메뉴 건너뛰기




Volumn 122, Issue 5, 2004, Pages 1266-1276

Death receptor-independent apoptosis in malignant melanoma induced by the small-molecule immune response modifier imiquimod

Author keywords

Apoptosis; Bcl 2; Imiquimod; Immune response modifier; Malignant melanoma

Indexed keywords

BIOLOGICAL RESPONSE MODIFIER; CELL RECEPTOR; DEATH RECEPTOR; IMIQUIMOD; IMMUNE RESPONSE MODIFIER; PROTEIN BCL 2; RESIQUIMOD; TOPICAL AGENT; UNCLASSIFIED DRUG;

EID: 2442555760     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0022-202X.2004.22528.x     Document Type: Article
Times cited : (122)

References (47)
  • 2
    • 0033215243 scopus 로고    scopus 로고
    • Fas-induced apoptosis in human malignant melanoma cell lines is associated with the activation of the p34(cdc2)-related PITSLRE protein kinases
    • Ariza ME, Broome-Powell M, Lahti JM, Kidd VJ, Nelson MA: Fas-induced apoptosis in human malignant melanoma cell lines is associated with the activation of the p34(cdc2)-related PITSLRE protein kinases. J Biol Chem 274:28505-28513, 1999
    • (1999) J Biol Chem , vol.274 , pp. 28505-28513
    • Ariza, M.E.1    Broome-Powell, M.2    Lahti, J.M.3    Kidd, V.J.4    Nelson, M.A.5
  • 4
    • 0030973423 scopus 로고    scopus 로고
    • Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor
    • Bayaert R, Kidd VJ, Cornelis S, et al: Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor. J Biol Chem 272:11694-11697, 1997
    • (1997) J Biol Chem , vol.272 , pp. 11694-11697
    • Bayaert, R.1    Kidd, V.J.2    Cornelis, S.3
  • 7
    • 0036046523 scopus 로고    scopus 로고
    • Imiquimod, a novel immune response modifier, in the treatment of cutaneous metastases of malignant melanoma
    • Bong AB, Bonnekoh B, Franke I, Schön MP, Ulrich J, Gollnick H: Imiquimod, a novel immune response modifier, in the treatment of cutaneous metastases of malignant melanoma. Dermatology 205:135-138, 2002
    • (2002) Dermatology , vol.205 , pp. 135-138
    • Bong, A.B.1    Bonnekoh, B.2    Franke, I.3    Schön, M.P.4    Ulrich, J.5    Gollnick, H.6
  • 8
    • 0019364035 scopus 로고
    • Expression of surface antigens and its relation to parameters of malignancy in human malignant melanoma
    • Bruggen J, Macher E, Sorg C: Expression of surface antigens and its relation to parameters of malignancy in human malignant melanoma. Cancer Immunol Immunother 10:121-127, 1981
    • (1981) Cancer Immunol Immunother , vol.10 , pp. 121-127
    • Bruggen, J.1    Macher, E.2    Sorg, C.3
  • 9
    • 0343485063 scopus 로고    scopus 로고
    • The imidazoquinolines, imiquimod and R-848, induce functional, but not phenotypic, maturation of human epidermal Langerhans cells
    • Burns R, Ferbel B, Tomai M, Miller R, Gaspari A: The imidazoquinolines, imiquimod and R-848, induce functional, but not phenotypic, maturation of human epidermal Langerhans cells. Clin Immunol 94:13-23, 2000
    • (2000) Clin Immunol , vol.94 , pp. 13-23
    • Burns, R.1    Ferbel, B.2    Tomai, M.3    Miller, R.4    Gaspari, A.5
  • 10
    • 0032531854 scopus 로고    scopus 로고
    • The national cancer database report of cutaneous and noncutaneous melanoma
    • Chang AE, Karnell LH, Menck HR: The national cancer database report of cutaneous and noncutaneous melanoma. Cancer 78:1664-1668, 1998
