Primary cirrhotic hepatocytes resist TGFβ-induced apoptosis through a ROS-dependent mechanism

Journal of Hepatology

Volumn 40, Issue 6, 2004, Pages 942-951

  Black, Dalliah ^a   Bird, Mark A ^a   Samson, Charles M ^a   Lyman, Suzanne ^a   Lange, Patty A ^a   Schrum, Laura W ^a   Qian, Ting ^b   Lemasters, J J ^a,b   Brenner, David A ^a   Rippe, Richard A ^a   Behrns, Kevin E ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

AdI B SR, adenovirus I B super repressor; AdLuc, adenovirus luciferase; Apoptosis; Caspase; CCl4, carbon tetrachloride; CyA, cyclosporin A; Mitochrondria permeability transition; Reactive oxygen species; Transforming growth factor beta

Indexed keywords

ANTIOXIDANT; CARBON TETRACHLORIDE; CASPASE; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA; TROLOX C; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL GROWTH; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; LIVER CELL DAMAGE; LIVER CIRRHOSIS; LIVER MITOCHONDRION; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ULTRAVIOLET RADIATION;

ANIMALS; APOPTOSIS; CARBON TETRACHLORIDE POISONING; CASPASES; CELL CULTURE TECHNIQUES; HEPATOCYTES; IMMUNOHISTOCHEMISTRY; INTRACELLULAR MEMBRANES; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; MICE; MICE, INBRED BALB C; MITOCHONDRIA, LIVER; PERMEABILITY; REACTIVE OXYGEN SPECIES; TRANSFORMING GROWTH FACTOR BETA;

EID: 2442719968     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(04)00128-X     Document Type: Article

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