메뉴 건너뛰기




Volumn 272, Issue 17, 2005, Pages 4372-4384

Acute activation of Erk1/Erk2 and protein kinase B/akt proceed by independent pathways in multiple cell types

Author keywords

Cross talk; Cytokine; Inhibitors; Kinase; Phosphorylation

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; CYTOKINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; THREONINE; TYROSINE; WORTMANNIN;

EID: 24644463827     PISSN: 1742464X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2005.04850.x     Document Type: Article
Times cited : (17)

References (51)
  • 2
    • 0031309798 scopus 로고    scopus 로고
    • Mammalian MAP kinase modules: How to transduce specific signals
    • Brunet A & Pouyssegur J (1997) Mammalian MAP kinase modules: how to transduce specific signals. Essays Biochem 32, 1-16.
    • (1997) Essays Biochem , vol.32 , pp. 1-16
    • Brunet, A.1    Pouyssegur, J.2
  • 4
    • 0032407241 scopus 로고    scopus 로고
    • Phosphoinositide lipids as signaling molecules: Common themes for signal transduction, cytoskeletal regulation, and membrane trafficking
    • Martin TFJ (1998) Phosphoinositide lipids as signaling molecules: common themes for signal transduction, cytoskeletal regulation, and membrane trafficking. Annu Rev Cell Dev Biol 14, 231-264.
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 231-264
    • Martin, T.F.J.1
  • 5
    • 0031903015 scopus 로고    scopus 로고
    • Downstream signalling events regulated by phosphatidylinositol 3-kinase activity
    • Duronio V, Scheid MP & Ettinger S (1998) Downstream signalling events regulated by phosphatidylinositol 3-kinase activity. Cell Signal 10, 233-239.
    • (1998) Cell Signal , vol.10 , pp. 233-239
    • Duronio, V.1    Scheid, M.P.2    Ettinger, S.3
  • 6
    • 0029078337 scopus 로고
    • Studies with wortmannin suggest a role for phosphatidylinositol 3-kinase in the activation of glycogen synthase and mitogen-activated protein kinase by insulin in rat adipocytes: Comparison of insulin and protein kinase C modulators
    • Standaert ML, Bandyopadhyay G & Farese RV (1995) Studies with wortmannin suggest a role for phosphatidylinositol 3-kinase in the activation of glycogen synthase and mitogen-activated protein kinase by insulin in rat adipocytes: comparison of insulin and protein kinase C modulators. Biochem Biophys Res Commun 209, 1082-1088.
    • (1995) Biochem Biophys Res Commun , vol.209 , pp. 1082-1088
    • Standaert, M.L.1    Bandyopadhyay, G.2    Farese, R.V.3
  • 7
    • 0030024007 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase blocks T cell antigen receptor/CD3-induced activation of the mitogen-activated kinase Erk2
    • Von Willebrand M, Jascur T, Bonnefoy-Berard N, Yano H, Altman A, Matsuda Y & Mustelin T (1996) Inhibition of phosphatidylinositol 3-kinase blocks T cell antigen receptor/CD3-induced activation of the mitogen-activated kinase Erk2. Eur J Biochem 235, 828-835.
    • (1996) Eur J Biochem , vol.235 , pp. 828-835
    • Von Willebrand, M.1    Jascur, T.2    Bonnefoy-Berard, N.3    Yano, H.4    Altman, A.5    Matsuda, Y.6    Mustelin, T.7
  • 8
    • 0031005028 scopus 로고    scopus 로고
    • Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases
    • Grammer TC & Blenis J (1997) Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases. Oncogene 14, 1635-1642.
    • (1997) Oncogene , vol.14 , pp. 1635-1642
    • Grammer, T.C.1    Blenis, J.2
  • 9
    • 0032500730 scopus 로고    scopus 로고
    • Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK
    • Bondeva T, Pirola L, Bulgarelli-Leva G, Rubio I, Wetzker R & Wymann MP (1998) Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK. Science 282, 293-296.
    • (1998) Science , vol.282 , pp. 293-296
    • Bondeva, T.1    Pirola, L.2    Bulgarelli-Leva, G.3    Rubio, I.4    Wetzker, R.5    Wymann, M.P.6
  • 10
    • 0033548484 scopus 로고    scopus 로고
    • A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf
    • Sutor SL, Vroman BT, Armstrong EA, Abraham RT & Karnitz LM (1999) A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf. J Biol Chem 274, 7002-7010.
    • (1999) J Biol Chem , vol.274 , pp. 7002-7010
    • Sutor, S.L.1    Vroman, B.T.2    Armstrong, E.A.3    Abraham, R.T.4    Karnitz, L.M.5
  • 11
    • 3042799365 scopus 로고    scopus 로고
    • Activation of the MAP kinase pathway by c-Kit is PI-3 kinase dependent in hematopoietic progenitor/stem cell lines
    • Wandzioch E, Edling CE, Palmer RH, Carlsson L & Hallberg B (2004) Activation of the MAP kinase pathway by c-Kit is PI-3 kinase dependent in hematopoietic progenitor/stem cell lines. Blood 104, 51-57.
