Neurotrophic activities of trk receptors conserved over 600 million years of evolution

Journal of Neurobiology

Volumn 60, Issue 1, 2004, Pages 12-20

  Beck, Gad ^a   Munno, David W ^b   Levy, Zehava ^a   Dissel, Helga M ^c   Van Minnen, Jan ^c   Syed, Naweed I ^b   Fainzilber, Mike ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF CALGARY   (Canada)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Evolution; Neuronal survival; Neurotrophin; NGF; trk; Trophic

Indexed keywords

IMMUNOGLOBULIN; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; NEUROTROPHIC FACTOR; NEUROTROPHIN; PROTEIN TYROSINE KINASE; TRK RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; EVOLUTION; EXON; GENE EXPRESSION; GENETIC CONSERVATION; GENETIC TRANSFECTION; INTRON; INVERTEBRATE; LYMNAEA; MOLLUSC; MULTIGENE FAMILY; NERVE CELL; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; VERTEBRATE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; EVOLUTION; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LYMNAEA; MOLECULAR SEQUENCE DATA; NEURONS; POLYMERASE CHAIN REACTION; PROTEIN STRUCTURE, QUATERNARY; RECEPTOR, TRKA; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY;

EID: 2642568028     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/neu.10329     Document Type: Article

References (46)

