-
1
-
-
0028315992
-
Mechanisms of progressive renal disease in glomerulonephritis
-
COUSER WG, JOHNSON RJ: Mechanisms of progressive renal disease in glomerulonephritis. Am J Kidney Dis 23:193-198, 1994
-
(1994)
Am J Kidney Dis
, vol.23
, pp. 193-198
-
-
Couser, W.G.1
Johnson, R.J.2
-
3
-
-
0033379998
-
Experimental mesangial proliferative glomerulonephritis (the anti-Thy-1.1 model)
-
JEFFERSON JA, JOHNSON RJ: Experimental mesangial proliferative glomerulonephritis (the anti-Thy-1.1 model). J Nephrol 12:297-307, 1999
-
(1999)
J Nephrol
, vol.12
, pp. 297-307
-
-
Jefferson, J.A.1
Johnson, R.J.2
-
4
-
-
0026091034
-
Increased synthesis of extracellular matrix in mesangial proliferative nephritis
-
FLOEGE J, JOHNSON RJ, GORDON K, et al: Increased synthesis of extracellular matrix in mesangial proliferative nephritis. Kidney Int 40:477-488, 1991
-
(1991)
Kidney Int
, vol.40
, pp. 477-488
-
-
Floege, J.1
Johnson, R.J.2
Gordon, K.3
-
5
-
-
0026562550
-
Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor
-
JOHNSON RJ, RAINES EW, FLOEGE J, et al: Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor. J Exp Med 175:1413-1416, 1992
-
(1992)
J Exp Med
, vol.175
, pp. 1413-1416
-
-
Johnson, R.J.1
Raines, E.W.2
Floege, J.3
-
6
-
-
0027136163
-
Infusion of platelet-derived growth factor or basic fibroblast growth factor induces selective glomerular mesangial cell proliferation and matrix accumulation in rats
-
FLOEGE J, ENG E, YOUNG BA, et al: Infusion of platelet-derived growth factor or basic fibroblast growth factor induces selective glomerular mesangial cell proliferation and matrix accumulation in rats. J Clin Invest 92:2952-2962, 1993
-
(1993)
J Clin Invest
, vol.92
, pp. 2952-2962
-
-
Floege, J.1
Eng, E.2
Young, B.A.3
-
7
-
-
0031446329
-
Cytokines, growth factors and renal injury: Where do we go now?
-
JOHNSON RJ: Cytokines, growth factors and renal injury: Where do we go now? Kidney Int 63(Suppl):S2-6, 1997
-
(1997)
Kidney Int
, vol.63
, Issue.SUPPL.
-
-
Johnson, R.J.1
-
8
-
-
0031127304
-
Cell cycle: Routine role for Ras
-
DOWNWARD J: Cell cycle: Routine role for Ras. Curr Biol 7:R258-260, 1997
-
(1997)
Curr Biol
, vol.7
-
-
Downward, J.1
-
9
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
DOWNWARD J: Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 3:11-22, 2003
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
11
-
-
0032430523
-
Signal transduction through cytokine receptors
-
HIBI M, HIRANO T: Signal transduction through cytokine receptors. Int Rev Immunol 17:75-102, 1998
-
(1998)
Int Rev Immunol
, vol.17
, pp. 75-102
-
-
Hibi, M.1
Hirano, T.2
-
12
-
-
17344362824
-
Cell growth control by G protein-coupled receptors: From signal transduction to signal integration
-
GUTKIND JS: Cell growth control by G protein-coupled receptors: From signal transduction to signal integration. Oncogene 17:1331-1342, 1998
-
(1998)
Oncogene
, vol.17
, pp. 1331-1342
-
-
Gutkind, J.S.1
-
13
-
-
0034630098
-
Recent advances in the study of prenylated proteins
-
SINENSKY M: Recent advances in the study of prenylated proteins. Biochim Biophys Acta 1484:93-106, 2000
-
(2000)
Biochim Biophys Acta
, vol.1484
, pp. 93-106
-
-
Sinensky, M.1
-
14
-
-
0037470819
-
Protein prenylation: A pivotal posttranslational process
-
ROSKOSKI R, JR.: Protein prenylation: A pivotal posttranslational process. Biochem Biophys Res Commun 303:1-7, 2003
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 1-7
-
-
Roskoski Jr., R.1
-
15
-
-
0033538559
-
Endomembrane trafficking of ras: The CAAX motif targets proteins to the ER and Golgi
-
CHOY E, CHIU VK, SILLETTI J, et al: Endomembrane trafficking of ras: The CAAX motif targets proteins to the ER and Golgi [see comments]. Cell 98:69-80, 1999
-
(1999)
Cell
, vol.98
, pp. 69-80
-
-
Choy, E.1
Chiu, V.K.2
Silletti, J.3
-
16
-
-
0025013547
-
A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane
-
HANCOCK JF, PATERSON H, MARSHALL CJ: A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane. Cell 63:133-139, 1990
-
(1990)
Cell
, vol.63
, pp. 133-139
-
-
Hancock, J.F.1
Paterson, H.2
Marshall, C.J.3
-
17
-
-
0028959539
-
Farnesyl derivatives of rigid carboxylic acids - Inhibitors of ras-dependent cell growth
-
MARCIANO D, BEN-BARUCH G, MAROM M, et al: Farnesyl derivatives of rigid carboxylic acids - Inhibitors of ras-dependent cell growth. J Med Chem 38:1267-1272, 1995
-
(1995)
J Med Chem
, vol.38
, pp. 1267-1272
-
-
Marciano, D.1
Ben-Baruch, G.2
Marom, M.3
-
18
-
-
0032477606
-
Dislodgment and accelerated degradation of Ras
-
