Kinzler, K. W., and Vogelstein, B. (2003). Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene. Cancer Cell 3, 89-95.
-
(2003)
Cancer Cell
, vol.3
, pp. 89-95
-
-
Bachman, K.E.1
Park, B.H.2
Rhee, I.3
Rajagopalan, H.4
Herman, J.G.5
Baylin, S.B.6
Kinzler, K.W.7
Vogelstein, B.8
-
3
-
-
0033858044
-
Effect of chlorinated hydrocarbons on expression of cytochrome P450 1A1, 1A2 and 1B1 and 2-and 4-hydroxylation of 17β-estradiol in female Sprague-Dawley rats
-
Badawi, A. F., Cavalieri, E. L., and Rogan, E. G. (2000). Effect of chlorinated hydrocarbons on expression of cytochrome P450 1A1, 1A2 and 1B1 and 2-and 4-hydroxylation of 17β-estradiol in female Sprague-Dawley rats. Carcinogenesis 21, 1593-1599.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1593-1599
-
-
Badawi, A.F.1
Cavalieri, E.L.2
Rogan, E.G.3
-
4
-
-
0142179253
-
Membrane receptors for oestrogen in the brain
-
Beyer, C., Pawlak, J., and Karolczak, M. (2003). Membrane receptors for oestrogen in the brain. J. Neurochem. 87, 545-550.
-
(2003)
J. Neurochem.
, vol.87
, pp. 545-550
-
-
Beyer, C.1
Pawlak, J.2
Karolczak, M.3
-
5
-
-
1842817557
-
Perturbation of epigenetic status by toxicants
-
Bombail, V., Moggs, J. G., and Orphanides, G. (2004). Perturbation of epigenetic status by toxicants. Toxicol. Lett. 149, 51-58.
-
(2004)
Toxicol. Lett.
, vol.149
, pp. 51-58
-
-
Bombail, V.1
Moggs, J.G.2
Orphanides, G.3
-
6
-
-
0027323122
-
Minireview. Pathologic effect of estradiol on the hypothalamus
-
Brawer, J. R., Beaudet, A., Desjardins, G. C., and Schipper, H. M. (1993). Minireview. Pathologic effect of estradiol on the hypothalamus. Biol. Reprod. 49, 647-652.
-
(1993)
Biol. Reprod.
, vol.49
, pp. 647-652
-
-
Brawer, J.R.1
Beaudet, A.2
Desjardins, G.C.3
Schipper, H.M.4
-
8
-
-
0141618477
-
The long (LINEs) and the short (SINEs) of it: Altered methylation as a precursor to toxicity
-
Carnell, A. N., and Goodman, J. I. (2003). The long (LINEs) and the short (SINEs) of it: Altered methylation as a precursor to toxicity. Toxicol. Sci. 75, 229-235.
-
(2003)
Toxicol. Sci.
, vol.75
, pp. 229-235
-
-
Carnell, A.N.1
Goodman, J.I.2
-
9
-
-
0033655310
-
Estrogens as endogenous genotoxic agents-DNA adducts and mutations
-
Cavalieri, E., Fenkel, K., Liehr, J. G., Rogan, E., and Roy, D. (2000). Estrogens as endogenous genotoxic agents-DNA adducts and mutations. J. Natl. Cancer Inst. Monogr. 27, 75-93.
-
(2000)
J. Natl. Cancer Inst. Monogr.
, vol.27
, pp. 75-93
-
-
Cavalieri, E.1
Fenkel, K.2
Liehr, J.G.3
Rogan, E.4
Roy, D.5
-
10
-
-
0028826889
-
Cytochromes CYP1A1 and CYP1B1 in the rat mammary gland: Cell-specific expression and regulation by polycyclic aromatic hydrocarbons and hormones
-
Christou, M., Savas, U., Schroeder, S., Shen, X., Thompson, T., Gould, M. N., and Jefcoate, C. R. (1995). Cytochromes CYP1A1 and CYP1B1 in the rat mammary gland: Cell-specific expression and regulation by polycyclic aromatic hydrocarbons and hormones. Mol. Cell. Endocrinol. 115, 41-50.
-
(1995)
Mol. Cell. Endocrinol.
, vol.115
, pp. 41-50
-
-
Christou, M.1
Savas, U.2
Schroeder, S.3
Shen, X.4
Thompson, T.5
Gould, M.N.6
Jefcoate, C.R.7
-
11
-
-
2442705705
-
DNA methylation and male infertility
-
Cisneros, F. J. (2004). DNA methylation and male infertility. Frontiers Biosci. 9, 1189-1200.
-
(2004)
Frontiers Biosci.
, vol.9
, pp. 1189-1200
-
-
Cisneros, F.J.1
-
12
-
-
2342625969
-
Neurochemical basis for an epigenetic vision of synaptic organization
-
Costa, E., Grayson, D. R., Veldic, M., and Guidotti, A. (2004). Neurochemical basis for an epigenetic vision of synaptic organization. Int. Rev. Neurobiol. 59, 73-91.
-
(2004)
Int. Rev. Neurobiol.
, vol.59
, pp. 73-91
-
-
Costa, E.1
Grayson, D.R.2
Veldic, M.3
Guidotti, A.4
-
13
-
-
27244435366
-
Effects of postnatal exposure to a mixture of PCBs, p,p′-DDT and p,p′-DDE in prepubertal and adult female Sprague-Dawley rats
-
Desaulniers, D., Cooke, G. M., Leingartner, K., Soumano, K., Cole, J., Yang, J., Wade, M. G., and Yagminas, A. (2005). Effects of postnatal exposure to a mixture of PCBs, p,p′-DDT and p,p′-DDE in prepubertal and adult female Sprague-Dawley rats. Int. J. Toxicol. 24, 1-17.
