Commercial plant breeding: What is in the biotech pipeline?

Journal of Commercial Biotechnology

Volumn 10, Issue 3, 2004, Pages 209-223

  Cockburn, Andrew ^a  

^a Monsanto UK Ltd   (United Kingdom)

Author keywords

Climate change; Genetic modification; Land resources; Population increase; Water shortage

Indexed keywords

BIOFUEL; PLANT MEDICINAL PRODUCT; PLASTIC; WATER;

AGRICULTURE; ANIMAL HEALTH; BIODIVERSITY; CLIMATE CHANGE; COMMERCIAL PHENOMENA; ENVIRONMENTAL PROTECTION; FIBER; FOOD BIOTECHNOLOGY; FOOD INDUSTRY; FOREST; GENOMICS; INTERNATIONAL COOPERATION; LAND USE; LIVESTOCK; NONHUMAN; PLANT BREEDING; POLITICS; POPULATION GROWTH; PREDICTION; PRODUCTIVITY; REVIEW; SUSTAINABLE AGRICULTURE;

ANIMALIA;

EID: 2542471458     PISSN: 14628732     EISSN: None     Source Type: Journal    
DOI: 10.1057/palgrave.jcb.3040076     Document Type: Review

References (102)

1. UNEP (2002), 'Synthesis GEO-3. Global Environmental Outlook 3; past, present and future perspectives' (URL: http:// www.grida.no/geo/geo3/english/overview/ 001.htm).
2. FAOSTAT (2003), Food and Agriculture Organisation (FAO) agricultural database (URL:http://apps.fao.org/page/ collections?subset=agriculture).
3. UNDP (2001), 'Human Development Report 2001. Making New Technologies Work for Human Development', Oxford University Press Inc., New York (http:// hdr.undp.org/reports/global/2001/en/).
4. Pinstrup-Andersen, P., Pandya-Loch, R. and Rosegrant, M. W. (1999), 'World Food Projects, Critical Issues for the Early 21st Century', 2020 Food Policy Report, International Food Policy Research Institute, Washington, DC.
5. Oerke, E. C. (2002), 'Crop losses due to pest in major crops', in 'CAB International Crop Protection Compendium 2002. Economic impact', CAB International, Wallingford.
6. UNDP (2001), 'Partnerships to fight poverty', Annual Report 2001, United Nations Development Programme, New York.
7. IFPRI (2002), 'Reaching Sustainable Food Security for All by 2020: Getting the Priorities and Responsibilities Right', slideshow presentation, International Food Policy Research Institute, Washington, DC (URL: www.ifpri.org/2020/books/ actionppt/actionppt.pdf).
8. WHO (1999), 'Making a difference', World Health Report 1999, WHO (URL: http:// www.who.int/whr2001/2001/archives/ 1999/en/).
9. Rosegrant, M. W, Cai, X. and Cline, S. A. (2002), 'Global Water Outlook to 2025: Averting an impending crisis', IFPRI, Washington, DC.
10. Pew (2003), URL: http:// www.pewclimate.org/global-warming-in-depth/ environmental_impacts/
11. Heap, B. (2003), 'GM crops and the Third World', in Ford, B. J., Ed, 'GM Crops, the Scientists Speak', Rothay House, Cambridge, pp. 79-87.
12. Berry, C. (2003), 'Before Frankenstein', Quart. J. Med., Vol. 96, pp. 779-780.
13. Harlander, S. H. (2002), 'The evolution of modern agriculture and its future with biotechnology', J. Amer. Coll. Nutr., Vol. 21(3), pp. 161-165.
14. Oerke, E. C. and Dehne, H. W. (1997), 'Global crop production and the efficacy of crop protection. Current situation and future trends', Europ. J. Plant Pathol., Vol. 103, pp. 203-215.
15. Pimentel, D. (2001), 'Pricing biodiversity and ecosystem services', Bioscience, Vol. 51, pp. 270-271.
