Activation of purified allogeneic CD4+ T cells by rat bone marrow-derived dendritic cells induces concurrent secretion of IFN-γ, IL-4, and IL-10

Immunology Letters

Volumn 101, Issue 2, 2005, Pages 193-201

  Janelidze, Shorena ^a   Enell, Karin ^a   Visse, Edward ^a   Darabi, Anna ^a   Salford, Leif G ^a   Siesjö, Peter ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Bone marrow; Dendritic cells; Endocytosis; MLR; TH1 TH2 polarization

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; FLT3 LIGAND; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ALLOGENIC BONE MARROW TRANSPLANTATION; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL CULTURE; CELL MATURATION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; ENDOCYTOSIS; HELPER CELL; IMMUNOREGULATION; INTERNALIZATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MIXED LYMPHOCYTE REACTION; NONHUMAN; PHAGOCYTOSIS; POLARIZATION; PRIORITY JOURNAL; PURIFICATION; RAT; T LYMPHOCYTE ACTIVATION; UPREGULATION;

ANIMALS; BONE MARROW CELLS; CD4-POSITIVE T-LYMPHOCYTES; CELL POLARITY; CELL PROLIFERATION; CELL SEPARATION; CELLS, CULTURED; DENDRITIC CELLS; DOWN-REGULATION; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-4; MALE; PHENOTYPE; RATS; TH1 CELLS; TH2 CELLS;

EID: 25444507413     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2005.05.012     Document Type: Article

References (47)