-
(2005)
Int. J. Toxicol.
, vol.24
, pp. 1-17
-
-
Desaulniers, D.1
Cooke, G.M.2
Leingartner, K.3
Soumano, K.4
Cole, J.5
Yang, J.6
Wade, M.G.7
Yagminas, A.8
-
14
-
-
4444326522
-
Effects of postnatal exposure to a mixture of aryl hydrocarbon-receptor agonists on the development of methylnitrosourea-induced mammary tumours in female Sprague-Dawley rat
-
Desaulniers, D., Leingartner, K., Musicki, B., Cole, J., Li, M., Charbonneau, M., and Tsang, B. K. (2004). Effects of postnatal exposure to a mixture of aryl hydrocarbon-receptor agonists on the development of methylnitrosourea-induced mammary tumours in female Sprague-Dawley rat. J. Toxicol. Environ. Health Part A 67, 1-19.
-
(2004)
J. Toxicol. Environ. Health Part A
, vol.67
, pp. 1-19
-
-
Desaulniers, D.1
Leingartner, K.2
Musicki, B.3
Cole, J.4
Li, M.5
Charbonneau, M.6
Tsang, B.K.7
-
15
-
-
0141507039
-
Effects of postnatal exposure to mixtures of non-ortho-PCBs, PCDDs and PCDFs in prepubertal female rats
-
Desaulniers, D., Leingartner, K., Musicki, B., Yagminas, A., Xiao, G., Cole, J., Marro, L., Charbonneau, M., and Tsang, B. K. (2003). Effects of postnatal exposure to mixtures of non-ortho-PCBs, PCDDs and PCDFs in prepubertal female rats. Toxicol. Sci. 75, 468-480.
-
(2003)
Toxicol. Sci.
, vol.75
, pp. 468-480
-
-
Desaulniers, D.1
Leingartner, K.2
Musicki, B.3
Yagminas, A.4
Xiao, G.5
Cole, J.6
Marro, L.7
Charbonneau, M.8
Tsang, B.K.9
-
16
-
-
0034865946
-
Modulatory effects of neonatal exposure to TCDD, or a mixture of PCBs, p,p′-DDT and p.p′-DDE, on methylnitrosourea-induced mammary tumor development in the rat
-
Desaulniers, D., Leingartner, K., Russo, J., Perkins, G., Chittim, B. G., Archer, M. C., Wade, M., and Yang, J. (2001). Modulatory effects of neonatal exposure to TCDD, or a mixture of PCBs, p,p′-DDT and p.p′-DDE, on methylnitrosourea-induced mammary tumor development in the rat. Environ. Health Perspect. 109, 739-747.
-
(2001)
Environ. Health Perspect.
, vol.109
, pp. 739-747
-
-
Desaulniers, D.1
Leingartner, K.2
Russo, J.3
Perkins, G.4
Chittim, B.G.5
Archer, M.C.6
Wade, M.7
Yang, J.8
-
17
-
-
0027074344
-
Breast milk contamination by PCDDs, PCDFs and PCBs in arctic Quebec: A preliminary assessment
-
Dewailly, E., Nantel, A., Bruneau, S., Laliberte, C., Ferron, L., and Gingras, S. (1992). Breast milk contamination by PCDDs, PCDFs and PCBs in arctic Quebec: A preliminary assessment. Chemosphere 25, 1245-1249.
-
(1992)
Chemosphere
, vol.25
, pp. 1245-1249
-
-
Dewailly, E.1
Nantel, A.2
Bruneau, S.3
Laliberte, C.4
Ferron, L.5
Gingras, S.6
-
18
-
-
1642539022
-
Cardiovascular pharmacology of estradiol metabolites
-
Dubey, R. K., Tofovic, S. P., and Jackson, E. K. (2004). Cardiovascular pharmacology of estradiol metabolites. J. Pharmacol. Exp. Ther. 308, 403-409.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.308
, pp. 403-409
-
-
Dubey, R.K.1
Tofovic, S.P.2
Jackson, E.K.3
-
19
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
Eden, A., Gaudet, F., Waghmare, A., and Jaenisch, R. (2003). Chromosomal instability and tumors promoted by DNA hypomethylation. Science 300, 455.
-
(2003)
Science
, vol.300
, pp. 455
-
-
Eden, A.1
Gaudet, F.2
Waghmare, A.3
Jaenisch, R.4
-
20
-
-
2642531973
-
Epigenetics in human disease and prospects for epigenetic therapy
-
Egger, G., Liang, G., Aparicio, A., and Jones, P. A. (2004). Epigenetics in human disease and prospects for epigenetic therapy. Nature 429, 457-463.
-
(2004)
Nature
, vol.429
, pp. 457-463
-
-
Egger, G.1
Liang, G.2
Aparicio, A.3
Jones, P.A.4
-
21
-
-
0034045705
-
Health risks to infants from exposure to PCBs, PCDDs and PCDFs
-
Feeley, M., and Brouwer, A. (2000). Health risks to infants from exposure to PCBs, PCDDs and PCDFs. Food Addit. Contam. 17, 325-333.
-
(2000)
Food Addit. Contam.
, vol.17
, pp. 325-333
-
-
Feeley, M.1
Brouwer, A.2
-
22
-
-
0023820106
-
Organochlorine residues in adipose tissues, blood and milk from Ontario residents, 1976-1985
-
Frank, R., Rasper, J., Smout, M. S., and Braun, H. E. (1988). Organochlorine residues in adipose tissues, blood and milk from Ontario residents, 1976-1985. Can. J. Public Health 79, 150-158.
