메뉴 건너뛰기




Volumn 296, Issue 2, 2004, Pages 151-162

Expression of active plasminogen activator inhibitor-1 reduces cell migration and invasion in breast and gynecological cancer cells

Author keywords

Breast, ovarian, cervical, and endometrial cancer cell lines; PAI 1; Plasminogen activator inhibitors; Plasminogen activator system; Serine proteases; Serpins; Urokinase

Indexed keywords

ADENOVIRUS VECTOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN P14; TRANSFORMING GROWTH FACTOR BETA; VITRONECTIN;

EID: 2442545196     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.02.022     Document Type: Article
Times cited : (50)

References (72)
  • 1
    • 0030469517 scopus 로고    scopus 로고
    • The fibrinolytic system in neoplasia
    • Bell W.R. The fibrinolytic system in neoplasia. Semin. Thromb. Hemostasis. 22:1996;459-478
    • (1996) Semin. Thromb. Hemostasis , vol.22 , pp. 459-478
    • Bell, W.R.1
  • 2
    • 0033981473 scopus 로고    scopus 로고
    • The plasminogen activation system in tumor growth, invasion, and metastasis
    • Andreasen P.A., Egelund R., Petersen H.H. The plasminogen activation system in tumor growth, invasion, and metastasis. Cell. Mol. Life Sci. 57:2000;25-40
    • (2000) Cell. Mol. Life Sci. , vol.57 , pp. 25-40
    • Andreasen, P.A.1    Egelund, R.2    Petersen, H.H.3
  • 3
    • 0029745109 scopus 로고    scopus 로고
    • The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin
    • Stefansson S., Lawrence D.A. The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin. Nature. 383:1996;441-443
    • (1996) Nature , vol.383 , pp. 441-443
    • Stefansson, S.1    Lawrence, D.A.2
  • 4
    • 0037416209 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 detaches cells from extracellular matrices by inactivating integrins
    • Czekay R.P., Aertgeerts K., Curriden S.A., Loskutoff D.J. Plasminogen activator inhibitor-1 detaches cells from extracellular matrices by inactivating integrins. J. Cell Biol. 160:2003;781-791
    • (2003) J. Cell Biol. , vol.160 , pp. 781-791
    • Czekay, R.P.1    Aertgeerts, K.2    Curriden, S.A.3    Loskutoff, D.J.4
  • 5
    • 0030842795 scopus 로고    scopus 로고
    • Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration
    • Chapman H.A. Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration. Curr. Opin. Cell Biol. 9:1997;714-724
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 714-724
    • Chapman, H.A.1
  • 6
    • 0023654279 scopus 로고
    • CDNA cloning and expression in Escherichia coli of a plasminogen activator inhibitor from human placenta
    • Ye R.D., Wun T.C., Sadler J.E. cDNA cloning and expression in Escherichia coli of a plasminogen activator inhibitor from human placenta. J. Biol. Chem. 262:1987;3718-3725
    • (1987) J. Biol. Chem. , vol.262 , pp. 3718-3725
    • Ye, R.D.1    Wun, T.C.2    Sadler, J.E.3
  • 7
    • 0028874970 scopus 로고
    • Plasminogen activator inhibitor type 2 inhibits tumor necrosis factor alpha-induced apoptosis: Evidence for an alternate biological function
    • Dickinson J.L., Bates E.J., Ferrante A., Antalis T.M. Plasminogen activator inhibitor type 2 inhibits tumor necrosis factor alpha-induced apoptosis: evidence for an alternate biological function. J. Biol. Chem. 270:1995;27894-27904
    • (1995) J. Biol. Chem. , vol.270 , pp. 27894-27904
    • Dickinson, J.L.1    Bates, E.J.2    Ferrante, A.3    Antalis, T.M.4
