Targeting of Lin-Sca+ hematopoietic stem cells with bispecific antibodies to injured myocardium

Blood Cells, Molecules, and Diseases

Volumn 32, Issue 1, 2004, Pages 82-87

  Lum, Lawrence G ^a,e   Fok, Hubert ^b,c   Sievers, Richard ^b,c   Abedi, Mehrdad ^d,e   Quesenberry, Peter J ^d,e   Lee, Randall J ^b,c  

^a Adele R Decof Cancer Center   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d ROGER WILLIAMS MEDICAL CENTER   (United States)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bispecific antibodies; Lin Sca+ cells; Myocardial infarction

Indexed keywords

BISPECIFIC ANTIBODY; FLUORESCENT DYE; PROTEIN ANTIBODY; STEM CELL FACTOR; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EXPERIMENTAL MOUSE; HEART DEATH; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE INJURY; HEMATOPOIETIC STEM CELL; INTERNAL JUGULAR VEIN; LEFT ANTERIOR DESCENDING CORONARY ARTERY; LIGATION; LIN SCA POSITIVE HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REJUVENATION; STEM CELL; T LYMPHOCYTE; TARGET CELL; TISSUE REGENERATION; TISSUE REPAIR; UPREGULATION;

MURINAE;

EID: 0742289570     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2003.09.019     Document Type: Article

References (16)

1. Lenfant C. Fixing the failing heart. Circulation. 95:1997;771-772.
2. American Heart Association Heart and Stroke Statistical Update. 2001;American Heart Association, Dallas, TX.
3. Lenfant C. Cardiovascular research: an NIH perspective. Cardiovasc. Surg. 5:1997;4-5.
4. Cohn J.N., Bristow M.R., Chien K.R., Colucci W.S., Frazier O.H., Leinwand L.A., Lorell B.H., Moss A.J., Sonnenblick E.H., Walsh R.A., Mockrin S.C., Reinlib L. Report of the National Heart, Lung, and Blood Institute special emphasis panel on heart failure research. Circulation. 95:1997;766-770.
5. Orlic D., Kajstura J., Chimenti S., Jakoniuk I., Anderson S.M., Li B., Pickel J., McKay R., Nadal-Ginard B., Bodine D.M., Leri A., Anversa P. Bone marrow cells regenerate infarcted myocardium. Nature. 410:2001;701-705.
6. Perin E.C., Dohmann H.F., Borojevic R., Silva S.A., Sousa A.L., Mesquita C.T., Rossi M.I., Carvalho A.C., Dutra H.S., Dohmann H.J., Silva G.V., Belem L., Vivacqua R., Rangel F.O., Esporcatte R., Geng Y.J., Vaughn W.K., Assad J.A., Mesquita E.T., Willerson J.T. Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure. Circulation. 107:2003;2294-2302.
7. Sen M., Wankowski D.M., Garlie N.K., Siebenlist R.E., Van Epps D., LeFever A.V., Lum L.G. Use of anti-CD3 × anti-HER2/neu bispecific antibody for redirecting cytotoxicity of activated T cells toward HER2/neu Tumors. J. Hematother. Stem Cell Res. 10:2001;247-260.
8. Smith J.A., Davol P.A., Kouttab N., Rathore R., Elfenbein G.J., Lum L.G. Activated T cells armed with Anti-CD3 × Anti-HER2/neu bispecific antibody I: anti-tumor activity and survival in SCID/Beige mice. Blood. 100(11):2002 (November 16);673a.
9. Grabert R.C., Smith J., Tiggs J., Kouttab N., Lum L. Anti-CD3 activated T cells armed with OKT3 × herceptin bispecific antibody, survive and divide, and secrete cytokines and chemokines after multiple cycles of killing directed at Her2/neu+ tumor targets. Proc. Am. Assoc. Cancer Res. 44:2003;656.
10. Sun B., Fan H., Honda T., Fujimaki R., Lafond-Walker A., Masui Y., Lowenstein C.J., Becker L.C. Activation of NF kappa B and expression of ICAM-1 in ischemic- reperfused canine myocardium. J. Mol. Cell Cardiol. 33:2001;109-119.
11. Hartman J.C., Anderson D.C., Wiltse A.L., Lane C.L., Rosenbloom C.L., Manning A.M., Humphrey W.R., Wall T.M., Shebuski R.J. Protection of ischemic/reperfused canine myocardium by CL18/6, a monoclonal antibody to adhesion molecule ICAM-1. Cardiovasc. Res. 30:1995;47-54.
12. Jaakkola K., Jalkanen S., Kaunismaki K., Vanttinen E., Saukko P., Alanen K., Kallajoki M., Voipio-Pulkki L.M., Salmi M. Vascular adhesion protein-1, intercellular adhesion molecule-1 and P-selectin mediate leukocyte binding to ischemic heart in humans. J. Am. Coll. Cardiol. 36:2000;122-129.
13. Ma X.L., Weyrich A.S., Lefer D.J., Buerke M., Albertine K.H., Kishimoto T.K., Lefer A.M. Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium. Circulation. 88:1993;649-658.
14. Cerny J., Dooner M., McAuliffe C., Habibian H., Stencil K., Berrios V., Reilly J., Carlson J., Cerny A.M., D'Hondt L., Benoit B., Lambert J.F., Colvin G., Nilsson S., Becker P., Quesenberry P. Homing of purified murine lymphohematopoietic stem cells: a cytokine-induced defect. J. Hematother. Stem Cell Res. 11:2002;913-922.
15. Orlic D. Hematopoietic cells regenerate infarcted myocardium. Exp. Hematol. 2001;4. (supplement).
16. Orlic D., Kajstura J., Chimenti S., Li B., Anderson S.M., Jakoniuk I., Pickel J., McKay R., Bodine D.M., Leri A., Anversa P. Transplanted hematopoietic stem cells repair myocardial infarcts. Blood. 96(11):2001;221a.