메뉴 건너뛰기




Volumn 40, Issue 6, 2004, Pages 1027-1029

The cirrhotic hepatocyte: Navigating between Scylla and Charybdis

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILE ACID; CARRIER PROTEIN; CYTOKINE; FAS ANTIGEN; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA;

EID: 2442718696     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(04)00153-9     Document Type: Editorial
Times cited : (6)

References (31)
  • 1
    • 0141594593 scopus 로고    scopus 로고
    • Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury
    • Jaeschke H., Lemasters J.J. Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury. Gastroenterology. 125:2003;1246-1257
    • (2003) Gastroenterology , vol.125 , pp. 1246-1257
    • Jaeschke, H.1    Lemasters, J.J.2
  • 3
    • 0037292362 scopus 로고    scopus 로고
    • Changes in the expression and immunolocalization of protein associated with toxic bile salts-induced apoptosis in rat hepatocytes
    • Oh S.-H., Yun K.-J., Nan J.-X., Sohn D.-H., Lee B.-H. Changes in the expression and immunolocalization of protein associated with toxic bile salts-induced apoptosis in rat hepatocytes. Arch Toxicol. 77:2003;110-115
    • (2003) Arch Toxicol , vol.77 , pp. 110-115
    • Oh, S.-H.1    Yun, K.-J.2    Nan, J.-X.3    Sohn, D.-H.4    Lee, B.-H.5
  • 4
    • 10744225137 scopus 로고    scopus 로고
    • Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation
    • Schoemaker M.H., Gommans W.M., Conde de la Rosa L., Homan M., Klok P., Trautwein C., et al. Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation. J Hepatol. 39:2003;153-161
    • (2003) J Hepatol , vol.39 , pp. 153-161
    • Schoemaker, M.H.1    Gommans, W.M.2    Conde De La Rosa, L.3    Homan, M.4    Klok, P.5    Trautwein, C.6
  • 5
    • 2342615751 scopus 로고    scopus 로고
    • Apoptosis and oncotic necrosis during acute liver injury after bile duct ligation
    • abstract #175
    • Gujral J.S., Farhood A., Jaeschke H. Apoptosis and oncotic necrosis during acute liver injury after bile duct ligation. Hepatology. 38:2003;240A. abstract #175
    • (2003) Hepatology , vol.38
    • Gujral, J.S.1    Farhood, A.2    Jaeschke, H.3
  • 6
    • 0037379362 scopus 로고    scopus 로고
    • Bile salt transporters: Molecular characterization, function and regulation
    • Trauner M., Boyer J.L. Bile salt transporters: molecular characterization, function and regulation. Physiol Rev. 83:2003;633-671
    • (2003) Physiol Rev , vol.83 , pp. 633-671
    • Trauner, M.1    Boyer, J.L.2
  • 8
    • 0031708617 scopus 로고    scopus 로고
    • Cholestasis confers resistance to the rat liver mitochondrial permeability transition
    • Lieser M.J., Park J., Natori S., Jones B.A., Bronk S.F., Gores G.J. Cholestasis confers resistance to the rat liver mitochondrial permeability transition. Gastroenterology. 115:1998;693-701
    • (1998) Gastroenterology , vol.115 , pp. 693-701
    • Lieser, M.J.1    Park, J.2    Natori, S.3    Jones, B.A.4    Bronk, S.F.5    Gores, G.J.6
  • 9
    • 0034745492 scopus 로고    scopus 로고
    • NF-κB is activated in cholestasis and functions to reduce liver injury
    • Miyoshi H., Rust C., Guicciardi M.E., Gores G.J. NF-κB is activated in cholestasis and functions to reduce liver injury. Am J Pathol. 158:2001;967-975
    • (2001) Am J Pathol , vol.158 , pp. 967-975
    • Miyoshi, H.1    Rust, C.2    Guicciardi, M.E.3    Gores, G.J.4
  • 10
    • 0036623358 scopus 로고    scopus 로고
    • Cytokine regulation of pro- and anti-apoptotic genes in rat hepatocytes: NF-κB-regulated inhibitor of apoptosis protein-2 (cIAP2) prevents apoptosis
    • Schoemaker M.H., Ros J.E., Homan M., Trautwein C., Liston P., Poelstra K., et al. Cytokine regulation of pro- and anti-apoptotic genes in rat hepatocytes: NF-κB-regulated inhibitor of apoptosis protein-2 (cIAP2) prevents apoptosis. J Hepatol. 36:2002;742-750
    • (2002) J Hepatol , vol.36 , pp. 742-750