-
(1988)
Can. J. Public Health
, vol.79
, pp. 150-158
-
-
Frank, R.1
Rasper, J.2
Smout, M.S.3
Braun, H.E.4
-
23
-
-
0034650365
-
Catechol metabolites of polychlorinated biphenyls inhibit the catechol-O-methyltransferase-mediated metabolism of catechol estrogens
-
Garner, C. E., Burka, L. T., Etheridge, A. E., and Matthews, H. B. (2000). Catechol metabolites of polychlorinated biphenyls inhibit the catechol-O-methyltransferase-mediated metabolism of catechol estrogens. Toxicol. Appl. Pharmacol. 162, 115-123.
-
(2000)
Toxicol. Appl. Pharmacol.
, vol.162
, pp. 115-123
-
-
Garner, C.E.1
Burka, L.T.2
Etheridge, A.E.3
Matthews, H.B.4
-
24
-
-
0242584449
-
Induction of tumors in mice by genomic hypomethylation
-
Gaudet, F., Hodgson, J. G., Eden, A., Jackson-Grusby, L., Dausman, J., Gray, J. W., Leonhardt, H., and Jaenisch, R. (2003). Induction of tumors in mice by genomic hypomethylation. Science 300, 489-492.
-
(2003)
Science
, vol.300
, pp. 489-492
-
-
Gaudet, F.1
Hodgson, J.G.2
Eden, A.3
Jackson-Grusby, L.4
Dausman, J.5
Gray, J.W.6
Leonhardt, H.7
Jaenisch, R.8
-
25
-
-
0038526391
-
Sources and significance of plasma levels of catechols and their metabolites in humans
-
Goldstein, D. S., Eisenhofer, G., and Kopin, I. J. (2003). Sources and significance of plasma levels of catechols and their metabolites in humans. J. Pharmacol. Exp. Ther. 305, 800-811.
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, pp. 800-811
-
-
Goldstein, D.S.1
Eisenhofer, G.2
Kopin, I.J.3
-
26
-
-
0037372835
-
CYP1A1 and CYP1B1 in blood-brain interfaces: CYP1A1-dependent bioactivation of 7,12-dimethylbenz(a)anthracene in endothelial cells
-
Granberg, L., Ostergren, A., Brandt, I., and Brittebo, E. B. (2003). CYP1A1 and CYP1B1 in blood-brain interfaces: CYP1A1-dependent bioactivation of 7,12-dimethylbenz(a)anthracene in endothelial cells. Drug Metab. Dispos. 31, 259-265.
-
(2003)
Drug Metab. Dispos.
, vol.31
, pp. 259-265
-
-
Granberg, L.1
Ostergren, A.2
Brandt, I.3
Brittebo, E.B.4
-
27
-
-
0029796550
-
17β-estradiol hydroxylation catalyzed by human cytochrome P450 1B1
-
Hayes, C. L., Spink, D. C., Spink, B. C., Cao, J. Q., Walker, N. J., and Sutter, T. R. (1996). 17β-estradiol hydroxylation catalyzed by human cytochrome P450 1B1. Proc. Natl. Acad. Sci. U.S.A. 93, 9776-9781.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 9776-9781
-
-
Hayes, C.L.1
Spink, D.C.2
Spink, B.C.3
Cao, J.Q.4
Walker, N.J.5
Sutter, T.R.6
-
28
-
-
0020213985
-
The catechol estrogen, 2-hydroxyestradiol-17 alpha, is formed from estradiol-17 alpha by hypothalamic tissue in vitro and inhibits tyrosine hydroxylase
-
Hersey, R. M., Lloyd, T., Maclusky, N. J., and Weisz, J. (1982). The catechol estrogen, 2-hydroxyestradiol-17 alpha, is formed from estradiol-17 alpha by hypothalamic tissue in vitro and inhibits tyrosine hydroxylase. Endocrinology 111, 1734-1736.
-
(1982)
Endocrinology
, vol.111
, pp. 1734-1736
-
-
Hersey, R.M.1
Lloyd, T.2
Maclusky, N.J.3
Weisz, J.4
-
29
-
-
0034033836
-
Ontogenetic expression and sex differences of aromatase and estrogen receptor-alpha/beta mRNA in the mouse hippocampus
-
Ivanova, T., and Beyer, C. (2000). Ontogenetic expression and sex differences of aromatase and estrogen receptor-alpha/beta mRNA in the mouse hippocampus. Cell Tissue Res. 300, 231-237.
-
(2000)
Cell Tissue Res.
, vol.300
, pp. 231-237
-
-
Ivanova, T.1
Beyer, C.2
-
30
-
-
0037372217
-
Estrogen regulates tyrosine hydroxylase expression in the neonate mouse midbrain
-
Ivanova, T., and Beyer, C. (2003). Estrogen regulates tyrosine hydroxylase expression in the neonate mouse midbrain. J. Neurobiol. 54, 638-647.
-
(2003)
J. Neurobiol.
, vol.54
, pp. 638-647
-
-
Ivanova, T.1
Beyer, C.2
-
31
-
-
0033657888
-
Tissue-specific synthesis and oxidative metabolism of estrogens
-
Jefcoate, C. R., Liehr, J. G., Santen, R. J., Sutter, T. R., Yager, J. D., Yue, W., Santner, S. J., Tekmal, R., Demers, L., Pauley, R. et al. (2000). Tissue-specific synthesis and oxidative metabolism of estrogens. J. Natl. Cancer Inst. Monogr. 27, 95-112.
-
(2000)
J. Natl. Cancer Inst. Monogr.
, vol.27
, pp. 95-112
-
-
Jefcoate, C.R.1
Liehr, J.G.2
Santen, R.J.3
Sutter, T.R.4
Yager, J.D.5
Yue, W.6
Santner, S.J.7
Tekmal, R.8
Demers, L.9
Pauley, R.10
-
32
-
-
0038620494
-
Cellular strategies of estrogen-mediated neuroprotection during brain development
-
Kajta, M., and Beyer, C. (2003). Cellular strategies of estrogen-mediated neuroprotection during brain development. Endocrine 21, 3-9.