  • 8
    • 0030779751 scopus 로고    scopus 로고
    • Assessment of the interaction between urokinase and reactive site mutants of protein C inhibitor
    • Jackson T.P., Cooper S.T., Church F.C. Assessment of the interaction between urokinase and reactive site mutants of protein C inhibitor. J. Protein Chem. 16:1997;819-828
    • (1997) J. Protein Chem. , vol.16 , pp. 819-828
    • Jackson, T.P.1    Cooper, S.T.2    Church, F.C.3
  • 9
    • 0033591327 scopus 로고    scopus 로고
    • Two distinct urokinase-serpin interactions regulate the initiation of cell surface-associated plasminogen activation
    • Schwartz B.S., Espana F. Two distinct urokinase-serpin interactions regulate the initiation of cell surface-associated plasminogen activation. J. Biol. Chem. 274:1999;15278-15283
    • (1999) J. Biol. Chem. , vol.274 , pp. 15278-15283
    • Schwartz, B.S.1    Espana, F.2
  • 10
    • 0037175016 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 and -3 increase cell adhesion and motility of MDA-MB-435 breast cancer cells
    • Palmieri D., Lee J.W., Juliano R.L., Church F.C. Plasminogen activator inhibitor-1 and -3 increase cell adhesion and motility of MDA-MB-435 breast cancer cells. J. Biol. Chem. 277:2002;40950-40957
    • (2002) J. Biol. Chem. , vol.277 , pp. 40950-40957
    • Palmieri, D.1    Lee, J.W.2    Juliano, R.L.3    Church, F.C.4
  • 11
    • 0031692103 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 is an independent poor prognostic factor for survival in advanced stage epithelial ovarian cancer patients
    • Chambers S.K., Ivins C.M., Carcangiu M.L. Plasminogen activator inhibitor-1 is an independent poor prognostic factor for survival in advanced stage epithelial ovarian cancer patients. Int. J. Cancer. 79:1998;449-454
    • (1998) Int. J. Cancer , vol.79 , pp. 449-454
    • Chambers, S.K.1    Ivins, C.M.2    Carcangiu, M.L.3
  • 12
    • 0035874046 scopus 로고    scopus 로고
    • Dedifferentiation of serous ovarian cancer from cystic to solid tumors is associated with increased expression of mRNA for urokinase plasminogen activator (uPA), its receptor (uPAR) and its inhibitor (PAI-1)
    • Borgfeldt C., Hansson S.R., Gustavsson B., Masback A., Casslen B. Dedifferentiation of serous ovarian cancer from cystic to solid tumors is associated with increased expression of mRNA for urokinase plasminogen activator (uPA), its receptor (uPAR) and its inhibitor (PAI-1). Int. J. Cancer. 92:2001;497-502
    • (2001) Int. J. Cancer , vol.92 , pp. 497-502
    • Borgfeldt, C.1    Hansson, S.R.2    Gustavsson, B.3    Masback, A.4    Casslen, B.5
  • 13
    • 0034901514 scopus 로고    scopus 로고
    • Association of urokinase-type plasminogen activator and its inhibitor with disease progression and prognosis in ovarian cancer
    • Konecny G., Untch M., Pihan A., Kimmig R., Gropp M., Stieber P., Hepp H., Slamon D., Pegram M. Association of urokinase-type plasminogen activator and its inhibitor with disease progression and prognosis in ovarian cancer. Clin. Cancer Res. 7:2001;1743-1749
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1743-1749
    • Konecny, G.1    Untch, M.2    Pihan, A.3    Kimmig, R.4    Gropp, M.5    Stieber, P.6    Hepp, H.7    Slamon, D.8    Pegram, M.9
  • 14
    • 0031769894 scopus 로고    scopus 로고
    • High tissue content of urokinase plasminogen activator (u-PA) is associated with high stromal expression of u-PA mRNA in poorly differentiated serous ovarian carcinoma
