Coenzyme Q10 improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus

Diabetologia

Volumn 45, Issue 3, 2002, Pages 420-426

  Watts, G F ^a   Playford, D A ^a   Croft, K D ^a   Ward, N C ^a   Mori, T A ^a   Burke, V ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Coenzyme Q10; Diabetes; Endothelial function; Nitric oxide

Indexed keywords

ANTIOXIDANT; GLYCERYL TRINITRATE; ISOPROSTANE; NITRIC OXIDE; OXYGEN RADICAL; UBIDECARENONE;

ADULT; AGED; ARTERY DIAMETER; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; BLOOD LEVEL; BRACHIAL ARTERY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DYSLIPIDEMIA; FEMALE; HUMAN; HYPEREMIA; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ANTIOXIDANTS; BLOOD PRESSURE; BRACHIAL ARTERY; CHOLESTEROL; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; HYPEREMIA; LIPOPROTEINS; MALE; MIDDLE AGED; PLACEBOS; REGIONAL BLOOD FLOW; TRIGLYCERIDES; UBIQUINONE; VASODILATION;

EID: 0036207652     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-001-0760-y     Document Type: Article

References (48)

1. The mystery of diabetes and atherosclerosis. Time for a new plot
2. The role of endothelium in cardiovascular homeostasis and diseases
3. Dysfunction of vascular endothelium in diabetes mellitus
4. Endothelial dysfunction in diabetes
5. Oxidative stress and diabetic vascular complications
6. Dyslipoproteinaemia and hyperoxidative stress in the pathogenesis of endothelial dysfunction in NIDDM: An hypothesis
7. Dietary and pharmacological antioxidants in atherosclerosis
8. Vitamin E supplementation and cardiovascular events in high-risk patients
9. Vitamin E supplementation improves endothelial function in type 1 diabetes mellitus: A randomized, placebo-controlled study
10. Effect of oral vitamin E (α-tocopheral) supplementation in vascular endothelial function in type 2 diabetes mellitus
11. Oral treatment with an antioxidant (raxofelast) reduces oxidative stress and improves endothelial function in men with Type II diabetes
12. Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin dependent diabetes mellitus
13. The participation of coenzyme Q in free radical production and anti-oxidation
14. Coenzyme Q versus hypertension: Does CoQ decrease endothelial superoxide generation?
15. Ubiquinol-10 protects human low-density lipoprotein more efficiently against lipid peroxidation than does α-tocopherol
16. Cosupplementation with coenzyme Q prevents the prooxidant effect of α-tocopherol and increase the resistance of LDL to transition metal-dependent oxidation initiation
17. Pathogenesis of NIDDM: A balanced overview
18. Can correction of sub-optimal coenzyme Q staus improve β-cell function in type II diabetes?
19. 10 alpha-tocopherol, and free cholesterol levels in sera from diabetic patients
20. 7 treatment on blood sugar and ketone bodies of diabetics
21. 10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease
22. A role for reduced coenzyme Q in atherosclerosis
23. Improved analysis of brachial artery ultrasound using a novel edge detection software system
24. Simultaneous determination of tocopherols, ubiquinols and ubiquinones in blood, plasma, tissue homogenates and subcellular fractions
25. An improved method for the measurement of urinary and plasma F2-isoprostanes using Gas Chromatography Mass Spectrometry
26. Oxygen-radical absorbance capacity assay for antioxidants
27. Endothelium-dependent and independent vasodilation studied at normoglycaemia in Type I diabetes mellitus with and without microalbuminuria
28. 2α levels are elevated in individuals with non-insulin dependent diabetes mellitus
29. F2α and platelet activation in diabetes mellitus: Effects of improved metabolic control and vitamin E supplementation
30. Review of alterations in endothelial nitric oxide production in diabetes: Protective effect of arginine on endothelial dysfunction
31. Antioxidant status and lipid peroxidation in type 2 diabetes mellitus with and without complications
32. Vitamin E ingestion does not improve arterial endothelial dysfunction in older adults
33. Beneficial effects of α-lipoic acid and ascorbic acid on endothelium-dependent, nitric oxide-mediated vasodilation in diabetic patients: Relation to parameters of oxidative stress
34. Close relation of endothelial function in the human coronary and peripheral circulations
35. Late prognostic value of flow-mediated dilation in the brachial artery of patients with chest pain
36. Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase
37. Inhibitory effects of low-density lipoproteins from men with type 2 diabetes or endothelium-dependent relaxation
38. The relationship between post-prandial lipaemia, endothelial function and oxidative stress in healthy individuals and patients with type 2 diabetes
39. 10 administration on metabolic control in patients with type 2 diabetes mellitus
40. 10) treatment on glycaemic control, insulin requirements and well-being in patients with Type 1 diabetes mellitus
41. Endogenous nitric oxide synthase inhibitor: A novel marker of atherosclerosis
42. Ascorbic acid enhances endothelial nitric oxide activity by increasing intracellular tetrahydrobioterin
43. Glutathione reverses endothelial dysfunction and improves nitric oxide bioavailability
44. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
45. Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo
46. Hyperglycaemia rapidly suppresses flow-mediated endothelium-dependent vasodilation of brachial artery
47. Improved endothelial function with metformin in type 2 diabetes mellitus