1. Abrams JM, White K, Fessler LI, Steller H. 1993. Programmed cell death during Drosophila embryogenesis. Development 117:29-43.
2. Acheson A, Conover JC, Fandl JP, DeChiara TM, Russell M, Thadani A, Squinto SP, Yancopoulos GD, Lindsay RM. 1995. A BDNF autocrine loop in adult sensory neurons prevents cell death. Nature 374:450-453.
3. Barde YA. 1994. Neurotrophic factors: an evolutionary perspective. J Neurobiol 25:1329-1333.
4. Beck G, Fainzilber M. 2002. Genetic models meet trophic mechanisms: EGF family members are gliatrophins in Drosophila. Neuron 33:673-675.
5. Bergmann A, Tugentman M, Shilo BZ, Steller H. 2002. Regulation of cell number by MAPK-dependent control of apoptosis: a mechanism for trophic survival signaling. Dev Cell 2:1-20.
6. Bogerd J, Van Kesteren RE, Van Heerikhuizen H, Geraerts WP, Veenstra J, Smit AB, Joosse J. 1993. Alternative splicing generates diversity of VD1/RPD2 alpha peptides in the central nervous system of Lymnaea stagnalis. Cell Mol Neurobiol 13:123-136.
7. Chao MV. 2000. Trophic factors: an evolutionary cul-desac or door into higher neuronal function? J Neurosci Res 59:353-355.
8. Chisholm A, Tessier-Lavigne M. 1999. Conservation and divergence of axon guidance mechanisms. Curr Opin Neurobiol 9:603-615.
9. Croll RP. 2000. Insights into early molluscan neuronal development through studies of transmitter phenotypes in embryonic pond snails. Microsc Res Tech 49:570-578.
10. Esposito D, Patel P, Stephens RM, Perez P, Chao MV, Kaplan DR, Hempstead BL. 2001. The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor. J Biol Chem 276:32687-32695.
11. Fainzilber M, Smit AB, Syed NI, Wildering WC, Hermann PM, van der Schors RC, Jimenez C, Li KW, van-Minnen MJ, Bulloch AG, Ibanez CF, Geraerts WP. 1996. CRNF, a molluscan neurotrophic factor that interacts with the p75 neurotrophin receptor. Science 274:1540-1543.
12. Ginty DD, Segal RA. 2002. Retrograde neurotrophin signaling: Trk-ing along the axon. Curr Opin Neurobiol 12:268-274.
13. Gough J, Karplus K, Hughey R, Chothia C. 2001. Assignment of homology to genome sequences using a library of hidden Markov models that represent all proteins of known structure. J Mol Biol 313:903-919.
14. Hallbook F. 1999. Evolution of the vertebrate neurotrophin and Trk receptor gene families. Curr Opin Neurobiol 9:616-621.
15. Hamakawa T, Woodin MA, Bjorgum MC, Painter SD, Takasaki M, Lukowiak K, Nagle GT, Syed NI. 1999. Excitatory synaptogenesis between identified Lymnaea neurons requires extrinsic trophic factors and is mediated by receptor tyrosine kinases. J Neurosci 19:9306-9312.
16. Hermann PM, van Kesteren RE, Wildering WC, Painter SD, Reno JM, Smith JS, Kumar SB, Geraerts WP, Ericsson LH, Smit AB, Bulloch AG, Nagle GT. 2000. Neurotrophic actions of a novel molluscan epidermal growth factor. J Neurosci 20:6355-6364.
17. Hidalgo A. 2002. Interactive nervous system development: control of cell survival in Drosophila. Trends Neurosci 25:365-370.
18. Hidalgo A, Kinrade EF, Georgiou M. 2001. The Drosophila neuregulin vein maintains glial survival during axon guidance in the CNS. Dev Cell 1:679-690.
19. Huang EJ, Reichardt LF. 2001. Neurotrophins: roles in neuronal development and function. Annu Rev Neurosci 24:677-736.
20. Jaaro H, Beck G, Conticello SG, Fainzilber M. 2001. Evolving better brains: a need for neurotrophins? Trends Neurosci 24:79-85.
21. Kelley LA, MacCallum RM, Sternberg MJ. 2000. Enhanced genome annotation using structural profiles in the program 3D-PSSM. J Mol Biol 299:499-520.
22. Korneev SA, Kemenes I, Straub V, Staras K, Korneeva EI, Kemenes G, Benjamin PR, O'Shea M. 2002. Suppression of nitric oxide (NO)-dependent behavior by double-stranded RNA-mediated silencing of a neuronal NO synthase gene. J Neurosci 22:RC227.
23. Lim CS, Lee JC, Kim SD, Chang DJ, Kaang BK. 2002. Hydrogen peroxide-induced cell death in cultured Aplysia sensory neurons. Brain Res 941:137-145.
24. Liu J, Tzou P, Hill RJ, Sternberg PW. 1999. Structural requirements for the tissue-specific and tissue-general functions of the Caenorhabditis elegans epidermal growth factor LIN-3. Genetics 153:1257-1269.
25. Miller MA, Steele RE. 2000. Lemon encodes an unusual receptor protein-tyrosine kinase expressed during gametogenesis in Hydra. Dev Biol 224:286-298.
26. Moreno H, Nadal M, Leznik E, Sugimori M, Lax I, Schlessinger J, Llinas R. 1998. Nerve growth factor acutely reduces chemical transmission by means of postsynaptic TrkA-like receptors in squid giant synapse. Proc Natl Acad Sci USA 95:14997-15002.
27. Munno DW, Woodin MA, Lukowiak K, Syed NI, Dickinson PS. 2000. Different extrinsic trophic factors regulate neurite outgrowth and synapse formation between identified Lymnaea neurons. J Neurobiol 44:20-30.
28. Ninkina N, Grashchuck M, Buchman VL, Davies AM. 1997. TrkB variants with deletions in the leucine-rich motifs of the extracellular domain. J Biol Chem 272: 13019-13025.
29. Pertea M, Lin X, Salzberg SL. 2001. GeneSplicer: a new computational method for splice site prediction. Nucleic Acids Res 29:1185-1190.
30. Pulido D, Campuzano S, Koda T, Modolell J, Barbacid M. 1992. Dtrk, a Drosophila gene related to the trk family of neurotrophin receptors, encodes a novel class of neural cell adhesion molecule. EMBO J 11:391-404.
31. Ridgway R, Syed NI, Lukowiak K, Bulloch AG. 1991. Nerve growth factor (NGF) induces sprouting of specific neurons of the snail, Lymnaea stagnalis. J Neurobiol 22:377-390.
32. Roovers E, Vincent ME, van Kesteren E, Geraerts WP, Planta RJ, Vreugdenhil E, van Heerikhuizen H. 1995. Characterization of a putative molluscan insulin-related peptide receptor. Gene 162:181-188.
33. Rost B, Sander C. 2000. Third generation prediction of secondary structures. Methods Mol Biol 143:71-95.
34. Smit AB, Syed NI, Schaap D, van Minnen J, Klumperman J, Kits KS, Lodder H, van der Schors RC, van Elk R, Sorgedrager B, Brejc K, Sixma TK, Geraerts WP. 2001. A glia-derived acetylcholine-binding protein that modulates synaptic transmission. Nature 411:261-268.
35. Stoilov P, Castren E, Stamm S. 2002. Analysis of the human TrkB gene genomic organization reveals novel TrkB isoforms, unusual gene length, and splicing mechanism. Biochem Biophys Res Commun 290:1054-1065.
36. Syed N, Richardson P, Bulloch A. 1996. Ciliary neurotrophic factor, unlike nerve growth factor, supports neurite outgrowth but not synapse formation by adult Lymnaea neurons. J Neurobiol 29:293-303.
37. Syed NI, Bulloch AG, Lukowiak K. 1990. In vitro reconstruction of the respiratory central pattern generator of the mollusk Lymnaea. Science 250:282-285.
38. Thompson LM, Raffioni S, Wasmuth JJ, Bradshaw RA. 1997. Chimeras of the native form or achondroplasia mutant (G375C) of human fibroblast growth factor receptor 3 induce ligand-dependent differentiation of PC12 cells. Mol Cell Biol 17:4169-4177.
39. van Kesteren RE, Fainzilber M, Hauser G, van Minnen J, Vreugdenhil E, Smit AB, Ibanez CF, Geraerts WP, Bulloch AG. 1998. Early evolutionary origin of the neurotrophin receptor family. EMBO J 17:2534-2542.
40. Werner S, Duan DS, de Vries C, Peters KG, Johnson DE, Williams LT. 1992. Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities. Mol Cell Biol 12:82-88.
41. Wiesmann C, de Vos AM. 2001. Nerve growth factor: structure and function. Cell Mol Life Sci 58:748-759.
42. Wiesmann C, Ultsch MH, Bass SH, de Vos AM. 1999. Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor. Nature 401:184-188.
43. Winberg ML, Tamagnone L, Bai J, Comoglio PM, Montell D, Goodman CS. 2001. The transmembrane protein off-track associates with plexins and functions downstream of semaphorin signaling during axon guidance. Neuron 32:53-62.
44. Windisch JM, Marksteiner R, Lang ME, Auer B, Schneider R. 1995. Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 bind to a single leucine-rich motif of TrkB. Biochemistry 34:11256-11263.
45. Zaccaro MC, Ivanisevic L, Perez P, Meakin SO, Saragovi HU. 2001. p75 co-receptors regulate ligand-dependent and ligand-independent Trk receptor activation, in part by altering Trk docking subdomains. J Biol Chem 276:31023-31029.
46. Zhang Y, Moheban DB, Conway BR, Bhattacharyya A, Segal RA. 2000. Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation. J Neurosci 20:5671-5678.