Induction of thymidine phosphorylase by interferon and taxanes occurs only in human cancer cells with low thymidine phosphorylase activity

Cancer Letters

Volumn 187, Issue 1-2, 2002, Pages 103-110

  Fukushima, Masakazu ^a   Okabe, Hiroyuki ^a   Takechi, Teiji ^a   Ichikawa, Wataru ^b   Hirayama, Renzo ^b  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Interferon; Paclitaxel; STAT1 ; Thymidine phosphorylase; Transcriptional factor; Up regulation; Uridine phosphorylase

Indexed keywords

ALPHA INTERFERON; INTERFERON; MESSENGER RNA; PACLITAXEL; STAT1 PROTEIN; TAXANE DERIVATIVE; THYMIDINE PHOSPHORYLASE; TRANSCRIPTION FACTOR; URIDINE PHOSPHORYLASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER SURGERY; CARCINOMA; CELL STRAIN KB; COLORECTAL CARCINOMA; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INDUCTION; FEMALE; GENE AMPLIFICATION; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NUDE MOUSE; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH CARCINOMA; TRANSCRIPTION REGULATION; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DNA PRIMERS; ENZYME INDUCTION; HUMANS; INTERFERON ALFA-2A; INTERFERON-STIMULATED GENE FACTOR 3; MICE; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; PACLITAXEL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THYMIDINE PHOSPHORYLASE; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; UP-REGULATION; URIDINE PHOSPHORYLASE;

MUS MUSCULUS;

EID: 0037058626     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(02)00358-0     Document Type: Article

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