Editorial: The history of Z-VAD-FMK, a tool for understanding the significance of caspase inhibition

Acta Histochemica

Volumn 103, Issue 3, 2001, Pages 241-251

  Van Noorden, C J F ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Apoptosis; Caspases; Chromogenic substrates; Cytochemistry; Drug discovery; Fluorogenic substrates; Histochemistry; Protease inhibitors; Proteases; Proteinases

Indexed keywords

BIOCHEMISTRY; CHROMOGENICS; CYTOLOGY; PATHOLOGY; PHYSIOLOGY; SUBSTRATES;

FLUOROGENIC SUBSTRATES;

ENZYME INHIBITION;

CASPASE; CASPASE INHIBITOR; CHROMOGENIC SUBSTRATE; KETONE; PROTEINASE; PROTEINASE INHIBITOR; BENZYLOXYCARBONYLVALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; CYSTEINE PROTEINASE INHIBITOR; PEPTIDE CHLOROMETHYL KETONE;

APOPTOSIS; CYTOCHEMISTRY; CYTOTOXICITY; ENZYME INHIBITION; ENZYME SUBSTRATE; HISTOCHEMISTRY; PROTEIN DEGRADATION; REVIEW; DRUG ANTAGONISM; DRUG DESIGN; EDITORIAL; HISTORY; HUMAN; METABOLISM;

AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; CASPASES; CYSTEINE PROTEINASE INHIBITORS; DRUG DESIGN; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS;

EID: 0034929314     PISSN: 00651281     EISSN: None     Source Type: Journal    
DOI: 10.1078/0065-1281-00601     Document Type: Editorial

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