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Volumn 385, Issue 3-4, 2004, Pages 331-339

Enhanced expression of basolateral multidrug resistance protein isoforms Mrp3 and Mrp5 in rat liver by LPS

Author keywords

ABC transporters; Cholestasis; Hepatobiliary transport; Multidrug resistance proteins

Indexed keywords

CYCLIC NUCLEOTIDE; GLUTAMATE AMMONIA LIGASE; ISOPROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5; MULTIDRUG RESISTANCE PROTEIN 6;

EID: 2542471454     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2004.029     Document Type: Article
Times cited : (58)

References (83)
  • 1
    • 0033977092 scopus 로고    scopus 로고
    • Biliary excretion of bile acids and organic anions in zone 1- and zone 3-injured rats
    • Aiso, M., Takikawa, H., and Yamanaka, M. (2000). Biliary excretion of bile acids and organic anions in zone 1- and zone 3-injured rats. Liver 20, 38-44.
    • (2000) Liver , vol.20 , pp. 38-44
    • Aiso, M.1    Takikawa, H.2    Yamanaka, M.3
  • 2
    • 0036149075 scopus 로고    scopus 로고
    • Transport activity of human MRP3 expressed in Sf9 cells: Comparative studies with rat MRP3
    • Akita, H., Suzuki, H., Hirohashi, T., Takikawa, H., and Sugiyama, Y. (2002). Transport activity of human MRP3 expressed in Sf9 cells: comparative studies with rat MRP3. Pharm. Res. 19, 34-41.
    • (2002) Pharm. Res. , vol.19 , pp. 34-41
    • Akita, H.1    Suzuki, H.2    Hirohashi, T.3    Takikawa, H.4    Sugiyama, Y.5
  • 3
    • 0036296149 scopus 로고    scopus 로고
    • Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response
    • Beigneux, A.P., Moser, A.H., Shigenaga, J.K., Grunfeld, C., and Feingold, K.R. (2002). Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response. Biochem. Biophys. Res. Commun. 293, 145-149.
    • (2002) Biochem. Biophys. Res. Commun. , vol.293 , pp. 145-149
    • Beigneux, A.P.1    Moser, A.H.2    Shigenaga, J.K.3    Grunfeld, C.4    Feingold, K.R.5
  • 4
    • 0036829109 scopus 로고    scopus 로고
    • Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6)
    • Belinsky, M.G., Chen, Z.S., Shchaveleva, I., Zeng, H., and Kruh, G.D. (2002). Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6). Cancer Res. 62, 6172-6177.
    • (2002) Cancer Res. , vol.62 , pp. 6172-6177
    • Belinsky, M.G.1    Chen, Z.S.2    Shchaveleva, I.3    Zeng, H.4    Kruh, G.D.5
  • 6
    • 0141814990 scopus 로고    scopus 로고
    • Tumor necrosis factor α-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis
    • Bohan, A., Chen, W.S., Denson, L.A., Held, M.A., and Boyer, J.L. (2003). Tumor necrosis factor α-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis. J. Biol. Chem. 38, 36688-36698.
    • (2003) J. Biol. Chem. , vol.38 , pp. 36688-36698
    • Bohan, A.1    Chen, W.S.2    Denson, L.A.3    Held, M.A.4    Boyer, J.L.5
  • 7
    • 0040761368 scopus 로고    scopus 로고
    • cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic rats
    • Büchler, M., König, J., Brom, M., Kartenbeck, J., Spring, H., Horie, T., and Keppler, D. (1996). cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic rats. J. Biol. Chem. 271, 15091-15098.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15091-15098
    • Büchler, M.1    König, J.2    Brom, M.3    Kartenbeck, J.4    Spring, H.5    Horie, T.6    Keppler, D.7
  • 9
  • 10
    • 0035823559 scopus 로고    scopus 로고
    • Transport of cyclic nucleotides and estradiol 17-β-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine
    • Chen, Z.S., Lee, K., and Kruh, G.D. (2001). Transport of cyclic nucleotides and estradiol 17-β-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine. J. Biol. Chem. 276, 33747-33754.