    • (1998) Cancer , vol.78 , pp. 1664-1668
    • Chang, A.E.1    Karnell, L.H.2    Menck, H.R.3
  • 11
    • 2642689658 scopus 로고    scopus 로고
    • Proteases to die for
    • Cryns V, Yuan J: Proteases to die for. Genes Dev 12:1551-1570, 1999
    • (1999) Genes Dev , vol.12 , pp. 1551-1570
    • Cryns, V.1    Yuan, J.2
  • 12
    • 0035422774 scopus 로고    scopus 로고
    • Helenalin triggers a CD95 death receptor-independent apoptosis that is not affected by overexpression of Bcl-XL or Bcl-2
    • Dirsch VM, Stuppner H, Vollmar AM: Helenalin triggers a CD95 death receptor-independent apoptosis that is not affected by overexpression of Bcl-XL or Bcl-2. Cancer Res 61:5817-5823, 2001
    • (2001) Cancer Res , vol.61 , pp. 5817-5823
    • Dirsch, V.M.1    Stuppner, H.2    Vollmar, A.M.3
  • 13
    • 0035340285 scopus 로고    scopus 로고
    • The role of NF-κB in TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of malignant melanoma
    • Franco AV, Zhang XD, van Berkel E, et al: The role of NF-κB in TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of malignant melanoma. J Immunol 166:5337-5345, 2001
    • (2001) J Immunol , vol.166 , pp. 5337-5345
    • Franco, A.V.1    Zhang, X.D.2    Van Berkel, E.3
  • 15
    • 0029032284 scopus 로고
    • Cellular requirements for cytokine production in response to the immunomodulators imiquimod and S-27609
    • Gibson SJ, Imbertson LM, Wagner TL: Cellular requirements for cytokine production in response to the immunomodulators imiquimod and S-27609. J Interferon Cytokine Res 15:537-645, 1995
    • (1995) J Interferon Cytokine Res , vol.15 , pp. 537-645
    • Gibson, S.J.1    Imbertson, L.M.2    Wagner, T.L.3
  • 16
    • 0032530612 scopus 로고    scopus 로고
    • Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
    • Griffith TS, Chin WA, Jackson GC, Lynch DH, Kubin MZ: Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J Immunol 161: 2833-2840, 1998
    • (1998) J Immunol , vol.161 , pp. 2833-2840
    • Griffith, T.S.1    Chin, W.A.2    Jackson, G.C.3    Lynch, D.H.4    Kubin, M.Z.5
  • 18
    • 0036008014 scopus 로고    scopus 로고
    • Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
    • Hemmi H, Kaisho T, Takeuchi O, et al: Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 3:196-200, 2002
    • (2002) Nat Immunol , vol.3 , pp. 196-200
    • Hemmi, H.1    Kaisho, T.2    Takeuchi, O.3
  • 19
    • 0023942890 scopus 로고
    • Glycoprotein P3.58, associated with tumor progression in malignant melanoma, is a novel leukocyte activation antigen
    • Holzmann B, Lehmann JM, Ziegler-Heitbrock HW, Funke I, Riethmüller G, Johnson JP: Glycoprotein P3.58, associated with tumor progression in malignant melanoma, is a novel leukocyte activation antigen. Int J Cancer 41:542-547, 1988
    • (1988) Int J Cancer , vol.41 , pp. 542-547
    • Holzmann, B.1    Lehmann, J.M.2    Ziegler-Heitbrock, H.W.3    Funke, I.4    Riethmüller, G.5    Johnson, J.P.6
  • 20
    • 0037372013 scopus 로고    scopus 로고
    • Apoptosis and melanoma: Molecular mechanisms
    • Hussein MR, Haemel AK, Wood GS: Apoptosis and melanoma: Molecular mechanisms. J Pathol 199:275-288, 2003
    • (2003) J Pathol , vol.199 , pp. 275-288
    • Hussein, M.R.1    Haemel, A.K.2    Wood, G.S.3
  • 21
    • 0031900829 scopus 로고    scopus 로고
