Zn2+ inhibits mitochondrial movement in neurons by phosphatidylinositol 3-kinase activation

Journal of Neuroscience

Volumn 25, Issue 41, 2005, Pages 9507-9514

  Malaiyandi, Latha M ^a   Honick, Anthony S ^a   Rintoul, Gordon L ^a   Wang, Qiming J ^a   Reynolds, Ian J ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Green fluorescent protein; Mitochondrial membrane potential; Organelle transport; Oxidative stress; Signal transduction; Wortmannin

Indexed keywords

GREEN FLUORESCENT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; WORTMANNIN; ZINC ION; CHLORIDE; DIVALENT CATION; ZINC; ZINC CHLORIDE; ZINC DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL LEVEL; CELL VIABILITY; CHELATION; CONTROLLED STUDY; EMBRYO; ENERGY YIELD; ENZYME ACTIVATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NERVE CELL; NERVE CELL LESION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; METABOLISM; NERVE CELL INHIBITION; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CATIONS, DIVALENT; CELLS, CULTURED; CHLORIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; MITOCHONDRIA; NEURAL INHIBITION; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; ZINC; ZINC COMPOUNDS;

EID: 26844509261     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0868-05.2005     Document Type: Article

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