16. Pretty, J. (2003), 'Could GM Crops Bring Benefits for Developing Countries?', Briefing Note for the GM Science Review Panel.
17. Prakash, C. S. (2001). 'The genetically modified crop debate in the context of agricultural evolution', Plant Physiol., Vol. 126, pp. 8-15.
18. Reiss, M. J. and Straughan, R. (2002), 'Improving Nature? The Science and Ethics of Genetic Engineering', Cambridge University Press, Cambridge.
19. James, C. (2002), 'Global Status of Commercialization Transgenic Crops: 2002', ISAAA briefs no. 27-2002 (URL: http:// www.isaaa.org/).
20. Nuffield Council on Bioethics (2003), 'The use of genetically modified crops in developing countries. A follow-up Discussion Paper to the 1999 Report "Genetically modified crops: the ethical and social issues", Nuffield Council of Bioethics, London (URL: http://www.nuffieldbioethics.org).
21. ESTO (2003), 'Review of GMOs under research and development and in the pipeline in Europe prepared by Karine Lheureux, Monique Libeau-Dulos, Hans Nilsagard, Emilio Rodrigues Cerezo (JRC - IPTS, EC), Klaus Menrad, Martina Menrad (Fraunhofer ISI, Germany), Daniel Vorgrimler (University of Stuttgard-Hohenheim)', European Science and Technology Observatory Joint Research Centre, European Commission (URL: http://esto.irc.es/ detailshort.cfm?ID_report=1091).
22. Betz, F., Hammond, B. and Fuchs, R. (2000), 'Safety and advantages of Bacillus thuringiensis protected plants to control insect pests', Reg. Toxicol. Pharmacol., Vol. 32, pp. 156-173.
23. Gianessi, L. P., Silvers, C. S., Sankula, S. and Carpenter, J. E. (2002), 'Plant biotechnology: Current and potential impact for improving pest management', in 'U.S. Agriculture', National Center for Food & Agriculture Policy (NCFAP), Washington, DC, pp. 1-75.
24. Gianessi, L. P. and Carpenter, J. E. (1999), 'Agricultural Biotechnology: Insect Control Benefits', National Center for Food and Agricultural Policy (NCFAP), Washington, DC.
25. Heimlich, R. E., Fernandez-Cornejo, J., McBride, W. et al. (2000), 'Genetically engineered crops: Has adoption reduced pesticide use?', Agricultural Outlook, August, pp. 13-17.
26. Phipps, R. H. and Park, J. R. (2002), 'Environmental benefits of genetically modified crops: Global and European perspectives on their ability to reduce pesticide use', J. Anim. Feed Sci., Vol. 11, pp. 1-18.
27. Fawcett, R. and Towery, D. (2002), 'Conservation tillage and plant biotechnology: How new technologies can improve the environment by reducing the need to plow', accessed 2003, Purdue University (URL: http:// www.ctic.purdue.edu?CTIC/CTIC.html).
28. Cotton Council (2003), National Cotton Council of America, accessed 2003, Cotton Council (URL: http://www.cotton.org/).
29. Moellenbeck, D. J., Peters, M. L., Birg, J. W. et al. (2001) 'Insecticidal proteins from Bacillus thuringiensis protect corn from corn rootworms', Nat. Biotechnol., Vol. 19, pp, 668-672.
30. Alston, J., Hyde, J. and Marra, M. (2002), 'An ex ante analysis of the benefits from the adoption of Monsanto's corn rootworm resistant varietal technology - YieldGard® Rootworm', Tech. Bull., No. 103, National Science Foundation Center for Integrated Pest Management, Raleigh, NC.
