Uterine phenotype of young adult rats exposed to dietary soy or genistein during development

Journal of Nutritional Biochemistry

Volumn 16, Issue 10, 2005, Pages 625-632

  Eason, Renea R ^a   Till, S Reneé ^a   Velarde, Michael C ^a,b   Geng, Yan ^a,b   Chatman Jr , Leon ^a   Gu, Liwei ^a,b   Badger, Thomas M ^a,b   Simmen, Frank A ^a,b   Simmen, Rosalia C M ^a,b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Apoptosis; Endocarcinoma; Genistein; Nutrition; Soy; Uterus

Indexed keywords

CASEIN; CYCLINE; ESTRADIOL; ESTROGEN; GENISTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROGESTERONE; PROGESTERONE RECEPTOR; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; SOYBEAN PROTEIN; TUMOR MARKER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER RISK; CONTROLLED STUDY; DIET; ENDOMETRIUM; ESTROGEN BLOOD LEVEL; FEMALE; GENE EXPRESSION; LIFESPAN; MYOMETRIUM; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PROGESTERONE BLOOD LEVEL; RAT; SOYBEAN; TUMOR SUPPRESSOR GENE; UTERUS; UTERUS CARCINOMA; UTERUS GROWTH;

ANIMALS; APOPTOSIS; CASEINS; DIET; ENDOMETRIUM; EPITHELIUM; ESTRADIOL; ESTROGENS; FEMALE; GENISTEIN; MYOMETRIUM; PHENOTYPE; PROGESTERONE; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, SPRAGUE-DAWLEY; SOYBEAN PROTEINS; SOYBEANS; UTERUS;

EID: 25144480483     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2005.03.005     Document Type: Article

References (49)

