-
2
-
-
0036435888
-
Molecular and biochemical markers in colorectal cancer
-
McDermott U, Longley DB, Johnston PG. Molecular and biochemical markers in colorectal cancer. Ann Oncol 2002; 235-45.
-
(2002)
Ann Oncol
, pp. 235-245
-
-
McDermott, U.1
Longley, D.B.2
Johnston, P.G.3
-
3
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler K, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996; 87:159-170.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.1
Vogelstein, B.2
-
4
-
-
23944469938
-
Targeting signal transduction pathways in colorectal cancer - More than skin deep
-
In press
-
Cohen SJ, Cohen RB, Meropol NJ. Targeting signal transduction pathways in colorectal cancer - More than skin deep. J Clin Oncol 2005; In press.
-
(2005)
J Clin Oncol
-
-
Cohen, S.J.1
Cohen, R.B.2
Meropol, N.J.3
-
5
-
-
0029553183
-
An overview of the epithelio-mesenchymal transformation
-
Hay ED. An overview of the epithelio-mesenchymal transformation. Acta Anat 1995; 154:8-20.
-
(1995)
Acta Anat
, vol.154
, pp. 8-20
-
-
Hay, E.D.1
-
6
-
-
0034798707
-
Leaving the neighborhood: Molecular mechanisms involved during epithelial-mesenchymal transition
-
Savagner P. Leaving the neighborhood: Molecular mechanisms involved during epithelial-mesenchymal transition. BioEssays 2001; 23:912-923.
-
(2001)
BioEssays
, vol.23
, pp. 912-923
-
-
Savagner, P.1
-
7
-
-
0344845003
-
Epithelial-mesenchymal transitions in development and pathologies
-
Thiery JP. Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol 2003; 15:740-6.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 740-746
-
-
Thiery, J.P.1
-
8
-
-
0035906987
-
Epithelial mesenchymal interactions in cancer and development
-
Arias AM. Epithelial mesenchymal interactions in cancer and development. Cell 2001; 105:425-31.
-
(2001)
Cell
, vol.105
, pp. 425-431
-
-
Arias, A.M.1
-
9
-
-
0037572319
-
Tumor necrosis factor-α stimulates the epithelial to mesenchymal transition of human colonic organoids
-
Bates RC, Mercurio AM. Tumor necrosis factor-α stimulates the epithelial to mesenchymal transition of human colonic organoids. Mol Biol Cell 2003; 14:1790-800.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 1790-1800
-
-
Bates, R.C.1
Mercurio, A.M.2
-
10
-
-
0141838134
-
Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids
-
Bates RC, Goldsmith JD, Bachelder RE, Brown C, Shibuya M, Oettgen P, Mercurio AM. Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids. Curr Biol 2003; 13:1721-7.
-
(2003)
Curr Biol
, vol.13
, pp. 1721-1727
-
-
Bates, R.C.1
Goldsmith, J.D.2
Bachelder, R.E.3
Brown, C.4
Shibuya, M.5
Oettgen, P.6
Mercurio, A.M.7
-
11
-
-
14944348752
-
Transcriptional activation of integrin β6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma
-
Bates RC, Bellovin DI, Brown C, Maynard E, Wu B, Kawakatsu H, Sheppard D, Oettgen P. Mercurio AM. Transcriptional activation of integrin β6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma. J Clin Invest 2005; 115:339-47.
-
(2005)
J Clin Invest
, vol.115
, pp. 339-347
-
-
Bates, R.C.1
Bellovin, D.I.2
Brown, C.3
Maynard, E.4
Wu, B.5
Kawakatsu, H.6
Sheppard, D.7
Oettgen, P.8
Mercurio, A.M.9
-
12
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nature Rev Cancer 2002; 2:442-54.
-
(2002)
Nature Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
13
-
-
0026770377
-
Integrins: Versatility, modulation, and signaling in cell adhesion
-
Hynes RO. Integrins: Versatility, modulation, and signaling in cell adhesion. Cell 1992; 69:11-25.
-
(1992)
Cell
, vol.69
, pp. 11-25
-
-
Hynes, R.O.1
-
16
-
-
0026660349
-
Characterization of the integrin αvβ6 as a fibronectin-binding protein
-
Busk M, Pytela R, Sheppard D. Characterization of the integrin αvβ6 as a fibronectin-binding protein. J Biol Chem 1992; 267:5790-6.
-
(1992)
J Biol Chem
, vol.267
, pp. 5790-5796
-
-
Busk, M.1
Pytela, R.2
Sheppard, D.3
-
17
-
-
0029796370
-
Differential effects of the integrins alpha9beta1, alphavbeta3, and alphavbeta6 on cell proliferative responses to tenascin. Roles of the beta subunit extracellular and cytoplasmic domains
-
Yokosaki Y, Monis H, Chen J, Sheppard D. Differential effects of the integrins alpha9beta1, alphavbeta3, and alphavbeta6 on cell proliferative responses to tenascin. Roles of the beta subunit extracellular and cytoplasmic domains. J Biol Chem 1996; 271:24144-50.