    • (2004) Blood , vol.104 , pp. 51-57
    • Wandzioch, E.1    Edling, C.E.2    Palmer, R.H.3    Carlsson, L.4    Hallberg, B.5
  • 12
    • 0028308412 scopus 로고
    • Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70, S6 kinase, DNA synthesis, and glucose transporter translocation
    • Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J & Kahn CR (1994) Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70, S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 14, 4902-4911.
    • (1994) Mol Cell Biol , vol.14 , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 13
    • 0029939496 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-OH kinase activity is not required for activation of mitogen-activated protein kinase by cytokines
    • Scheid MP & Duronio V (1996) Phosphatidylinositol 3-OH kinase activity is not required for activation of mitogen-activated protein kinase by cytokines. J Biol Chem 271, 18134-18139.
    • (1996) J Biol Chem , vol.271 , pp. 18134-18139
    • Scheid, M.P.1    Duronio, V.2
  • 14
    • 0031022582 scopus 로고    scopus 로고
    • Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes
    • Frevert EU & Kahn BB (1997) Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes. Mol Cell Biol 17, 190-198.
    • (1997) Mol Cell Biol , vol.17 , pp. 190-198
    • Frevert, E.U.1    Kahn, B.B.2
  • 15
    • 0032189381 scopus 로고    scopus 로고
    • Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
    • Coffer PJ, Jin J & Woodgett JR (1998) Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem J 335, 1-13.
    • (1998) Biochem J , vol.335 , pp. 1-13
    • Coffer, P.J.1    Jin, J.2    Woodgett, J.R.3
  • 16
    • 0035489468 scopus 로고    scopus 로고
    • PKB/AKT: Functional insights from genetic models
    • Scheid MP & Woodgett JR (2001) PKB/AKT: functional insights from genetic models. Nat Rev Mol Cell Biol 2, 760-768.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 760-768
    • Scheid, M.P.1    Woodgett, J.R.2
  • 17
    • 0036295728 scopus 로고    scopus 로고
    • Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation
    • Yang J, Cron P, Thompson V, Good VM, Hess D, Hemmings BA & Barford D (2002) Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation. Mol Cell 9, 1227-1240.
    • (2002) Mol Cell , vol.9 , pp. 1227-1240
    • Yang, J.1    Cron, P.2    Thompson, V.3    Good, V.M.4    Hess, D.5    Hemmings, B.A.6    Barford, D.7
  • 18
    • 0032530482 scopus 로고    scopus 로고
    • Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
    • Delcommenne M, Tan C, Gray V, Rue L, Woodgett J & Dedhar S (1998) Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase. Proc Natl Acad Sci USA 95, 11211-11216.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11211-11216
    • Delcommenne, M.1    Tan, C.2    Gray, V.3    Rue, L.4    Woodgett, J.5    Dedhar, S.6
  • 19
    • 4644359805 scopus 로고    scopus 로고
    • Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase
    • Feng J, Park J, Cron P, Hess D & Hemmings BA (2004) Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase. J Biol Chem 279, 41189-41196.
    • (2004) J Biol Chem , vol.279 , pp. 41189-41196
    • Feng, J.1    Park, J.2    Cron, P.3    Hess, D.4    Hemmings, B.A.5
  • 21
    • 0027992342 scopus 로고
    • Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins
    • Gold MR, Duronio V, Saxena SP, Schrader JW & Aebersold R (1994) Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins. J Biol Chem 269, 5403-5412.
    • (1994) J Biol Chem , vol.269 , pp. 5403-5412
    • Gold, M.R.1    Duronio, V.2    Saxena, S.P.3    Schrader, J.W.4    Aebersold, R.5
  • 22
    • 0029039957 scopus 로고
    • Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway
    • Karnitz LM, Burns LA, Sutor SL, Blenis J & Abraham RT (1995) Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway. Mol Cell Biol 15, 3049-3057.
    • (1995) Mol Cell Biol , vol.15 , pp. 3049-3057
    • Karnitz, L.M.1    Burns, L.A.2    Sutor, S.L.3    Blenis, J.4    Abraham, R.T.5
  • 23
    • 0035968339 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase-dependent regulation of interleukin-3-induced proliferation: Involvement of mitogen-activated protein kinases, SHP2 and Gab2
    • Craddock BL, Hobbs J, Edmead CE & Welham MJ (2001) Phosphoinositide 3-kinase-dependent regulation of interleukin-3-induced proliferation: involvement of mitogen-activated protein kinases, SHP2 and Gab2. J Biol Chem 276, 24274-24283.
