Automated analysis of polyethylene glycol-induced inhibition of P-glycoprotein activity in vitro

Journal of Pharmaceutical Sciences

Volumn 92, Issue 1, 2003, Pages 21-26

  Hugger, Erin D ^a,c   Cole, Clayton J ^b   Raub, Thomas J ^b   Burton, Philip S ^b   Borchardt, Ronald T ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b PFIZER INC   (United States)

^c GLAXOSMITHKLINE   (United States)

Author keywords

Caco 2, MDR1 MDCK, and wild type MDCK cells; P glycoprotein; PEG 300; Robotics

Indexed keywords

EXCIPIENT; GLYCOPROTEIN P; MACROGOL; MEMBRANE PROTEIN; PROTEIN DERIVATIVE;

ANIMAL CELL; ARTICLE; BIOASSAY; CELL CULTURE; CELL STRAIN; CELL STRAIN CACO 2; CELL TRANSPORT; CONTROLLED STUDY; DRUG INHIBITION; DRUG PENETRATION; HUMAN; HUMAN CELL; INTESTINE CELL; MUCOSA CELL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN FUNCTION; ROBOTICS; TECAN GENESIS;

EID: 12244302924     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10265     Document Type: Article

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