Cyclic induction of senescence with intermittent AZT treatment accelerates both apoptosis and telomere loss

Breast Cancer Research and Treatment

Volumn 93, Issue 3, 2005, Pages 227-236

  Hyun, Jung Ji ^a   Sun, Young Rha ^a   Hei, Cheul Jeung ^a   Sang, Hwa Yang ^a   Sung, Whan An ^a   Hyun, Cheol Chung ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Apoptosis; hTERT; Senescence; Telomerase; Telomere

Indexed keywords

ISOENZYME; MYC PROTEIN; PROTEIN; PROTEIN MAD1; RNA; TELOMERASE; TELOMERASE ASSOCIATED PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG; ZIDOVUDINE;

APOPTOSIS; ARTICLE; BREAST ADENOCARCINOMA; CANCER GROWTH; CARCINOMA CELL; CELL AGING; CHROMOSOME LOSS; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBUNIT; HUMAN; HUMAN CELL; LOW DRUG DOSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; TELOMERE;

APOPTOSIS; BREAST NEOPLASMS; CELL AGING; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; HUMANS; REVERSE TRANSCRIPTASE INHIBITORS; TELOMERASE; TELOMERE; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; ZIDOVUDINE;

EID: 26644464602     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-005-5156-0     Document Type: Article

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