Virtual reality of stem cell transplantation to repair injured myocardium

Journal of Cellular Biochemistry

Volumn 95, Issue 5, 2005, Pages 869-874

  Lum, Lawrence G ^a,c   Padbury, James F ^a   Davol, Pamela A ^a   Lee, Randall J ^b  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ROGER WILLIAMS MEDICAL CENTER   (United States)

Author keywords

Adhesion molecules; Animal model; Bispecific antibodies; Myocardial ischemia; Transplantation

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; EMBRYONIC STEM CELL; HEART; HEART MUSCLE INJURY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER; LUNG; MOUSE; MUSCLE; NERVE; NONHUMAN; PANCREAS; PRIORITY JOURNAL; REVIEW; SKIN; STEM CELL TRANSPLANTATION; TISSUE REGENERATION; TISSUE REPAIR; VIRTUAL REALITY;

ANIMALS; HEART; HUMANS; MYOCARDIAL INFARCTION; REGENERATION; STEM CELL TRANSPLANTATION; STEM CELLS;

ANIMALIA;

EID: 26444462174     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20504     Document Type: Review

References (65)

1. Abbott JD, Huang Y, Liu D, Hickey R, Krause DS, Giordano FJ. 2004. Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury. Circulation 110:3300-3305.
2. Aliotta JM, Abedi M, Colvin G, Demers D, Dooner MS, Greer D, Pimentel J, Quesenberry PJ. 2004. Conversion of whole bone marrow cells to cells of the lung after radiation and cardiotoxin injuries. Exp Hematol 32(7):43.
3. Atkins BZ, Hueman MT, Meuchel J, Hutcheson KA, Glower DD, Taylor DA. 1999. Cellular cardiomyoplasty improves diastolic properties of injured heart. J Surg Res 85:234-242.
4. Aversano T, Zhou W, Nedelman M, Nakada M, Weisman H. 1995. A chimeric IgG4 monoclonal antibody directed against CD18 reduces infarct size in a primate model of myocardial ischemia and reperfusion. J Am Coll Cardiol 25:781-788.
5. Badiavas EV, Falanga V. 2003b. Treatment of chronic wounds with bone marrow-derived cells. Arch Dermatol 139:510-516.
6. Badiavas EV, Abedi M, Butmarc J, Falanga V, Quesenberry P. 2003a. Participation of bone marrow derived cells in cutaneous wound healing. J Cell Physiol 196:245-250.
7. Balsam LB, Wagers AJ, Christensen JL, Kofidis T, Weissman IL, Robbins RC. 2004. Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature 428:668-673.
8. Bartholomew A, Sturgeon C, Siatskas M, Ferrer K, McIntosh K, Patil S, Hardy W, Devine S, Ucker D, Deans R, Moseley A, Hoffman R. 2002. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp Hematol 30:42-48.
9. Becker PS, Nilsson SK, Li Z, Berrios VM, Dooner MS, Cooper CL, Hsieh CC, Quesenberry PJ. 1999. Adhesion receptor expression by hematopoietic cell lines and murine progenitors: Modulation by cytokines and cell cycle status. Exp Hematol 27:533-541.
10. Brazelton TR, Rossi FM, Keshet GI, Blau HM. 2000. From marrow to brain: Expression of neuronal phenotypes in adult mice. Science 290:1775-1779.
11. Christman KL, Vardanian AJ, Fang Q, Sievers RE, Fok HH, Lee RJ. 2004. Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium. J Am Coll Cardiol 44:654-660.
12. Grinnemo KH, Mansson A, Dellgren G, Klingberg D, Wardell E, Drvota V, Tammik C, Holgersson J, Ringden O, Sylven C, Le Blanc K. 2004. Xenoreactivity and engraftment of human mesenchymal stem cells transplanted into infarcted rat myocardium. J Thorac Cardiovasc Surg 127:1293-1300.
13. Gumina RJ, Newman PJ, Kenny D, Warltier DC, Gross GJ. 1997. The leukocyte cell adhesion cascade and its role in myocardial ischemia-reperfusion injury. Basic Res Cardiol 92:201-213.
14. Gussoni E, Soneoka Y, Strickland CD, Buzney EA, Khan MK, Flint AF, Kunkel LM, Mulligan RC. 1999. Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature 401:390-394.
15. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. 1981. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 391:85-100.
16. Hartman JC, Anderson DC, Wiltse AL, Lane CL, Rosenbloom CL, Manning AM, Humphrey WR, Wall TM, Shebuski RJ. 1995. Protection of ischemic/reperfused canine myocardium by CL18/6, a monoclonal antibody to adhesion molecule ICAM-1. Cardiovasc Res 30:47-54.
17. Hawkins HK, Entman ML, Zhu JY, Youker KA, Berens K, Dore M, Smith CW. 1996. Acute inflammatory reaction after myocardial ischemic injury and reperfusion. Development and use of a neutrophil-specific antibody. Am J Pathol 148:1957-1969.
18. Irwin MW, Mak S, Mann DL, Qu R, Penninger JM, Yan A, Dawood F, Wen WH, Shou Z, Liu P. 1999. Tissue expression and immunolocalization of tumor necrosis factor-alpha in postinfarction dysfunctional myocardium. Circulation 99:1492-1498.
19. Ishibashi T, Kijima M, Yokoyama K, Shindo J, Nagata K, Hirosaka A, Techigawara M, Abe Y, Sato E, Yamaguchi N, Watanabe N, Saito T, Maehara K, Ohmoto Y, Maruyama Y. 1999. Expression of cytokine and adhesion molecule mRNA in atherectomy specimens from patients with coronary artery disease. Jpn Circ J 63:249-254.
20. Jaakkola K, Jalkanen S, Kaunismaki K, Vanttinen E, Saukko P, Alanen K, Kallajoki M, Voipio-Pulkki LM, Salmi M. 2000. Vascular adhesion protein-1, intercellular adhesion molecule-1 and P-selectin mediate leukocyte binding to ischemic heart in humans. J Am Coll Cardiol 36:122-129.
21. Jackson KA, Majka SM, Wang H, Pocius J, Hartley CJ, Majesky MW, Entman ML, Michael LH, Hirschi KK, Goodell MA. 2001. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest 107:1395-1402.
22. Kalawski R, Bugajski P, Smielecki J, Wysocki H, Olszewski R, More R, Sheridan DJ, Siminiak T. 1998. Soluble adhesion molecules in reperfusion during coronary bypass grafting. Eur J Cardiothorac Surg 14:290-295.
23. Kamihata H, Matsubara H, Nishiue T, Fujiyama S, Tsutsumi Y, Ozono R, Masaki H, Mori Y, Iba O, Tateishi E, Kosaki A, Shintani S, Murohara T, Imaizumi T, Iwasaka T. 2001. Implantation of bone marrow mononuclear cells into ischemic myocardium enhances collateral perfusion and regional function via side supply of angioblasts, angiogenic ligands, and cytokines. Circulation 104:1046-1052.
24. Kang HJ, Kim HS, Zhang SY, Park KW, Cho HJ, Koo BK, Kim YJ, Soo LD, Sohn DW, Han KS, Oh BH, Lee MM, Park YB. 2004. Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: The MAGIC cell randomised clinical trial. Lancet 363:751-756.
25. Klug MG, Soonpaa MH, Koh GY, Field LJ. 1996. Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts. J Clin Invest 98:216-224.
26. Krause DS, Theise ND, Collector MI, Henegariu O, Hwang S, Gardner R, Neutzel S, Sharkis SJ. 2001. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 105:369-377.
27. Lagasse E, Connors H, Al Dhalimy M, Reitsma M, Dohse M, Osborne L, Wang X, Finegold M, Weissman IL, Grompe M. 2000. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 6:1229-1234.
28. Lapidot T, Kollet O. 2002. The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m(null) mice. Leukemia 16:1992-2003.
29. Lee RJ, Davol PA, Sievers RE, Grabert RC, Gall JM, Yee MS, Maizel AL, Larrick JW, Lum LG. 2004. Targeting of human stem cells to myocardial infarctions in xenogeneic rat model. Presented at the Biomedical Engineering Society Annual Meeting, Philadelphia, PA, October 13-16.
30. Li RK, Jia ZQ, Weisel RD, Mickle DA, Zhang J, Mohabeer MK, Rao V, Ivanov J. 1996. Cardiomyocyte transplantation improves heart function. Ann Thorac Surg 62:654-660.
31. Lum LG, Davol PA, Sievers RE, Grabert RC, Fang Q, Gall JM, Yee MS, Larrick JW, Lee RJ. 2004a. Human stem cells armed with bispecific antibodies home to injury-specific molecules in myocardial infarcts in nude rats. Blood 104(11):736a.