    • Borgfeldt C., Casslen B., Liu C.L., Hansson S., Lecander I., Astedt B. High tissue content of urokinase plasminogen activator (u-PA) is associated with high stromal expression of u-PA mRNA in poorly differentiated serous ovarian carcinoma. Int. J. Cancer. 79:1998;588-595
    • (1998) Int. J. Cancer , vol.79 , pp. 588-595
    • Borgfeldt, C.1    Casslen, B.2    Liu, C.L.3    Hansson, S.4    Lecander, I.5    Astedt, B.6
  • 15
    • 0033017371 scopus 로고    scopus 로고
    • Urokinase and plasminogen activator-inhibitor (PAI-1) status in primary ovarian carcinomas and ovarian metastases compared to benign ovarian tumors as a function of histopathological parameters
    • Hoffmann G., Pollow K., Weikel W., Strittmatter H.J., Bach J., Schaffrath M., Knapstein P., Melchert F., Pollow B. Urokinase and plasminogen activator-inhibitor (PAI-1) status in primary ovarian carcinomas and ovarian metastases compared to benign ovarian tumors as a function of histopathological parameters. Clin. Chem. Lab. Med. 37:1999;47-54
    • (1999) Clin. Chem. Lab. Med. , vol.37 , pp. 47-54
    • Hoffmann, G.1    Pollow, K.2    Weikel, W.3    Strittmatter, H.J.4    Bach, J.5    Schaffrath, M.6    Knapstein, P.7    Melchert, F.8    Pollow, B.9
  • 17
  • 18
    • 0035167384 scopus 로고    scopus 로고
    • Clinical relevance of urokinase-type plasminogen activator, its receptor, and its inhibitor type 1 in endometrial cancer
    • Tecimer C., Doering D.L., Goldsmith L.J., Meyer J.S., Abdulhay G., Wittliff J.L. Clinical relevance of urokinase-type plasminogen activator, its receptor, and its inhibitor type 1 in endometrial cancer. Gynecol. Oncol. 80:2001;48-55
    • (2001) Gynecol. Oncol. , vol.80 , pp. 48-55
    • Tecimer, C.1    Doering, D.L.2    Goldsmith, L.J.3    Meyer, J.S.4    Abdulhay, G.5    Wittliff, J.L.6
  • 20
    • 0027305466 scopus 로고
    • Plasminogen activator inhibitors in endometrial adenocarcinoma
    • Gleeson N.C., Gonsalves R., Bonnar J. Plasminogen activator inhibitors in endometrial adenocarcinoma. Cancer. 72:1993;1670-1672
    • (1993) Cancer , vol.72 , pp. 1670-1672
    • Gleeson, N.C.1    Gonsalves, R.2    Bonnar, J.3
  • 22
    • 0036817327 scopus 로고    scopus 로고
    • Clinical relevance of urokinase-type plasminogen activator and its inhibitor type 1 (PAI-1) in squamous cell carcinoma of the uterine cervix
    • Horn L.C., Pippig S., Raptis G., Fischer U., Kohler U., Hentschel B., Martin R. Clinical relevance of urokinase-type plasminogen activator and its inhibitor type 1 (PAI-1) in squamous cell carcinoma of the uterine cervix. Aust. N. Z. J. Obstet. Gynaecol. 42:2002;383-386
    • (2002) Aust. N. Z. J. Obstet. Gynaecol. , vol.42 , pp. 383-386
    • Horn, L.C.1    Pippig, S.2    Raptis, G.3    Fischer, U.4    Kohler, U.5    Hentschel, B.6    Martin, R.7
  • 23
    • 0028639208 scopus 로고
    • Impact of urokinase-type plasminogen activator and its inhibitor type 1 on prognosis in cervical cancer of the uterus
    • Kobayashi H., Fujishiro S., Terao T. Impact of urokinase-type plasminogen activator and its inhibitor type 1 on prognosis in cervical cancer of the uterus. Cancer Res. 54:1994;6539-6548
    • (1994) Cancer Res. , vol.54 , pp. 6539-6548
    • Kobayashi, H.1    Fujishiro, S.2    Terao, T.3
  • 24
    • 0025995880 scopus 로고
