메뉴 건너뛰기




Volumn 10, Issue 5, 2005, Pages 1131-1142

Motexafin gadolinium induces mitochondrially-mediated caspase-dependent apoptosis

Author keywords

Apoptosis; Caspase; Motexafin gadolinium; Q VD OPh; z VAD fmk

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; CYTOCHROME C; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; GADOLINIUM TEXAPHYRIN; LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; QUINOLINE DERIVATIVE;

EID: 24644441687     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-005-0887-2     Document Type: Article
Times cited : (20)

References (27)
  • 1
    • 0036435662 scopus 로고    scopus 로고
    • Motexafin gadolinium reacts with ascorbate to produce reactive oxygen species
    • Magda D, Gerasimchuk N, Lecane P, et al. Motexafin gadolinium reacts with ascorbate to produce reactive oxygen species. Chem Commun (Camb) 2002; 2730-2731.
    • (2002) Chem Commun (Camb) , pp. 2730-2731
    • Magda, D.1    Gerasimchuk, N.2    Lecane, P.3
  • 2
    • 0028216083 scopus 로고
    • Preclinical evaluation of gadolinium (III) texaphyrin complex. A new paramagnetic contrast agent for magnetic resonance imaging
    • Young SW, Sidhu MK, Qing F, et al. Preclinical evaluation of gadolinium (III) texaphyrin complex. A new paramagnetic contrast agent for magnetic resonance imaging. Invest Radiol 1994; 29: 330-338.
    • (1994) Invest Radiol , vol.29 , pp. 330-338
    • Young, S.W.1    Sidhu, M.K.2    Qing, F.3
  • 3
    • 0030013113 scopus 로고    scopus 로고
    • Gadolinium(III) texaphyrin: A tumor selective radiation sensitizer that is detectable by MRI
    • Young SW, Qing F, Harriman A, et al. Gadolinium(III) texaphyrin: A tumor selective radiation sensitizer that is detectable by MRI. Proc Natl Acad Sci USA 1996; 93: 6610-6615.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6610-6615
    • Young, S.W.1    Qing, F.2    Harriman, A.3
  • 4
    • 0035889348 scopus 로고    scopus 로고
    • Redox cycling by motexafin gadolinium enhances cellular response to ionizing radiation by forming reactive oxygen species
    • Magda D, Lepp C, Gerasimchuk N, et al. Redox cycling by motexafin gadolinium enhances cellular response to ionizing radiation by forming reactive oxygen species. Int J Radiat Oncol Biol Phys 2001; 51: 1025-1036.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 1025-1036
    • Magda, D.1    Lepp, C.2    Gerasimchuk, N.3
  • 5
    • 0034797931 scopus 로고    scopus 로고
    • Motexafin gadolinium: A redox active drug that enhances the efficacy of bleomycin and doxorubicin
    • Miller RA, Woodburn KW, Fan Q, et al. Motexafin gadolinium: A redox active drug that enhances the efficacy of bleomycin and doxorubicin. Clin Cancer Res 2001; 7: 3215-3221.
    • (2001) Clin Cancer Res , vol.7 , pp. 3215-3221
    • Miller, R.A.1    Woodburn, K.W.2    Fan, Q.3
  • 6
    • 0035312794 scopus 로고    scopus 로고
    • Effects of Motexafin gadolinium on tumor metabolism and radiation sensitivity
    • Xu S, Zakian K, Thaler H, et al. Effects of Motexafin gadolinium on tumor metabolism and radiation sensitivity. Int J Radiat Oncol Biol Phys 2001; 49: 1381-1390.
    • (2001) Int J Radiat Oncol Biol Phys , vol.49 , pp. 1381-1390
    • Xu, S.1    Zakian, K.2    Thaler, H.3
  • 7
    • 0035300617 scopus 로고    scopus 로고
    • Multicenter phase Ib/II trial of the radiation enhancer motexafin gadolinium in patients with brain metastases
    • Carde P, Timmerman R, Mehta MP, et al. Multicenter phase Ib/II trial of the radiation enhancer motexafin gadolinium in patients with brain metastases. J Clin Oncol 2001; 19: 2074-2083.
    • (2001) J Clin Oncol , vol.19 , pp. 2074-2083
    • Carde, P.1    Timmerman, R.2    Mehta, M.P.3
  • 8
    • 0037102391 scopus 로고    scopus 로고