    • (2001) J. Biol. Chem. , vol.276 , pp. 33747-33754
    • Chen, Z.S.1    Lee, K.2    Kruh, G.D.3
  • 11
    • 0036606023 scopus 로고    scopus 로고
    • Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system
    • Chen, Z.S., Lee, K., Walther, S., Raftogianis, R.B., Kuwano, M., Zeng, H., and Kruh, G.D. (2002). Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system. Cancer Res. 62, 3144-3150.
    • (2002) Cancer Res. , vol.62 , pp. 3144-3150
    • Chen, Z.S.1    Lee, K.2    Walther, S.3    Raftogianis, R.B.4    Kuwano, M.5    Zeng, H.6    Kruh, G.D.7
  • 12
    • 0034657167 scopus 로고    scopus 로고
    • Electron-microscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide
    • Dombrowski, F., Kubitz, R., Chittattu, A., Wettstein, M., Saha, N., and Häussinger, D. (2000). Electron-microscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide. Biochem. J. 348, 183-188.
    • (2000) Biochem. J. , vol.348 , pp. 183-188
    • Dombrowski, F.1    Kubitz, R.2    Chittattu, A.3    Wettstein, M.4    Saha, N.5    Häussinger, D.6
  • 13
    • 0034928631 scopus 로고    scopus 로고
    • Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver
    • Donner, M.G., and Keppler, D. (2001). Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver. Hepatology 34, 351-359.
    • (2001) Hepatology , vol.34 , pp. 351-359
    • Donner, M.G.1    Keppler, D.2
  • 14
    • 0032694126 scopus 로고    scopus 로고
    • Lipopolysaccharide potentiates the effect of hepatocyte growth factor on hepatocyte replication in rats by augmenting AP-1 activity
    • Gao, C., Jokerst, R., Gondipalli, P., Cai, S.R., Kennedy, S., Flye, M.W., and Ponder, K.P. (1999). Lipopolysaccharide potentiates the effect of hepatocyte growth factor on hepatocyte replication in rats by augmenting AP-1 activity. Hepatology 30, 1405-1416.
    • (1999) Hepatology , vol.30 , pp. 1405-1416
    • Gao, C.1    Jokerst, R.2    Gondipalli, P.3    Cai, S.R.4    Kennedy, S.5    Flye, M.W.6    Ponder, K.P.7
  • 15
    • 0024326541 scopus 로고
    • Hepatic zonation of drug-metabolizing enzymes. Studies on hepatocytes isolated from the periportal or perivenous region of the liver acinus
    • Gascon-Barre, M., Benbrahim, N., and Tremblay, C. (1989). Hepatic zonation of drug-metabolizing enzymes. Studies on hepatocytes isolated from the periportal or perivenous region of the liver acinus. Can. J. Physiol. Pharmacol. 67, 1015-1022.
    • (1989) Can. J. Physiol. Pharmacol. , vol.67 , pp. 1015-1022
    • Gascon-Barre, M.1    Benbrahim, N.2    Tremblay, C.3
  • 16
    • 0020699358 scopus 로고
    • Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture
    • Gebhardt, R., and Mecke, D (1983). Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture. EMBO J. 2, 567-570.
    • (1983) EMBO J. , vol.2 , pp. 567-570
    • Gebhardt, R.1    Mecke, D.2
  • 19
    • 0021969201 scopus 로고
    • Further characterization of the effect of bacterial lipopolysaccharide preparations on cyclic GMP levels: The importance of macromolecular synthesis
    • Graber, S.E., and Clancey, M.A. (1985). Further characterization of the effect of bacterial lipopolysaccharide preparations on cyclic GMP levels: the importance of macromolecular synthesis. Proc. Soc. Exp. Biol. Med. 180, 163-169.
    • (1985) Proc. Soc. Exp. Biol. Med. , vol.180 , pp. 163-169
    • Graber, S.E.1    Clancey, M.A.2
  • 20
  • 21
    • 0020617293 scopus 로고
    • Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver
    • Häussinger, D. (1983) Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver. Eur. J. Biochem. 133, 269-275.