    • Clinical relevance of the urokinase-type and tissue-type plasminogen activators and of their type 1 inhibitor in breast cancer
    • Janicke F., Schmitt M., Graeff H. Clinical relevance of the urokinase-type and tissue-type plasminogen activators and of their type 1 inhibitor in breast cancer. Semin. Thromb. Hemost. 17:1991;303-312
    • (1991) Semin. Thromb. Hemost. , vol.17 , pp. 303-312
    • Janicke, F.1    Schmitt, M.2    Graeff, H.3
  • 26
    • 0036329424 scopus 로고    scopus 로고
    • Urokinase plasminogen activator and its inhibitor, PAI-1, as prognostic markers in breast cancer: From pilot to level 1 evidence studies
    • Duffy M.J. Urokinase plasminogen activator and its inhibitor, PAI-1, as prognostic markers in breast cancer: from pilot to level 1 evidence studies. Clin. Chem. 48:2002;1194-1197
    • (2002) Clin. Chem. , vol.48 , pp. 1194-1197
    • Duffy, M.J.1
  • 29
    • 0037434421 scopus 로고    scopus 로고
    • Independent prognostic value of angiogenesis and the level of plasminogen activator inhibitor type 1 in breast cancer patients
    • Hansen S., Overgaard J., Rose C., Knoop A., Laenkholm A.V., Andersen J., Sorensen F.B., Andreasen P.A. Independent prognostic value of angiogenesis and the level of plasminogen activator inhibitor type 1 in breast cancer patients. Br. J. Cancer. 88:2003;102-108
    • (2003) Br. J. Cancer , vol.88 , pp. 102-108
    • Hansen, S.1    Overgaard, J.2    Rose, C.3    Knoop, A.4    Laenkholm, A.V.5    Andersen, J.6    Sorensen, F.B.7    Andreasen, P.A.8
  • 31
    • 0037102368 scopus 로고    scopus 로고
    • Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424)
    • Harbeck N., Kates R.E., Look M.P., Meijer-Van Gelder M.E., Klijn J.G., Kruger A., Kiechle M., Janicke F., Schmitt M., Foekens J.A. Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424). Cancer Res. 62:2002;4617-4622
    • (2002) Cancer Res. , vol.62 , pp. 4617-4622
    • Harbeck, N.1    Kates, R.E.2    Look, M.P.3    Meijer-Van Gelder, M.E.4    Klijn, J.G.5    Kruger, A.6    Kiechle, M.7    Janicke, F.8    Schmitt, M.9    Foekens, J.A.10
  • 32
    • 0037434428 scopus 로고    scopus 로고
    • Accumulation of uPA-PAI-1 complexes inside the tumour cells is associated with axillary nodal invasion in progesterone-receptor-positive early breast cancer
    • Schneider J., Pollan M., Tejerina A., Sanchez J., Lucas A.R. Accumulation of uPA-PAI-1 complexes inside the tumour cells is associated with axillary nodal invasion in progesterone-receptor-positive early breast cancer. Br. J. Cancer. 88:2003;96-101
    • (2003) Br. J. Cancer , vol.88 , pp. 96-101
    • Schneider, J.1    Pollan, M.2    Tejerina, A.3    Sanchez, J.4    Lucas, A.R.5
  • 36
    • 0028900705 scopus 로고
    • Co-expression of urokinase, urokinase receptor and PAI-1 is necessary for optimum invasiveness of cultured lung cancer cells
    • Liu G., Shuman M.A., Cohen R.L. Co-expression of urokinase, urokinase receptor and PAI-1 is necessary for optimum invasiveness of cultured lung cancer cells. Int. J. Cancer. 60:1995;501-506
    • (1995) Int. J. Cancer , vol.60 , pp. 501-506
    • Liu, G.1    Shuman, M.A.2    Cohen, R.L.3
  • 37
    • 0030017987 scopus 로고    scopus 로고
    • Urokinase-type plasminogen activation in three human breast cancer cell lines correlates with their in vitro invasiveness