-
(2003)
Endocrine
, vol.21
, pp. 3-9
-
-
Kajta, M.1
Beyer, C.2
-
33
-
-
3042584653
-
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting
-
Kaneda, M., Okano, M., Hata, K., Sado, T., Tsujimoto, N., Li, E., and Sasaki, H. (2004). Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature 429, 900-903.
-
(2004)
Nature
, vol.429
, pp. 900-903
-
-
Kaneda, M.1
Okano, M.2
Hata, K.3
Sado, T.4
Tsujimoto, N.5
Li, E.6
Sasaki, H.7
-
34
-
-
0034811778
-
The OECD program to validate the rat uterotrophic bioassay to screen compounds for in vivo estrogenic responses: Phase 1
-
Kanno, J., Onyon, L., Haseman, J., Fenner-Crisp, P., Ashby, J., and Owens, W. (2001). The OECD program to validate the rat uterotrophic bioassay to screen compounds for in vivo estrogenic responses: Phase 1. Environ. Health Perspect. 109, 785-794.
-
(2001)
Environ. Health Perspect.
, vol.109
, pp. 785-794
-
-
Kanno, J.1
Onyon, L.2
Haseman, J.3
Fenner-Crisp, P.4
Ashby, J.5
Owens, W.6
-
35
-
-
0141451919
-
The OECD program to validate the rat uterotrophic bioassay. Phase 2: Coded single-dose studies
-
Kanno, J., Onyon, L., Peddada, S., Ashby, J., Jacob, E., and Owens, W. (2003a). The OECD program to validate the rat uterotrophic bioassay. Phase 2: Coded single-dose studies. Environ. Health Perspect. 111, 1550-1558.
-
(2003)
Environ. Health Perspect.
, vol.111
, pp. 1550-1558
-
-
Kanno, J.1
Onyon, L.2
Peddada, S.3
Ashby, J.4
Jacob, E.5
Owens, W.6
-
36
-
-
0041698394
-
The OECD program to validate the rat uterotrophic bioassay. Phase 2: Dose-response studies
-
Kanno, J., Onyon, L., Peddada, S., Ashby, J., Jacob, E., and Owens, W. (2003b). The OECD program to validate the rat uterotrophic bioassay. Phase 2: Dose-response studies. Environ. Health Perspect. 111, 1530-1549.
-
(2003)
Environ. Health Perspect.
, vol.111
, pp. 1530-1549
-
-
Kanno, J.1
Onyon, L.2
Peddada, S.3
Ashby, J.4
Jacob, E.5
Owens, W.6
-
37
-
-
0142243222
-
Control elements of Dnmt1 gene are regulated in a cell-cycle dependent manner
-
Kishikawa, S., Murata, T., Ugai, H., Yamazaki, T., and Yokoyama, K. K. (2003). Control elements of Dnmt1 gene are regulated in a cell-cycle dependent manner. Nucleic Acids Res. Suppl. 307-308.
-
(2003)
Nucleic Acids Res. Suppl.
, pp. 307-308
-
-
Kishikawa, S.1
Murata, T.2
Ugai, H.3
Yamazaki, T.4
Yokoyama, K.K.5
-
38
-
-
15744403562
-
Stage-by-stage change in DNA methylation status of DNA methyltransferase 1 (Dnmt1) locus during mouse early development
-
Ko, Y. G., Nishino, K., Hattori, N., Arai, Y., Tanaka, S., and Shiota, K. (2005). Stage-by-stage change in DNA methylation status of DNA methyltransferase 1 (Dnmt1) locus during mouse early development. J. Biol. Chem. 280, 9627-34.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 9627-9634
-
-
Ko, Y.G.1
Nishino, K.2
Hattori, N.3
Arai, Y.4
Tanaka, S.5
Shiota, K.6
-
39
-
-
1242353081
-
Metabolism and DNA binding studies of 4-hydroxyestradiol and estradiol-3,4-quinone in vitro and in female ACI rat mammary gland in vivo
-
Li, K. M., Todorovic, R., Devanesan, P., Higginbotham, S., Kofeler, H., Ramanathan, R., Gross, M. L., Rogan, E. G., and Cavalieri, E. L. (2004). Metabolism and DNA binding studies of 4-hydroxyestradiol and estradiol-3,4-quinone in vitro and in female ACI rat mammary gland in vivo. Carcinogenesis 25, 289-297.
-
(2004)
Carcinogenesis
, vol.25
, pp. 289-297
-
-
Li, K.M.1
Todorovic, R.2
Devanesan, P.3
Higginbotham, S.4
Kofeler, H.5
Ramanathan, R.6
Gross, M.L.7
Rogan, E.G.8
Cavalieri, E.L.9
-
40
-
-
0001868220
-
Consideration of enzyme and endocrine interactions in the risk assessment of PCBs
-
Li, M.-H., and Hansen, L. G. (1997). Consideration of enzyme and endocrine interactions in the risk assessment of PCBs. Rev. Toxicol. 1, 71-156.
-
(1997)
Rev. Toxicol.
, vol.1
, pp. 71-156
-
-
Li, M.-H.1
Hansen, L.G.2
-
41
-
-
2542502650
-
Interactions within the mammalian DNA methyltransferase family
-
Margot, J. B., Ehrenhofer-Murray, A. E., and Leonhardt, H. (2003). Interactions within the mammalian DNA methyltransferase family. BMC Mol. Biol. 4, 7.
-
(2003)
BMC Mol. Biol.