-
(1996)
J Biol Chem
, vol.271
, pp. 24144-24150
-
-
Yokosaki, Y.1
Monis, H.2
Chen, J.3
Sheppard, D.4
-
18
-
-
0027234361
-
Restricted distribution of integrin beta 6 mRNA in primate epithelial tissues
-
Breuss JM, Gillett N, Lu L, Sheppard D, Pytela R. Restricted distribution of integrin beta 6 mRNA in primate epithelial tissues. J Histochem Cytochem 1993; 41:1521-7.
-
(1993)
J Histochem Cytochem
, vol.41
, pp. 1521-1527
-
-
Breuss, J.M.1
Gillett, N.2
Lu, L.3
Sheppard, D.4
Pytela, R.5
-
19
-
-
0028978232
-
Expression of the β6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling
-
Breuss JM, Gallo J, DeLisser HM, Klimanskaya IV, Folkesson HG, Pittet JF, Nishimura SL, Aldape K, Landers D, Carpenter W, Gillett N, Sheppard D, Matthay MA, Albelda SM, Kramer RH, Pytela R. Expression of the β6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling. J Cell Sci 1995; 108:2241-51.
-
(1995)
J Cell Sci
, vol.108
, pp. 2241-2251
-
-
Breuss, J.M.1
Gallo, J.2
Delisser, H.M.3
Klimanskaya, I.V.4
Folkesson, H.G.5
Pittet, J.F.6
Nishimura, S.L.7
Aldape, K.8
Landers, D.9
Carpenter, W.10
Gillett, N.11
Sheppard, D.12
Matthay, M.A.13
Albelda, S.M.14
Kramer, R.H.15
Pytela, R.16
-
20
-
-
0034024666
-
Expression of alpha(v)beta6 integrin in oral leukoplakia
-
Hamidi S, Salo T, Kainulainen T, Epstein J, Lerner K, Larjava H. Expression of alpha(v)beta6 integrin in oral leukoplakia. Br J Cancer 2000; 82:1433-40.
-
(2000)
Br J Cancer
, vol.82
, pp. 1433-1440
-
-
Hamidi, S.1
Salo, T.2
Kainulainen, T.3
Epstein, J.4
Lerner, K.5
Larjava, H.6
-
21
-
-
0036076481
-
Tenascin and β6 integrin are overexpressed in floor of mouth in situ carcinomas and invasive squamous cell carcinomas
-
Regezi JA, Ramos DM, Pytela R, Dekker NP, Jordan RCK. Tenascin and β6 integrin are overexpressed in floor of mouth in situ carcinomas and invasive squamous cell carcinomas. Oral Oncol 2002; 38:332-6.
-
(2002)
Oral Oncol
, vol.38
, pp. 332-336
-
-
Regezi, J.A.1
Ramos, D.M.2
Pytela, R.3
Dekker, N.P.4
Jordan, R.C.K.5
-
22
-
-
0035902141
-
The microenvironment of the tumor-host interface
-
Liotta L, Kohn EC. The microenvironment of the tumor-host interface. Nature 2001; 411:375-9.
-
(2001)
Nature
, vol.411
, pp. 375-379
-
-
Liotta, L.1
Kohn, E.C.2
-
23
-
-
0035170731
-
Reactive stroma in prostate cancer progression
-
Tuxhorn JA, Ayala GE, Rowley DR. Reactive stroma in prostate cancer progression. J Urol 2001; 166:2472-83.
-
(2001)
J Urol
, vol.166
, pp. 2472-2483
-
-
Tuxhorn, J.A.1
Ayala, G.E.2
Rowley, D.R.3
-
24
-
-
0031817391
-
Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: Implications for tumor invasion
-
Portella G, Cumming SA, Liddell J, Cui W, Ireland H, Akhurst RH, Balmain A. Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: Implications for tumor invasion. Cell Growth Diff 1998; 9:393-404.
-
(1998)
Cell Growth Diff
, vol.9
, pp. 393-404
-
-
Portella, G.1
Cumming, S.A.2
Liddell, J.3
Cui, W.4
Ireland, H.5
Akhurst, R.H.6
Balmain, A.7
-
25
-
-
0034666839
-
Raf induces TGFβ production while blocking its apoptotic but not invasive responses: A mechanism leading to increased malignancy in epithelial cells
-
Lehmann K, Janda E, Pierreux CE, Rytomaa M, Schulze A, McMahon M, Hill CS, Downward J. Raf induces TGFβ production while blocking its apoptotic but not invasive responses: A mechanism leading to increased malignancy in epithelial cells. Genes Dev 2000; 14:2610-22.