    • (1983) Eur. J. Biochem. , vol.133 , pp. 269-275
    • Häussinger, D.1
  • 22
    • 0024060021 scopus 로고
    • Hepatocyte heterogeneity in response to icosanoids. The perivenous scavenger cell hypothesis
    • Häussinger, D., and Stehle, T. (1988). Hepatocyte heterogeneity in response to icosanoids. The perivenous scavenger cell hypothesis. Eur. J. Biochem. 175, 395-403.
    • (1988) Eur. J. Biochem. , vol.175 , pp. 395-403
    • Häussinger, D.1    Stehle, T.2
  • 23
    • 0024447423 scopus 로고
    • Hepatocyte heterogeneity in glutamate metabolism and bidirectional transport in perfused rat liver
    • Häussinger, D., Stoll, B., Stehle, T., and Gerok, W. (1989). Hepatocyte heterogeneity in glutamate metabolism and bidirectional transport in perfused rat liver. Eur. J. Biochem. 185, 189-195.
    • (1989) Eur. J. Biochem. , vol.185 , pp. 189-195
    • Häussinger, D.1    Stoll, B.2    Stehle, T.3    Gerok, W.4
  • 24
    • 0036786429 scopus 로고    scopus 로고
    • Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia
    • Hartmann, G., Cheung, A.K., and Piquette-Miller, M. (2002). Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia. J. Pharmacol. Exp. Ther. 303, 273-281.
    • (2002) J. Pharmacol. Exp. Ther. , vol.303 , pp. 273-281
    • Hartmann, G.1    Cheung, A.K.2    Piquette-Miller, M.3
  • 26
    • 0031866357 scopus 로고    scopus 로고
    • Hepatic expression of multidrug resistance-associated protein-like proteins maintained in Eisai hyperbilirubinemic rats
    • Hirohashi, T., Suzuki, H., Ito, K., Ogawa, K., Kume, K., Shimizu, T., and Sugiyama, Y. (1998). Hepatic expression of multidrug resistance-associated protein-like proteins maintained in Eisai hyperbilirubinemic rats. Mol. Pharmacol. 53, 1068-1075.
    • (1998) Mol. Pharmacol. , vol.53 , pp. 1068-1075
    • Hirohashi, T.1    Suzuki, H.2    Ito, K.3    Ogawa, K.4    Kume, K.5    Shimizu, T.6    Sugiyama, Y.7
  • 27
    • 0033591235 scopus 로고    scopus 로고
    • Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3)
    • Hirohashi, T., Suzuki, H., and Sugiyama, Y. (1999). Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3). J. Biol. Chem. 274, 15181-5185.
    • (1999) J. Biol. Chem. , vol.274 , pp. 15181-15185
    • Hirohashi, T.1    Suzuki, H.2    Sugiyama, Y.3
  • 28
    • 0034723163 scopus 로고    scopus 로고
    • ATP-dependent transport of bile salts by rat multidrug resistance protein 3 (mrp3)
    • Hirohashi, T., Suzuki, H., Takikawa, H., and Sugiyama, Y. (2000). ATP-dependent transport of bile salts by rat multidrug resistance protein 3 (mrp3). J. Biol. Chem. 275, 2905-2910.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2905-2910
    • Hirohashi, T.1    Suzuki, H.2    Takikawa, H.3    Sugiyama, Y.4
  • 29
    • 0035108792 scopus 로고    scopus 로고
    • Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport
    • Hooiveld, G.J., van Montfoort, J.E., Meijer, D.K., and Müller, M. (2001). Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport. Eur. J. Pharm. Sci. 12, 525-543.
