TRPMs and neuronal cell death

Pflugers Archiv European Journal of Physiology

Volumn 451, Issue 1, 2005, Pages 243-249

  Aarts, Michelle M ^a   Tymianski, Michael ^a  

^a UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Calcium; CNS; Melastatin; Neurodegeneration; Reactive oxygen species; Stroke

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; CALCIUM; GLUCOSE; GLUTAMATE RECEPTOR ANTAGONIST; LANTHANUM; OXYGEN; OXYGEN RADICAL; PROTEIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL MELASTATIN 2; TRANSIENT RECEPTOR POTENTIAL CHANNEL MELASTATIN 7; UNCLASSIFIED DRUG;

APOPTOSIS; BRAIN EDEMA; BRAIN INJURY; CALCIUM HOMEOSTASIS; CELL DEATH; CELL SURVIVAL; ENCEPHALITIS; EXCITOTOXICITY; GENETIC ANALYSIS; HUMAN; HYPOXIA; NERVE CELL; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; REVIEW; SIGNAL TRANSDUCTION;

ANOXIA; CALCIUM; CELL DEATH; CENTRAL NERVOUS SYSTEM DISEASES; GLUCOSE; HUMANS; NEURODEGENERATIVE DISEASES; NEURONS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TRPM CATION CHANNELS;

EID: 26444555458     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-005-1439-x     Document Type: Review

References (59)