-
(2000)
Genes Dev
, vol.14
, pp. 2610-2622
-
-
Lehmann, K.1
Janda, E.2
Pierreux, C.E.3
Rytomaa, M.4
Schulze, A.5
McMahon, M.6
Hill, C.S.7
Downward, J.8
-
26
-
-
0035185853
-
Transforming growth factor-β1 mediates epithelial to mesenchymal transdifferentiation through a Rho-A-dependent mechanism
-
Bhowmick NA, Ghiassi M, Bakin A, Aakre M, Lundquist CA, Engel ME, Arteaga CL, Moses HL. Transforming growth factor-β1 mediates epithelial to mesenchymal transdifferentiation through a Rho-A-dependent mechanism. Mol Biol Cell 2001; 12:27-36.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 27-36
-
-
Bhowmick, N.A.1
Ghiassi, M.2
Bakin, A.3
Aakre, M.4
Lundquist, C.A.5
Engel, M.E.6
Arteaga, C.L.7
Moses, H.L.8
-
27
-
-
0035872426
-
Transforming growth factor β1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular-signal regulated kinase 2 activation
-
Ellenrieder V, Hendler SF, Boeck W, Seufferlein T, Menke A, Ruhland C, Adler G, Gress TM. Transforming growth factor β1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular-signal regulated kinase 2 activation. Cancer Res 2001; 61:4222-8.
-
(2001)
Cancer Res
, vol.61
, pp. 4222-4228
-
-
Ellenrieder, V.1
Hendler, S.F.2
Boeck, W.3
Seufferlein, T.4
Menke, A.5
Ruhland, C.6
Adler, G.7
Gress, T.M.8
-
28
-
-
0029662049
-
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
-
Oft M, Peli J, Rudaz C, Schwarz H, Beug H, Reichmann E. TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev 1996; 10:2462-77.
-
(1996)
Genes Dev
, vol.10
, pp. 2462-2477
-
-
Oft, M.1
Peli, J.2
Rudaz, C.3
Schwarz, H.4
Beug, H.5
Reichmann, E.6
-
29
-
-
0027930489
-
Colon carcinoma cells switch their response to transforming growth factor beta 1 with tumor progression
-
Hsu S, Huang F, Hafez M, Winawer S, Friedman E. Colon carcinoma cells switch their response to transforming growth factor beta 1 with tumor progression. Cell Growth Diff 1994; 5:267-75.
-
(1994)
Cell Growth Diff
, vol.5
, pp. 267-275
-
-
Hsu, S.1
Huang, F.2
Hafez, M.3
Winawer, S.4
Friedman, E.5
-
30
-
-
0033565626
-
Transforming growth factor beta 1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis
-
Engle SJ, Hoying JB, Boivin GP, Ormsby I, Gartside PS, Doetschman T. Transforming growth factor beta 1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis. Cancer Res 1999; 59:3379-86.
-
(1999)
Cancer Res
, vol.59
, pp. 3379-3386
-
-
Engle, S.J.1
Hoying, J.B.2
Boivin, G.P.3
Ormsby, I.4
Gartside, P.S.5
Doetschman, T.6
-
31
-
-
0032547895
-
TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis
-
Oft M, Heider KH, Berg H. TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis. Curr Biol 1998; 8:1243-52.
-
(1998)
Curr Biol
, vol.8
, pp. 1243-1252
-
-
Oft, M.1
Heider, K.H.2
Berg, H.3
-
32
-
-
0033524949
-
The integrin αvβ6 binds and activates latent TGFβ1: A mechanism for regulating pulmonary inflammation and fibrosis
-
Munger JS, Huang X, Kawakatsu H, Griffiths MJ, Dalton SL, Wu J, Pittet JF, Kaminski N, Garat C, matthay MA, Rifkin DB, Sheppard D. The integrin αvβ6 binds and activates latent TGFβ1: A mechanism for regulating pulmonary inflammation and fibrosis. Cell 1999; 96:319-28.
-
(1999)
Cell
, vol.96
, pp. 319-328
-
-
Munger, J.S.1
Huang, X.2
Kawakatsu, H.3
Griffiths, M.J.4
Dalton, S.L.5
Wu, J.6
Pittet, J.F.7
Kaminski, N.8
Garat, C.9
Matthay, M.A.10
Rifkin, D.B.11
Sheppard, D.12
-
33
-
-
2142641698
-
Phase II trial of cetuximab in patients with refractory colorectal cancer that express the epidermal growth factor receptor
-
Saltz LB, Meropol NJ, Loehrer Sr PJ, Needle MN, Kopit J, Mayer RJ. Phase II trial of cetuximab in patients with refractory colorectal cancer that express the epidermal growth factor receptor. J Clin Oncol 2004; 22:1201-8.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1201-1208
-
-
Saltz, L.B.1
Meropol, N.J.2
Loehrer Sr., P.J.3
Needle, M.N.4
Kopit, J.5
Mayer, R.J.6
-
34
-
-
2142640271
-
Targeting the epidermal growth factor receptor: An important incremental step in the battle against colorectal cancer
-
Ellis LM, Hoff PM. Targeting the epidermal growth factor receptor: An important incremental step in the battle against colorectal cancer. J Clin Oncol 2004; 22:1177-9.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1177-1179
-
-
Ellis, L.M.1
Hoff, P.M.2
-
35
-
-
17144386589
-
Epithelial-mesenchymal transition: NF-κB takes center stage
-
Huber MA, Beug H, Wirth T. Epithelial-mesenchymal transition: NF-κB takes center stage. Cell Cycle 2004; 3:1477-80.
-
(2004)
Cell Cycle
, vol.3
, pp. 1477-1480
-
-
Huber, M.A.1
Beug, H.2
Wirth, T.3
|