Activation of NFκB and expression of ICAM-1 in ischemic-reperfused canine myocardium

Journal of Molecular and Cellular Cardiology

Volumn 33, Issue 1, 2001, Pages 109-119

  Sun, Baogui ^a   Fan, Haiying ^a   Honda, Toshio ^a   Fujimaki, Rikiya ^a   Lafond Walker, Anne ^a   Masui, Yoshihiro ^a   Lowenstein, Charles J ^a   Becker, Lewis C ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

AP 1; Inflammation; NF B; Reperfusion injury; Transcription factors

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; TRANSCRIPTION FACTOR AP 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; GENE ACTIVATION; HEART MUSCLE ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; VASCULAR ENDOTHELIUM;

CANIS FAMILIARIS;

EID: 0035146094     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2000.1280     Document Type: Article

References (35)

1. Regulation of intercellular adhesion molecule-1 (ICAM-1) in ischemic and reperfused canine myocardium
2. Induction of interleukin-6 synthesis in the myocardium: Potential role in postreperfusion inflammatory injury
3. Neutrophil induced oxidative injury of cardiac myocytes: A compartmented system requiring CD11b/CD18-ICAM-1 adherence
4. Adherence of neutrophils to canine cardiac myocytes in vitro is dependent on intercellular adhesion molecule-1
5. Coronary endothelial and cardiac protective effects of a monoclonal antibody to intercellular adhesion molecule-1 in myocardial ischemia and reperfusion
6. Protection of ischemic/reperfused canine myocardium by CL18/6, a monoclonal antibody to adhesion molecule ICAM-1
7. Intercellular adhesion molecule-1-deficient mice are less susceptible to cerebral ischemia-reperfusion injury
8. Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury
9. A form of circulating ICAM-1 in human serum
10. Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells
11. 2 and tumor necrosis factor-α activate intercellular adhesion molecule 1 (ICAM-1) gene transcription through distinct cis-regulatory elements within the ICAM-1 promoter
12. Hydrogen peroxide pretreatment of perfused canine vessels induces ICAM-1 and CD18-dependent neutrophil adherence
13. Hydrogen peroxide-induced increase in endothelial adhesiveness is dependent on ICAM-1 activation
14. Oxidative stress as a regulator of gene expression in the vasculature
15. Antioxidant and redox regulation of gene transcription
16. Induction of nuclear factor κB and activation protein 1 in postischemic myocardium
17. Viscoelastic relaxation and regional blood flow response to spinal cord compression and decompression
18. Blood flow measurements with radionuclidelabelled particles
19. Enhanced expression of intercellular adhesion molecule-1 and P-selectin in the diabetic human retina and choroid
20. Transcriptional regulation of endothelial cell adhesion molecules: NF-κB and cytokine-inducible enhancers
21. Protein kinase C-activated oxidant generation in endothelial cells signals intercellular adhesion molecule-1 gene transcription
22. Protein tyrosine kinase inhibitors block tumor necrosis factor-induced activation of nuclear factor-kappaB, degradation of IkappaBalpha, nuclear translocation of p65, and subsequent gene expression
23. A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB
24. Tyrosine phosphorylation of IκB-a activates NFκB without proteolytic degradation of IκB-α
25. Inhibition of nuclear factor-κB-mediated adhesion molecule expression in human endothelial cells
26. Transcription factor decoy for nuclear factorkappaB inhibits tumor necrosis factor-alpha-induced expression of interleukin-6 and intracellular adhesion molecule-1 in endothelial cells
27. Tumor necrosis factor-α contributes to ischemia- and reperfusion-induced endothelial activation in isolated hearts
28. Hydrogen peroxide induces intracellular calcium oscillations in human aortic endothelial cells
29. Calcium oscillations increase the efficiency and specificity of gene expression
30. Neutrophil adherence to isolated adult cardiac myocytes: Induction by cardiac lymph collected during ischemia and reperfusion
31. Resident cardiac mast cells degranulate and release preformed TNF-α initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion
32. Induction of cytokine expression in leukocytes in acute myocardial infarction
33. Circulating intercellular adhesion molecule-1 and E-selectin in patients with acute coronary syndrome
34. Soluble forms of E-selectin, ICAM-1 and VCAM-1 are present in the supernatants of cytokine activated cultured endothelial cells
35. The native structure of intercellular adhesion molecule-1 (ICAM-1) is a dimer. Correlation with binding to LFA-1