    • (2001) Eur. J. Pharm. Sci. , vol.12 , pp. 525-543
    • Hooiveld, G.J.1    van Montfoort, J.E.2    Meijer, D.K.3    Müller, M.4
  • 30
    • 0037053355 scopus 로고    scopus 로고
    • Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6)
    • Iliás, A., Urban, Z., Seidl, T.L., Le Saux, O., Sinko,E., Boyd, C.D., Sarkadi, B., and Varadi, A. (2002). Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). J. Biol. Chem. 277, 16860-16867.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16860-16867
    • Iliás, A.1    Urban, Z.2    Seidl, T.L.3    Le Saux, O.4    Sinko, E.5    Boyd, C.D.6    Sarkadi, B.7    Varadi, A.8
  • 31
    • 0034730755 scopus 로고    scopus 로고
    • The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides
    • Jedlitschky, G., Burchell, B., and Keppler, D. (2000). The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides. J. Biol. Chem. 275, 30069-30074.
    • (2000) J. Biol. Chem. , vol.275 , pp. 30069-30074
    • Jedlitschky, G.1    Burchell, B.2    Keppler, D.3
  • 32
    • 0024336445 scopus 로고
    • Functional specialization of different hepatocyte populations
    • Jungermann, K., and Katz, N. (1989). Functional specialization of different hepatocyte populations. Physiol. Rev. 69, 708-764.
    • (1989) Physiol. Rev. , vol.69 , pp. 708-764
    • Jungermann, K.1    Katz, N.2
  • 33
    • 0033745088 scopus 로고    scopus 로고
    • Hepatic secretion of conjugated drugs and endogenous substances
    • Keppler, D., and König, J. (2000). Hepatic secretion of conjugated drugs and endogenous substances. Semin. Liver Dis. 20, 265-272.
    • (2000) Semin. Liver Dis. , vol.20 , pp. 265-272
    • Keppler, D.1    König, J.2
  • 34
    • 0032926354 scopus 로고    scopus 로고
    • Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane
    • König, J., Rost, D., Cui, Y., and Keppler, D. (1999a). Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane. Hepatology 29, 1156-1163.
    • (1999) Hepatology , vol.29 , pp. 1156-1163
    • König, J.1    Rost, D.2    Cui, Y.3    Keppler, D.4
  • 35
    • 0344927562 scopus 로고    scopus 로고
    • Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
    • König, J., Nies, A.T., Cui, Y., Leier, I., and Keppler D. (1999b). Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance. Biochim. Biophys. Acta 1461, 377-394.
    • (1999) Biochim. Biophys. Acta , vol.1461 , pp. 377-394
    • König, J.1    Nies, A.T.2    Cui, Y.3    Leier, I.4    Keppler, D.5
  • 36
    • 0030841332 scopus 로고    scopus 로고
    • Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines
    • Kool, M., de Haas, M., Scheffer, G.L., Scheper, R.J., van Eijk, M.J., Juijn, J.A., Baas, F., and Borst, P. (1997). Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res. 57, 3537-3547.
    • (1997) Cancer Res. , vol.57 , pp. 3537-3547
    • Kool, M.1    de Haas, M.2    Scheffer, G.L.3    Scheper, R.J.4    van Eijk, M.J.5    Juijn, J.A.6    Baas, F.7    Borst, P.8
  • 37
    • 0032893268 scopus 로고    scopus 로고
    • Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells
    • Kool, M., van der Linden, M., de Haas, M., Baas, F., and Borst, P. (1999). Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells. Cancer Res. 59, 175-82.
    • (1999) Cancer Res. , vol.59 , pp. 175-182
    • Kool, M.1    van der Linden, M.2    de Haas, M.3    Baas, F.4    Borst, P.5
  • 38
    • 0030731742 scopus 로고    scopus 로고
    • Osmodependent dynamic localisation of the multidrug resistance protein 2 in the rat hepatocyte canalicular membrane
    • Kubitz, R., D'Urso, D., Keppler, D., and Häussinger, D. (1997). Osmodependent dynamic localisation of the multidrug resistance protein 2 in the rat hepatocyte canalicular membrane. Gastroenterology 113, 1438-1442.