32. Lum LG, Fok H, Siever R, Abedi M, Quesenberry PJ, Lee RJ. 2004b. Targeting of Lin-Sca+ hematopoietic stem cells with bispecific antibodies to injured myocardium. Blood Cells Mol Dis 32:82-87.
33. Lyn D, Liu X, Bennett NA, Emmett NL. 2000. Gene expression profile in mouse myocardium after ischemia. Physiol Genomics 2:93-100.
34. Ma XL, Weyrich AS, Lefer DJ, Buerke M, Albertine KH, Kishimoto TK, Lefer AM. 1993. Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium. Circulation 88:649-658.
35. Madeddu P, Emanueli C, Pelosi E, Salis MB, Cerio AM, Bonanno G, Patti M, Stassi G, Condorelli G, Peschle C. 2004. Transplantation of low dose CD34+KDR+ cells promotes vascular and muscular regeneration in ischemic limbs. FASEB J 18:1737-1739.
36. Mair J, Wagner I, Fridrich L, Lechleitner P, Dienstl F, Puschendorf B, Michel G. 1994. Cardiac myosin light chain-1 release in acute myocardial infarction is associated with scintigraphic estimates of myocardial scar. Clin Chim Acta 229:153-159.
37. Makino S, Fukuda K, Miyoshi S, Konishi F, Kodama H, Pan J, Sano M, Takahashi T, Hori S, Abe H, Hata J, Umezawa A, Ogawa S. 1999. Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest 103:697-705.
38. Mar JH, McNatt JM, Barasch E, Clubb FJ, Wang Y, Zholdhelyi P, Willerson JT. 1997. Improving funciton of infarcted canine myocardium by transplanting canine fetal cardiac myocytes. Circulation 96(I):556.
39. Min JY, Yang Y, Sullivan MF, Ke Q, Converso KL, Chen Y, Morgan JP, Xiao YF. 2003. Long-term improvement of cardiac function in rats after infarction by transplantation of embryonic stem cells. J Thorac Cardiovasc Surg 125:361-369.
40. Murry CE, Soonpaa MH, Reinecke H, Nakajima H, Nakajima HO, Rubart M, Pasumarthi KB, Virag JI, Bartelmez SH, Poppa V, Bradford G, Dowell JD, Williams DA, Field LJ. 2004. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature 428:664-668.
41. Nagamine H, Watanabe G, Shiobara S, Takemura H, Arai S, Tomita S. 2004. Intramyocardial CD34+ cell transplantation combined with off-pump coronary artery bypass grafting. Heart Surg Forum 7:E285-E287.
42. Nagashima M, Shin'oka T, Nollert G, Shum-Tim D, Hickey PR, Roth SJ, Kirchhoff A, Springer TA, Burke PR, Mayer JE, Jr. 1998. Effects of a monoclonal antibody to P-selectin on recovery of neonatal lamb hearts after cold cardioplegic ischemia. Circulation 98:11391-11397.
43. Nygren JM, Jovinge S, Breitbach M, Sawen P, Roll W, Hescheler J, Taneera J, Fleischmann BK, Jacobsen SE. 2004. Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. Nat Med 10:494-501.
44. Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B, Pickel J, McKay R, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. 2001a. Bone marrow cells regenerate infarcted myocardium. Nature 410:701-705.
45. Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. 2001b. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA 98:10344-10349.
46. Petersen BE, Bowen WC, Patrene KD, Mars WM, Sullivan AK, Murase N, Boggs SS, Greenberger JS, Goff JP. 1999. Bone marrow as a potential source of hepatic oval cells. Science 284:1168-1170.
47. Saito T, Kuang JQ, Bittira B, Al Khaldi A, Chiu RC. 2002. Xenotransplant cardiac chimera: Immune tolerance of adult stem cells. Ann Thorac Surg 74:19-24.
48. Scorsin M, Hagege AA, Marotte F, Mirochnik N, Copin H, Barnoux M, Sabri A, Samuel JL, Rappaport L, Menasche P. 1997. Does transplantation of cardiomyocytes improve function of infarcted myocardium? Circulation 96:11-93.