    • Cytokine induction in hairless mouse and rat skin after topical application of the immune response modifiers imiquimod and S-28463
    • Imbertson LM, Beaurline JM, Couture AM, et al: Cytokine induction in hairless mouse and rat skin after topical application of the immune response modifiers imiquimod and S-28463. J Invest Dermatol 110:734-739, 1998
    • (1998) J Invest Dermatol , vol.110 , pp. 734-739
    • Imbertson, L.M.1    Beaurline, J.M.2    Couture, A.M.3
  • 22
    • 0034630167 scopus 로고    scopus 로고
    • Induction of apoptosis by cancer chemotherapy
    • Kaufmann SH, Earnshaw WC: Induction of apoptosis by cancer chemotherapy. Exp Cell Res 256:42-49, 2000
    • (2000) Exp Cell Res , vol.256 , pp. 42-49
    • Kaufmann, S.H.1    Earnshaw, W.C.2
  • 23
    • 0028919610 scopus 로고
    • Stimulation of interferon and cytokine gene expression by imiquimod and stimulation by sendai virus utilize similar signal transaction pathways
    • Megyeri K, Au W-C, Rosztoczy I: Stimulation of interferon and cytokine gene expression by imiquimod and stimulation by sendai virus utilize similar signal transaction pathways. Mol Cell Biol 15:2207-2218, 1995
    • (1995) Mol Cell Biol , vol.15 , pp. 2207-2218
    • Megyeri, K.1    Au, W.-C.2    Rosztoczy, I.3
  • 24
    • 0002228496 scopus 로고
    • Cytokine induction by imiquimod, preclinical results and pharmacology
    • Miller RL, Birmachu W, Gibson S: Cytokine induction by imiquimod, preclinical results and pharmacology. Chemother J 4:148-149, 1994
    • (1994) Chemother J , vol.4 , pp. 148-149
    • Miller, R.L.1    Birmachu, W.2    Gibson, S.3
  • 25
    • 0028335717 scopus 로고
    • Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
    • Miyashita T, Krajewski S, Krajewski M, et al: Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9: 1799-1805, 1994
    • (1994) Oncogene , vol.9 , pp. 1799-1805
    • Miyashita, T.1    Krajewski, S.2    Krajewski, M.3
  • 26
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct trascriptional activator of the human bax gene
    • Miyashita T, Reed JC: Tumor suppressor p53 is a direct trascriptional activator of the human bax gene. Cell 80:293-299, 1995
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 27
    • 0033782397 scopus 로고    scopus 로고
    • Bcl-2 transfected HaCaT keratinocytes resist apoptotic signals of ceramides, tumor necrosis factor alpha, and 1-alpha, 25-dihydroxyvitamin D(3)
    • Müller-Wieprecht V, Riebeling C, Stooss A, Orfanos CE, Geilen CC: Bcl-2 transfected HaCaT keratinocytes resist apoptotic signals of ceramides, tumor necrosis factor alpha, and 1-alpha, 25-dihydroxyvitamin D(3). Arch Dermatol Res 292:455-462, 2000
    • (2000) Arch Dermatol Res , vol.292 , pp. 455-462
    • Müller-Wieprecht, V.1    Riebeling, C.2    Stooss, A.3    Orfanos, C.E.4    Geilen, C.C.5
  • 28
    • 0033554886 scopus 로고    scopus 로고
    • Abnormalities in the p34cdc2-related PITSLRE protein kinase gene complex (CDC2L) on chromosome band 1p36 in melanoma
    • Nelson MA, Ariza ME, Yang J-M, et al: Abnormalities in the p34cdc2-related PITSLRE protein kinase gene complex (CDC2L) on chromosome band 1p36 in melanoma. Cancer Genet Cytogenet 108:91-99, 1999
    • (1999) Cancer Genet Cytogenet , vol.108 , pp. 91-99