    • Holst-Hansen C., Johannessen B., Hoyer-Hansen G., Romer J., Ellis V., Brunner N. Urokinase-type plasminogen activation in three human breast cancer cell lines correlates with their in vitro invasiveness. Clin. Exp. Metastasis. 14:1996;297-307
    • (1996) Clin. Exp. Metastasis , vol.14 , pp. 297-307
    • Holst-Hansen, C.1    Johannessen, B.2    Hoyer-Hansen, G.3    Romer, J.4    Ellis, V.5    Brunner, N.6
  • 38
    • 0031985864 scopus 로고    scopus 로고
    • Estrogen and progestin inhibit invasiveness of gynecologic metastatic cancer cells to blood vessel endothelium
    • Fujimoto J., Hori M., Ichigo S., Morishita S., Tamaya T. Estrogen and progestin inhibit invasiveness of gynecologic metastatic cancer cells to blood vessel endothelium. Eur. J. Gynaecol. Oncol. 19:1998;42-45
    • (1998) Eur. J. Gynaecol. Oncol. , vol.19 , pp. 42-45
    • Fujimoto, J.1    Hori, M.2    Ichigo, S.3    Morishita, S.4    Tamaya, T.5
  • 39
    • 0029091325 scopus 로고
    • Thrombospondin and transforming growth factor-beta 1 increase expression of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in human MDA-MB-231 breast cancer cells
    • Arnoletti J.P., Albo D., Granick M.S., Solomon M.P., Castiglioni A., Rothman V.L., Tuszynski G.P. Thrombospondin and transforming growth factor-beta 1 increase expression of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in human MDA-MB-231 breast cancer cells. Cancer. 76:1995;998-1005
    • (1995) Cancer , vol.76 , pp. 998-1005
    • Arnoletti, J.P.1    Albo, D.2    Granick, M.S.3    Solomon, M.P.4    Castiglioni, A.5    Rothman, V.L.6    Tuszynski, G.P.7
  • 40
    • 0032473479 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 enhances the invasiveness of human MDA-MB-231 breast cancer cells by up-regulating urokinase activity
    • Farina A.R., Coppa A., Tiberio A., Tacconelli A., Turco A., Colletta G., Gulino A., Mackay A.R. Transforming growth factor-beta1 enhances the invasiveness of human MDA-MB-231 breast cancer cells by up-regulating urokinase activity. Int. J. Cancer. 75:1998;721-730
    • (1998) Int. J. Cancer , vol.75 , pp. 721-730
    • Farina, A.R.1    Coppa, A.2    Tiberio, A.3    Tacconelli, A.4    Turco, A.5    Colletta, G.6    Gulino, A.7    MacKay, A.R.8
  • 42
    • 0033548625 scopus 로고    scopus 로고
    • The very low density lipoprotein receptor regulates urokinase receptor catabolism and breast cancer cell motility in vitro
    • Webb D.J., Nguyen D.H., Sankovic M., Gonias S.L. The very low density lipoprotein receptor regulates urokinase receptor catabolism and breast cancer cell motility in vitro. J. Biol. Chem. 274:1999;7412-7420
    • (1999) J. Biol. Chem. , vol.274 , pp. 7412-7420
    • Webb, D.J.1    Nguyen, D.H.2    Sankovic, M.3    Gonias, S.L.4
  • 43
    • 0032478829 scopus 로고    scopus 로고
    • Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility
    • Nguyen D.H., Hussaini I.M., Gonias S.L. Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility. J. Biol. Chem. 273:1998;8502-8507
    • (1998) J. Biol. Chem. , vol.273 , pp. 8502-8507
    • Nguyen, D.H.1    Hussaini, I.M.2    Gonias, S.L.3
  • 45
    • 0038558477 scopus 로고    scopus 로고
    • Urokinase-mediated posttranscriptional regulation of urokinase-receptor expression in non small cell lung carcinoma
    • Montuori N., Mattiello A., Mancini A., Taglialatela P., Caputi M., Rossi G., Ragno P. Urokinase-mediated posttranscriptional regulation of urokinase-receptor expression in non small cell lung carcinoma. Int. J. Cancer. 105:2003;353-360