, vol.4
, pp. 7
-
-
Margot, J.B.1
Ehrenhofer-Murray, A.E.2
Leonhardt, H.3
-
42
-
-
15644382106
-
Comparative carcinogenicity in Sprague-Dawley rats of the polychlorinated biphenyl mixtures Aroclors 1016, 1242, 1254, and 1260
-
Mayes, B. A., McConnell, E. E., Neal, B. H., Brunner, M. J., Hamilton, S. B., Sullivan, T. M., Peters, A. C., Ryan, M. J., Toft, J. D., Singer, A. W. et al. (1998). Comparative carcinogenicity in Sprague-Dawley rats of the polychlorinated biphenyl mixtures Aroclors 1016, 1242, 1254, and 1260. Toxicol. Sci. 41, 62-76.
-
(1998)
Toxicol. Sci.
, vol.41
, pp. 62-76
-
-
Mayes, B.A.1
McConnell, E.E.2
Neal, B.H.3
Brunner, M.J.4
Hamilton, S.B.5
Sullivan, T.M.6
Peters, A.C.7
Ryan, M.J.8
Toft, J.D.9
Singer, A.W.10
-
43
-
-
4344569248
-
The role of chromatin in molecular mechanisms of toxicity
-
Moggs, J. G., and Orphanides, G. (2004). The role of chromatin in molecular mechanisms of toxicity. Toxicol. Sci. 80, 218-224.
-
(2004)
Toxicol. Sci.
, vol.80
, pp. 218-224
-
-
Moggs, J.G.1
Orphanides, G.2
-
44
-
-
0035036154
-
Regulation, function, and tissue-specific expression of cytochrome P450 CYP1B1
-
Murray, G. I., Melvin, W. T., Greenlee, W. E, and Burke, M. D. (2001). Regulation, function, and tissue-specific expression of cytochrome P450 CYP1B1. Annu. Rev. Pharmacol. Toxicol. 41, 297-316.
-
(2001)
Annu. Rev. Pharmacol. Toxicol.
, vol.41
, pp. 297-316
-
-
Murray, G.I.1
Melvin, W.T.2
Greenlee, W.E.3
Burke, M.D.4
-
45
-
-
0036194762
-
Transplacental effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the temporal modulation of Sp1 DNA binding in the developing cerebral cortex and cerebellum
-
Nayyar, T., Zawia, N. H., and Hood, D. B. (2002). Transplacental effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the temporal modulation of Sp1 DNA binding in the developing cerebral cortex and cerebellum. Exp. Toxicol. Pathol. 53, 461-468.
-
(2002)
Exp. Toxicol. Pathol.
, vol.53
, pp. 461-468
-
-
Nayyar, T.1
Zawia, N.H.2
Hood, D.B.3
-
46
-
-
0036445966
-
Evaluation of Tier I screening approaches for detecting endocrine-active compounds (EACs)
-
O'Connor, J. C., Cook, J. C., Marty, M. S., Davis, L. G., Kaplan, A. M., and Carney, E. W. (2002). Evaluation of Tier I screening approaches for detecting endocrine-active compounds (EACs). Crit. Rev. Toxicol. 32, 521-549.
-
(2002)
Crit. Rev. Toxicol.
, vol.32
, pp. 521-549
-
-
O'Connor, J.C.1
Cook, J.C.2
Marty, M.S.3
Davis, L.G.4
Kaplan, A.M.5
Carney, E.W.6
-
47
-
-
0037452665
-
Aging results in hypermethylation of ribosomal DNA in sperm and liver of male rats
-
Oakes, C. C., Smiraglia, D. J., Plass, C., Trasler, J. M., and Robaire, B. (2003). Aging results in hypermethylation of ribosomal DNA in sperm and liver of male rats. Proc. Natl. Acad. Sci. U.S.A. 100, 1775-1780.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 1775-1780
-
-
Oakes, C.C.1
Smiraglia, D.J.2
Plass, C.3
Trasler, J.M.4
Robaire, B.5
-
48
-
-
0038100188
-
Modulation of oestrogen receptor signalling by association with the activated dioxin receptor
-
Ohtake, F., Takeyama, K., Matsumoto, T., Kitagawa, H., Yamamoto, Y., Nohara, K., Tohyama, C., Krust, A., Mimura, J., Chambon, P. et al. (2003). Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature 423, 545-550.
-
(2003)
Nature
, vol.423
, pp. 545-550
-
-
Ohtake, F.1
Takeyama, K.2
Matsumoto, T.3
Kitagawa, H.4
Yamamoto, Y.5
Nohara, K.6
Tohyama, C.7
Krust, A.8
Mimura, J.9
Chambon, P.10
-
49
-
-
0038464933
-
The OECD program to validate the rat uterotrophic bioassay. Phase 2: Dietary phytoestrogen analyses
-
Owens, W., Ashby, J., Odum, J., and Onyon, L. (2003). The OECD program to validate the rat uterotrophic bioassay. Phase 2: Dietary phytoestrogen analyses. Environ. Health Perspect. 111, 1559-1567.
-
(2003)
Environ. Health Perspect.
, vol.111
, pp. 1559-1567
-
-
Owens, W.1
Ashby, J.2
Odum, J.3
Onyon, L.4
-
50
-
-
0141517411
-
The OECD program to validate the rat uterotrophic bioassay: An overview
-
Owens, W., and Koeter, H. B. (2003). The OECD program to validate the rat uterotrophic bioassay: An overview. Environ. Health Perspect. 111, 1527-1529.
-
(2003)
Environ. Health Perspect.
, vol.111
, pp. 1527-1529
-
-
Owens, W.1
Koeter, H.B.2
-
51
-
-
0031782902
-
Coordination of differential effects of primary estrogen and catecholestrogen on two distinct targets mediates embryo implantation in the mouse
-
Paria, B. C., Lim, H., Wang, X. N., Liehr, J., Das, S. K., and Dey, S. K. (1998). Coordination of differential effects of primary estrogen and catecholestrogen on two distinct targets mediates embryo implantation in the mouse. Endocrinology 139, 5235-5246.