    • Schoemaker, M.H.1    Ros, J.E.2    Homan, M.3    Trautwein, C.4    Liston, P.5    Poelstra, K.6
  • 11
    • 0026689310 scopus 로고
    • Cytokines tumor necrosis factor and interleukin-6 in experimental biliary obstruction in mice
    • Bemelmans M.H., Gouma D.J., Greve J.W., Buurman W.A. Cytokines tumor necrosis factor and interleukin-6 in experimental biliary obstruction in mice. Hepatology. 15:1992;1132-1136
    • (1992) Hepatology , vol.15 , pp. 1132-1136
    • Bemelmans, M.H.1    Gouma, D.J.2    Greve, J.W.3    Buurman, W.A.4
  • 12
    • 0036151709 scopus 로고    scopus 로고
    • Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes
    • Rao Y.-P., Studer E.J., Stravitz R.T., Gupta S., Qiao L., Dent P., Hylemon P.B. Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes. Hepatology. 35:2002;307-314
    • (2002) Hepatology , vol.35 , pp. 307-314
    • Rao, Y.-P.1    Studer, E.J.2    Stravitz, R.T.3    Gupta, S.4    Qiao, L.5    Dent, P.6    Hylemon, P.B.7
  • 13
    • 0038339493 scopus 로고    scopus 로고
    • Bile acids activate the EGF receptor via a TGF-α-dependent mechanism in human cholangiocyte cell lines
    • Werneburg N.W., Yoon J.-H., Higuchi H., Gores G.J. Bile acids activate the EGF receptor via a TGF-α-dependent mechanism in human cholangiocyte cell lines. Am J Physiol. 285:2003;G31-G36
    • (2003) Am J Physiol , vol.285 , pp. 31-G36
    • Werneburg, N.W.1    Yoon, J.-H.2    Higuchi, H.3    Gores, G.J.4
  • 14
    • 2442702177 scopus 로고    scopus 로고
    • Bile acids induce survival signals in hepatic stellate cells through a PKC- and ERK-dependent mechanism
    • abstract #611
    • Svegliati-Baroni G., Ridolfi F., Schoemaker M., Saccomanno S., Homan M., Jansen P.L.M., et al. Bile acids induce survival signals in hepatic stellate cells through a PKC- and ERK-dependent mechanism. Hepatology. 36:2002;316A. abstract #611
    • (2002) Hepatology , vol.36
    • Svegliati-Baroni, G.1    Ridolfi, F.2    Schoemaker, M.3    Saccomanno, S.4    Homan, M.5    Jansen, P.L.M.6
  • 15
    • 0036211298 scopus 로고    scopus 로고
    • Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes
    • Qiao L., Yacoub A., Studer E., Gupta S., Pei X.Y., Grant S., Hylemon P.B., Dent P. Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes. Hepatology. 35:2002;779-789
    • (2002) Hepatology , vol.35 , pp. 779-789
    • Qiao, L.1    Yacoub, A.2    Studer, E.3    Gupta, S.4    Pei, X.Y.5    Grant, S.6    Hylemon, P.B.7    Dent, P.8
  • 16
    • 2442719968 scopus 로고    scopus 로고
    • Primary cirrhotic hepatocytes resist TGFβ-induced apoptosis through a ROS-dependent mechanism
    • Black D., Bird M.A., Samson C.M., Lyman S., Lange P.A., Schrum L.W., et al. Primary cirrhotic hepatocytes resist TGFβ-induced apoptosis through a ROS-dependent mechanism. J Hepatol. 40:2004;942-951
    • (2004) J Hepatol , vol.40 , pp. 942-951
    • Black, D.1    Bird, M.A.2    Samson, C.M.3    Lyman, S.4    Lange, P.A.5    Schrum, L.W.6
  • 17
    • 0035069055 scopus 로고    scopus 로고
    • Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids
    • Sokol R.J., Straka M.S., Dahl R., Devereaux M.W., Yerushalmi B., Gumpricht E., et al. Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids. Pediatr Res. 49:2001;519-531
    • (2001) Pediatr Res , vol.49 , pp. 519-531
    • Sokol, R.J.1    Straka, M.S.2    Dahl, R.3    Devereaux, M.W.4    Yerushalmi, B.5    Gumpricht, E.6
  • 18
    • 0029123537 scopus 로고
    • Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids
    • Sokol R.J., Winklhofer-Roob B.M., Devereaux M.W., McKim J.M. Jr. Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids. Gastroenterology. 109:1995;1249-1256
    • (1995) Gastroenterology , vol.109 , pp. 1249-1256
    • Sokol, R.J.1    Winklhofer-Roob, B.M.2    Devereaux, M.W.3    Mckim Jr., J.M.4
  • 19
    • 0038580372 scopus 로고    scopus 로고
    • Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling
    • Czaja M., Liu H., Wang Y. Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling. Hepatology. 37:2003;1405-1413
    • (2003) Hepatology , vol.37 , pp. 1405-1413
    • Czaja, M.1    Liu, H.2    Wang, Y.3
  • 20
    • 0037405649 scopus 로고    scopus 로고
    • Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes
    • Qiao L., Han S.I., Fang Y., Park J.S., Gupta S., Gilfor D., et al. Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes. Mol Cell Biol. 23:2003;3052-3066
    • (2003) Mol Cell Biol , vol.23 , pp. 3052-3066
    • Qiao, L.1    Han, S.I.2    Fang, Y.3    Park, J.S.4    Gupta, S.5    Gilfor, D.6
  • 21
    • 0041326612 scopus 로고    scopus 로고
    • Protection of rat hepatocytes from apoptosis by inhibition of c-Jun N-terminal kinase
    • Marderstein E.L., Bucher B., Guo Z., Feng X., Reid K., Geller D.A. Protection of rat hepatocytes from apoptosis by inhibition of c-Jun N-terminal kinase. Surgery. 134:2003;280-284
    • (2003) Surgery , vol.134 , pp. 280-284
    • Marderstein, E.L.1    Bucher, B.2    Guo, Z.3    Feng, X.4    Reid, K.5    Geller, D.A.6
  • 23
    • 0037108859 scopus 로고    scopus 로고
    • Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines
    • Harada K., Toyooka S., Shivapurkar N., Maitra A., Reddy J.L., Matta H., et al. Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines. Cancer Res. 62:2002;5897-5901
    • (2002) Cancer Res , vol.62 , pp. 5897-5901
    • Harada, K.1    Toyooka, S.2    Shivapurkar, N.3    Maitra, A.4    Reddy, J.L.5    Matta, H.6
  • 25
    • 0042346302 scopus 로고    scopus 로고
    • The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism
    • Liedtke C., Groger N., Manns M.P., Trautwein C. The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism. J Biol Chem. 278:2003;27593-27604
    • (2003) J Biol Chem , vol.278 , pp. 27593-27604
    • Liedtke, C.1    Groger, N.2    Manns, M.P.3    Trautwein, C.4
  • 27
    • 0033524857 scopus 로고    scopus 로고
    • A comparative study of apoptosis and necrosis in HepG2 cells: Oxidant-induced caspase inactivation leads to necrosis
    • Samali A., Nordgren H., Zhivotovsky B., Peterson E., Orrenius S. A comparative study of apoptosis and necrosis in HepG2 cells: oxidant-induced caspase inactivation leads to necrosis. Biochem Biophys Res Commun. 255:1999;6-11
    • (1999) Biochem Biophys Res Commun , vol.255 , pp. 6-11
    • Samali, A.1    Nordgren, H.2    Zhivotovsky, B.3    Peterson, E.4    Orrenius, S.5
  • 28
  • 29
    • 0037458627 scopus 로고    scopus 로고
    • Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis
    • Van den Berghe T., Kalai M., van Loo G., Declercq W., Vandenabeele P. Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis. J Biol Chem. 278:2003;5622-5629
    • (2003) J Biol Chem , vol.278 , pp. 5622-5629
    • Van Den Berghe, T.1    Kalai, M.2    Van Loo, G.3    Declercq, W.4    Vandenabeele, P.5
  • 30
    • 25744464240 scopus 로고    scopus 로고
    • Reactive oxygen species induce hepatocyte cell death via different mechanisms: A balance between apoptosis and necrosis
    • abstract #866
    • Conde de la Rosa L., Schoemaker M.H., Homan M., Jansen P.L.M., Moshage H. Reactive oxygen species induce hepatocyte cell death via different mechanisms: a balance between apoptosis and necrosis. Hepatology. 38:2003;577A. abstract #866
    • (2003) Hepatology , vol.38
    • Conde De La Rosa, L.1    Schoemaker, M.H.2    Homan, M.3    Jansen, P.L.M.4    Moshage, H.5
  • 31
    • 0042766884 scopus 로고    scopus 로고
    • Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice
    • Gujral J.S., Farhood A., Bajt M.L., Jaeschke H. Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice. Hepatology. 38:2003;355-363
    • (2003) Hepatology , vol.38 , pp. 355-363
    • Gujral, J.S.1    Farhood, A.2    Bajt, M.L.3    Jaeschke, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.