Defining a Molecular Mechanism of Synergy between Nucleoside and Nonnucleoside AIDS Drugs

Journal of Biological Chemistry

Volumn 279, Issue 8, 2004, Pages 6221-6224

  Basavapathruni, Aravind ^a   Bailey, Christopher M ^a   Anderson, Karen S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; DRUG PRODUCTS; DRUG THERAPY; ENZYME INHIBITION; VIRUSES;

CHAIN TERMINATION; COMBINATION THERAPIES;

BIOCHEMISTRY;

LAMIVUDINE; N [4 CHLORO 3 (3 METHYL 2 BUTENYLOXY)PHENYL] 2 METHYL 3 FURANCARBOTHIOAMIDE; NUCLEOSIDE ANALOG; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; ZALCITABINE; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; DRUG EFFECT; DRUG POTENTIATION; DRUG TARGETING; ENZYME ACTIVE SITE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MOLECULAR MECHANICS; MONOTHERAPY; PRIORITY JOURNAL; VIRUS LOAD; VIRUS REPLICATION; VIRUS RESISTANCE;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADENOSINE TRIPHOSPHATE; ALLOSTERIC SITE; ANTI-HIV AGENTS; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, VIRAL; HIV INFECTIONS; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; KINETICS; MODELS, MOLECULAR; NEVIRAPINE; NUCLEOSIDES; OLIGONUCLEOTIDES; PROTEIN BINDING; REVERSE TRANSCRIPTASE INHIBITORS; TIME FACTORS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 1342325435     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C300523200     Document Type: Article

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