-
(1998)
Endocrinology
, vol.139
, pp. 5235-5246
-
-
Paria, B.C.1
Lim, H.2
Wang, X.N.3
Liehr, J.4
Das, S.K.5
Dey, S.K.6
-
52
-
-
2442696623
-
Molecular and cellular determinants of estrogen receptor alpha expression
-
Pinzone, J. J., Stevenson, H., Strobl, J. S., and Berg, P. E. (2004). Molecular and cellular determinants of estrogen receptor alpha expression. Mol. Cell. Biol. 24, 4605-4612.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 4605-4612
-
-
Pinzone, J.J.1
Stevenson, H.2
Strobl, J.S.3
Berg, P.E.4
-
53
-
-
3142703591
-
Dose-dependence, sex- and tissue-specificity, and persistence of radiation-induced genomic DNA methylation changes
-
Pogribny, I., Raiche, J., Slovack, M., and Kovalchuk, O. (2004). Dose-dependence, sex- and tissue-specificity, and persistence of radiation-induced genomic DNA methylation changes. Biochem. Biophys. Res. Commun. 320, 1253-1261.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.320
, pp. 1253-1261
-
-
Pogribny, I.1
Raiche, J.2
Slovack, M.3
Kovalchuk, O.4
-
54
-
-
0032863770
-
Ontogenetic expression and splicing of estrogen receptor-alpha and beta mRNA in the rat midbrain
-
Raab, H., Karolczak, M., Reisert, I., and Beyer, C. (1999). Ontogenetic expression and splicing of estrogen receptor-alpha and beta mRNA in the rat midbrain. Neurosci. Lett. 275, 21-24.
-
(1999)
Neurosci. Lett.
, vol.275
, pp. 21-24
-
-
Raab, H.1
Karolczak, M.2
Reisert, I.3
Beyer, C.4
-
55
-
-
3042695024
-
Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a
-
Ray, S. S., and Swanson, H. I. (2004). Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a. J. Biol. Chem. 279, 27187-27193.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27187-27193
-
-
Ray, S.S.1
Swanson, H.I.2
-
56
-
-
0035839126
-
Epigenetic reprogramming in mammalian development
-
Reik, W., Dean, W., and Walter, J. (2001). Epigenetic reprogramming in mammalian development. Science 293, 1089-1093.
-
(2001)
Science
, vol.293
, pp. 1089-1093
-
-
Reik, W.1
Dean, W.2
Walter, J.3
-
57
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
Rhee, I., Bachman, K. E., Park, B. H., Jair, K. W., Yen, R. W., Schuebel, K. E., Cui, H., Feinberg, A. P., Lengauer, C., Kinzler, K. W. et al. (2002). DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 416, 552-556.
-
(2002)
Nature
, vol.416
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
Jair, K.W.4
Yen, R.W.5
Schuebel, K.E.6
Cui, H.7
Feinberg, A.P.8
Lengauer, C.9
Kinzler, K.W.10
-
58
-
-
0023153738
-
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic and uterine estrogen receptor levels in rats
-
Romkes, M., Piskorska-Pliszczynska, J., and Safe, S. (1987). Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic and uterine estrogen receptor levels in rats. Toxicol. Appl. Pharmacol. 87, 306-314.
-
(1987)
Toxicol. Appl. Pharmacol.
, vol.87
, pp. 306-314
-
-
Romkes, M.1
Piskorska-Pliszczynska, J.2
Safe, S.3
-
59
-
-
0024997614
-
Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs)
-
Safe, S. (1990). Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). C.R.C. Crit. Rev. Toxicol. 21, 51-88.
-
(1990)
C.R.C. Crit. Rev. Toxicol.
, vol.21
, pp. 51-88
-
-
Safe, S.1
-
60
-
-
0025719532
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds as antioestrogens: Characterization and mechanism of action
-
Safe, S., Astroff, B., Harris, M., Zacharewski, T., Dickerson, R., Romkes, M., and Biegel, L. (1991). 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds as antioestrogens: Characterization and mechanism of action. Pharmacol. Toxicol. 69, 400-409.
-
(1991)
Pharmacol. Toxicol.
, vol.69
, pp. 400-409
-
-
Safe, S.1
Astroff, B.2
Harris, M.3
Zacharewski, T.4
Dickerson, R.5
Romkes, M.6
Biegel, L.7
-
61
-
-
0003160370
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related environmental antiestrogens: Characterization and mechanism of action
-
(Naz, R. K., Ed.), CRC Press, Boca Raton, FL
-
Safe, S. H. (1999). 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related environmental antiestrogens: Characterization and mechanism of action. In Endocrine Disruptors: Effects on Male and Female Reproductive Systems (Naz, R. K., Ed.), pp. 187-221. CRC Press, Boca Raton, FL.
-
(1999)
Endocrine Disruptors: Effects on Male and Female Reproductive Systems
, pp. 187-221
-
-
Safe, S.H.1
-
62
-
-
0034019758
-
Differential and non-uniform tissue and brain distribution of two distinct 14C-hexachlorobiphenyls in wearding rats
-
Saghir, S. A., Hansen, L. G., Holmes, K. R., and Kodavanti, P. R. (2000). Differential and non-uniform tissue and brain distribution of two distinct 14C-hexachlorobiphenyls in wearding rats. Toxicol. Sci. 54, 60-70.
-
(2000)
Toxicol. Sci.