1. Olney JW (1969) Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. Science 164:719-721
2. Choi DW (1988) Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. Trends Neurosci 11:465-469
3. Arundine M, Tymianski M (2003) Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium 34:325-337
4. Lipton P (1999) Ischemic cell death in brain neurons. Physiol Rev 79:1431-1568
5. Iadecola C (1997) Bright and dark sides of nitric oxide in ischemic brain injury. Trends Neurosci 20:132-139
6. Chan PH (1994) Oxygen radicals in focal cerebral ischemia. Brain Pathol 4:59-65
7. Dugan LL, Choi DW (1994) Excitotoxicity, free radicals, and cell membrane changes. Ann Neurol 35 (Suppl):S17-S21
8. Dawson VL, Kizushi VM, Huang PL, Snyder SH, Dawson TM (1996) Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice. J Neurosci 16:2479-2487
9. Birmingham K (2002) Future of neuroprotective drugs in doubt. Nat Med 8:5
10. Ikonomidou C, Turski L (2002) Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury? Lancet Neurology 1:383-386
11. Goldberg MP, Weiss JH, Pham PC, Choi DW (1987) N-methyl-D-aspartate receptors mediate hypoxic neuronal injury in cortical culture. J Pharmacol Exp Ther 243:784-791
12. Choi DW, Maulucci-Gedde M, Kriegstein AR (1987) Glutamate neurotoxicity in cortical cell culture. J Neurosci 7:357-368
13. Choi DW, Koh JY, Peters S (1988) Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists. J Neurosci 8:185-196
14. Xiong Z, Lu W, MacDonald JF (1997) Extracellular calcium sensed by a novel cation channel in hippocampal neurons. Proc Natl Acad Sci USA 94:7012-7017
15. 2+-sensing cation current in cultured hippocampal neurons. J Neurophysiol 86:2520-2526
16. Heinemann U, Lux HD, Gutnick MJ (1977) Extracellular free calcium and potassium during paroxysmal activity in the cerebral cortex of the cat. Exp Brain Res 27:237-243
17. Heinemann U, Pumain R (1980) Extracellular calcium activity changes in cat sensorimotor cortex induced by iontophoretic application of aminoacids. Exp Brain Res 40:247-250
18. Hansen AJ, Zeuthen T (1981) Extracellular ion concentrations during spreading depression and ischemia in the rat brain cortex. Acta Physiol Scand 113:437-445
19. Hille B (1992) Ionic channels of excitable membranes 2nd Edn. Sinauer, Sunderland
20. Clapham DE, Runnels LW, Strubing C (2001) The TRP ion channel family. Nat Rev Neurosci 2:387-396
21. Moran MM, Xu H, Clapham DE (2004) TRP ion channels in the nervous system. Curr Opin Neurobiol 14:362-369
22. i. Proc Natl Acad Sci USA 100:15166-15171
23. Wehage E, Eisfeld J, Heiner I, Jungling E, Zitt C, Luckhoff A (2002) Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose. J Biol Chem 277:23150-23156
24. 2+-permeable channel activated by changes in redox status confers susceptibility to cell death. Mol Cell 9:163-173
25. Hardie RC, Raghu P (2001) Visual transduction in Drosophila. Nature 413:186-193
26. Agam K, von Campenhausen M, Levy S, Ben Ami HC, Cook B, Kirschfeld K, Minke B (2000) Metabolic stress reversibly activates the Drosophila light-sensitive channels TRP and TRPL in vivo. J Neurosci 20:5748-5755
27. Minke B, Agam K (2003) TRP gating is linked to the metabolic state and maintenance of the Drosophila photoreceptor cells. Cell Calcium 33:395-408
28. 2+ channel causes massive degeneration of photoreceptors. J Biol Chem 277:33884-33889
29. Yoon J, Ben Ami HC, Hong YS, Park S, Strong LL, Bowman J, Geng C, Baek K, Minke B, Pak WL (2000) Novel mechanism of massive photoreceptor degeneration caused by mutations in the trp gene of Drosophila. J Neurosci 20:649-659
30. Balzer M, Lintschinger B, Groschner K (1999) Evidence for a role of Trp proteins in the oxidative stress-induced membrane conductances of porcine aortic endothelial cells. Cardiovasc Res 42:543-549
31. Nadler MJ, Hermosura MC, Inabe K, Perraud AL, Zhu Q, Stokes AJ, Kurosaki T, Kinet JP, Penner R, Scharenberg AM, Fleig A (2001) LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability. Nature 411:590-595
32. Monteilh-Zoller MK, Hermosura MC, Nadler MJ, Scharenberg AM, Penner R, Fleig A (2003) TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions. J Gen Physiol 121:49-60
33. 2+ homeostasis by TRPM7. Cell 114:191-200
34. He Y, Yao G, Savoia C, Touyz RM (2005) Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II. Circ Res 96:207-215
35. Chubanov V, Waldegger S, Mederos y Schnitzler M, Vitzthum H, Sassen MC, Seyberth HW, Konrad M, Gudermann T (2004) Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia. Proc Natl Acad Sci USA 101:2894-2899
36. 2+ entry pathway in human retinoblastoma cells. J Pharmacol Sci 95:403-419
37. Schmitz C, Perraud AL, Fleig A, Scharenberg AM (2004) Dual-function ion channel/protein kinases: novel components of vertebrate magnesium regulatory mechanisms. Pediatr Res 55:734-737
38. Takezawa R, Schmitz C, Demeuse P, Scharenberg AM, Penner R, Fleig A (2004) Receptor-mediated regulation of the TRPM7 channel through its endogenous protein kinase domain. Proc Natl Acad Sci USA 101:6009-6014
39. Ryazanova LV, Dorovkov MV, Ansari A, Ryazanov AG (2004) Characterization of the protein kinase activity of TRPMV/ChaK1, a protein kinase fused to the transient receptor potential ion channel. J Biol Chem 279:3708-3716
40. Dorovkov MV, Ryazanov AG (2004) Phosphorylation of annexin I by TRPM7 channel-kinase. J Biol Chem 279:50643-50646
41. Aarts M, Iihara K, Wei WL, Xiong ZG, Arundine M, Cerwinski W, MacDonald JF, Tymianski M (2003) A key role for TRPM7 channels in anoxic neuronal death. Cell 115:863-877
42. Feighan D, MacVicar BA (2004) A Gadolinium-sensitive cation channel contributes to ischemic-like excitotoxicity in brain slices in addition to NMDA and kainate receptor activation. 2004 Abstract Viewer/Itinerary Planner Washington DC: Society for Neuroscience 99.16 http://sfn.scholarone.com/ itin2004/index.html
43. 2+ influx elicited by glutamate: role in neuronal death. Mol Pharmacol 36:106-112
44. i. J Neurosci 20:2094-2103
45. Rego AC, Ward MW, Nicholls DG (2001) Mitochondria control AMPA/kainate receptor-induced cytoplasmic calcium deregulation in rat cerebellar granule cells. J Neurosci 21:1893-1901
46. Hartley DM, Choi DW (1989) Delayed rescue of N-methyl-D-aspartate receptor-mediated neuronal injury in cortical culture. J Pharmacol Exp Ther 250:752-758
47. 2+ overload indicates early neuronal injury which precedes staining with viability indicators. Brain Res 607:319-323
48. 2+ sequestration/extrusion mechanisms following excitotoxic glutamate exposure. Brain Res 894:56-67
49. Chen QX, Perkins KL, Choi DW, Wong RK (1997) Secondary activation of a cation conductance is responsible for NMDA toxicity in acutely isolated hippocampal neurons. J Neurosci 17:4032-4036
50. 3+ in cultured cortical neurones. J Neurochem 91:471-483
51. Rowland KC, Connor JA, Shuttleworth CWR (2004) Mechanisms underlying the initiation of sustained inward currents in CA1 hippocampal neurons. 2004 Abstract Viewer/Itinerary Planner Washington, DC: Society for Neuroscience, 2004 Online 342.4. http://sfn.scholarone.com/itin2004/index.html
52. Jiang X, Newell EW, Schlichter LC (2003) Regulation of a TRPM7-like current in rat brain microglia. J Biol Chem 278:42867-42876
53. 2 hydrolysis. Nat Cell Biol 4:329-336
54. Choi DW, Koh JY (1998) Zinc and brain injury. Annu Rev Neurosci 21: 347-375
55. Harteneck C, Kuchta SN, Huber A, Paulsen R, Schultz G (2002) The PDZ scaffold protein INAD abolishes apparent store-dependent regulation of the light-activated cation channel TRP. FASEB J 16:1668-1670
56. Li HS, Montell C (2000) TRP and the PDZ protein, INAD, form the core complex required for retention of the signalplex in Drosophila photoreceptor cells. J Cell Biol 150:1411-1422
57. Tang Y, Tang J, Chen Z, Trost C, Flockerzi V, Li M, Ramesh V, Zhu MX (2000) Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF. J Biol Chem 275:37559-37564
58. Mery L, Strauss B, Dufour JF, Krause KH, Hoth M (2002) The PDZ-interacting domain of TRPC4 controls its localization and surface expression in HEK293 cells. J Cell Sci 115:3497-3508
59. 2+ channel by INAD in Drosophila photoreceptors. Neuron 16:991-998