1. M. Messina, S. Barnes, and K.D. Setchell Phyto-estrogens and breast cancer Lancet 350 1997 971 972
2. A.H. Wu, P. Wan, J. Hankin, C.C. Tseng, M.C. Yu, and M.C. Pike Adolescent and adult soy intake and risk of breast cancers in Asian Americans Carcinogenesis 23 2002 1491 1496
3. X.O. Shu, F. Jin, Q. Dai, W. Wen, J.D. Potter, and L.H. Kushi Soyfood intake during adolescence and subsequent risk of breast cancer among Chinese women Cancer Epidemiol Biomarkers Prev 10 2001 483 488
4. Q. Dai, X.O. Shu, F. Jin, J.D. Potter, L.H. Kushi, and J. Teas Population-based case-control study of food intake and breast cancer risk in Shanghai Br J Cancer 85 2001 372 378
5. G.G.J.M. Kuiper, J. Lemmen, B. Carlsson, J.C. Corton, S.H. Safe, and P.T. van der Saag Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta Endocrinology 139 1998 4252 4263
6. S. Mäkelä, H. Savolanen, E. Aavik, M. Myllärniemi, L. Strauss, and E. Taskinen Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors α and β Proc Natl Acad Sci U S A 96 1999 7077 7082
7. R.C. Santell, Y.C. Chang, M.G. Nair, and W.G. Helferich Dietary genistein exerts estrogenic effects upon the uterus, mammary gland and the hypothalamic/pituitary axis in rats J Nutr 127 1997 263 269
8. P. Diel, K. Smolnikar, T. Schulz, U. Laudenbach-Leschowski, H. Michna, and G. Vollmer Phytoestrogens and carcinogenesis - differential effects of genistein in experimental models of normal malignant rat endometrium Hum Reprod 16 2001 997 1006
9. J.L. Burton, and M. Wells The effect of phytoestrogens on the female genital tract J Clin Pathol 55 2002 401 407
10. C.A. Awoniyi, D. Roberts, D.N. Veeramachaneni, B.S. Hurst, K.E. Tucker, and W.D. Schlaff Reproductive sequelae in female rats after in utero and neonatal exposure to the phytoestrogen genistein Fertil Steril 70 1998 440 447
11. D. Gallo, F. Cantelmo, M. Distefano, C. Ferlini, G.F. Zannoni, and A. Riva Reproductive effects of dietary soy in female Wistar rats Food Chem Toxicol 37 1999 493 502
12. W.N. Jefferson, J.F. Couse, E. Padilla-Banks, K.S. Korach, and R.R. Newbold Neonatal exposure to genistein induces estrogen receptor (ER)-α expression and multioocyte follicles in the maturing mouse ovary: evidence for ERβ-mediated and nonestrogenic actions Biol Reprod 67 2002 1285 1296
13. W.B. Murill, N.M. Brown, J.X. Zhang, P.A. Manzolillo, S. Barnes, and C.A. Lamartiniere Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats Carcinogenesis 17 1996 1451 1457
14. C.E. Wood, T.C. Register, M.S. Anthony, N.D. Kock, and J.M. Cline Breast and uterine effects of soy isoflavones and conjugated equine estrogens in postmenopausal female monkeys J Clin Edocrinol Metab 89 2004 3462 3468
15. M.S. Cotroneo, and C.A. Lamartiniere Pharmacologic, but not dietary, genistein supports endometriosis in a rat model Toxicol Sci 61 2001 68 75
16. R.R. Newbold, E.P. Banks, B. Bullock, and W.N. Jefferson Uterine adenocarcinoma in mice treated neonatally with genistein Cancer Res 61 2001 4325 4328
17. Z. Lian, K. Niwa, K. Tagami, M. Hashimoto, J. Gao, and Y. Yokoyama Preventive effects of isoflavones, genistein and daidzein, on estradiol-17β- related endometrial carcinogenesis in mice Jpn J Cancer Res 92 2001 726 734
18. T.M. Badger, M.J. Ronis, R. Hakkak, J.C. Rowlands, and S. Korourian The health consequences of early soy consumption J Nutr 132 2002 559S 565S
19. P.L. Horn-Ross, E.M. John, A.J. Canchola, S.L. Stewart, and M.M. Lee Phytoestrogen intake and endometrial cancer risk J Natl Cancer Inst 95 2003 1158 1164
20. M.T. Goodman, L.R. Wilkens, J.H. Hankin, L.C. Lyu, A.H. Wu, and L.N. Kolonel Association of soy and fiber consumption with the risk of endometrial cancer Am J Epidemiol 146 1997 294 306
21. T. Kaku, S.G. Silverberg, N. Tsukamoto, N. Tsuruchi, T. Kamura, and T. Saito Association of endometrial epithelial metaplasias with endometrial carcinoma and hyperplasia in Japanese and American women Int J Gynecol Pathol 12 1993 297 300
22. C. Nagata, N. Takatsuka, N. Kawakami, and H. Shimizu Soy product intake and premenopausal hysterectomy in a follow-up study of Japanese women Eur J Clin Nutr 55 2001 773 777
23. K. Kato, S. Takahashi, L. Cui, T. Toda, S. Suzuki, and M. Futakuchi Suppressive effects of dietary genistin and daidzin on rat prostate carcinogenesis Jpn J Cancer Res 91 2000 786 791
24. T. Valachovicova, V. Slivova, H. Bergman, J. Shuberk, and D. Sliva Soy isoflavone suppress invasiveness of breast cancer cells by the inhibition of NF-kappa B/AP-1-dependent and -independent pathways Int J Oncol 25 2004 1389 1395
