Novel design of a pentacyclic scaffold as structural mimic of saframycin A

Tetrahedron

Volumn 59, Issue 41, 2003, Pages 8245-8249

  Ong, Chi Wi ^a   Chang, Yu An ^b   Wu, Jing Yun ^a   Cheng, Chien Chung ^c  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b CHUNG CHOU INSTITUTE OF TECHNOLOGY   (Taiwan)

^c TAMKANG UNIVERSITY   (Taiwan)

Author keywords

5a,12a diazapentacene; DNA binding and scissioning; Saframycin model

Indexed keywords

1,4 DIACETYLPIPERAZINE 2,5 DIONE; 1,4,8,11 TETRAMETHOXY 5,12 DIMETHYL 5,6A,7,12,13A,14 OCTAHYDRO 13 DIOXO 5A,12A DIAZAPENTACENE 6 CARBONITRILE; 2,5 DIMETHOXYBENZALDEHYDE; ANTINEOPLASTIC AGENT; BENZALDEHYDE DERIVATIVE; CWO 324; KETONE; NITRILE; SAFRAMYCIN A; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DNA FLANKING REGION; DRUG DESIGN; DRUG DNA BINDING; DRUG SCREENING; DRUG STRUCTURE; MOLECULAR MIMICRY; PLASMID; PRIORITY JOURNAL;

EID: 0141682312     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2003.08.036     Document Type: Article

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