Exploring the impact of different thioesterase domains for the design of hybrid peptide synthetases

Chemistry and Biology

Volumn 8, Issue 10, 2001, Pages 997-1010

  Schwarzer, Dirk ^a   Mootz, Henning D ^a   Marahiel, Mohamed A ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Domain exchange; Nonribosomal peptide synthesis; Peptide antibiotic; Rational protein engineering

Indexed keywords

CARBOXY TERMINAL SEQUENCE; DIPEPTIDE; GENETIC REGULATION; HETEROLOGOUS EXPRESSION; MACROCYCLIC COMPOUND; MODEL; NONRIBOSOMAL PEPTIDE SYNTHETASE; PROTEIN DOMAIN; REACTION MECHANISM; SPECIFICITY; THIOL ESTER HYDROLASE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; ESCHERICHIA COLI; ESTERASES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; PEPTIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

ILEX COOKII;

EID: 0034802739     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(01)00068-0     Document Type: Article

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