    • (2001) J Biol Chem , vol.276 , pp. 24274-24283
    • Craddock, B.L.1    Hobbs, J.2    Edmead, C.E.3    Welham, M.J.4
  • 25
    • 0033607633 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Raf by Akt (protein kinase B)
    • Zimmermann S & Moelling K (1999) Phosphorylation and regulation of Raf by Akt (protein kinase B). Science 286, 1741-1744.
    • (1999) Science , vol.286 , pp. 1741-1744
    • Zimmermann, S.1    Moelling, K.2
  • 26
    • 0037189571 scopus 로고    scopus 로고
    • Convergence of signaling pathways on the activation of ERK in B cells
    • Jacob A, Cooney D, Pradhan M & Coggeshall KM (2002) Convergence of signaling pathways on the activation of ERK in B cells. J Biol Chem 277, 23420-23426.
    • (2002) J Biol Chem , vol.277 , pp. 23420-23426
    • Jacob, A.1    Cooney, D.2    Pradhan, M.3    Coggeshall, K.M.4
  • 28
    • 0030786202 scopus 로고    scopus 로고
    • Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. Dependence on signal strength
    • Duckworth BC & Cantley LC (1997) Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. Dependence on signal strength. J Biol Chem 272, 27665-27670.
    • (1997) J Biol Chem , vol.272 , pp. 27665-27670
    • Duckworth, B.C.1    Cantley, L.C.2
  • 29
    • 0033013866 scopus 로고    scopus 로고
    • Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor
    • Wennstrom S & Downward J (1999) Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor. Mol Cell Biol 19, 4279-4288.
    • (1999) Mol Cell Biol , vol.19 , pp. 4279-4288
    • Wennstrom, S.1    Downward, J.2
  • 30
    • 0022274007 scopus 로고
    • IL-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo
    • Palacios R & Steinmetz M (1985) IL-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo. Cell 41, 727-734.
    • (1985) Cell , vol.41 , pp. 727-734
    • Palacios, R.1    Steinmetz, M.2
  • 31
    • 0036884819 scopus 로고    scopus 로고
    • Regulation of B-cell fate by antigen-receptor signals
    • Niiro H & Clark EA (2002) Regulation of B-cell fate by antigen-receptor signals. Nat Rev Immunol 2, 945-956.
    • (2002) Nat Rev Immunol , vol.2 , pp. 945-956
    • Niiro, H.1    Clark, E.A.2
  • 32
    • 0033817762 scopus 로고    scopus 로고
    • Targets of B-cell antigen receptor signaling: The phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase-3 signaling pathway and the Rap1 GTPase
    • Gold MR, Ingham RJ, McLeod SJ, Christian SL, Scheid MP, Duronio V, Santos L & Matsuuchi L (2000) Targets of B-cell antigen receptor signaling: the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase-3 signaling pathway and the Rap1 GTPase. Immunol Rev 176, 47-68.
    • (2000) Immunol Rev , vol.176 , pp. 47-68
    • Gold, M.R.1    Ingham, R.J.2    McLeod, S.J.3    Christian, S.L.4    Scheid, M.P.5    Duronio, V.6    Santos, L.7    Matsuuchi, L.8
  • 33
    • 0033010661 scopus 로고    scopus 로고
    • Genetic analysis of B cell antigen receptor signaling
    • Kurosaki T (1999) Genetic analysis of B cell antigen receptor signaling. Annu Rev Immunol. 17, 555-592.
    • (1999) Annu Rev Immunol , vol.17 , pp. 555-592
    • Kurosaki, T.1
  • 34
    • 0031471231 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases
    • Li ZM, Wahl MI, Eguinoa A, Stephens LR, Hawkins PT & Witte ON (1997) Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases. Proc Natl Acad Sci USA 94, 13820-13825.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 13820-13825
    • Li, Z.M.1    Wahl, M.I.2    Eguinoa, A.3    Stephens, L.R.4    Hawkins, P.T.5    Witte, O.N.6
  • 37
    • 0035823542 scopus 로고    scopus 로고
    • Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells
    • Reusch HP, Zimmermann S, Schaefer M, Paul M & Moelling K (2001) Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells. J Biol Chem 276, 33630-33637.
    • (2001) J Biol Chem , vol.276 , pp. 33630-33637
    • Reusch, H.P.1    Zimmermann, S.2    Schaefer, M.3    Paul, M.4    Moelling, K.5
  • 39
    • 0035914141 scopus 로고    scopus 로고
    • Insulin, insulin-like growth factor-I, and platelet-derived growth factor activate extracellular signal-regulated kinase by distinct pathways in muscle cells
    • Tsakiridis T, Tsiani E, Lekas P, Bergman A, Cherepanov V, Whiteside C & Downey GP (2001) Insulin, insulin-like growth factor-I, and platelet-derived growth factor activate extracellular signal-regulated kinase by distinct pathways in muscle cells. Biochem Biophys Res Commun 288, 205-211.
    • (2001) Biochem Biophys Res Commun , vol.288 , pp. 205-211