31. Greenplate, J., Penn, S., Shappley, Z. et al. (2000), 'Bollgard II efficacy: Quantifications of total lepidopteran activity in a 2-gene product', Proceedings, Beltwide Cotton Conferences, Vol. 2, pp. 1039-1040.
32. Marchosky, R., Ellsworth, P., Moser, H. and Henneberry, T. (2001), 'Bollgard and Bollgard II. Efficacy in Near Isogenic Lines of DP50 Upland Cotton in Arizona', in '2001 Arizona Cotton Report', pp. 311-315 (URL: http://ag.arizona.edu/pubs/crops/az1224).
33. Moar, W., Voth, R. and Woods, M. (2002), 'Efficacy of August-planted Bollgard II vs. Bollgard I and conventional cotton in Alabama; The acid test', in 'Proceedings of the Beltwide Cotton Production Conference Part 3A - Jan. 8-12, 2002', Atlanta, pp. 1-8.
34. Murphy, D. J. (1996), 'Engineering oil production in rapeseed and other oil crops', Trends Biotechnol., Vol. 14, pp. 206-213.
35. Vasil, I. K. (1996), 'Phosphinothricin-resistant crops', in Duke, S. O., Ed, 'Herbicide-Resistant Crops', CRC Press, Inc., Boca Raton, FL, pp. 85-91.
36. Stalker, D. M., Kiser, J. A., Baldwin, G., Coulombe, B. and Houck, C. M. (1996), 'Cotton weed control using the BXN system', in Duke, S. O., Ed, 'Herbicide-resistant Crops: Agricultural, Environmental, Economic, Regulatory, and Technical Aspects', CRC Press, Inc., Boca Raton, FL, pp. 93-106.
37. Padgette, S., Re, D., Barry, G. et al. (1996), 'New weed control opportunities: Development of soybeans with a Roundup ready gene', in Duke, S. O., Ed, 'Herbicide-resistant Crops: Agricultural, Economic, Regulatory and Technical Aspects', CRC Press, Inc., Boca Raton, FL, pp. 53-84.
38. Kaniewski, W., Maingi, D., Kaniewska, M. et al. (2000), 'Engineered resistance to sweetpotato feathery mottle virus in sweetpotato', in 'Fifth Triennial Congress of the African Potato Association', Kampala, Uganda, p. 37.
39. Qaim, M. (2001), 'A prospective evaluation of biotechnology in semi-subsistence agriculture', Agr. Econ., Vol. 25, pp. 165-175.
40. Gonsalves, D. (1998), 'Control of the papaya ringspot virus in papaya: A case study', Annu. Rev. Phytopathol., Vol. 36, pp. 415-437.
41. Cheikh, N., Miller, P. W. and Kishore, G. (2000), 'Role of biotechnology in crop productivity in a changing environment', in Reddy, K. R. and Hodges, H. F., Eds, 'Climate Change and Global Crop Productivity', CAP International, New York.
42. Falk, M. C., Chassy, B. M., Harlander, S. K., Hoban, T. J. IV, McGloughlin, M. N. and Akhlaghi, A. R. (2002), 'Food biotechnology: Benefits and concerns. Life Sciences Research Office', J. Nutr., Vol. 132, pp. 1384-1390.
43. Gilmour, S. J., Sebolt, A. M., Salazar, M. P., Everard, J. D. and Thomashow, M. F. (2000), 'Overexpression of the Arabidopsis CBF3 transcriptional activator mimics multiple biochemical changes associated with cold acclimation', Plant Physiol., Vol. 124, pp. 1854-1856.
44. Thomashow, M. F. (2001), 'So what's new in the field of plant cold acclimation? Lots!', Plant Physiol., Vol. 125, pp. 89-93.
45. Alia, Hayashi, H., Sakamoto, A. and Murata, N. (1998), 'Enhancement of the tolerance of Arabidopsis to high temperatures by genetic engineering of the synthesis of glycinebetaine', Plant J., Vol. 16, pp. 155-161.