    • Nelson, M.A.1    Ariza, M.E.2    Yang, J.-M.3
  • 29
    • 0035720233 scopus 로고    scopus 로고
    • The bax/bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis
    • Raisova M, Hossini AM, Eberle J, et al: The bax/bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis. J Invest Dermatol 117:333-340, 2001
    • (2001) J Invest Dermatol , vol.117 , pp. 333-340
    • Raisova, M.1    Hossini, A.M.2    Eberle, J.3
  • 31
    • 0037194354 scopus 로고    scopus 로고
    • The bisphosphonate pamidronate induces apoptosis in human melanoma cells in vitro
    • Riebeling C, Forsea AM, Raisova M, Orfanos CE, Geilen CC: The bisphosphonate pamidronate induces apoptosis in human melanoma cells in vitro. Br J Cancer 87:366-371, 2002
    • (2002) Br J Cancer , vol.87 , pp. 366-371
    • Riebeling, C.1    Forsea, A.M.2    Raisova, M.3    Orfanos, C.E.4    Geilen, C.C.5
  • 32
    • 0029824158 scopus 로고    scopus 로고
    • A phase I clinical trial of imiquimod, an oral interferon inducer, administered daily
    • Savage P, Horton V, Moore J, Owens M, Witt P, Gore ME: A phase I clinical trial of imiquimod, an oral interferon inducer, administered daily. Br J Cancer 74:1482-1486, 1996
    • (1996) Br J Cancer , vol.74 , pp. 1482-1486
    • Savage, P.1    Horton, V.2    Moore, J.3    Owens, M.4    Witt, P.5    Gore, M.E.6
  • 33
    • 0033779012 scopus 로고    scopus 로고
    • Management of malignant melanoma: New developments in immune and gene therapy
    • Schneeberger A, Goos M, Stingl G, Wagner SN: Management of malignant melanoma: New developments in immune and gene therapy. Clin Exp Dermatol 25:509-519, 2000
    • (2000) Clin Exp Dermatol , vol.25 , pp. 509-519
    • Schneeberger, A.1    Goos, M.2    Stingl, G.3    Wagner, S.N.4
  • 34
    • 0041920772 scopus 로고    scopus 로고
    • Tumor-selective induction of apoptosis and the small-molecule immune response modifier imiquimod
    • Schön M, Bong AB, Drewniok C, et al: Tumor-selective induction of apoptosis and the small-molecule immune response modifier imiquimod. J Natl Cancer Inst 95:1138-1149, 2003
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1138-1149
    • Schön, M.1    Bong, A.B.2    Drewniok, C.3
  • 35
    • 0033861952 scopus 로고    scopus 로고
    • Death and decoy receptors and p53-mediated apoptosis
    • Sheikh MS, Fornace AJ: Death and decoy receptors and p53-mediated apoptosis. Leukemia 14:1509-1513, 2000
    • (2000) Leukemia , vol.14 , pp. 1509-1513
    • Sheikh, M.S.1    Fornace, A.J.2
  • 36
    • 0000293602 scopus 로고    scopus 로고
    • Alterations of Fas (Apo-1/CD95) gene in cutaneous malignant melanoma
    • Shin MS, Park WS, Kim SY, et al: Alterations of Fas (Apo-1/CD95) gene in cutaneous malignant melanoma. Am J Pathol 154:1785-1791, 1999
    • (1999) Am J Pathol , vol.154 , pp. 1785-1791
    • Shin, M.S.1    Park, W.S.2    Kim, S.Y.3
  • 37
    • 0035879830 scopus 로고    scopus 로고
    • Application of a topically-applied immune response modifier, resiquimod gel, to modify the recurrence rate of genital herpes: A pilot study
    • Spruance SL, Tyring SK, Smith MH, Meng TC: Application of a topically-applied immune response modifier, resiquimod gel, to modify the recurrence rate of genital herpes: A pilot study. J Infect Dis 184:196-200, 2001