    • Tsakiridis, T.1    Tsiani, E.2    Lekas, P.3    Bergman, A.4    Cherepanov, V.5    Whiteside, C.6    Downey, G.P.7
  • 40
    • 0028963084 scopus 로고
    • Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
    • Yao R & Cooper GM (1995) Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 267, 2003-2006.
    • (1995) Science , vol.267 , pp. 2003-2006
    • Yao, R.1    Cooper, G.M.2
  • 41
    • 0030026693 scopus 로고    scopus 로고
    • Requirement for phosphatidylinositol 3′-kinase to protect hemopoietic progenitors against apoptosis depends upon the extracellular survival factor
    • Minshall C, Arkins S, Freund GG & Kelley KW (1996) Requirement for phosphatidylinositol 3′-kinase to protect hemopoietic progenitors against apoptosis depends upon the extracellular survival factor. J Immunol 156, 939-947.
    • (1996) J Immunol , vol.156 , pp. 939-947
    • Minshall, C.1    Arkins, S.2    Freund, G.G.3    Kelley, K.W.4
  • 42
    • 0029815526 scopus 로고    scopus 로고
    • Oligodendrocytes and their precursors require phosphatidylinositol 3-kinase signaling for survival
    • Vemuri GS & McMorris FA (1996) Oligodendrocytes and their precursors require phosphatidylinositol 3-kinase signaling for survival. Development Suppl 122, 2529-2537.
    • (1996) Development Suppl , vol.122 , pp. 2529-2537
    • Vemuri, G.S.1    McMorris, F.A.2
  • 43
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: Downstream AKTion blocks apoptosis
    • Franke TF, Kaplan DR & Cantley LC (1997) PI3K: downstream AKTion blocks apoptosis. Cell 88, 435-437.
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 44
    • 0032053709 scopus 로고    scopus 로고
    • Mechanisms and consequences of activation of protein kinase B/Akt
    • Downward J (1998) Mechanisms and consequences of activation of protein kinase B/Akt. Curr Opin Cell Biol 10, 262-267.
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 262-267
    • Downward, J.1
  • 45
    • 0028834557 scopus 로고
    • Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in haemopoietic cells: Phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signalling between interleukin-3 and granulocyte- macrophage colony stimulating factor
    • Scheid MP, Lauener RW & Duronio V (1995) Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in haemopoietic cells: phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signalling between interleukin-3 and granulocyte-macrophage colony stimulating factor. Biochem J 312, 159-162.
    • (1995) Biochem J , vol.312 , pp. 159-162
    • Scheid, M.P.1    Lauener, R.W.2    Duronio, V.3
  • 47
    • 0034881019 scopus 로고    scopus 로고
    • Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals
    • Ballif BA & Blenis J (2001) Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals. Cell Growth Differ 12, 397-408.
    • (2001) Cell Growth Differ , vol.12 , pp. 397-408
    • Ballif, B.A.1    Blenis, J.2
  • 48
    • 0028850452 scopus 로고
    • 2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase
    • 2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase. J Biol Chem 270, 25352-25355.
    • (1995) J Biol Chem , vol.270 , pp. 25352-25355
    • Cross, M.J.1    Stewart, A.2    Hodgkin, M.N.3    Kerr, D.J.4    Wakelam, M.J.5
  • 49
    • 0029831167 scopus 로고    scopus 로고
    • Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002
    • Brunn GJ, Williams J, Sabers C, Wiederrecht G, Lawrence JC Jr & Abraham RT (1996) Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. EMBO J 15, 5256-5267.
    • (1996) EMBO J , vol.15 , pp. 5256-5267
    • Brunn, G.J.1    Williams, J.2    Sabers, C.3    Wiederrecht, G.4    Lawrence Jr., J.C.5    Abraham, R.T.6
  • 50
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies SP, Reddy H, Caivano M & Cohen P (2000) Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351, 95-105.
    • (2000) Biochem J , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 51
    • 0035368020 scopus 로고    scopus 로고
    • Distinct roles for extracellular-signal-regulated protein kinase (ERK) mitogen-activated protein kinases and phosphatidylinositol 3-kinase in the regulation of Mc1-1 synthesis
    • Schubert KM & Duronio V (2001) Distinct roles for extracellular-signal-regulated protein kinase (ERK) mitogen-activated protein kinases and phosphatidylinositol 3-kinase in the regulation of Mc1-1 synthesis. Biochem J 356, 473-480.
    • (2001) Biochem J , vol.356 , pp. 473-480
    • Schubert, K.M.1    Duronio, V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.