HAKLAI R, WEISZ MG, ELAD G, et al: Dislodgment and accelerated degradation of Ras. Biochemistry 37:1306-1314, 1998
-
(1998)
Biochemistry
, vol.37
, pp. 1306-1314
-
-
Haklai, R.1
Weisz, M.G.2
Elad, G.3
-
19
-
-
0028981375
-
Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid
-
MAROM M, HAKLAI R, BEN-BARUCH G, et al: Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid. J Biol Chem 270:22263-22270, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 22263-22270
-
-
Marom, M.1
Haklai, R.2
Ben-Baruch, G.3
-
20
-
-
0032717429
-
Targeting of K-Ras 4B by S-trans,trans-farnesyl thiosalicylic acid
-
ELAD G, PAZ A, HAKLAI R, et al: Targeting of K-Ras 4B by S-trans,trans-farnesyl thiosalicylic acid. Biochim Biophys Acta 1452:228-242, 1999
-
(1999)
Biochim Biophys Acta
, vol.1452
, pp. 228-242
-
-
Elad, G.1
Paz, A.2
Haklai, R.3
-
21
-
-
0033559885
-
Growth inhibition of ras-dependent tumors in nude mice by a potent ras-dislodging antagonist
-
EGOZI Y, WEISZ B, GANA-WEISZ M, BEN-BARUCH G, KLOOG Y: Growth inhibition of ras-dependent tumors in nude mice by a potent ras-dislodging antagonist. Int J Cancer 80:911-918, 1999
-
(1999)
Int J Cancer
, vol.80
, pp. 911-918
-
-
Egozi, Y.1
Weisz, B.2
Gana-Weisz, M.3
Ben-Baruch, G.4
Kloog, Y.5
-
22
-
-
0032731750
-
The Ras antagonist, farnesylthiosalicylic acid (FTS), inhibits experimentally induced liver cirrhosis in rats
-
REIF S, WEIS B, AEED H, et al: The Ras antagonist, farnesylthiosalicylic acid (FTS), inhibits experimentally induced liver cirrhosis in rats. J Hepatol 31:1053-1061, 1999
-
(1999)
J Hepatol
, vol.31
, pp. 1053-1061
-
-
Reif, S.1
Weis, B.2
Aeed, H.3
-
23
-
-
0035652626
-
Treatment of MRL/lpr mice, a genetic autoimmune model, with the Ras inhibitor, farnesylthiosalicylate (FTS)
-
KATZAV A, KLOOG Y, KORCZYN AD, et al: Treatment of MRL/lpr mice, a genetic autoimmune model, with the Ras inhibitor, farnesylthiosalicylate (FTS). Clin Exp Immunol 126:570-577, 2001
-
(2001)
Clin Exp Immunol
, vol.126
, pp. 570-577
-
-
Katzav, A.1
Kloog, Y.2
Korczyn, A.D.3
-
24
-
-
0037377992
-
Ras antagonist farnesylthiosalicylic acid (FTS) reduces glomerular cellular proliferation and macrophage number in rat thy-1 nephritis
-
CLARKE HC, KOCHER HM, KHWAJA A, et al: Ras antagonist farnesylthiosalicylic acid (FTS) reduces glomerular cellular proliferation and macrophage number in rat thy-1 nephritis. J Am Soc Nephrol 14:848-854, 2003
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 848-854
-
-
Clarke, H.C.1
Kocher, H.M.2
Khwaja, A.3
-
25
-
-
0032994257
-
Evidence of a role for Ki-Ras in the stimulated proliferation of renal fibroblasts
-
SHARPE CC, DOCKRELL ME, SCOTT R, et al: Evidence of a role for Ki-Ras in the stimulated proliferation of renal fibroblasts. J Am Soc Nephrol 10:1186-1192, 1999
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 1186-1192
-
-
Sharpe, C.C.1
Dockrell, M.E.2
Scott, R.3
-
26
-
-
0035203194
-
ERK1/2 is required for myoblast proliferation but is dispensable for muscle gene expression and cell fusion
-
JONES NC, FEDOROV YV, ROSENTHAL RS, OLWIN BB: ERK1/2 is required for myoblast proliferation but is dispensable for muscle gene expression and cell fusion. J Cell Physiol 186:104-115, 2001
-
(2001)
J Cell Physiol
, vol.186
, pp. 104-115
-
-
Jones, N.C.1
Fedorov, Y.V.2
Rosenthal, R.S.3
Olwin, B.B.4
-
27
-
-
0034970113
-
In vitro evidence for differential involvement of CTGF, TGFbeta, and PDGF-BB in mesangial response to injury
-
BLOM IE, VAN DIJK AJ, WIETEN L, et al: In vitro evidence for differential involvement of CTGF, TGFbeta, and PDGF-BB in mesangial response to injury. Nephrol Dial Transplant 16:1139-1148, 2001
-
(2001)
Nephrol Dial Transplant
, vol.16
, pp. 1139-1148
-
-
Blom, I.E.1
Van Dijk, A.J.2
Wieten, L.3
-
28
-
-
0028246311
-
Expression of platelet-derived growth factor receptors in normal and diseased human kidney. An immunohistochemistry and in situ hybridization study
-
GESUALDO L, DI PAOLO S, MILANI S, et al: Expression of platelet-derived growth factor receptors in normal and diseased human kidney. An immunohistochemistry and in situ hybridization study. J Clin Invest 94:50-58, 1994
-
(1994)
J Clin Invest
, vol.94
, pp. 50-58
-
-
Gesualdo, L.1
Di Paolo, S.2
Milani, S.3
-
29
-
-
0034119307
-
The role of vasoactive compounds, growth factors and cytokines in the progression of renal disease
-
KLAHR S, MORRISSEY JJ: The role of vasoactive compounds, growth factors and cytokines in the progression of renal disease. Kidney Int 75(Suppl):S7-14, 2000
-
(2000)
Kidney Int
, vol.75
, Issue.SUPPL.
