Chemistry of renieramycins. Part 6: Transformation of renieramycin M into jorumycin and renieramycin J including oxidative degradation products, mimosamycin, renierone, and renierol acetate

Tetrahedron

Volumn 60, Issue 17, 2004, Pages 3873-3881

  Saito, Naoki ^a   Tanaka, Chieko ^a   Koizumi, Yu Ichi ^a   Suwanborirux, Khanit ^b   Amnuoypol, Surattana ^b   Pummangura, Sunibhond ^b   Kubo, Akinori ^a  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

^b CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Antitumor activity; Jorumycin; Oxidative degradation; Renieramycin M; Transformation

Indexed keywords

6,7,9,14,14A,15 HEXAHYDRO 9 (HYDROXYMETHYL) 2,11 DIMETHOXY 3,12,16 TRIMETHYL 6,15 IMINO 4H ISOQUINO[3,2 B][3]BENZAZOCINE 1,4,10,13(9H) TETRONE; 7 CYANO 6,7,9,14,14A,15 HEXAHYDRO 9 (HYDROXYMETHYL) 2,11 DIMETHOXY 3,12,16 TRIMETHYL 6,15 IMINO 4H ISOQUINO[3,2 B][3]BENZAZOCINE 1,4,10,13(9H) TETRONE; 9 (ACETOXYMETHYL) 7 CYANO 6,7,9,14,14A,15 HEXAHYDRO 2,11 DIMETHOXY 3,12,16 TRIMETHYL 6,15 IMINO 4H ISOQUINO[3,2 B][3]BENZAZOCINE 1,4,10,13(9H) TETRONE; ISOQUINOLINE ALKALOID; JORUMYCIN; MIMOSAMYCIN; RENIERAMYCIN E; RENIERAMYCIN J; RENIERAMYCIN M; RENIEROL ACETATE; RENIERONE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; DRUG DEGRADATION; DRUG STABILITY; DRUG STRUCTURE; DRUG TRANSFORMATION; HUMAN; HUMAN CELL; OXIDATION; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

EID: 1842580619     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2004.02.071     Document Type: Article

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