    • Lead-in phase to randomized trial of motexafin gadolinium and whole-brain radiation for patients with brain metastases: Centralized assessment of magnetic resonance imaging, neurocognitive, and neurologic end points
    • Mehta MP, Shapiro WR, Glantz MJ, et al. Lead-in phase to randomized trial of motexafin gadolinium and whole-brain radiation for patients with brain metastases: Centralized assessment of magnetic resonance imaging, neurocognitive, and neurologic end points. J Clin Oncol 2002; 20: 3445-3453.
    • (2002) J Clin Oncol , vol.20 , pp. 3445-3453
    • Mehta, M.P.1    Shapiro, W.R.2    Glantz, M.J.3
  • 9
    • 0032907689 scopus 로고    scopus 로고
    • A phase I single-dose trial of gadolinium texaphyrin (Gd-Tex), a tumor selective radiation sensitizer detectable by magnetic resonance imaging
    • Rosenthal DI, Nurenberg P, Becerra CR, et al. A phase I single-dose trial of gadolinium texaphyrin (Gd-Tex), a tumor selective radiation sensitizer detectable by magnetic resonance imaging. Clin Cancer Res 1999; 5: 739-745.
    • (1999) Clin Cancer Res , vol.5 , pp. 739-745
    • Rosenthal, D.I.1    Nurenberg, P.2    Becerra, C.R.3
  • 10
    • 0032874534 scopus 로고    scopus 로고
    • Phases IB and II multidose trial of gadolinium texaphyrin, a radiation sensitizer detectable at MR imaging: Preliminary results in brain metastases
    • Viala J, Vanel D, Meingan P, et al. Phases IB and II multidose trial of gadolinium texaphyrin, a radiation sensitizer detectable at MR imaging: Preliminary results in brain metastases. Radiology 1999; 212: 755-759.
    • (1999) Radiology , vol.212 , pp. 755-759
    • Viala, J.1    Vanel, D.2    Meingan, P.3
  • 11
    • 8344244538 scopus 로고    scopus 로고
    • Motexafin gadolinium: A redox-active tumor selective agent for the treatment of cancer
    • Evens AM. Motexafin gadolinium: A redox-active tumor selective agent for the treatment of cancer. Curr Opin Oncol 2004; 16: 576-580.
    • (2004) Curr Opin Oncol , vol.16 , pp. 576-580
    • Evens, A.M.1
  • 12
    • 10644246037 scopus 로고    scopus 로고
    • Motexafin gadolinium: A clinical review of a novel radioenhancer for brain tumors
    • Khuntia D, Mehta M. Motexafin gadolinium: A clinical review of a novel radioenhancer for brain tumors. Expert Rev Anticancer Ther 2004; 4: 981-989.
    • (2004) Expert Rev Anticancer Ther , vol.4 , pp. 981-989
    • Khuntia, D.1    Mehta, M.2
  • 13
    • 0035525733 scopus 로고    scopus 로고
    • Cellular stress response and apoptosis in cancer therapy
    • Herr I, Debatin KM. Cellular stress response and apoptosis in cancer therapy. Blood 2001; 98: 2603-2614.
    • (2001) Blood , vol.98 , pp. 2603-2614
    • Herr, I.1    Debatin, K.M.2
  • 14
    • 0041666539 scopus 로고    scopus 로고
    • Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties
    • Caserta TM, Smith AN, Gultice AD, Reedy MA, Brown TL. Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties. Apoptosis 2003; 8: 345-352.
    • (2003) Apoptosis , vol.8 , pp. 345-352
    • Caserta, T.M.1    Smith, A.N.2    Gultice, A.D.3    Reedy, M.A.4    Brown, T.L.5
  • 15
    • 0028569209 scopus 로고
    • Cross-linking of surface IgG induces apoptosis in a bcl-2 expressing human follicular lymphoma line of mature B cell phenotype
    • Eray M, Tuomikoski T, Wu H, et al. Cross-linking of surface IgG induces apoptosis in a bcl-2 expressing human follicular lymphoma line of mature B cell phenotype. Int Immunol 1994; 6: 1817-1827.
    • (1994) Int Immunol , vol.6 , pp. 1817-1827
    • Eray, M.1    Tuomikoski, T.2    Wu, H.3
  • 16
    • 0018221490 scopus 로고
    • Biology of the human malignant lymphomas. IV. Functional characterization of ten diffuse histiocytic lymphoma cell lines
    • Epstein AL, Levy R, Kim H, et al. Biology of the human malignant lymphomas. IV. Functional characterization of ten diffuse histiocytic lymphoma cell lines. Cancer 1978; 42: 2379-2391.