-
-
Klahr, S.1
Morrissey, J.J.2
-
30
-
-
0034716460
-
Prenylation inhibitors in renal disease
-
KHWAJA A, O'CONNOLLY J, HENDRY BM: Prenylation inhibitors in renal disease. Lancet 355:741-744, 2000
-
(2000)
Lancet
, vol.355
, pp. 741-744
-
-
Khwaja, A.1
O'Connolly, J.2
Hendry, B.M.3
-
31
-
-
0042887042
-
The emerging role of lysophosphatidic acid in cancer
-
MILLS GB, MOOLENAAR WH: The emerging role of lysophosphatidic acid in cancer. Nat Rev Cancer 3:582-591, 2003
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 582-591
-
-
Mills, G.B.1
Moolenaar, W.H.2
-
32
-
-
0035829731
-
Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation
-
PAZ A, HAKLAI R, ELAD-SFADIA G, et al: Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation. Oncogene 20:7486-7493, 2001
-
(2001)
Oncogene
, vol.20
, pp. 7486-7493
-
-
Paz, A.1
Haklai, R.2
Elad-Sfadia, G.3
-
33
-
-
0013227128
-
A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice
-
WEISZ B, GIEHL K, GANA-WEISZ M, et al: A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice. Oncogene 18:2579-2588, 1999
-
(1999)
Oncogene
, vol.18
, pp. 2579-2588
-
-
Weisz, B.1
Giehl, K.2
Gana-Weisz, M.3
-
34
-
-
0031590420
-
The Ras antagonist S-farnesylthiosalicylic acid induces inhibition of MAPK activation
-
GANA-WEISZ M, HAKLAI R, MARCIANO D, et al: The Ras antagonist S-farnesylthiosalicylic acid induces inhibition of MAPK activation. Biochem Biophys Res Commun 239:900-904, 1997
-
(1997)
Biochem Biophys Res Commun
, vol.239
, pp. 900-904
-
-
Gana-Weisz, M.1
Haklai, R.2
Marciano, D.3
-
36
-
-
0033604620
-
Bioactive lysophospholipids and their G protein-coupled receptors
-
MOOLENAAR WH: Bioactive lysophospholipids and their G protein-coupled receptors. Exp Cell Res 253:230-238, 1999
-
(1999)
Exp Cell Res
, vol.253
, pp. 230-238
-
-
Moolenaar, W.H.1
-
37
-
-
0036533441
-
Farnesyl thiosalicylic acid inhibits the growth of melanoma cells through a combination of cytostatic and pro-apoptotic effects
-
SMALLEY KS, EISEN TG: Farnesyl thiosalicylic acid inhibits the growth of melanoma cells through a combination of cytostatic and pro-apoptotic effects. Int J Cancer 98:514-522, 2002
-
(2002)
Int J Cancer
, vol.98
, pp. 514-522
-
-
Smalley, K.S.1
Eisen, T.G.2
-
39
-
-
0141788346
-
STI-571: An anticancer protein-tyrosine kinase inhibitor
-
ROSKOSKI R, JR.: STI-571: An anticancer protein-tyrosine kinase inhibitor. Biochem Biophys Res Commun 309:709-717, 2003
-
(2003)
Biochem Biophys Res Commun
, vol.309
, pp. 709-717
-
-
Roskoski Jr., R.1
-
40
-
-
0035074267
-
PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis
-
GILBERT RE, KELLY DJ, MCKAY T, et al: PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis. Kidney Int 59:1324-1332, 2001
-
(2001)
Kidney Int
, vol.59
, pp. 1324-1332
-
-
Gilbert, R.E.1
Kelly, D.J.2
McKay, T.3
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