, vol.54
, pp. 60-70
-
-
Saghir, S.A.1
Hansen, L.G.2
Holmes, K.R.3
Kodavanti, P.R.4
-
63
-
-
0032965089
-
Short term distribution, metabolism, and excretion of 2,2′,5-tri, 2,2′,4,4′-tetra-, and 3,3′,4,4′-tetrachlorobiphenyls in prepubertal rats
-
Saghir, S. A., Koritz, G. D., and Hansen, L. G. (1999). Short term distribution, metabolism, and excretion of 2,2′,5-tri, 2,2′,4,4′-tetra-, and 3,3′,4,4′-tetrachlorobiphenyls in prepubertal rats. Arch. Environ. Contam. Toxicol. 36, 213-220.
-
(1999)
Arch. Environ. Contam. Toxicol.
, vol.36
, pp. 213-220
-
-
Saghir, S.A.1
Koritz, G.D.2
Hansen, L.G.3
-
64
-
-
0003763117
-
-
SAS Institute Inc Version 3 SAS Institute Inc, Cary, NC
-
SAS Institute Inc (1998). IMP Statistics and Graphics Guide, Version 3, pp. 1-593. SAS Institute Inc, Cary, NC.
-
(1998)
IMP Statistics and Graphics Guide
, pp. 1-593
-
-
-
65
-
-
0037352430
-
Effects of PCB exposure on neuropsychological function in children
-
Schantz, S. L., Widholm, J. J., and Rice, D. C. (2003). Effects of PCB exposure on neuropsychological function in children. Environ. Health Perspect. 111, 357-576.
-
(2003)
Environ. Health Perspect.
, vol.111
, pp. 357-576
-
-
Schantz, S.L.1
Widholm, J.J.2
Rice, D.C.3
-
66
-
-
2542588520
-
Inhibition of human breast cancer cell proliferation with estradiol metabolites is as effective as with tamoxifen
-
Seeger, H., Huober, J., Wallwiener, D., and Mueek, A. O. (2004). Inhibition of human breast cancer cell proliferation with estradiol metabolites is as effective as with tamoxifen. Horm. Metab. Res. 36, 277-280.
-
(2004)
Horm. Metab. Res.
, vol.36
, pp. 277-280
-
-
Seeger, H.1
Huober, J.2
Wallwiener, D.3
Mueek, A.O.4
-
67
-
-
0036082912
-
Chemical contaminants in breast milk: Time trends and regional variability
-
Solomon, G. M., and Weiss, P. M. (2002). Chemical contaminants in breast milk: Time trends and regional variability. Environ. Health Perspect. 110, A339-A347.
-
(2002)
Environ. Health Perspect.
, vol.110
-
-
Solomon, G.M.1
Weiss, P.M.2
-
68
-
-
0348149138
-
Estrogen regulates Ah responsiveness in MCF-7 breast cancer cells
-
Spink, D. C., Katz, B. H., Hussain, M. M., Pentecost, B. T., Cao, Z., and Spink, B. C. (2003). Estrogen regulates Ah responsiveness in MCF-7 breast cancer cells. Carcinogenesis 24, 1941-1950.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1941-1950
-
-
Spink, D.C.1
Katz, B.H.2
Hussain, M.M.3
Pentecost, B.T.4
Cao, Z.5
Spink, B.C.6
-
69
-
-
0026793175
-
Nucleotide sequence of estrogen receptor cDNA from Sprague-Dawley rat
-
Spreafico, E., Bettini, E., Pollio, G., and Maggi, A. (1992). Nucleotide sequence of estrogen receptor cDNA from Sprague-Dawley rat. Eur. J. Pharmacol. 227, 353-356.
-
(1992)
Eur. J. Pharmacol.
, vol.227
, pp. 353-356
-
-
Spreafico, E.1
Bettini, E.2
Pollio, G.3
Maggi, A.4
-
70
-
-
0027483404
-
Structure of the rat catechol-O-methyltransferase gene: Separate promoters are used to produce mRNAs for soluble and membrane-bound forms of the enzyme
-
Tenhunen, J., Salminen, M., Jalanko, A., Ukkonen, S., and Ulmanen, I. (1993). Structure of the rat catechol-O-methyltransferase gene: Separate promoters are used to produce mRNAs for soluble and membrane-bound forms of the enzyme. DNA Cell Biol. 12, 253-263.
-
(1993)
DNA Cell Biol.
, vol.12
, pp. 253-263
-
-
Tenhunen, J.1
Salminen, M.2
Jalanko, A.3
Ukkonen, S.4
Ulmanen, I.5
-
71
-
-
0035192862
-
2-Hydroxyestradiol attenuates the development of obesity, the metabolic syndrome, and vascular and renal dysfunction in obese ZSF1 rats
-
Tofovic, S. P., Dubey, R. K., and Jackson, E. K. (2001). 2-Hydroxyestradiol attenuates the development of obesity, the metabolic syndrome, and vascular and renal dysfunction in obese ZSF1 rats. J. Pharmacol. Exp. Ther. 299, 973-977.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.299
, pp. 973-977
-
-
Tofovic, S.P.1
Dubey, R.K.2
Jackson, E.K.3
-
72
-
-
0036509526
-
Toxicological consequences of differential regulation of cytochrome P450 isoforms in rat brain regions by phenobarbital
-
Upadhya, S. C., Chinta, S. J., Pai, H. V., Boyd, M. R., and Ravindranath, V. (2002). Toxicological consequences of differential regulation of cytochrome P450 isoforms in rat brain regions by phenobarbital. Arch. Biochem. Biophys. 399, 56-65.
-
(2002)
Arch. Biochem. Biophys.
, vol.399
, pp. 56-65
-
-
Upadhya, S.C.1
Chinta, S.J.2
Pai, H.V.3
Boyd, M.R.4
Ravindranath, V.5
-
73
-
-
0032449610
-
Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife
-
Van den Berg, M., Birnbaum, L., Bosveld, A. T. C., Brunstrom, B., Cook, P., Feeley, M., Giesy, J. P., Hanberg, A., Hasegawa, R., Kennedy, S. W. et al. (1998). Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ. Health Perspect. 106, 775-792.
