Induction of hepatic 8-oxo-deoxyguanosine adducts by 2,3,7,8-tetrachlorodibenzo-p-dioxin in Sprague-Dawley rats is female-specific and estrogen-dependent

Chemical Research in Toxicology

Volumn 14, Issue 7, 2001, Pages 849-855

  Wyde, M E ^a,b   Wong, V A ^c   Kim, A H ^a,b   Lucier, G W ^b   Walker, N J ^b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c CIIT CENTERS FOR HEALTH RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 8 HYDROXYDEOXYGUANOSINE; ESTRADIOL; ESTROGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME INDUCTION; ESTROGEN METABOLISM; FEMALE; HORMONAL REGULATION; LIVER CARCINOGENESIS; LONG TERM EXPOSURE; MALE; NONHUMAN; OVARIECTOMY; SEX DIFFERENCE;

ANIMALS; CARCINOGENS; COCARCINOGENESIS; DEOXYGUANOSINE; DIETHYLNITROSAMINE; DNA; DNA ADDUCTS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; FEMALE; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS; TETRACHLORODIBENZODIOXIN;

EID: 0034945606     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx000266j     Document Type: Article

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