ERK1/2 is required for myoblast proliferation but is dispensable for muscle gene expression and cell fusion

Journal of Cellular Physiology

Volumn 186, Issue 1, 2001, Pages 104-115

  Jones, Nathan C ^a   Fedorov, Yuri V ^a   Rosenthal, R Scott ^a,b   Olwin, Bradley B ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b BAYER CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL FUSION; CELL PROLIFERATION; GENE EXPRESSION; GENE OVEREXPRESSION; MITOSIS; MUSCLE GROWTH; MYOBLAST; PRIORITY JOURNAL; REPORTER GENE; SATELLITE CELL; SKELETAL MUSCLE; TISSUE REPAIR;

ANIMALS; BUTADIENES; CELL DIVISION; CELL FUSION; CELL LINE; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; G1 PHASE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENES, REPORTER; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MITOSIS; MUSCLE, SKELETAL; NITRILES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-RAF; S PHASE;

EID: 0035203194     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4652(200101)186:1<104::AID-JCP1015>3.0.CO;2-0     Document Type: Article

References (47)

1. Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases
2. Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase
3. Differential activation of mitogen-activated protein kinase in response to basic fibroblast growth factor in skeletal muscle cells
4. Growth factor control of skeletal muscle differentiation: Commitment to terminal differentiation occurs in G1 phase and is repressed by fibroblast growth factor
5. The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways
6. Single-cell analysis of regulatory gene expression in quiescent and activated mouse skeletal muscle satellite cells
7. Gene expression in wild-type and MyoD-null satellite cells: Regulation of activation, proliferation, and myogenesis
8. MyoD-/-satellite cells in single fiber culture are differentiation defective and MRF4 deficient
9. A synthetic inhibitor of the mitogen-activated protein kinase cascade
10. Identification of a novel inhibitor of mitogen-activated protein kinase kinase
11. Regulation of myogenesis by fibroblast growth factors requires beta-gamma subunits of pertussis texin-sensitive G proteins
12. Loss of FGF receptor signaling reduces skeletal muscle mass and disrupts myofiber organization in the developing limb
13. A role for FGF-6 in skeletal muscle regeneration
14. Mitogen-activated protein kinase pathway is involved in the differentiation of muscle cells
15. An analysis of MEK1 signaling in cell proliferation and transformation
16. Differentially expressed fibroblast growth factors regulate skeletal muscle development through autocrine and paracrine mechanisms
17. Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1
18. Shc and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells
19. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway
20. A requirement for fibroblast growth factor in regulation of skeletal muscle growth and differentiation cannot be replaced by activation of platelet-derived growth factor signaling pathways
21. The FGF receptor-1 tyrosine kinase domain regulates myogenesis but is not sufficient to stimulate proliferation
22. Signal transduction through MAP kinase cascades
23. EGF responsiveness and receptor regulation in normal and differentiation-defective mouse myoblasts
24. Myogenic differentiation in permanent clonal myoblast cell lines: Regulation by macromolecular growth factors in the culture medium
25. Transformation of mammalian cells by constitutively active MAP kinase kinase
26. Satellite cell of skeletal muscle fibers
27. Stimulation of C2C12 myoblast growth by basic fibroblast growth factor and insulin-like growth factor 1 can occur via mitogen-activated protein kinase-dependent and -independent pathways
28. Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction
29. Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis
30. A typrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1
31. Satellite cells as the source of nuclei in muscles of growing rats
32. A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation
33. Identification of the fibroblast growth factor receptor of Swiss 3T3 cells and mouse skeletal muscle myoblasts
34. 2+ flux but not mitogenesis
35. Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy
36. Mitogen-activated protein kinase pathways
37. Skeletal muscle satellite cells
38. Clonal analysis of vertebrate myogenesis. VIII. Fibroblasts growth factor (FGF)-dependent and FGF-independent muscle colony types during chick wing development
39. Activation of the MKK/ERK pathway during somatic cell mitosis: Direct interactions of active ERK with kinetochores and regulation of the mitotic 3F3/2 phosphoantigen
40. Definition of the human raf amino-terminal regulatory region by deletion mutagenesis
41. Association of a 85-kDa serine kinase with activated fibroblast growth factor receptor-4
42. Broadly expressed SNT-like proteins link FGF receptor stimulation to activators of Ras
43. Mitogen-activated protein kinase kinase (MEK) activity is required for inhibition of skeletal muscle differentiation by insulin-like growth factor 1 or fibroblast growth factor 2
44. Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins
45. In vivo signal transduction pathway reporting systems
46. Fibroblast growth factor promotes recruitment of skeletal muscle satellite cells in young and old rats
47. Active MAP kinase in mitosis: Localization at kinetochores and association with the motor protein CENP-E