    • (1997) Gastroenterology , vol.113 , pp. 1438-1442
    • Kubitz, R.1    D'Urso, D.2    Keppler, D.3    Häussinger, D.4
  • 39
    • 0032944048 scopus 로고    scopus 로고
    • Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone
    • Kubitz, R., Wettstein, M., Warskulat, U., and Häussinger, D. (1999). Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone. Gastroenterology 116, 401-410.
    • (1999) Gastroenterology , vol.116 , pp. 401-410
    • Kubitz, R.1    Wettstein, M.2    Warskulat, U.3    Häussinger, D.4
  • 40
    • 0036471128 scopus 로고    scopus 로고
    • Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues
    • Lai, L., and Tan, T.M. (2002). Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues. Biochem. J. 361, 497-503.
    • (2002) Biochem. J. , vol.361 , pp. 497-503
    • Lai, L.1    Tan, T.M.2
  • 41
    • 0034762163 scopus 로고    scopus 로고
    • Influence of II-6 on MDR and MRP-mediated multidrug resistance in human hepatoma cells
    • Lee, G., and Piquette-Miller, M. (2001). Influence of II-6 on MDR and MRP-mediated multidrug resistance in human hepatoma cells. Can. J. Physiol. Pharmacol. 79, 867-884.
    • (2001) Can. J. Physiol. Pharmacol. , vol.79 , pp. 867-884
    • Lee, G.1    Piquette-Miller, M.2
  • 42
    • 0034007737 scopus 로고    scopus 로고
    • Transport function and hepatocellular localization of mrp6 in rat liver
    • Madon, J., Hagenbuch, B., Landmann, L., Meier, P.J., and Stieger, B. (2000). Transport function and hepatocellular localization of mrp6 in rat liver. Mol. Pharmacol. 57, 634-641.
    • (2000) Mol. Pharmacol. , vol.57 , pp. 634-641
    • Madon, J.1    Hagenbuch, B.2    Landmann, L.3    Meier, P.J.4    Stieger, B.5
  • 43
    • 0033551671 scopus 로고    scopus 로고
    • pABC11 (also known as MOAT-C and MRP5), a member of the ABC family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cells
    • McAleer, M.A., Breen, M.A., White, N.L., and Matthews, N. (1999). pABC11 (also known as MOAT-C and MRP5), a member of the ABC family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cells. J. Biol. Chem. 274, 23541-23548.
    • (1999) J. Biol. Chem. , vol.274 , pp. 23541-23548
    • McAleer, M.A.1    Breen, M.A.2    White, N.L.3    Matthews, N.4
  • 45
    • 0027177507 scopus 로고
    • Hepatocyte heterogeneity in response to extracellular adenosine
    • Morimoto, Y., Wettstein, M., and Häussinger, D. (1993). Hepatocyte heterogeneity in response to extracellular adenosine. Biochem. J. 293, 573-581.
    • (1993) Biochem. J. , vol.293 , pp. 573-581
    • Morimoto, Y.1    Wettstein, M.2    Häussinger, D.3
  • 46
    • 0036614376 scopus 로고    scopus 로고
    • Altered localization and activity of canalicular Mrp2 in estradiol-17-β-D-glucuronide-induced cholestasis
    • Mottino, AD., Cao, J., Veggi, L.M., Crocenzi, F., Roma, M.G., and Vore, M. (2002). Altered localization and activity of canalicular Mrp2 in estradiol-17-β-D-glucuronide-induced cholestasis. Hepatology 35, 1409-1419.
    • (2002) Hepatology , vol.35 , pp. 1409-1419
    • Mottino, A.D.1    Cao, J.2    Veggi, L.M.3    Crocenzi, F.4    Roma, M.G.5    Vore, M.6
  • 50
    • 0034705145 scopus 로고    scopus 로고
    • Pseudoxanthoma elasticum: Mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter
    • Ringpfeil, F., Lebwohl, M.G., Christiano, A.M., and Uitto, J. (2000). Pseudoxanthoma elasticum: mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter. Proc. Natl. Acad. Sci. USA 97, 6001-6006.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6001-6006
    • Ringpfeil, F.1    Lebwohl, M.G.2    Christiano, A.M.3    Uitto, J.4
  • 51
    • 0035095432 scopus 로고    scopus 로고
    • Compound heterozygosity for a recurrent 16.5-kb Alu-mediated deletion mutation and single-base-pair substitutions in the ABCC6 gene results in pseudoxanthoma elasticum
    • Ringpfeil, F., Nakano, A., Uitto, J., and Pulkkinen, L. (2001). Compound heterozygosity for a recurrent 16.5-kb Alu-mediated deletion mutation and single-base-pair substitutions in the ABCC6 gene results in pseudoxanthoma elasticum. Am. J. Hum. Genet. 68, 642-652.
