Death and decoy receptors and p53-mediated apoptosis

Leukemia

Volumn 14, Issue 8, 2000, Pages 1509-1513

  Sheikh, M S ^a   Fornace, A J ^b  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Death domain; TNF R superfamily

Indexed keywords

CELL SURFACE PROTEIN; CYSTEINE; FAS ANTIGEN; FAS LIGAND; GLYCOSYLPHOSPHATIDYLINOSITOL; LIGAND; MEMBRANE RECEPTOR; OSTEOPROTEGERIN; PROTEIN P53; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; APOPTOSIS; CELL DEATH; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REVIEW; SIGNAL TRANSDUCTION;

EID: 0033861952     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401865     Document Type: Review

References (49)

1. Apoptosis by death factor
2. Apoptosis Control by death and decoy receptors
3. The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation
4. FADD, a novel death domain-containing protein, interacts with death domains of Fas and initiates apoptosis
5. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
6. Signaling pathway for apoptosis: A racetrack for life or death
7. The death domain kinase RIP mediates the TNF-induced NF-κB signal
8. Prevention of constitutive TNF receptor 1 signaling by silencer of death domain
9. NF-(K)B antiapoptosis induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase 8 activation
10. Modulation of life and death by the TNF receptor supferfamily
11. Daxx, a novel Fas-binding protein that activates JNK and apoptosis
12. Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx
13. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95
14. TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas (Apo-1/CD95)
15. Identification of a ligand for the death-domain-containing receptor Apo3
16. To die or not to die - the quest of the TRAIL receptors
17. FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis
18. TRAIL induces apoptosis and activation of NF-kappa B
19. Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappa B and JNK activation and apoptosis through district pathways
20. Identification and functional characterization of DR6, a novel death domain-containing TNF receptor
21. An antagonist decoy receptor and a death domain-containing receptor for TRAIL
22. Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family
23. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
24. TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signaling
25. The novel receptor TRAIL-R4 induces NFkB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
26. A novel receptor for Apo2L/TRAIL contains a truncated death domain
27. Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer
28. Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
29. p53: Puzzled and paradigm
30. Regulation of p53 downstream genes
31. p53 and apoptosis
32. The complexity of p53 modulation: Emerging patterns from divergent signals
33. Role of p53-family members in apoptotis
34. Induction of apoptosis in HeLa cells by trans-activation-deficient p53
35. p53-defendent apoptosis in the absence of transcriptional activation of p53-target genes
36. Involvement of the CD95 (APO1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells
37. p53 activates the CD95 (APO1/Fas) gene in response to DNA damage by anticancer drugs
38. Wild-type p53 and a temperature sensitive mutant induce Fas/APO-1 expression
39. KILLER/DR5 is DNA damage-inducible p53-regulated death receptor gene
40. p53-dependent and independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and TNFα
41. The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of gastrointestinal tract
42. The TRAIL decoy receptor TRUNDD (DcR2, TRAIL-R10 is induced by denovirus-p53 overexpressession and can delay TRAIL-, p53-, and KILLER/DR5-dependent colon cancer apoptosis
43. DNA damage signals induction of Fas ligand in tumor cells
44. Cell surface trafficking of Fas: A rapid mechanism of p53-mediated apoptosis
45. p53-dependent DNA damage-induced apoptosis requires Fas/APO-1-independent activation of CPP32
46. p53-mediated up-regulation of CD95 is not involved in genotoxic drug-induced apoptosis of human breast tumor cells
47. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
48. The apoptosis-associated gamma-ray response of BCL-X(L), depends on normal p53 function
49. Bcl-2 family proteins