    • (2001) J Infect Dis , vol.184 , pp. 196-200
    • Spruance, S.L.1    Tyring, S.K.2    Smith, M.H.3    Meng, T.C.4
  • 39
    • 0034120295 scopus 로고    scopus 로고
    • Imiquimod, a topical immune response modifier, induces migration of Langerhans cells
    • Suzuki H, Wang B, Shivji GM, et al: Imiquimod, a topical immune response modifier, induces migration of Langerhans cells. J Invest Dermatol 114:135-141, 2000
    • (2000) J Invest Dermatol , vol.114 , pp. 135-141
    • Suzuki, H.1    Wang, B.2    Shivji, G.M.3
  • 40
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1462, 1995
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 41
    • 0028875151 scopus 로고
    • Immunomodulating and antiviral activities of the imidazoquinoline S-28463
    • Tomai MA, Gibson SJ, Imbertson LM: Immunomodulating and antiviral activities of the imidazoquinoline S-28463. Antiviral Res 28:253-264, 1995
    • (1995) Antiviral Res , vol.28 , pp. 253-264
    • Tomai, M.A.1    Gibson, S.J.2    Imbertson, L.M.3
  • 42
    • 0036053251 scopus 로고    scopus 로고
    • Topical imiquimod eradicates skin metastases of malignant melanoma but fails to prevent rapid lymphogenous metastatic spread
    • Ugurel S, Wagner A, Pföhler C, Tilgen W, Reinhold U: Topical imiquimod eradicates skin metastases of malignant melanoma but fails to prevent rapid lymphogenous metastatic spread. Br J Dermatol 147:621-624, 2002
    • (2002) Br J Dermatol , vol.147 , pp. 621-624
    • Ugurel, S.1    Wagner, A.2    Pföhler, C.3    Tilgen, W.4    Reinhold, U.5
  • 44
    • 0033540341 scopus 로고    scopus 로고
    • Modulation of TH1 and TH2 cytokine production with the immune response modifiers, R-848 and imiquimod
    • Wagner TL, Ahonen CL, Couture AM, et al: Modulation of TH1 and TH2 cytokine production with the immune response modifiers, R-848 and imiquimod. Cell Immunol 191:10-19, 1999
    • (1999) Cell Immunol , vol.191 , pp. 10-19
    • Wagner, T.L.1    Ahonen, C.L.2    Couture, A.M.3
  • 45
    • 0031282514 scopus 로고    scopus 로고
    • Induction of cytokines in Cynomolgus monkeys by the immune response modifiers, imiquimod, S-27609 and S-28463
    • Wagner TL, Horton VL, Carlson GL: Induction of cytokines in Cynomolgus monkeys by the immune response modifiers, imiquimod, S-27609 and S-28463. Cytokine 9:837-845, 1997
    • (1997) Cytokine , vol.9 , pp. 837-845
    • Wagner, T.L.1    Horton, V.L.2    Carlson, G.L.3
  • 46
    • 0028070090 scopus 로고
    • Induction of interferon and other cytokines by imiquimod and its hydroxylated metabolite R-842 in human blood cells in vitro
    • Weeks CE, Gibson SJ: Induction of interferon and other cytokines by imiquimod and its hydroxylated metabolite R-842 in human blood cells in vitro. J Interferon Res 14:81-85, 1994
    • (1994) J Interferon Res , vol.14 , pp. 81-85
    • Weeks, C.E.1    Gibson, S.J.2
  • 47
    • 0000005230 scopus 로고    scopus 로고
    • Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells
    • Zhang XD, Franco AV, Nguyen T, Gray CP, Hersey P: Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells. J Immunol 164:3961-3970, 2000
    • (2000) J Immunol , vol.164 , pp. 3961-3970
    • Zhang, X.D.1    Franco, A.V.2    Nguyen, T.3    Gray, C.P.4    Hersey, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.