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 642-652
    • Ringpfeil, F.1    Nakano, A.2    Uitto, J.3    Pulkkinen, L.4
  • 52
    • 0042766881 scopus 로고    scopus 로고
    • Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane
    • Rius, M., Nies, A.T., Hummel-Eisenbeiss, J., Jedlitschky, G., and Keppler, D. (2003). Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane. Hepatology 38, 374-384.
    • (2003) Hepatology , vol.38 , pp. 374-384
    • Rius, M.1    Nies, A.T.2    Hummel-Eisenbeiss, J.3    Jedlitschky, G.4    Keppler, D.5
  • 53
    • 0043132421 scopus 로고    scopus 로고
    • The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs
    • Reid, G., Wielinga, P., Zelcer, N., van der Heijden, I., Kuil, A., de Haas, M., Wijnholds, J., and Borst, P. (2003). The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Proc. Natl. Acad. Sci. USA 100, 9244-9249.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9244-9249
    • Reid, G.1    Wielinga, P.2    Zelcer, N.3    van der Heijden, I.4    Kuil, A.5    de Haas, M.6    Wijnholds, J.7    Borst, P.8
  • 55
    • 0035883708 scopus 로고    scopus 로고
    • Enhancement of the activity of doxorubicin by inhibition of glutamate transporter
    • Sadzuka, Y., Sugiyama, T., Suzuki, T., and Sonobe, T. (2001). Enhancement of the activity of doxorubicin by inhibition of glutamate transporter. Toxicol. Lett. 123, 159-167.
    • (2001) Toxicol. Lett. , vol.123 , pp. 159-167
    • Sadzuka, Y.1    Sugiyama, T.2    Suzuki, T.3    Sonobe, T.4
  • 56
    • 0033558792 scopus 로고    scopus 로고
    • Expression of cytokines and activation of transcription factors in lipopolysaccharide-administered rats and their inhibition by phenyl N-tert-butylnitrone (PBN)
    • Sang, H., Wallis, G.L., Stewart, C.A., and Kotake, Y. (1999). Expression of cytokines and activation of transcription factors in lipopolysaccharide-administered rats and their inhibition by phenyl N-tert-butylnitrone (PBN). Arch. Biochem. Biophys. 363, 341-348.
    • (1999) Arch. Biochem. Biophys. , vol.363 , pp. 341-348
    • Sang, H.1    Wallis, G.L.2    Stewart, C.A.3    Kotake, Y.4
  • 60
    • 0033947842 scopus 로고    scopus 로고
    • Retrieval of the mrp2 gene encoded conjugate export pump from the canalicular membrane contributes to cholestasis induced by tert-butyl hydroperoxide and chloro-dinitrobenzene
    • Schmitt, M., Kubitz, R., Wettstein, M., vom Dahl, S., and Häussinger, D. (2000). Retrieval of the mrp2 gene encoded conjugate export pump from the canalicular membrane contributes to cholestasis induced by tert-butyl hydroperoxide and chloro-dinitrobenzene. Biol. Chem. 381, 487-495.
