The transmembrane protein off-track associates with plexins and functions downstream of semaphorin signaling during axon guidance

Neuron

Volumn 32, Issue 1, 2001, Pages 53-62

  Winberg, Margaret ^a   Tamagnone, Luca ^b   Bai, Jianwu ^c   Comoglio, Paolo ^b   Montell, Denise ^c   Goodman, Corey S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TURIN   (Italy)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; MEMBRANE PROTEIN; PLEXIN A RECEPTOR; PROTEIN OFF TRACK; RECEPTOR; SEMAPHORIN; SEMAPHORIN SEMA 1A; UNCLASSIFIED DRUG;

ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; DROSOPHILA; EMBRYO; GENE MUTATION; GENETIC ANALYSIS; NERVE FIBER; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0034782822     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(01)00446-9     Document Type: Article

References (40)

1. Notch signaling
2. Chimeric axon guidance receptors: The cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion
3. Axon routing across the midline controlled by the Drosophila Derailed receptor
4. Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance
5. Signaling by Eph receptors and their ephrin ligands
6. Control of neuronal pathway selection by a Drosophila receptor protein-tyrosine kinase family member
7. Characterization of a member of the immunoglobulin gene superfamily that possibly represents an additional class of growth factor receptor
8. A poxvirus-encoded semaphorin induces cytokine production from monocytes and binds to a novel cellular semaphorin receptor, VESPR
9. Plexin-B semaphorin receptors interact directly with active Rac and regulate the actin cytoskeleton by activating Rho
10. Ephrins and their Eph receptors: Multitalented directors of embryonic development
11. Plexin B mediates axon guidance in Drosophila by simultaneously inhibiting active Rac and enhancing RhoA signaling
12. Functional analysis of H-Ryk, an atypical member of the receptor tyrosine kinase family
13. Deleted in colorectal cancer (DCC) encodes a netrin receptor
14. Slit is the midline repellent for the robo receptor in Drosophila
15. A neural tetraspanin, encoded by late bloomer, that facilitates synapse formation
16. Deceiving appearances: Signaling by "dead" and "fractured" receptor protein-tyrosine kinases
17. Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors
18. UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans
19. Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons
20. Ectopic and increased expression of Fasciclin II alters motoneuron growth cone guidance
21. Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion
22. A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor
23. Colon carcinoma kinase-4 defines a new subclass of the receptor tyrosine kinase family
24. Plexin: A novel neuronal cell surface molecule that mediates cell adhesion via a homophilic binding mechanism in the presence of calcium ions
25. Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG
26. Dtrk, a Drosophila gene related to the trk family of neurotrophin receptors, encodes a novel class of neural cell adhesion molecule
27. The semaphorin 3A receptor may directly regulate the activity of small GTPases
28. A modular misexpression screen in Drosophila detecting tissue-specific phenotypes
29. Intermittent divergence of the protein tyrosine kinase family during animal evolution
30. Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors
31. Signalling by semaphorin receptors: Cell guidance and beyond
32. Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates
33. The molecular biology of axon guidance
34. Early evolutionary origin of the neurotrophin receptor family
35. Genes that control neuromuscular specificity in Drosophila
36. The semaphorin receptor plexin-B1 specifically interacts with active Rac in a ligand-dependent manner
37. Frequent imprecise excision among reversions of a P element-caused lethal mutation in Drosophila
38. Plexin A is a neuronal semaphorin receptor that controls axon guidance
39. The transmembrane Semaphorin Sema I is required in Drosophila for embryonic motor and CNS axon guidance
40. Determination of neuronal cell fate: Lessons from the R7 neuron of Drosophila