    • (2003) Int. J. Cancer , vol.105 , pp. 353-360
    • Montuori, N.1    Mattiello, A.2    Mancini, A.3    Taglialatela, P.4    Caputi, M.5    Rossi, G.6    Ragno, P.7
  • 46
    • 0038547793 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression in breast cancer
    • Bartsch J.E., Staren E.D., Appert H.E. Matrix metalloproteinase expression in breast cancer. J. Surg. Res. 110:2003;383-392
    • (2003) J. Surg. Res. , vol.110 , pp. 383-392
    • Bartsch, J.E.1    Staren, E.D.2    Appert, H.E.3
  • 48
    • 0027945176 scopus 로고
    • Serpin reactive center loop mobility is required for inhibitor function but not for enzyme recognition
    • Lawrence D.A., Olson S.T., Palaniappan S., Ginsburg D. Serpin reactive center loop mobility is required for inhibitor function but not for enzyme recognition. J. Biol. Chem. 269:1994;27657-27662
    • (1994) J. Biol. Chem. , vol.269 , pp. 27657-27662
    • Lawrence, D.A.1    Olson, S.T.2    Palaniappan, S.3    Ginsburg, D.4
  • 49
    • 0030898213 scopus 로고    scopus 로고
    • Characterization of the binding of different conformational forms of plasminogen activator inhibitor-1 to vitronectin. Implications for the regulation of pericellular proteolysis
    • Lawrence D.A., Palaniappan S., Stefansson S., Olson S.T., Francis-Chmura A.M., Shore J.D., Ginsburg D. Characterization of the binding of different conformational forms of plasminogen activator inhibitor-1 to vitronectin. Implications for the regulation of pericellular proteolysis. J. Biol. Chem. 272:1997;7676-7680
    • (1997) J. Biol. Chem. , vol.272 , pp. 7676-7680
    • Lawrence, D.A.1    Palaniappan, S.2    Stefansson, S.3    Olson, S.T.4    Francis-Chmura, A.M.5    Shore, J.D.6    Ginsburg, D.7
  • 50
    • 0037146737 scopus 로고    scopus 로고
    • Both u-PA inhibition and vitronectin binding by plasminogen activator inhibitor 1 regulate HT1080 fibrosarcoma cell metastasis
    • Praus M., Collen D., Gerard R.D. Both u-PA inhibition and vitronectin binding by plasminogen activator inhibitor 1 regulate HT1080 fibrosarcoma cell metastasis. Int. J. Cancer. 102:2002;584-591
    • (2002) Int. J. Cancer , vol.102 , pp. 584-591
    • Praus, M.1    Collen, D.2    Gerard, R.D.3
  • 51
    • 0030815119 scopus 로고    scopus 로고
    • Inhibition of metastasis of intraocular melanomas by adenovirus-mediated gene transfer of plasminogen activator inhibitor type 1 (PAI-1) in an athymic mouse model
    • Ma D., Gerard R.D., Li X.Y., Alizadeh H., Niederkorn J.Y. Inhibition of metastasis of intraocular melanomas by adenovirus-mediated gene transfer of plasminogen activator inhibitor type 1 (PAI-1) in an athymic mouse model. Blood. 90:1997;2738-2746
    • (1997) Blood , vol.90 , pp. 2738-2746
    • Ma, D.1    Gerard, R.D.2    Li, X.Y.3    Alizadeh, H.4    Niederkorn, J.Y.5
  • 53
    • 0032993493 scopus 로고    scopus 로고
    • Reduction of tumor cell migration and metastasis by adenoviral gene transfer of plasminogen activator inhibitors
    • Praus M., Wauterickx K., Collen D., Gerard R.D. Reduction of tumor cell migration and metastasis by adenoviral gene transfer of plasminogen activator inhibitors. Gene Ther. 6:1999;227-236
    • (1999) Gene Ther. , vol.6 , pp. 227-236
    • Praus, M.1    Wauterickx, K.2    Collen, D.3    Gerard, R.D.4
  • 54
    • 0028821827 scopus 로고
    • Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model