46. Kasuga, M., Liu, Q., Miura, S., Yamaguchi-Shinozaki, K. and Shinozaki, K. (1999), 'Improving plant drought, salt, and freezing tolerance by gene transfer of a single stress inducible transcription factor', Nature Biotechnol., Vol. 17, pp. 287-291.
47. Xu, D., Duan, X., Baiyang, W., Hong, B., Ho, H. T. and Wu, R. (1996), 'Expression of a late embryogenesis abundant protein gene, HVA1, from barley confers tolerance to water deficit and salt stress in transgenic rice', Plant Physiol., Vol. 110, pp. 249-257.
48. Zhang, H. X. and Blumwald, E. (2001), 'Transgenic salt-tolerant tomato plants accumulate salt in foliage butnot in fruit', Nature Biotechnol., Vol. 19, pp. 765-768.
49. Rauch, J. (2003), 'Will Frankenfood save the planet?', Atlantic Monthly, October, pp. 103-108.
50. Tilman, D., Fargione, J., Wolff, B. et al. (2001), 'Forecasting agriculturally driven global environmental change', Science, Vol. 292, pp. 281-284.
51. Bruinsma, J., Ed (2003), 'World Agriculture: Towards 2015/2030, an FAO Perspective', Earthscan, London.
52. Balmford, A. and Long, A. (1994), 'Avian endemism and forest loss', Nature, Vol. 372, p. 623.
53. Jepson, P., Jarvie, J. K., MacKinnon, K. and Monk, K. A. (2001), Science, Vol. 292, p. 859.
54. BirdLife International (2000), 'Threatened Birds of the World', Lynx Edecions/BirdLife International, Barcelona/Cambridge.
55. Fairweather-Tait, S. (2003), 'Why the UK needs a nutrition strategy', Science and Public Affairs, September, The British Association for the Advancement of Science, Norwich.
56. EU COM (2003), 424 Final 2003/0165 (COD) Proposal for a Regulation of the European Parliament and of the Council on nutrition and health claims made on foods.
57. PASSCLAIM (2003), 'Process for the Assessment of Scientific Support for Claims on Foods, Phase One, Preparing the Way. A European Commission Concerted Action Project Coordinated by ILSI Europe', Europ. J. Nutr., Vol. 42, Suppl. 1, March.
58. FAO/WHO (2003), 'Report of the Joint WHO/FAO Expert Consultation on Diet, Nutrition and the Prevention of Chronic Diseases (WHO TRS 916)', WHO, Geneva, 28 January to 1 February 2002.
59. ILSI Europe (2001), 'Genetic Modification Technology and Food. Consumer Health and Safety', Concise Monograph, ILSI, Brussels.
60. Fuchs, R. (2002), 'Foods derived from genetically modified crop plants', in Kotsonis, F. and Mackey, M., Eds, 'Nutritional Toxicology', 2nd edn, Taylor & Francis, Hampshire, Chapter 4, pp. 75-92.
61. Rabjohn, P., West, C. M., Connaughton, C. et al. (2002), 'Modification of peanut allergen Ara h3: Effects on IgE binding and T cell stimulation', Int. Archives Allergy Immunol., Vol. 128, pp. 15-23.
62. Kleiner, K. (2002), 'Engineering safer soya', New Scientist, Vol. 175(2360), p. 7.
63. Tada, Y., Nakase, M., Adachi, T. et al. (1996), 'Reduction of the 14-16 kDa allergenic proteins in transgenic rice plants by antisense gene', FEBS Lett., Vol. 391, pp. 341-345.
64. Buchanan, B. B., Adamidi, C., Lozano, R. M. et al. (1997), 'Thioreduxin-linked mitigation of allergic responses to wheat', Proc. Natl Acad. Sci. USA, Vol. 94, pp. 5372-5377.
65. Budziszewski, G. J., Croft, K. P. C. and Hildebrand, D. F. (1996), 'Uses of biotechnology in modifying plant lipids', Lipids, Vol. 31, pp. 557-569.