25. American Academy of Pediatrics Committee on Nutrition Soy protein-based formulas: recommendations for use in infant feeding Pediatrics 101 1998 148 153
26. K.D. Setchell, L. Zimmer-Nechemias, J. Cai, and J.E. Heubi Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life Am J Clin Nutr 68 1998 1453S 1461S
27. C.A. Lamartiniere, J.B. Moore, N.M. Brown, R. Thompson, M.J. Hardin, and S. Barnes Genistein suppresses mammary cancer in rats Carcinogenesis 16 1995 2833 2840
28. P.G. Reeves, F.H. Nielsen, and G.C. Fahey Jr. AIN93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformation of the AIN-76A rodent diet J Nutr 123 1993 1939 1951
29. M.S. Kurzer, and X. Xu Dietary phytoestrogens Annu Rev Nutr 17 1997 353 381
30. R. Hakkak, S. Korourian, S.R. Shelnutt, S. Lansing, M.J. Ronis, and T.M. Badger Diets containing whey proteins or soy protein isolate protect against 7,12- dimethylbenz(a)anthracene-induced mammary tumors in female rats Cancer Epidemiol Biomarkers Prev 9 2000 113 117
31. J.C. Rowlands, R. Hakkak, M.J.J. Ronis, and T.M. Badger Altered mammary gland differentiation and progesterone receptor expression in rats fed soy and whey proteins Toxicol Sci 70 2002 40 45
32. R.R. Eason, M.C. Velarde, L. Chatman Jr., S.R. Till, Y. Geng, M. Ferguson, and T.M. Badger Dietary exposure to whey proteins alters rat mammary gland proliferation, apoptosis, and gene expression during post-natal development: implications for cancer protective mechanisms J Nutr 134 2004 3370 3377
33. R.C.M. Simmen, R.R. Eason, S.R. Till, L. Chatman Jr., M.C. Velarde, and Y. Geng Inhibition of NMU-induced mammary tumorigenesis by dietary soy Cancer Lett 2005 [in press]
34. C.O. Cimino, S.R. Shelnutt, M.J. Ronis, and T.M. Badger An LC-MS method to determine concentrations of isoflavones and their sulfate and glucoronide conjugates in urine Clin Chim Acta 287 1999 69 82
35. S.R. Shelnutt, C.O. Cimino, P.A. Wiggins, M.J. Ronis, and T.M. Badger Pharmacokinetics of the glucoronide and sulfate conjugates of genistein and daidzein in men and women after consumption of a soy beverage Am J Clin Nutr 76 2002 588 594
36. J.A. Hickman Apoptosis and tumourigenesis Curr Opin Genet Dev 12 2002 67 72
37. M.P. Myers, J. Stolarov, C. Eng, J. Li, S.I. Wang, and M.H. Wigler PTEN, the tumor suppressor from human chromosome 10q23, is a dual- specificity phosphatase Proc Natl Acad Sci U S A 94 1997 9052 9057
38. A. Koul, R. Willen, P.O. Bendahl, M. Nilbert, and A. Borg Distinct sets of gene alterations in endometrial carcinoma implicate alternate modes of tumorigenesis Cancer 94 2002 2369 2379
39. J. Xu, and G. Loo Different effects of genistein on molecular markers related to apoptosis in two phenotypically dissimilar breast cancer cell lines J Cell Biochem 82 2001 78 88
40. Y. Li, S. Upadhyay, M. Bhuiyan, and F.H. Sarkar Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein Oncogene 18 1999 3166 3172
41. K.B. Declos, T.J. Bucci, L.G. Lomax, J.R. Latendresse, A. Warbritton, and C.C. Weis Effects of dietary genistein exposure during development on male and female CD (Sprague-Dawley) rats Reprod Toxicol 15 2001 647 663
42. W.A. Fritz, L. Coward, J. Wang, and C.A. Lamartiniere Dietary genistein: perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat Carcinogenesis 19 1998 2151 2158
43. U.A. Kayisli, C.A.H. Aksu, M. Berkkanoglu, and A. Arici Estrogenicity of isoflavones on human endometrial stromal and glandular cells J Clin Endocrinol Metab 87 2002 5539 5544
44. V. Unfer, M.L. Casini, L. Costabile, M. Mignosa, S. Gerli, and G.C. Di Renzo Endometrial effects of long-term treatment with phytoestrogens: a randomized, double-blind, placebo-controlled study Fertil Steril 82 2004 145 148
45. A.M. Duncan, K.E. Underhill, X. Xu, J. Lavalleur, W.R. Phipps, and M.S. Kurzer Modest hormonal effects of soy isoflavones in postmenopausal women J Clin Endocrinol Metab 84 1999 3479 3484
46. +/- mice Cancer Res 60 2000 3605 3611
47. B. Konopka, Z. Baszko, A. Janiec-Jankowska, and M. Goluda Assessment of the quality and frequency of mutation occurrence in PTEN gene in endometrial carcinomas and hyperplasias Cancer Lett 178 2002 43 51
48. F.H. Sarkar, and Y. Li Mechanisms of cancer chemoprevention by soy isoflavone genistein Cancer Metastasis Rev 21 2002 265 280
49. M.S. Anthony, T.B. Clarkson, C.L. Hughes Jr., T.M. Morgan, and G.L. Burke Soybean isoflavones improve cardiovascular risk factors without affecting the reproductive system of peripubertal rhesus monkeys J Nutr 126 1996 43 50