    • Soff G.A., Sanderowitz J., Gately S., Verrusio E., Weiss I., Brem S., Kwaan H.C. Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model. J. Clin. Invest. 96:1995;2593-2600
    • (1995) J. Clin. Invest. , vol.96 , pp. 2593-2600
    • Soff, G.A.1    Sanderowitz, J.2    Gately, S.3    Verrusio, E.4    Weiss, I.5    Brem, S.6    Kwaan, H.C.7
  • 55
    • 0000124642 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 represses integrin-and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation
    • Kjoller L., Kanse S.M., Kirkegaard T., Rodenburg K.W., Ronne E., Goodman S.L., Preissner K.T., Ossowski L., Andreasen P.A. Plasminogen activator inhibitor-1 represses integrin-and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation. Exp. Cell Res. 232:1997;420-429
    • (1997) Exp. Cell Res. , vol.232 , pp. 420-429
    • Kjoller, L.1    Kanse, S.M.2    Kirkegaard, T.3    Rodenburg, K.W.4    Ronne, E.5    Goodman, S.L.6    Preissner, K.T.7    Ossowski, L.8    Andreasen, P.A.9
  • 56
    • 0030685740 scopus 로고    scopus 로고
    • Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: A gene targeting and gene transfer study in mice
    • Carmeliet P., Moons L., Lijnen R., Janssens S., Lupu F., Collen D., Gerard R.D. Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in mice. Circulation. 96:1997;3180-3191
    • (1997) Circulation , vol.96 , pp. 3180-3191
    • Carmeliet, P.1    Moons, L.2    Lijnen, R.3    Janssens, S.4    Lupu, F.5    Collen, D.6    Gerard, R.D.7
  • 58
    • 0034747099 scopus 로고    scopus 로고
    • TGF-beta1-induced PAI-1 gene expression requires MEK activity and cell-to-substrate adhesion
    • Kutz S.M., Hordines J., McKeown-Longo P.J., Higgins P.J. TGF-beta1-induced PAI-1 gene expression requires MEK activity and cell-to-substrate adhesion. J. Cell Sci. 114:2001;3905-3914
    • (2001) J. Cell Sci. , vol.114 , pp. 3905-3914
    • Kutz, S.M.1    Hordines, J.2    McKeown-Longo, P.J.3    Higgins, P.J.4
  • 59
    • 0034971842 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein 1 stimulates human trophoblast migration by signaling through alpha 5 beta 1 integrin via mitogen-activated protein kinase pathway
    • Gleeson L.M., Chakraborty C., McKinnon T., Lala P.K. Insulin-like growth factor-binding protein 1 stimulates human trophoblast migration by signaling through alpha 5 beta 1 integrin via mitogen-activated protein kinase pathway. J. Clin. Endocrinol. Metab. 86:2001;2484-2493
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 2484-2493
    • Gleeson, L.M.1    Chakraborty, C.2    McKinnon, T.3    Lala, P.K.4
  • 60
    • 0029968743 scopus 로고    scopus 로고
    • Combined overexpression of urokinase, urokinase receptor, and plasminogen activator inhibitor-1 is associated with breast cancer progression: An immunohistochemical comparison of normal, benign, and malignant breast tissues
    • Costantini V., Sidoni A., Deveglia R., Cazzato O.A., Bellezza G., Ferri I., Bucciarelli E., Nenci G.G. Combined overexpression of urokinase, urokinase receptor, and plasminogen activator inhibitor-1 is associated with breast cancer progression: an immunohistochemical comparison of normal, benign, and malignant breast tissues. Cancer. 77:1996;1079-1088
    • (1996) Cancer , vol.77 , pp. 1079-1088
    • Costantini, V.1    Sidoni, A.2    Deveglia, R.3    Cazzato, O.A.4    Bellezza, G.5    Ferri, I.6    Bucciarelli, E.7    Nenci, G.G.8