-
(1998)
Environ. Health Perspect.
, vol.106
, pp. 775-792
-
-
Van den Berg, M.1
Birnbaum, L.2
Bosveld, A.T.C.3
Brunstrom, B.4
Cook, P.5
Feeley, M.6
Giesy, J.P.7
Hanberg, A.8
Hasegawa, R.9
Kennedy, S.W.10
-
74
-
-
0036078283
-
Sexually dimorphic nonreproductive behaviors as indicators of endocrine disruption
-
Weiss, B. (2002). Sexually dimorphic nonreproductive behaviors as indicators of endocrine disruption. Environ. Health Perspect. 110 (Suppl 3), 387-391.
-
(2002)
Environ. Health Perspect.
, vol.110
, Issue.SUPPL. 3
, pp. 387-391
-
-
Weiss, B.1
-
75
-
-
0029117773
-
Weanling female Sprague-Dawley rats are not sensitive to the antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
-
White, T. E. K., Rucci, G., Liu, Z., and Gasiewicz, T. A. (1995). Weanling female Sprague-Dawley rats are not sensitive to the antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol. Appl. Pharmacol. 133, 313-320.
-
(1995)
Toxicol. Appl. Pharmacol.
, vol.133
, pp. 313-320
-
-
White, T.E.K.1
Rucci, G.2
Liu, Z.3
Gasiewicz, T.A.4
-
76
-
-
0033569641
-
Epigenetics: Regulation through repression
-
Wolffe, A. P., and Matzke, M. A. (1999). Epigenetics: Regulation through repression. Science 286, 481-486.
-
(1999)
Science
, vol.286
, pp. 481-486
-
-
Wolffe, A.P.1
Matzke, M.A.2
-
77
-
-
0037373474
-
The aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomes
-
Wormke, M., Stoner, M., Saville, B., Walker, K., Abdelrahim, M., Burghardt, R., and Safe, S. (2003). The aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomes. Mol. Cell. Biol. 23, 1843-1855.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 1843-1855
-
-
Wormke, M.1
Stoner, M.2
Saville, B.3
Walker, K.4
Abdelrahim, M.5
Burghardt, R.6
Safe, S.7
-
78
-
-
2642540035
-
Exposure of mouse preimplantation embryos to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters the methylation status of imprinted genes H19 and Igf2
-
Wu, Q., Ohsako, S., Ishimura, R., Suzuki, J. S., and Tohyama, C. (2004). Exposure of mouse preimplantation embryos to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters the methylation status of imprinted genes H19 and Igf2. Biol. Reprod. 70, 1790-1797.
-
(2004)
Biol. Reprod.
, vol.70
, pp. 1790-1797
-
-
Wu, Q.1
Ohsako, S.2
Ishimura, R.3
Suzuki, J.S.4
Tohyama, C.5
-
79
-
-
0034945606
-
Induction of hepatic 8-oxo-deoxyguanosine adducts by 2,3,7,8-tetrachlorodibenzo-p-dioxin in Sprague-Dawley rats is female-specific and estrogen-dependent
-
Wyde, M. E., Wong, V. A., Kim, A. H., Lucier, G. W., and Walker, N. J. (2001). Induction of hepatic 8-oxo-deoxyguanosine adducts by 2,3,7,8-tetrachlorodibenzo-p-dioxin in Sprague-Dawley rats is female-specific and estrogen-dependent. Chem. Res. Toxicol. 14, 849-855.
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 849-855
-
-
Wyde, M.E.1
Wong, V.A.2
Kim, A.H.3
Lucier, G.W.4
Walker, N.J.5
-
80
-
-
4344635044
-
Identification of aberrantly methylated genes in association with adult T-cell leukemia
-
Yasunaga, J., Taniguchi, Y., Nosaka, K., Yoshida, M., Satou, Y., Sakai, T., Mitsuya, H., and Matsuoka, M. (2004). Identification of aberrantly methylated genes in association with adult T-cell leukemia. Cancer Res. 64, 6002-6009.
-
(2004)
Cancer Res.
, vol.64
, pp. 6002-6009
-
-
Yasunaga, J.1
Taniguchi, Y.2
Nosaka, K.3
Yoshida, M.4
Satou, Y.5
Sakai, T.6
Mitsuya, H.7
Matsuoka, M.8
-
81
-
-
2442689094
-
2-Hydroxyestradiol is a prodrug of 2-methoxyestradiol
-
Zacharia, L. C., Piche, C. A., Fielding, R. M., Holland, K. M., Allison, S. D., Dubey, R. K., and Jackson, E. K. (2004). 2-Hydroxyestradiol is a prodrug of 2-methoxyestradiol. J. Pharmacol. Exp. Ther 309, 1093-1097.
-
(2004)
J. Pharmacol. Exp. Ther
, vol.309
, pp. 1093-1097
-
-
Zacharia, L.C.1
Piche, C.A.2
Fielding, R.M.3
Holland, K.M.4
Allison, S.D.5
Dubey, R.K.6
Jackson, E.K.7
-
82
-
-
0035987204
-
Catechol-O-Methyltransferase (COMT)-mediated methylation metabolism of endogenous bioactive catechols and modulation by endobiotics and xenobiotics: Importance in pathophysiology and pathogenesis
-
Zhu, B. T. (2002). Catechol-O-Methyltransferase (COMT)-mediated methylation metabolism of endogenous bioactive catechols and modulation by endobiotics and xenobiotics: Importance in pathophysiology and pathogenesis. Curr. Drug Metab. 3, 321-349.
-
(2002)
Curr. Drug Metab.
, vol.3
, pp. 321-349
-
-
Zhu, B.T.1
|