    • (1978) Cancer , vol.42 , pp. 2379-2391
    • Epstein, A.L.1    Levy, R.2    Kim, H.3
  • 17
    • 0035816440 scopus 로고    scopus 로고
    • Caspases are reversibly inactivated by hydrogen peroxide
    • Borutaite V, Brown GC. Caspases are reversibly inactivated by hydrogen peroxide. FEBS Lett 2001; 500: 114-118.
    • (2001) FEBS Lett , vol.500 , pp. 114-118
    • Borutaite, V.1    Brown, G.C.2
  • 18
    • 0037936652 scopus 로고    scopus 로고
    • ARMER, apoptotic regulator in the membrane of the endoplasmic reticulum, a novel inhibitor of apoptosis
    • Lui HM, Chen J, Wang L, Naumovski L. ARMER, apoptotic regulator in the membrane of the endoplasmic reticulum, a novel inhibitor of apoptosis. Mol Cancer Res 2003; 1: 508-518.
    • (2003) Mol Cancer Res , vol.1 , pp. 508-518
    • Lui, H.M.1    Chen, J.2    Wang, L.3    Naumovski, L.4
  • 19
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO. The biochemistry of apoptosis. Nature 2000; 407: 770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 20
    • 8444220527 scopus 로고    scopus 로고
    • Molecular mechanisms of caspase regulation during apoptosis
    • Riedl SJ, Shi Y. Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 2004; 5: 897-907.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 897-907
    • Riedl, S.J.1    Shi, Y.2
  • 21
    • 0033601746 scopus 로고    scopus 로고
    • Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
    • Slee EA, Harte MT, Kluck RM, et al. Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J Cell Biol 1999; 144: 281-292.
    • (1999) J Cell Biol , vol.144 , pp. 281-292
    • Slee, E.A.1    Harte, M.T.2    Kluck, R.M.3
  • 22
    • 0033582526 scopus 로고    scopus 로고
    • Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis
    • Sun XM, MacFarlane M, Zhuang J, et al. Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J Biol Chem 1999; 274: 5053-5060.
    • (1999) J Biol Chem , vol.274 , pp. 5053-5060
    • Sun, X.M.1    MacFarlane, M.2    Zhuang, J.3
  • 23
    • 0034929314 scopus 로고    scopus 로고
    • The history of Z-VAD-FMK, a tool for understanding the significance of caspase inhibition
    • Van Noorden CJ. The history of Z-VAD-FMK, a tool for understanding the significance of caspase inhibition. Acta Histochem 2001; 103: 241-251.
    • (2001) Acta Histochem , vol.103 , pp. 241-251
    • Van Noorden, C.J.1
  • 24
    • 0032484008 scopus 로고    scopus 로고
    • Inhibition of human caspases by peptide-based and macromolecular inhibitors
    • Garcia-Calvo M, Peterson EP, Leiting B, et al. Inhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem 1998; 273: 32608-32613.
    • (1998) J Biol Chem , vol.273 , pp. 32608-32613
    • Garcia-Calvo, M.1    Peterson, E.P.2    Leiting, B.3
  • 25
    • 0141893342 scopus 로고    scopus 로고
    • A serine protease is involved in the initiation of DNA damage-induced apoptosis
    • de Bruin EC, Meersma D, de Wilde J, et al. A serine protease is involved in the initiation of DNA damage-induced apoptosis. Cell Death Differ 2003; 10: 1204-1212.
    • (2003) Cell Death Differ , vol.10 , pp. 1204-1212
    • De Bruin, E.C.1    Meersma, D.2    De Wilde, J.3
  • 26
    • 0034523818 scopus 로고    scopus 로고
    • Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
    • Korsmeyer SJ, Wei MC, Saito M, et al. Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ 2000; 7: 1166-1173.
    • (2000) Cell Death Differ , vol.7 , pp. 1166-1173
    • Korsmeyer, S.J.1    Wei, M.C.2    Saito, M.3
  • 27
    • 1642491755 scopus 로고    scopus 로고
    • Mitochondrial effectors in caspase-independent cell death
    • Lorenzo HK, Susin SA. Mitochondrial effectors in caspase-independent cell death. FEBS Lett 2004; 557: 14-20.
    • (2004) FEBS Lett , vol.557 , pp. 14-20
    • Lorenzo, H.K.1    Susin, S.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.