1. F.P. Huang, N. Platt, M. Wykes, J.R. Major, T.J. Powell, and C.D. Jenkins A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes J Exp Med 191 2000 435 444
2. D. Hawiger, K. Inaba, Y. Dorsett, M. Guo, K. Mahnke, and M. Rivera Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo J Exp Med 194 2001 769 779
3. L. Bonifaz, D. Bonnyay, K. Mahnke, M. Rivera, M.C. Nussenzweig, and R.M. Steinman Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance J Exp Med 196 2002 1627 1638
4. R. Maldonado-Lopez, T. De Smedt, P. Michel, J. Godfroid, B. Pajak, and C. Heirman CD8alpha+ and CD8alpha- subclasses of dendritic cells direct the development of distinct T helper cells in vivo J Exp Med 189 1999 587 592
5. B. Pulendran, J.L. Smith, G. Caspary, K. Brasel, D. Pettit, and E. Maraskovsky Distinct dendritic cell subsets differentially regulate the class of immune response in vivo Proc Natl Acad Sci USA 96 1999 1036 1041
6. M.C. Rissoan, V. Soumelis, N. Kadowaki, G. Grouard, F. Briere, and R. de Waal Malefyt Reciprocal control of T helper cell and dendritic cell differentiation Science 283 1999 1183 1186
7. M. Moser, and K.M. Murphy Dendritic cell regulation of TH1-TH2 development Nat Immunol 1 2000 199 205
8. F. Sallusto, and A. Lanzavecchia Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/ macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha J Exp Med 179 1994 1109 1118
9. N. Romani, S. Gruner, D. Brang, E. Kampgen, A. Lenz, and B. Trockenbacher Proliferating dendritic cell progenitors in human blood J Exp Med 180 1994 83 93
10. R. Agger, M.S. Petersen, H.E. Toldbod, S. Holtz, F. Dagnaes-Hansen, and B.W. Johnsen Characterization of murine dendritic cells derived from adherent blood mononuclear cells in vitro Scand J Immunol 52 2000 138 147
11. C. Caux, C. Dezutter-Dambuyant, D. Schmitt, and J. Banchereau GM-CSF and TNF-alpha cooperate in the generation of dendritic Langerhans cells Nature 360 1992 258 261
12. K. Inaba, M. Inaba, N. Romani, H. Aya, M. Deguchi, and S. Ikehara Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor J Exp Med 176 1992 1693 1702
13. S. Siena, M. Di Nicola, M. Bregni, R. Mortarini, A. Anichini, and L. Lombardi Massive ex vivo generation of functional dendritic cells from mobilized CD34+ blood progenitors for anticancer therapy Exp Hematol 23 1995 1463 1471
14. P. Szabolcs, M.A. Moore, and J.W. Young Expansion of immunostimulatory dendritic cells among the myeloid progeny of human CD34+ bone marrow precursors cultured with c-kit ligand, granulocyte-macrophage colony-stimulating factor, and TNF-alpha J Immunol 154 1995 5851 5861
15. M.B. Lutz, N. Kukutsch, A.L. Ogilvie, S. Rossner, F. Koch, and N. Romani An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow J Immunol Methods 223 1999 77 92
16. M. Chen-Woan, C.P. Delaney, V. Fournier, Y. Wakizaka, N. Murase, and J. Fung A new protocol for the propagation of dendritic cells from rat bone marrow using recombinant GM-CSF, and their quantification using the mAb OX-62 J Immunol Methods 178 1995 157 171
17. M. Mehlig, C. Scheicher, H.P. Dienes, and K. Reske Development of rat DC by in vitro culture of bone marrow cells Adv Exp Med Biol 378 1995 71 73
18. M. Talmor, A. Mirza, S. Turley, I. Mellman, L.A. Hoffman, and R.M. Steinman Generation or large numbers of immature and mature dendritic cells from rat bone marrow cultures Eur J Immunol 28 1998 811 817
19. C.S. Brissette-Storkus, J.C. Kettel, T.F. Whitham, K.M. Giezeman-Smits, L.A. Villa, and D.M. Potter Flt-3 ligand (FL) drives differentiation of rat bone marrow-derived dendritic cells expressing OX62 and/or CD161 (NKR-P1) J Leukoc Biol 71 2002 941 949
20. O. Grauer, G. Wohlleben, S. Seubert, A. Weishaupt, E. Kampgen, and R. Gold Analysis of maturation states of rat bone marrow-derived dendritic cells using an improved culture technique Histochem Cell Biol 117 2002 351 362
21. A. Curti, M. Fogli, M. Ratta, S. Tura, and R.M. Lemoli Stem cell factor and FLT3-ligand are strictly required to sustain the long-term expansion of primitive CD34+ DR-dendritic cell precursors J Immunol 166 2001 848 854
22. E. Maraskovsky, K. Brasel, M. Teepe, E.R. Roux, S.D. Lyman, and K. Shortman Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified J Exp Med 184 1996 1953 1962
23. E. Daro, B. Pulendran, K. Brasel, M. Teepe, D. Pettit, and D.H. Lynch Polyethylene glycol-modified GM-CSF expands CD11b(high) CD11c(high) but notCD11b(low) CD11c(high) murine dendritic cells in vivo: a comparative analysis with Flt3 ligand J Immunol 165 2000 49 58
24. E. Maraskovsky, E. Daro, E. Roux, M. Teepe, C.R. Maliszewski, and J. Hoek In vivo generation of human dendritic cell subsets by Flt3 ligand Blood 96 2000 878 884
25. B. Blom, S. Ho, S. Antonenko, and Y.J. Liu Generation of interferon alpha-producing predendritic cell (pre-DC)2 from human CD34(+) hematopoietic stem cells J Exp Med 192 2000 1785 1796
26. B. Pulendran, J. Banchereau, S. Burkeholder, E. Kraus, E. Guinet, and C. Chalouni Flt3-ligand and granulocyte colony-stimulating factor mobilize distinct human dendritic cell subsets in vivo J Immunol 165 2000 566 572
27. C. Asselin-Paturel, A. Boonstra, M. Dalod, I. Durand, N. Yessaad, and C. Dezutter-Dambuyant Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology Nat Immunol 2 2001 1144 1150
28. P. Bjorck Isolation and characterization of plasmacytoid dendritic cells from Flt3 ligand and granulocyte-macrophage colony-stimulating factor-treated mice Blood 98 2001 3520 3526
29. H. Nakano, M. Yanagita, and M.D. Gunn CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells J Exp Med 194 2001 1171 1178
30. M. Gilliet, A. Boonstra, C. Paturel, S. Antonenko, X.L. Xu, and G. Trinchieri The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor J Exp Med 195 2002 953 958
31. R.M. Steinman, and J. Swanson The endocytic activity of dendritic cells J Exp Med 182 1995 283 288
32. F. Sallusto, M. Cella, C. Danieli, and A. Lanzavecchia Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products J Exp Med 182 1995 389 400
33. T.J. Powell, C.D. Jenkins, R. Hattori, and G.G. MacPherson Rat bone marrow-derived dendritic cells, but not ex vivo dendritic cells, secrete nitric oxide and can inhibit T-cell proliferation Immunology 109 2003 197 208
34. L. Liu, M. Zhang, C. Jenkins, and G.G. MacPherson Dendritic cell heterogeneity in vivo: two functionally different dendritic cell populations in rat intestinal lymph can be distinguished by CD4 expression J Immunol 161 1998 1146 1155
35. B. Trinite, C. Voisine, H. Yagita, and R. Josien A subset of cytolytic dendritic cells in rat J Immunol 165 2000 4202 4208
36. M. de la Mata, C.M. Riera, and P. Iribarren Identification of a CD8alpha(+) dendritic cell subpopulation in rat spleen and evaluation of its OX-62 expression Clin Immunol 101 2001 371 378
37. E. Turnbull, and G. MacPherson Immunobiology of dendritic cells in the rat Immunol Rev 184 2001 58 68
38. C. Voisine, F.X. Hubert, B. Trinite, M. Heslan, and R. Josien Two phenotypically distinct subsets of spleen dendritic cells in rats exhibit different cytokine production and T cell stimulatory activity J Immunol 169 2002 2284 2291
39. P.A. Stumbles, J.A. Thomas, C.L. Pimm, P.T. Lee, T.J. Venaille, and S. Proksch Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity J Exp Med 188 1998 2019 2031
40. D.F. Fiorentino, M.W. Bond, and T.R. Mosmann Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones J Exp Med 170 1989 2081 2095
41. H. Yssel, R. De Waal Malefyt, M.G. Roncarolo, J.S. Abrams, R. Lahesmaa, and H. Spits IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells J Immunol 149 1992 2378 2384
42. M. Cella, F. Facchetti, A. Lanzavecchia, and M. Colonna Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization Nat Immunol 1 2000 305 310
43. N. Kadowaki, S. Antonenko, J.Y. Lau, and Y.J. Liu Natural interferon alpha/beta-producing cells link innate and adaptive immunity J Exp Med 192 2000 219 226
44. H. Groux, A. O'Garra, M. Bigler, M. Rouleau, S. Antonenko, and J.E. de Vries A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis Nature 389 1997 737 742
45. F.J. Barrat, D.J. Cua, A. Boonstra, D.F. Richards, C. Crain, and H.F. Savelkoul In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines J Exp Med 195 2002 603 616
46. M.B. Lutz, and G. Schuler Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol 23 2002 445 449
47. H. Jonuleit, E. Schmitt, G. Schuler, J. Knop, and A.H. Enk Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells J Exp Med 192 2000 1213 1222