66. Kinney, A. J. and Knowlton, S. (1998), 'Designer oils: The high oleic acid soybean', in Roller, S. and Harlander, S. Eds, 'Genetic Modification in the Food Industry', Blackie Academic, London, pp. 193-213.
67. Liu, Q., Singh, S. and Green, A. (2002), 'High-oleic and high-stearic cottonseed oils: Nutritionally improved cooking oils developed using gene silencing', J. Amer. Coll. Nutr., Vol. 21, 3(S), pp. 205S-211S.
68. DuPont Agricultural Products (1996), 'Safety Assessment of High Oleic Acid Transgenic Soybeans', Notification Dossier 62 FR 9155-9156, Docket No. 96-098-1 (URL: http:// www.epa.gov/fedrgstr/EPA-IMPACT/ 1997/February/Day-28/i5023.htm).
69. Lönnerdal, B. (2002), 'Expression of human milk proteins in plants', J. Amer. Coll. Nutr., Vol. 21, 3(S), pp. 218S-221S.
70. Falco, S., Guida, T., Locke, M. et al. (1995), 'Transgenic canola and soybean seeds with increased lysine', Bio/Technology, Vol. 13, pp. 577-582.
71. O'Quinn, P. R., Nelssen, J. L., Goodbank, R. D. et al. (2000), 'Nutritional value of a genetically improved high-lysine, high oil corn for young pigs', J. Anim. Sci., Vol. 78, pp. 2144-2149.
72. Day, P. R. (1996), 'Genetic modification of proteins in food', Crit. Rev. Food Sci. Nutr., Vol. pp. 49-67.
73. Ye, X., Al-Babili, S., Klito, A. et al. (2000), 'Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm', Science, Vol. 287, pp. 303-305.
74. Potrykus, I. (2001), 'Golden Rice and beyond', Plant Physiol., Vol. 125, pp. 1157-1161.
75. Shewmaker, C., Sheehy, J. A., Daley, M., Colburn, S. and Ke, D. Y. (1999), 'Seed-specific overexpression of phytoene synthase: Increase in carotenoids and other metabolic effects', Plant J., Vol. 20(4), pp. 401-412.
76. Mackey, M. (2002), 'The application of biotechnology to nutrition: An overview', J. Amer. Coll. Nutr., Vol. 21, 3(S), pp. 157S-160S.
77. Rocheford, T. R., Wong, J. C., Egesel, C. O. and Lambert, R. J. (2002), 'Enhancement of vitamin E levels in corn', J. Amer. Coll. Nutr., Vol. 21, 3(S), pp. 199S-204S.
78. Shintani, D. and DellaPenna, D. (1998), 'Elevating the vitamin E content of plants through metabolic engineering', Science, Vol. 282, pp. 2098-2100.
79. Lucca, P., Hurrell, R. and Potrykus, I. (2002), 'Fighting iron deficiency anemia with iron-rice rice', J. Amer. Coll. Nutr., Vol. 21, 3(S), pp. 184S-190S.
80. Grusak, M. (2002), 'Enhancing mineral content in plant food products', J. Amer. Coll. Nutr., Vol. 21, 3(S), pp. 178S-183S.
81. Persley, G. J. (2000), 'Agricultural Biotechnology and the Poor', Promethean Science Consultative Group on International Agricultural Research, Washington, DC.
82. Phipps, R. H. and Cockburn, A. (2003), 'GM Technology: A Tool to Benefit Livestock Production', British Society of Animal Science, Nottingham University Press, Nottingham (URL: http:// www.bsas.org.uk/meetings/annlproc/ pdf2003/210.pdf).
83. Gardiner, P. and Devendra, C. (1995), 'Global Agenda for Livestock Research', Proceedings of a Consultation, ILRI, Nairobi, Kenya, 18th-20th January, 1995.
84. Tilman, D. (1999), 'The ecological consequences of changes in biodiversity: A search for general principles', Ecology, Vol. 80(5), pp. 1455-1474.
85. Kalscheur, K. F., Teter, B. B., Piperova, L. S. and Erdman, R. A. (1997), 'Effect of fat source on duodenal flow of trans-C18:1 fatty acids and milk fat production in dairy cows', J. Dairy Sci., Vol. 80, pp. 2115-2126.