    • (2000) Biol. Chem. , vol.381 , pp. 487-495
    • Schmitt, M.1    Kubitz, R.2    Wettstein, M.3    vom Dahl, S.4    Häussinger, D.5
  • 61
  • 62
    • 0035668415 scopus 로고    scopus 로고
    • The expression levels of plasma membrane transporters in the cholestatic liver of patients undergoing biliary drainage and their association with the impairment of biliary secretory function
    • Shoda, J., Kano, M., Oda, K., Kamiya, J., Nimura, Y., Suzuki, H., Sugiyama, Y., Miyazaki, H., Todoroki, T., Stengelin, S. et al. (2001). The expression levels of plasma membrane transporters in the cholestatic liver of patients undergoing biliary drainage and their association with the impairment of biliary secretory function. Am. J. Gastroenterol. 96, 3368-3378.
    • (2001) Am. J. Gastroenterol. , vol.96 , pp. 3368-3378
    • Shoda, J.1    Kano, M.2    Oda, K.3    Kamiya, J.4    Nimura, Y.5    Suzuki, H.6    Sugiyama, Y.7    Miyazaki, H.8    Todoroki, T.9    Stengelin, S.10
  • 63
    • 0023865471 scopus 로고
    • Distribution of glutamine synthetase and carbamoyl-phosphate synthetase I in vertebrate liver
    • Smith, D.D. Jr., and Campbell, J.W. (1988). Distribution of glutamine synthetase and carbamoyl-phosphate synthetase I in vertebrate liver. Proc. Natl. Acad. Sci. USA 85, 160-164.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 160-164
    • Smith Jr., D.D.1    Campbell, J.W.2
  • 64
    • 0035080391 scopus 로고    scopus 로고
    • Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes; and cholangiocytes during obstructive cholestasis in rat liver
    • Soroka, C.J., Lee, J.M., Azzaroli, F., and Boyer, J. (2001). Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes; and cholangiocytes during obstructive cholestasis in rat liver. Hepatology 33, 783-791.
    • (2001) Hepatology , vol.33 , pp. 783-791
    • Soroka, C.J.1    Lee, J.M.2    Azzaroli, F.3    Boyer, J.4
  • 65
    • 0028157803 scopus 로고
    • Cytokine stimulation of nitric oxide formation and differential regulation in hepatocytes and nonparenchymal cells of endotoxemic rats
    • Spitzer, J.A. (1994). Cytokine stimulation of nitric oxide formation and differential regulation in hepatocytes and nonparenchymal cells of endotoxemic rats. Hepatology 19, 217-228.
    • (1994) Hepatology , vol.19 , pp. 217-228
    • Spitzer, J.A.1
  • 66
    • 0037403746 scopus 로고    scopus 로고
    • Regulation of drug transporter gene expression by nuclear receptors
    • Staudinger, J.L., Madan, A., Carol, K.M., and Parkinson A. (2003). Regulation of drug transporter gene expression by nuclear receptors. Drug Metab. Dispos. 31, 523-527.
    • (2003) Drug Metab. Dispos. , vol.31 , pp. 523-527
    • Staudinger, J.L.1    Madan, A.2    Carol, K.M.3    Parkinson, A.4
  • 67
    • 0024402230 scopus 로고
    • Functional hepatocyte heterogeneity: Vascular 2-oxoglutarate is almost exclusively taken up by perivenous, glutamine-synthetase-containing hepatocytes
    • Stoll, B., and Häussinger, D. (1989). Functional hepatocyte heterogeneity: Vascular 2-oxoglutarate is almost exclusively taken up by perivenous, glutamine-synthetase-containing hepatocytes. Eur. J. Biochem. 181, 709-716.
    • (1989) Eur. J. Biochem. , vol.181 , pp. 709-716
    • Stoll, B.1    Häussinger, D.2
  • 68
    • 0026057552 scopus 로고
    • Hepatocyte heterogeneity in uptake and metabolism of malate and related dicarboxylates
    • Stoll, B., and Häussinger, D. (1991). Hepatocyte heterogeneity in uptake and metabolism of malate and related dicarboxylates. Eur. J. Biochem. 195, 121-129.
    • (1991) Eur. J. Biochem. , vol.195 , pp. 121-129
    • Stoll, B.1    Häussinger, D.2
  • 69
    • 0026101649 scopus 로고
    • Functional hepatocyte heterogeneity in glutamate, aspartate and aketoglutarate uptake: A histoautoradiographical study
    • Stoll, B., McNelly, S., Buscher, H.P., and Häussinger D. (1991). Functional hepatocyte heterogeneity in glutamate, aspartate and aketoglutarate uptake: a histoautoradiographical study. Hepatology 13, 247-253.