49. Sen M, Wankowski DM, Garlie NK, Siebenlist RE, Van Epps D, LeFever AV, Lum LG. 2001. Use of anti-CD3 × anti-HER2/neu bispecific antibody for redirecting cytotoxicity of activated T cells toward HER2/neu Tumors. J Hematother Stem Cell Res 10:247-260.
50. Simpson PJ, Todd RF, III, Fantone JC, Mickelson JK, Griffin JD, Lucchesi BR. 1988. Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mol, anti-CD11b) that inhibits leukocyte adhesion. J Clin Invest 81:624-629.
51. Smits PC, van Geuns RJ, Poldermans D, Bountioukos M. Underwater EE, Lee CH, Maat AP, Serruys PW. 2003. Catheter-based intramyocardial injection of autologous skeletal myoblasts as a primary treatment of ischemic heart failure: Clinical experience with six-month follow-up. J Am Coll Cardiol 42:2063-2069.
52. Stamm C, Westphal B, Kleine HD, Petzsch M, Kittner C, Klinge H, Schumichen C, Nienaber CA, Freund M, Steinhoff G. 2003. Autologous bone-marrow stem-cell transplantation for myocardial regeneration. Lancet 361:45-46.
53. Strauer BE, Brehm M, Zeus T, Kostering M, Hernandez A, Sorg RV, Kogler G, Wernet P. 2002. Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation 106:1913-1918.
54. Sun B, Fan H, Honda T, Fujimaki R, Lafond-Walker A, Masui Y, Lowenstein CJ, Becker LC. 2001. Activation of NF kappa B and expression of ICAM-1 in ischemic-reperfused canine myocardium. J Mol Cell Cardiol 33:109-119.
55. Theise ND, Badve S, Saxena R, Henegariu O, Sell S, Crawford JM, Krause DS. 2000a. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology 31:235-240.
56. Theise ND, Nimmakayalu M, Gardner R, Illei PB, Morgan G, Teperman L, Henegariu O, Krause DS. 2000b. Liver from bone marrow in humans. Hepatology 32:11-16.
57. Tomita S, Li RK, Weisel RD, Mickle DA, Kim EJ, Sakai T, Jia ZQ. 1999. Autologous transplantation of bone marrow cells improves damaged heart function. Circulation 100:11247-11256.
58. Tomita S, Ishida M, Nakatani T, Fukuhara S, Hisashi Y, Ohtsu Y, Suga M, Yutani C, Yagihara T, Yamada K, Kitamura S. 2004. Bone marrow is a source of regenerated cardiomyocytes in doxorubicin-induced cardiomyopathy and granulocyte colony-stimulating factor enhances migration of bone marrow cells and attenuates cardiotoxicity of doxorubicin under electron microscopy. J Heart Lung Transplant 23:577-584.
59. Tse HF, Kwong YL, Chan JK, Lo G, Ho CL, Lau CP. 2003. Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation. Lancet 361:47-49.
60. Wang JS, Shum-Tim D, Galipeau J, Chedrawy E, Eliopoulos N, Chiu RC. 2000. Marrow stromal cells for cellular cardiomyoplasty: Feasibility and potential clinical advantages. J Thorac Cardiovasc Surg 120:999-1005.
61. Wollert KC, Meyer GP, Lotz J, Ringes-Lichtenberg S, Lippolt P, Breidenbach C, Fichtner S, Korte T, Hornig B, Messinger D, Arseniev L, Hertenstein B, Ganser A, Drexler H. 2004. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: The BOOST randomised controlled clinical trial. Lancet 364:141-148.
62. Yang B, Li D, Phillips MI, Mehta P, Mehta JL. 1998. Myocardial angiotensin II receptor expression and ischemia-reperfusion injury. Vase Med 3:121-130.
63. Yeh ET, Zhang S, Wu HD, Korbling M, Willerson JT, Estrov Z. 2003. Transdifferentiation of human peripheral blood CD34+-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo. Circulation 108:2070-2073.
64. Young HA, Ghosh P, Ye J, Lederer J, Lichtman A, Gerard JR, Penix L, Wilson CB, Melvin AJ, McGurn ME, Lewis DB, Taub DD. 1994. Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene. J Immunol 153:3603-3610.
65. Zhang S, Wang D, Estrov Z, Raj S, Willerson JT, Yeh ET. 2004. Both cell fusion and transdifferentiation account for the transformation of human peripheral blood CD34-positive cells into cardiomyocytes in vivo. Circulation 110:3803-3807.