86. Payne, J. H. (1977), 'DuPont petition 97-008-01p for determination of nonregulated status for transgenic high oleic acid soybean sublines G94-1, G94-19 and G-168: Environmental assessment and finding of no significant impact', US Department of Agriculture, Animal and Plant Health Inspection Service, Biotechnology and Scientific Services, Riverdale, MD.
87. Wehrspann, J. (1998), 'New traits of seed buying', Farm Industry News, Vol. 31 (10).
88. low T cell-dependent mechanism', J. Immunol., pp. 2116-2126.
89. Streatfield, S. J., Jilka, J. M., Hood, E. E. et al. (2001), 'Plant-based vaccines: Unique advantages', Vaccine, Vol. 19, pp. 2742-2748.
90. Tacket, C. O., Mason, H. S., Losonsky, G. et al. (2000), 'Human immune responses to a novel Norwalk virus vaccine delivered in transgenic potatoes', J. Infect. Dis., Vol. 182, pp. 302-305.
91. Arawaka, T., Chong, D. K. X. and Langridge, W. H. R. (1998), 'Efficacy of a food plant-based oral cholera toxin B subunit vaccine', Nature Biotechnol., Vol. 16, pp. 292-297.
92. Richter, L. J., Thanavala, Y., Arntzen, C. J. and Mason, H. S. (2000), 'Production of Hepatitis B surface antigen in transgenic plants for oral immunization', Nature Biotechnol., Vol. 18, pp. 302-305.
93. Ma, J. K. and Hein, M. B. (1995), 'Therapeutic potential of antibodies produced in plants', Trends Biotechnol., Vol. 13, pp. 522-527.
94. Moffatt, A. S. (1999), 'Engineering plants to cope with metals', Science, Vol. 285(5426), pp. 369-370.
95. Mejare, M. and Bulow, L. (2001), 'Metal-binding proteins and peptides in bioremediation and phytoremediation of heavy metals', Trends Biotechnol., Vol. 19(2), pp. 67-73.
96. Hirsch, K. D., Korenkov, V. D., Wilganowski, N. L. and Wagner, G. J. (2000), 'Expression of Arabidopsis CAX2 in tobacco. Altered metal accumulation and increased manganese tolerance', Plant Physiol., Vol. 124(1), pp. 125-133.
97. Zhy, Y. L., Pilon-Smits, E. A., Tarun, A. S. et al. (1999), 'Cadmium tolerance and accumulation in Indian mustard is enhanced by over expressing gamma-glutamylcysteine synthetase', Plant Physiol., Vol. 121(4), pp. 1169-1178.
98. Commission of the European Communities (2001), 'Proposal for a Directive of the European Parliament and of the Council on the promotion of the use of biofuels for Transport', 7th November, COM(2001) 547.
99. Firbank, L. G., Perry, J. N., Squire, G. R. et al. (2003), 'The implications of spring-sown genetically modified herbicide-tolerant crops for farmland biodiversity: A commentary on the Farm Scale Evaluations of Spring Sown Crops', London (URL: http://www.defra.gov.uk/environment/fse/ index.htm).
100. Dale, P. (2003), 'Submission to ACRE Secretariat. The Farm Scale Evaluations of herbicide tolerant GM Crops', November, Norwich (URL: http:// www.livegroup.co.uk/ acrefarmscale evaluations/SSL/files/ Philip%20J%20Dale%20 Evidence%20101103.pdf).
101. Coghlan, A. (2003), 'GM sugar beet "far more environmentally friendly"', New Scientist, 6th December, p. 17.
102. Raven, P. (2003), 'The Ecology of Agriculture', presentation at the Natural History Museum, Darwin Centre, London, 22nd May.