  • 62
    • 0035860418 scopus 로고    scopus 로고
    • PAI-1 inhibits urokinase-induced chemotaxis by internalizing the urokinase receptor
    • Degryse B., Sier C.F., Resnati M., Conese M., Blasi F. PAI-1 inhibits urokinase-induced chemotaxis by internalizing the urokinase receptor. FEBS Lett. 505:2001;249-254
    • (2001) FEBS Lett. , vol.505 , pp. 249-254
    • Degryse, B.1    Sier, C.F.2    Resnati, M.3    Conese, M.4    Blasi, F.5
  • 63
    • 0032779919 scopus 로고    scopus 로고
    • Inhibitory role of plasminogen activator inhibitor-1 in invasion and proliferation of HLE hepatocellular carcinoma cells
    • Morita Y., Hayashi Y., Kanamaru T., Itoh T., Suzuki S., Yamamoto M., Kuroda Y., Itoh H. Inhibitory role of plasminogen activator inhibitor-1 in invasion and proliferation of HLE hepatocellular carcinoma cells. Jpn. J. Cancer Res. 90:1999;747-752
    • (1999) Jpn. J. Cancer Res. , vol.90 , pp. 747-752
    • Morita, Y.1    Hayashi, Y.2    Kanamaru, T.3    Itoh, T.4    Suzuki, S.5    Yamamoto, M.6    Kuroda, Y.7    Itoh, H.8
  • 64
    • 0029799088 scopus 로고    scopus 로고
    • Contrasting effects of plasminogen activators, urokinase receptor, and LDL receptor-related protein on smooth muscle cell migration and invasion
    • Okada S.S., Grobmyer S.R., Barnathan E.S. Contrasting effects of plasminogen activators, urokinase receptor, and LDL receptor-related protein on smooth muscle cell migration and invasion. Arterioscler., Thromb., Vasc. Biol. 16:1996;1269-1276
    • (1996) Arterioscler., Thromb., Vasc. Biol. , vol.16 , pp. 1269-1276
    • Okada, S.S.1    Grobmyer, S.R.2    Barnathan, E.S.3
  • 65
    • 0030757506 scopus 로고    scopus 로고
    • Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin
    • Waltz D.A., Natkin L.R., Fujita R.M., Wei Y., Chapman H.A. Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin. J. Clin. Invest. 100:1997;58-67
    • (1997) J. Clin. Invest. , vol.100 , pp. 58-67
    • Waltz, D.A.1    Natkin, L.R.2    Fujita, R.M.3    Wei, Y.4    Chapman, H.A.5
  • 66
    • 0029816265 scopus 로고    scopus 로고
    • Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?
    • Deng G., Curriden S.A., Wang S., Rosenberg S., Loskutoff D.J. Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release? J. Cell Biol. 134:1996;1563-1571
    • (1996) J. Cell Biol. , vol.134 , pp. 1563-1571
    • Deng, G.1    Curriden, S.A.2    Wang, S.3    Rosenberg, S.4    Loskutoff, D.J.5
  • 71
    • 0034014726 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor 1 may promote tumour growth through inhibition of apoptosis
    • Kwaan H.C., Wang J., Svoboda K., Declerck P.J. Plasminogen activator inhibitor 1 may promote tumour growth through inhibition of apoptosis. Br. J. Cancer. 82:2000;1702-1708
    • (2000) Br. J. Cancer , vol.82 , pp. 1702-1708
    • Kwaan, H.C.1    Wang, J.2    Svoboda, K.3    Declerck, P.J.4
  • 72
    • 0034667385 scopus 로고    scopus 로고
    • Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1
    • Gutierrez L.S., Schulman A., Brito-Robinson T., Noria F., Ploplis V.A., Castellino F.J. Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1. Cancer Res. 60:2000;5839-5847
    • (2000) Cancer Res. , vol.60 , pp. 5839-5847
    • Gutierrez, L.S.1    Schulman, A.2    Brito-Robinson, T.3    Noria, F.4    Ploplis, V.A.5    Castellino, F.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.