    • (1991) Hepatology , vol.13 , pp. 247-253
    • Stoll, B.1    McNelly, S.2    Buscher, H.P.3    Häussinger, D.4
  • 73
    • 0037379362 scopus 로고    scopus 로고
    • Bile salt transporters: Molecular characterization, function, and regulation
    • Trauner, M., and Boyer, J.L. (2003). Bile salt transporters: molecular characterization, function, and regulation. Physiol. Rev. 83, 633-671.
    • (2003) Physiol. Rev. , vol.83 , pp. 633-671
    • Trauner, M.1    Boyer, J.L.2
  • 75
    • 0036299114 scopus 로고    scopus 로고
    • Transcriptional regulation of the rat Mrp3 promoter in intestine cells
    • Tzeng, S.J., and Huang, J.D. (2002). Transcriptional regulation of the rat Mrp3 promoter in intestine cells. Biochem. Biophys. Res. Commun. 291, 270-277.
    • (2002) Biochem. Biophys. Res. Commun. , vol.291 , pp. 270-277
    • Tzeng, S.J.1    Huang, J.D.2
  • 76
    • 0031738416 scopus 로고    scopus 로고
    • Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver
    • Vos, T.A., Hooiveld, G.J.E.J., Koning, H., Childs, S., Meijer, D.K.F., Moshage, H., Jansen, P.L.M., and Müller, M. (1998). Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver. Hepatology 28, 1637-1644.
    • (1998) Hepatology , vol.28 , pp. 1637-1644
    • Vos, T.A.1    Hooiveld, G.J.E.J.2    Koning, H.3    Childs, S.4    Meijer, D.K.F.5    Moshage, H.6    Jansen, P.L.M.7    Müller, M.8
  • 78
    • 0037705377 scopus 로고    scopus 로고
    • Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells
    • Wielinga, P.R., van der Heijden, I., Reid, G., Beijnen, J.H., Wijnholds, J., and Borst, P. (2003). Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells. J. Biol. Chem. 278, 17664-17671.
    • (2003) J. Biol. Chem. , vol.278 , pp. 17664-17671
    • Wielinga, P.R.1    van der Heijden, I.2    Reid, G.3    Beijnen, J.H.4    Wijnholds, J.5    Borst, P.6
  • 80
    • 0035824674 scopus 로고    scopus 로고
    • Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3)
    • Zelcer, N., Saeki, T., Reid, G., Beijnen, J.H., and Borst, P. (2001). Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3). J. Biol. Chem. 276, 46400-46407.
    • (2001) J. Biol. Chem. , vol.276 , pp. 46400-46407
    • Zelcer, N.1    Saeki, T.2    Reid, G.3    Beijnen, J.H.4    Borst, P.5
  • 81
    • 0037693882 scopus 로고    scopus 로고
    • Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4)
    • Zelcer, N., Reid, G., Wielinga, P., Kuil, A., van der Heijden, I., Schuetz, J.D., and Borst P. (2003). Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4). Biochem. J. 371, 361-367.
    • (2003) Biochem. J. , vol.371 , pp. 361-367
    • Zelcer, N.1    Reid, G.2    Wielinga, P.3    Kuil, A.4    van der Heijden, I.5    Schuetz, J.D.6    Borst, P.7
  • 82
    • 0034282991 scopus 로고    scopus 로고
    • Transport of amphipathic anions by human multidrug resistance protein 3
    • Zeng, H., Liu, G., Rea, P.A., and Kruh, G.D. (2000). Transport of amphipathic anions by human multidrug resistance protein 3. Cancer Res. 60, 4779-4784.
    • (2000) Cancer Res. , vol.60 , pp. 4779-4784
    • Zeng, H.1    Liu, G.2    Rea, P.A.3    Kruh, G.D.4


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